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Citalopram

Citalopram, a widely prescribed antidepressant, has become a crucial tool in treating depression and කාංසාව disorders. This drug, often available as citalopram tablets, has gained popularity for its effectiveness in balancing brain chemistry and improving mood.

Let's explore the world of this medicine and learn how citalopram works, its benefits, potential side effects, and important considerations for those using or considering this treatment. 

What is Citalopram?

Drug citalopram is a powerful antidepressant medication that belongs to the drugs categorised as selective serotonin reuptake inhibitors (SSRIs). This medication has gained widespread use due to its efficacy in treating major depressive disorder and other mental health conditions. The primary function of citalopram is to increase serotonin levels, a natural chemical compound in the brain. 

Citalopram Uses

Drug citalopram tablets have gained widespread use in the treatment of various mental health conditions. 

  • Their primary application is in the management of depression, particularly major depressive disorder (MDD). 
  • As a Selective Serotonin Reuptake Inhibitor (SSRI), citalopram works by elevating the serotonin levels in the human brain. By enhancing serotonergic transmission, citalopram helps to alleviate symptoms related to depression and other mood disorders.
  • While depression is the primary indication for citalopram use, doctors may also prescribe it for other mental health conditions. These can include:

How to Use Citalopram Tablets

To ensure the better outcomes, patients should follow these guidelines:

  • Take the drug citalopram exactly as prescribed by the doctor.
  • Do not consume more than the recommended dose or exceed the duration of treatment.
  • Be patient, as it may take up to a month or longer to notice improvements.
  • If using the oral solution, shake the bottle well and use a marked measuring device for accurate dosing.
  • Patients should take a dose as soon as they remember if a dose is missed. However, if it's almost time for the next dose, they should skip the missed one and continue their regular schedule. 

Side Effects of Citalopram Tablets

පොදු අතුරු ආබාධ ඇතුළත් වේ:

  • වියළි මුඛය
  • අධික දහඩීම
  • නින්ද කැළඹීම්
  • තෙහෙට්ටුව හෝ දුර්වලකම
  • යවන
  • Muscle aches and joint stiffness
  • හිසරදය
  • ඔක්කාරය
  • ලිංගික ගැටළු
  • Respiratory infections, such as sinus infection or infection of the nose and throat

Patients should immediately get medical guidance if they experience the following:

  • ඔසප් කාල පරිච්ඡේදවල වෙනස්කම්
  • පැහැදිලි කළ නොහැකි බර වැඩිවීම හෝ අඩු වීම
  • Bleeding from the gums or unexplained bruising
  • Strong feelings of happiness or restlessness
  • Coughing up blood or මුත්රා වල රුධිරය
  • Black or red stools or blood in vomit

Patients should call emergency if they experience:

  • පපුවේ වේදනාව හෝ හුස්ම හිරවීම
  • අල්ලා ගැනීම් හෝ ගැලපීම්
  • දැඩි ක්ලාන්තය හෝ ක්ලාන්තය
  • Prolonged, painful erections
  • Heavy bleeding that doesn't stop within 10 minutes
  • ස්වයං හානියක් හෝ සියදිවි නසාගැනීමේ සිතුවිලි
  • Signs of low sodium levels (headaches, trouble focusing, memory problems, weakness)

පූර්වාරක්ෂාව

When taking the drug citalopram, patients must be aware of several essential precautions to ensure their safety and the medication's effectiveness. 

  • Regular meetings with a doctor to monitor progress and adjust the dosage if necessary 
  • It's important not to stop taking citalopram abruptly without consulting a doctor. Gradual reduction of the dosage is typically recommended to avoid withdrawal symptoms such as agitation, dizziness, nausea, and headaches.
  • The medication can also cause hyponatremia (low sodium levels in the blood), particularly in elderly patients or those taking diuretics. Symptoms of hyponatremia include confusion, headache, and weakness.
  • Patients with certain health conditions should exercise caution when taking the drug citalopram. These conditions include:
    • මානසික අවපීඩනය
    • වකුගඩු අක්රිය වීම
    • අක්මා රෝගය
    • මැෙනියා
    • අල්ලා ගැනීමේ ආබාධ
    • QT දිගු කිරීම
    • බර අඩුවීම

How Citalopram Tablet Works

Citalopram, a selective serotonin reuptake inhibitor (SSRI), works by surging the serotonergic activity in the central nervous system (CNS). The mechanism of action involves the inhibition of serotonin reuptake in the CNS. Citalopram blocks the serotonin transporter (SLC6A4), preventing serotonin reabsorption into neurons. This action leads to an increase in extracellular serotonin levels, allowing for improved communication between brain cells.

When a person starts taking citalopram, the drug immediately begins to block serotonin transporters. This blockade causes an acute increase in serotonin levels in the synaptic cleft. 

Can I Take Citalopram with Other Medicines?

Certain medications can interact with citalopram, potentially increasing the possibility of side effects or altering its effectiveness. Here are some key interactions to be aware of:

  • රුධිර තුනී කරන්නන්: Citalopram can enhance the risk of bleeding when combined with antiplatelet or anticoagulant medications.
  • හෘද ඖෂධ: Some antiarrhythmic drugs can interact with citalopram, affecting heart rhythm.
  • Migraine Medications: Triptans, such as sumatriptan, may increase the risk of serotonin syndrome when taken with citalopram.
  • මොනොඇමයින් ඔක්සිඩේස් නිෂේධක (MAOIs): These medications, used for depression or පාකින්සන් රෝගය, should not be taken within two weeks of starting or stopping citalopram. 
  • වෙනත් විෂාදනාශක: SSRIs, SNRIs, and tricyclic antidepressants can interact with citalopram, potentially increasing the risk of serotonin syndrome.
  • වේදනා ඖෂධ: Certain opioids, like tramadol, methadone, or fentanyl, can interact with citalopram.
  • ඖෂධීය අතිරේක: St. John's Wort can raise serotonin levels and should be avoided while taking citalopram.
  • වෙනත් ඖෂධ: Pimozide (used for Tourette syndrome), buspirone (for anxiety), and amphetamines (for ADHD) can also interact with citalopram.

මාත්‍රා තොරතුරු

For adults with depression, doctors typically prescribe an initial dose of 20 mg once daily. 

The starting dose may be lower in some cases, such as preventing භයානක ප්රහාරයන් ය. Adults usually begin with 10 mg once daily in this situation. 

නිගමනය

Citalopram has a significant impact on the lives of many individuals struggling with depression and කාංසාව. Its ability to boost serotonin levels in the brain helps to alleviate symptoms and improve overall mood. While it's a powerful tool in mental health treatment, it's crucial to remember that citalopram, like any medicine, comes with potential side effects and interactions that need careful consideration.

By understanding how citalopram works, its benefits, and potential complications, patients can make informed decisions about their mental health treatment. Remember, seeking help and starting treatment is a brave step towards better mental health and well-being.

නිතර අසන ප්රශ්න

1. What is citalopram mainly used for?

Citalopram is primarily used to treat depression in adults 18 years or older.

2. Who needs to take citalopram?

People diagnosed with major depressive disorder are the primary candidates for citalopram treatment. However, doctors may also prescribe it for patients suffering from anxiety disorders, panic attacks, or obsessive-compulsive disorder. In some cases, doctors might recommend citalopram for specific symptoms like postmenopausal flushing. 

3. Should I take citalopram daily?

Yes, citalopram is typically taken once daily. Patients can take it at any time of day, but it's best to stick to the same time every day for consistency. 

4. Who can't take citalopram?

Citalopram is contraindicated for certain groups of people. These include:

  • Patients taking monoamine oxidase inhibitors (MAOIs)
  • Individuals using pimozide, urokinase, methylene blue, linezolid, or dapoxetine
  • People with hypersensitivity to citalopram or its excipients
  • සංජානනීය දිගු QT සින්ඩ්‍රෝමය ඇති රෝගීන්

5. Can I stop citalopram anytime?

No, patients should not stop taking citalopram abruptly or without consulting their doctor. Sudden discontinuation can cause withdrawal symptoms:

  • මෝහනය
  • කාංසාව
  • නින්ද නොයාම
  • චිත්තවේගීය අස්ථාවරත්වය
  • හිසරදය
  • පාචනය
  • වමනය
  • උකුස්සන්

6. What is the most common side effect of citalopram?

පොදු අතුරු ආබාධ ඇතුළත් වේ:

  • වියළි මුඛය
  • අධික දහඩීම
  • නින්ද කැළඹීම්
  • තෙහෙට්ටුව හෝ දුර්වලකම
  • හිසරදය
  • ඔක්කාරය

7. Is citalopram used for stress?

While citalopram is not specifically prescribed for stress, it may help manage stress-related symptoms associated with depression or anxiety disorders. 

8. Is citalopram a strong antidepressant?

Citalopram is considered an effective antidepressant, but its strength can vary depending on individual response. 

9. Is citalopram bad for your heart?

Citalopram can affect heart rhythm, potentially causing QT prolongation in some patients. This effect is dose-dependent, meaning higher doses carry a greater risk. 

වියාචනය: මෙහි සපයා ඇති තොරතුරු සෞඛ්‍ය සේවා වෘත්තිකයෙකුගේ උපදෙස් ආදේශ කිරීමට අදහස් නොකෙරේ. මෙම තොරතුරු සියලු විය හැකි භාවිතයන්, අතුරු ආබාධ, පූර්වාරක්ෂාවන් සහ ඖෂධ අන්තර්ක්‍රියා ආවරණය කිරීමට අදහස් නොකෙරේ. නිශ්චිත ඖෂධයක් භාවිතා කිරීම ඔබට හෝ වෙනත් ඕනෑම කෙනෙකුට සුදුසු, ආරක්ෂිත හෝ කාර්යක්ෂම බව යෝජනා කිරීමට මෙම තොරතුරු අදහස් නොකෙරේ. ඖෂධය පිළිබඳ කිසිදු තොරතුරක් හෝ අනතුරු ඇඟවීමක් නොමැති වීම සංවිධානයෙන් ලැබෙන ව්‍යංග සහතිකයක් ලෙස අර්ථ නිරූපණය නොකළ යුතුය. ඔබට ඖෂධය පිළිබඳ කිසියම් ගැටළුවක් ඇත්නම් වෛද්‍යවරයෙකුගෙන් උපදෙස් ලබා ගන්නා ලෙසත්, වෛද්‍යවරයෙකුගේ බෙහෙත් වට්ටෝරුවකින් තොරව කිසි විටෙකත් ඖෂධ භාවිතා නොකරන ලෙසත් අපි ඔබට තරයේ අවවාද කරමු.