Ukuhlolwa kwe-ASO kuphakanyiswe ukuthola ukutheleleka nge-strep. Leli thuluzi lokuxilonga libhekwa njengelisebenzayo ekuxilongeni isimo, nokudala uhlelo lokwelapha olulandelayo.

Kuyini ukuhlolwa kwe-ASO?

I-antistreptolysin O (ASO) titer test wuhlobo lokuhlolwa kwegazi, olwenziwa ngokukhethekile ukuze kutholwe izifo ze-strep. Ikwenza nge ukukala amasosha omzimba adalwe umzimba ngokuphendula ubuthi obubizwa ngokuthi i-streptolysin O. Amagciwane eqembu A Streptococcus (GAS) abangela ukuthi umzimba ukhiqize lawa magciwane. Uma umuntu ene-strep infection ebangelwa amabhaktheriya e-GAS, umzimba uzokhiqiza ama-antistreptolysin O antibodies.

Endabeni ye-strep throat, ama-antibiotics aphakanyiswa ukusiza ukubulala amabhaktheriya futhi aqede. Kodwa, ngezinye izikhathi, ukutheleleka nge-strep akubonisi noma yiziphi izimpawu, okubangela ukubambezeleka kokwelashwa. Lokhu kungadala izinkinga esikhathini esizayo. Ngosizo lokuhlolwa kwe-ASO titer, udokotela angakwazi ukunquma ukuthi isiguli siye sabhekana nokutheleleka kwe-strep muva nje noma uma ama-antistreptolysin antibodies ekhona egazini. 

Kufanele Uthole Nini Ukuhlolwa Kwe-ASO?

Odokotela bavame ukuphakamisa ukuhlolwa kwe-ASO uma isiguli sinezimpawu zezinkinga ze-post-streptococcal ezifana ne-bacterial endocarditis, glomerulonephritis, kanye umkhuhlane we-rheumatic. Kuthatha umzimba amaviki angu-3 kuya kwangu-8 ukuze amasosha omzimba e-antistreptolysin afinyelele emazingeni aphezulu ngemva kokutheleleka nge-strep. Ngokuhlola amazinga e-antibody, udokotela angakwazi ukuthola ukuthi izimpawu isiguli esinazo zingabangelwa yini izinkinga ze-post-streptococcal.

Inqubo yokuhlolwa kwe-ASO

Ukuze uthole ukuhlolwa kwe-ASO Titer, ukuqoqa isampula yegazi kuyadingeka. Ukuhlolwa kwegazi kwenziwa ngu-a uchwepheshe lab njengoba benekhono lokuthola isampula yegazi. Igazi lithathwa emthanjeni otholakala engalweni yangaphakathi noma esandleni. Inaliti ifakwa kahle emthanjeni ukuze kudonswe isampula yegazi, bese liqoqwa ngeshubhu elikhethekile elenzelwe le njongo. Ngemva kokudweba isampula yegazi lokuhlolwa kwe-ASO, ishubhu eliqukethe isampula yegazi lithunyelwa ngokucophelela elabhorethri ukuze lihlaziywe ngokuphelele.

Ngemva kokuhlaziywa, udokotela noma isiguli sithola imiphumela. Ngokwesisekelo semiphumela yokuhlolwa, umhlinzeki wezokunakekelwa kwempilo wabelana ngemininingwane ngesimo sezokwelapha futhi uqondisa isiguli kunoma yiziphi izinyathelo ezengeziwe ezidingekayo noma ukwelashwa. Le nqubo iqinisekisa ukuthi isiguli sinolwazi oluphelele ngempilo yaso nokuthi yini okufanele siyilindele ngemva kwalokho. 

Uzilungiselela Kanjani Ukuhlolwa kwe-ASO?

Umhlinzeki wokunakekelwa kwezempilo uzohlinzeka ngemiyalelo ethile mayelana nanoma imaphi amalungiselelo adingekayo okuhlolwa kwe-ASO titer. Iziguli zingase zelulekwe ukuthi zigweme ukudla noma iziphuzo isikhathi esingamahora ayisithupha ngaphambi kokuhlolwa. Ngaphezu kwalokho, udokotela angase asikisele ukugwema ukusetshenziswa kwemithi ethile ngaphambi kokuhlolwa kwe-ASO. Kubalulekile ukwazisa udokotela ngemithi ephuzwayo ngesikhathi sokuhlolwa okuhlanganisa nemithi etholakala ekhawuntareni kanye nekadokotela. 

Noma yiluphi olunye ulwazi oluphathelene nezinguquko zendlela yokuphila, oluphakanyiswe udokotela kufanele futhi lulandelwe isiguli ukuze kuqinisekiswe imiphumela yokwelashwa efanele kanye nezinkinga ezincane. 

Amanani wemiphumela yokuhlolwa kwe-ASO

Ukuqonda imiphumela yokuhlolwa kwe-ASO kubalulekile ezigulini futhi ukuze zikwazi ukuqonda imiphumela. Kubalulekile ukuqaphela ukuthi ububanzi bemiphumela bungase buhluke ngokwehlukene ama-diagnostic labs. Ukuhlolwa okuvamile kwe-ASO kwehla ngaphansi kwama-200. Nokho, ezinganeni ezingaphansi kweminyaka engu-5 ubudala, kufanele zibe ngaphansi kuka-100. Uma imiphumela yokuhlolwa ibonisa inani eliphakeme le-ASO, ingase ibonise ukuba khona kwenkinga ye-post-streptococcal.

Kwesinye isikhathi, ukuze aqinisekise imiphumela, udokotela angase akhethe ukuphinda ukuhlolwa phakathi nenkathi eyizinsuku eziyi-10 kuye kweziyi-14 njengoba amasosha omzimba e-ASO evamise ukuvela phakathi nesonto ngemva kokuqala kokutheleleka. Uma kokubili ukuhlolwa kubuyisela imiphumela engemihle, kuphakamisa ukuthi ukutheleleka kwe-Streptococcus akubangeli izimpawu. Ezimweni ezinjalo, udokotela angase aqhube nezinye izivivinyo ukuze ahlole imbangela yezimpawu. 

Uma umphumela wokuhlolwa ukhombisa amazinga aphakeme ezivikelamzimba ze-ASO, kungase kube inkomba yokutheleleka kwakamuva. Ngakolunye uhlangothi, amazinga aphansi e-antibody aphakamisa ukuthi ukutheleleka kuyathuthuka. 

Ungayilawula kanjani i-ASO Titer ephezulu

Uma imibiko iveza amazinga aphezulu e-ASO titer, isiguli sidingeka ukuthi sithathe izinyathelo zokuyehlisela ezingeni elivamile. Nakhu okungenziwa ukulawula amazinga aphezulu e-ASO titer: 

• Xhumana nomhlinzeki wokunakekelwa kwezempilo ukuze uqinisekise ukuthi ukutheleleka kwe-streptococcal kukhona yini.
• Thatha imithi ephakanyiswe udokotela njengoba kunqunyiwe futhi ngaphandle kokwehluleka. 
• Inkambo yama-antibiotic kufanele iqedwe. 
• Imithi etholakala ngaphandle kwekhawunta ingasetshenziswa ukuphatha izimpawu uma kudingeka.
• Phumula ngokuphelele ukuze uvumele umzimba ukuthi ululame ekuthelelekeni.
• Phuza amanzi amaningi futhi uhlale unamanzi ukuze ukhuthaze ukululama.
• Landela udokotela ukuze uthole ukuhlolwa okwengeziwe nokunakekelwa njengoba kudingeka.

Imibuzo Evame Ukubuzwa

1. Kusho ukuthini "i-ASO positive"?

"I-ASO positive" ibhekisela kumphumela omuhle ekuhlolweni kwe-titer ye-Antistreptolysin O (ASO). Lokhu kubonisa amazinga aphakeme amasosha omzimba e-ASO egazini, okusho ukutheleleka kwakamuva noma kwamanje nge-Group A Streptococcus (GAS) amagciwane. Leli gciwane lingaholela ezifweni ezihlukahlukene, okuhlanganisa i-strep throat nezinye izifo ze-streptococcal.

2. Ingabe i-ASO ingasetshenziswa ukuxilonga i-strep throat?

Ngokuvamile, i-ASO titer ayisetshenziswa njengendlela eyinhloko yokuxilonga i-strep throat. I-strep throat ivame ukutholakala ngokusebenzisa ukuhlolwa kwe-strep okusheshayo, eyaziwa nangokuthi i-throat swab noma isiko lomphimbo. Lokhu kuhlola kusiza ukuthola ukuba khona kwebhaktheriya ye-GAS emphinjeni. Ukuhlolwa kwe-ASO titer kuthathwa njengokuwusizo kakhulu ekuhlonzeni izifo ezidlule ze-streptococcal noma ukuhlola ubungozi bezinkinga ze-post-streptococcal.

3. Ingabe i-ASO positive isho isifo samathambo?

Inhloso yokuhlolwa kwe-ASO ukukala ubukhona bamasosha omzimba (ASO antibodies) akhiqizwa umzimba ngokuphendula ukutheleleka kwe-streptococcal, futhi angeke abonise ukuthi isifo samathambo. Kodwa, kufanele kuqashelwe ukuthi izifo ze-streptococcal ezingalashwa, ikakhulukazi lezo eziholela emkhuhlaneni we-rheumatic, zingabangela ukuvuvukala kwamalunga kanye nesifo samathambo. Kodwa, umphumela omuhle we-ASO wodwa awusho ngokuqondile ukuthi isiguli sinesifo samathambo.