Bone Marrow Transplant

Bone Marrow Transplant

A bone marrow transplant is a medical procedure. This is a type of treatment where the bone marrow in your body is replaced by healthy cells. The cells that are used for replacement are taken from your own body or they are taken from a donor. 

A stem cell transplant is another term used to refer to a bone marrow transplant. Specifically, it is known as a hematopoietic stem cell transfer. There are certain types of cancers such as myeloma, leukemia, dan limfoma that can be treated with a bone marrow transplant. Other blood and immune system diseases that affect the bone marrow are also treated with a bone marrow transplant.  

The procedure of bone marrow transplant involves infusing healthy blood-forming stem cells into your body. These healthy stem cells replace all the damaged or diseased bone marrow in your body. If your bone marrow stops working for some reason and halts the production of adequate healthy red blood cells, then a bone marrow transplant is required. So, CARE Hospitals provide a bone marrow transplant Hospital in Hyderabad with the best medical doctors.

Pengantar Sumsum Tulang dan Sel Punca

There are some special cells in our body known as stem cells. These cells can make copies of themselves and have the ability to change into many separate kinds of cells that are needed by your body. There are many different kinds of stem cells. Each type of stem cell is found in different parts of your body at different times. 

Cancer and cancer treatment targets the cells in your body. They specifically can damage your hematopoietic stem cells. Stem cells that have the ability to turn into blood cells are known as hematopoietic stem cells.

The soft, spongy tissue in our body which contains the hematopoietic stem cells is known as the bone marrow. The location of the bone marrow in the centre of each bone. The blood that is moving throughout our body also contains hematopoietic stem cells. 

Red blood cells, sel darah putih, dan trombosit are not formed from hematopoietic stem cells if they are damaged. The three types of blood cells are very important to our system and each of them has a separate job. They are as follows:-

sel darah merah- Their main job is to carry oxygen throughout the body. Along with transporting oxygen, they also move the carbon dioxide to your lungs so that it can be exhaled. 

Sel darah putih- They are the main constituents of our immune system. Their main job is to fight pathogens. Pathogens are bacteria and viruses that have the ability to make you ill. 

Trombosit- Platelets are related to the formation of pembekuan darah. 

Through the medical procedure of bone marrow or stem cell transplant, healthy stem cells are transplanted into the bone marrow or into the blood. This helps in restoring the body’s ability to create red blood cells, white blood cells, and platelets whenever it is required.

Jenis Transplantasi Sumsum Tulang

Terdapat dua jenis utama transplantasi sumsum tulang, yaitu:

Transplantasi sel induk alogenik- The procedure of allogeneic stem cell transplant involves the use of healthy blood stem cells obtained from a donor to replace the diseased or damaged bone marrow. The allogeneic stem cell transfer is also referred to as the allogeneic bone marrow transplant. 

Pendonornya bisa siapa saja, bisa anggota keluarga, kenalan, atau bisa juga orang asing. Berikut adalah jenis-jenis sel punca darah yang digunakan dalam transplantasi sel punca alogenik: 

• Darah dikumpulkan dari pendonor.

•  The stem cell was collected from the bone marrow of the donor’s hipbone. 

• The stem cells are collected from any umbilical cord that is donated. Collected from the blood of a donated umbilical cord

The body needs to be prepared first before undergoing an allogeneic stem cell transplant. High doses of kemoterapi and radiation are received by the patient before undergoing an allogeneic stem cell transplant. This is done to damage the diseased cells before the body is ready to receive the donor cells

Autologous stem cell transplant- Dalam transplantasi sel punca autologus, sel punca darah sehat dari tubuh pasien sendiri digunakan untuk menggantikan sumsum tulang yang rusak dan sakit di dalam tubuh Anda. Transplantasi sel punca autologus juga dikenal sebagai transplantasi sumsum tulang autologus. 

Metode transplantasi sel punca autologus menawarkan beberapa keunggulan dibandingkan transplantasi sel punca alogenik. Hal ini karena sel punca yang digunakan berasal dari tubuh Anda sendiri. Dalam hal ini, Anda tidak perlu khawatir tentang ketidakcocokan antara sel donor dan penerima.  

Jika tubuh Anda terus memproduksi cukup sel sumsum tulang yang sehat, Anda dapat dengan mudah menjalani transplantasi sel punca autologus. Sel punca sehat dari tubuh Anda dapat dikumpulkan, dibekukan, dan kemudian disimpan untuk digunakan nanti. 

Mengapa Transplantasi Sumsum Tulang Diperlukan?

The uses of bone marrow transplant could be related to these:-

• This allows the safe treatment of your condition by using radiation or chemotherapy. Then bone marrow replacement therapy replaces all the cells that are damaged due to the radiation. 

• Sel induk baru menggantikan semua sumsum tulang yang rusak dan berpenyakit.

• Sel induk baru yang disediakan dapat membantu membunuh sel kanker secara langsung. 

Transplantasi sumsum tulang dapat memberikan manfaat bagi banyak orang. Penderita penyakit kanker maupun non-kanker dapat memperoleh manfaat dari transplantasi sumsum tulang. Berikut beberapa penyakit yang dapat memperoleh manfaat dari transplantasi sumsum tulang: 

• Leukemia akut

• Adrenoleukodistrofi

• Anemia aplastik

• Sindrom kegagalan sumsum tulang

• Leukemia kronis

• Hemoglobinopati

• limfoma Hodgkin

• Kekurangan kekebalan tubuh

• Kesalahan metabolisme bawaan

• Multiple myeloma

• Sindrom Myelodysplastic

• Neuroblastoma

• Limfoma non-Hodgkin

• Kelainan sel plasma

• PUISI sindroma

• Amiloidosis primer

Apa Risiko Transplantasi Sumsum Tulang?

Numerous risks are posed by a bone marrow transplant. Some people get away with a bone marrow transplant with minimal complications or no complications and some people face some serious complications. In rare cases, these complications could also be life-threatening. The particular risks that a person faces depend on many different factors. This includes the type of disease or condition that makes you require a transplant, your age, and your medical history. 

Kemungkinan komplikasi dari transplantasi sumsum tulang meliputi:

• Penyakit graft-versus-host (hanya transplantasi alogenik)

• Kegagalan sel induk (cangkok).

• Kerusakan organ

• Infeksi

• Katarak

• Infertilitas

• Kanker baru

• Kematian

Dokter Anda akan menjelaskan risiko yang mungkin Anda hadapi jika menjalani transplantasi sumsum tulang. Anda dapat mendiskusikan risiko transplantasi sumsum tulang dengan dokter Anda dan memutuskan untuk menjalaninya. 

Bagaimana Rumah Sakit CARE Dapat Membantu?

At CARE Hospitals, we have the advanced technologies and the latest instruments to diagnose your condition precisely and provide you with the best treatment plans. You will be in the best hands if you are under the care of CARE hospitals as we are one of the Best hospitals for bone marrow transplantation in Hyderabad. Click Here for Biaya Transplantasi Sumsum Tulang details in India.