Sonke siyawazi umthelela we sokuqaqamba kwamalunga ezimpilweni zethu zansuku zonke. Ubhekene ubuhlungu, ukuqina, nokuhamba okulinganiselwe kungaphazamisa kakhulu ikhono lethu lokwenza imisebenzi elula njengokugqoka, ukupheka nokuhambahamba. Kodwa-ke, ukuhlonza okufika ngesikhathi kanye nokwelashwa kungasiza ekuvimbeleni ukulimala okuhlala njalo kwe amalunga omzimba. I-Anti-CCP Test (Anti-cyclic citrullinated peptide) ivele njengethuluzi lokuthola I-Rheumatoid Arthritis. Kulesi sihloko, sizocubungula imininingwane yokuhlolwa kwe-anti-CCP, ukubaluleka kwayo, lapho kufanele ukuthi uhlolwe, inqubo, kanye nemiphumela yemiphumela yokuhlolwa.

Ukuqonda Ukuhlolwa Kwe-Anti-CCP

Ukuhlolwa kwegazi okulwa ne-CCP kubizwa nangokuthi i-anti-cyclic citrullinated peptide test. Lokhu kuhlola kuvumela umhlinzeki wakho wokunakekelwa kwezempilo ukuthi athole amasosha omzimba aqondise ama-peptide e-citrullinated cyclic ngaphakathi kwesistimu yakho. Lawa ma-anti-CCP ayizinkomba ze-rheumatoid arthritis futhi ngokuvamile akhona kubantu abatholakala benalesi simo.

Inhloso Yokwenza Ukuhlolwa Kwegazi Kwe-Anti-CCP

Ngokusebenzisa ukuhlolwa kwe-CCP, udokotela wakho angabona I-Rheumatoid Arthritis ezigabeni zayo. Ingathola amasosha omzimba ngisho nangaphambi kokuba kuvele noma yiziphi izimpawu. Ukuthola lesi sifo ekuqaleni kwaso kungaholela ekwelapheni ngokushesha futhi kuvimbele ukulimala kwamalunga unomphela.

Kudingeka Nini Ukuhlolwa Kwe-Anti-CCP?

Udokotela wakho angase atuse ukuhlolwa kwe-anti-CCP uma ufika nezikhalazo zobuhlungu obuhlangene obuqhubekayo, ukuvuvukala, nokuqina, ikakhulukazi emalungeni amancane ezandla, izihlakala, kanye izinyawo. Udokotela anga-oda lokhu kuhlolwa ku:

Hlukanisa i-RA kwezinye izinhlobo ze-arthritis.

• Hlola ukuqina kwesifo futhi uqaphe ukuqhubeka.
• Usizo ezinqumweni zokwelashwa, okuhlanganisa ukuqaliswa noma ukulungiswa kwemithi eqondene ne-RA.
• Linganisa ukusebenza kokwelashwa kwe-RA ngokuhamba kwesikhathi. 

Kwenzekani Ngesikhathi Senqubo Yokulwa Ne-CCP?

Inqubo ye-Anti-CCP ukuhlolwa kwegazi okulula lapho uchwepheshe wezokunakekelwa kwempilo eqoqa isampula yegazi emthanjeni osengalweni yakho. Inqubo ibandakanya lezi zinyathelo ezilandelayo:

• Ukuqoqwa kwesampula yegazi: Izisebenzi zezokwelapha zizodonsa inani elincane lesampula yegazi emthanjeni osengalweni yakho zisebenzisa inaliti, isirinji, noma ivacutainer. Odokotela bathumela isampula yegazi elabhorethri ukuze lihlaziywe ngemva kokuqoqwa kwesampula. 
• Ukuhlola okuyisampula: Ochwepheshe baselabhorethri bahlola isampula yegazi ukuze bathole amasosha omzimba ngokumelene nama-peptide e-cyclic citrullinated besebenzisa izindlela ezithile, njenge-chemiluminescent immunoassay (CIA) noma i-enzyme-linked immunosorbent assay (ELISA). 
• Ilabhorethri izohlinzeka ngemiphumela yokuhlolwa kubasebenzi bakho bezokwelapha. Udokotela uzotolika imiphumela kanye nomlando wakho wezokwelapha, izethulo ezinezimpawu, nokunye ukuhlola kokuxilonga.

Ukusetshenziswa kokuhlolwa kwe-Anti-CCP

Odokotela basebenzisa ukuhlolwa kwe-Anti-CCP ekuhlonzeni nasekulawuleni isifo samathambo. Lokhu kubandakanya:

• Ukuxilongwa: Ukuhlolwa kusiza ukuqinisekisa ukutholakala kwe-arthritis ye-rheumatoid, ikakhulukazi ezimweni lapho ezinye izindlela zokuxilonga zingase zingafinyeleli.
• I-prognosis: Amazinga aphezulu amasosha omzimba e-CCP ahlotshaniswa nesifo esibi kakhulu kanye namathuba aphezulu okulimala kwamalunga. Ukuhlolwa kungasiza ekunqumeni ukubikezelwa kwesifo.
• Ukuqapha umsebenzi wesifo: Ukuhlolwa kwe-Anti-CCP kuhlola ukuqhubeka kwesifo kanye nokusabela kokwelashwa kubantu abatholakala bene-rheumatoid arthritis. 

Isho Ukuthini Imiphumela Yokuhlolwa Kwe-Anti-CCP?

Ilabhorethri ihlinzeka ngemiphumela yokuhlola emelene ne-CCP kumayunithi, futhi odokotela bayihumusha ngokusekelwe kunkomba yohlu lokuhlola lwe-CCP lwelebhu. Amazinga aphansi amasosha omzimba alwa ne-CCP angase asho avamile, kuyilapho amazinga aphezulu kunokuvamile abonisa isifo samathambo, ikakhulukazi uma sihambisana nezimpawu ezinjengobuhlungu bamalunga, ukuvuvukala, nokuqina. 

Isho Ukuthini Imiphumela Engavamile

Uma imiphumela yokuhlolwa ingaphezulu kwebanga elivamile le-anti-CCP, kuphakamisa amathuba amakhulu e-Rheumatoid Arthritis. Kodwa-ke, akuqinisekisi ukuxilongwa futhi odokotela kufanele bacabangele ezinye izimpawu zomtholampilo kanye nokutholwe ngelebhu ukuze baqinisekise i-RA. 

Isiphetho

Ukuhlolwa kwe-Anti-CCP kuguqule ukutholwa kusenesikhathi kwe-Rheumatoid Arthritis, okuvumela ukuxilonga okufika ngesikhathi nokungenelela. Ukuzwela okuphezulu kanye nokucaciswa kwalokhu kuhlolwa kukwenza kube ithuluzi elibalulekile ekuhlukaniseni i-RA kwezinye izinhlobo ze-arthritis. Ukutholwa kusenesikhathi nokungenelela okufika ngesikhathi kungasiza ukulawula izimpawu, kuvimbele ukuwohloka kwamalunga, futhi kuthuthukise ikhwalithi yokuphila iyonke yabantu abane-arthritis ye-rheumatoid.

FAQ sika

1. Ingabe ukuhlolwa kwe-CCP kudinga ukuzila ukudla?

Cha, ukuzila ukudla akudingekile ngaphambi kokuhlolwa kwe-anti-CCP. 

2. Iliphi izinga elijwayelekile lokuhlolwa kwe-CCP?

Ibanga elijwayelekile lokuhlola i-CCP lokuhlola linomphumela ongaphansi kwama-20 EU/ml (Amayunithi e-Enzyme ngemililitha). Nokho, lokhu kungase kuhluke kancane phakathi kwezinsiza ezahlukene. Amazinga aphansi amasosha omzimba alwa ne-CCP ngokuvamile abhekwa njengejwayelekile, kuyilapho amanani aphezulu kunohlu oluvamile lwe-anti-CCP abonisa isifo samathambo.

3. Kwenzekani uma i-anti-CCP Test ithi positive?

Umphumela omuhle ekuhlolweni kwe-Anti-CCP uphakamisa amathuba aphezulu okuba ne-rheumatoid arthritis. Kodwa-ke, ukuhlolwa okuqhubekayo nokubonisana ne-rheumatologist kubalulekile ukuze kuqinisekiswe ukuxilongwa.

4. Kwenzekani uma ukuhlolwa kwe-CCP kungenayo?

Umphumela ongemuhle ekuhlolweni kwe-Anti-CCP awubandakanyi amathuba okuba nesifo samathambo. Ezinye izindlela zokuxilonga kanye nokuhlolwa komtholampilo kuyadingeka ukuze kutholakale ukuxilongwa okuqinisekile.

5. Yimaphi amapharamitha akalwa ekuhlolweni kwe-Anti-CCP?

Ukuhlola kukala amazinga avamile e-anti-CCP ezivikelamzimba eziqondiswe kuma-peptide e-citrullinated cyclic egazini.

6. Kuthatha Isikhathi Esingakanani Ukuhlolwa Kwe-Anti-CCP?

Ukwenza ukuhlolwa kwe-Anti-CCP kuthatha imizuzu embalwa kuphela, kodwa ukuthola imiphumela kungase kudinge izinsuku ezimbalwa.