Ukuhlolwa kwegazi kwe-ferritin ukuhlolwa kwe-serological okuhlinzeka ngesilinganiso samaprotheni e-ferritin kusampula yegazi, elivame ukusetshenziswa abahlinzeki bezempilo ngezinjongo zokuxilonga. I-Ferritin iphrotheni etholakala kumangqamuzana egazi abomvu (RBCs) asebenza njengendawo yokugcina insimbi. Ukuthola okukhulu noma ngaphansi kwenani elijwayelekile le-ferritin egazini kungase kube inkomba yesimo sezempilo esibucayi okufanele siqhutshwe uphenyo ngokuhlolwa okwengeziwe.

Iyini i-Ferritin Test?

Inani elikhona le-ferritin, elingaphezulu noma elingaphansi kwesibalo esivamile se-ferritin, liboniswa ngokuhlolwa okuzinikele kwe-ferritin. I-Ferritin iyisitolo sokusansimbi, okuyisakhi esibalulekile esibalulekile ekudalweni kwamangqamuzana egazi abomvu anempilo kanye nokusatshalaliswa komoyampilo kuhlelo olubanzi lwezinqubo zomzimba. Ukuba namaphrotheni amancane kakhulu noma amaningi kakhulu kungase kubonise ezindabeni zezempilo ezingase zibonise izimpawu ezihambisana nazo kumuntu othintekile. Ngakho, amazinga anjalo angase enze odokotela baqhubeke behlola isimo sensimbi, okungase kuholele ekuxilongeni izifo noma izimo umuntu angase aphathwe ngazo.

Inhloso yokuhlolwa kweFerritin

Ukuhlolwa kwegazi kwe-ferritin kusiza ukunquma ukuthi umzimba womuntu uyawagcina yini amanani ajwayelekile e-ferritin. Ngokuvamile kuhlolwa ngesikhathi sokuhlolwa okuphelele kokusebenza kwesibindi noma izifundo zensimbi ukuze kuphenywe izimbangela zezimpawu ezivezwa ngumuntu. Nokho, umphumela wokuhlolwa kwe-ferritin ungase uhunyushwe wona ngokwawo.

Ngaphezu kokuxilongwa, ukuhlolwa kwe-ferritin kungase kusetshenziswe ngenjongo yokuhlola nokuqapha izimo ezithile zempilo, njenge:

• I-anemia: Ukuba namazinga e-iron (fe) aphansi ngokungaguquki kungase kuqhubekele phambili iron ukuntula i-anemia. Ukuba nensimbi ephansi emzimbeni kungase kuthinte kabi ukukhiqizwa kwamangqamuzana abomvu egazi, okungase kuvimbe amandla okusabalalisa umoya-mpilo emisipha nasezithweni.
• I-ayoni Eningi: Amazinga aphezulu e-Fe egazini aholela esimweni esaziwa ngokuthi i-hemochromatosis. Umzimba awunawo indawo engokwemvelo yokukhipha insimbi; ngenxa yalokho, ifakwa ezicutshini zangaphandle zezitho ezifana ne- isibindi nama-pancreas. Kungase futhi kubangele ukulimala kulezo zitho.
• Isifo Sesibindi: I-ayoni ngobuningi igcinwa kumaprotheni e-ferritin esibindini. Endabeni yesifo sesibindi noma ukulimala, lokhu kungavuza insimbi egazini. Ngakho-ke, ukuhlolwa kwe-ferritin kungase kubone amazinga aphezulu e-ferritin angasiza ekuhloleni izimo zesibindi ngenxa yokusebenzisa kabi utshwala kanye ukutheleleka nge-hepatitis.

Ngaphandle kwalezi zimo, ukuhlolwa kwe-ferritin kungase futhi kukwazi ukuhlobana uma i-Restless Legs Syndrome (RLS) kanye ne-Adult-Onset Still's Disease (AOSD) kungenxa yokuntuleka kwe-iron noma i-ferritin.

Kudingeka Nini Ukuhlolwa Kwe-Ferritin?

Ukuhlolwa kwe-ferritin kungase kukwazi ukuphonsa ukukhanya phezu kokuntuleka kwensimbi noma ukugcwala ngokweqile uma kunezimpawu ezihambisanayo. Kungase kube nezinhlobonhlobo zezimpawu ezitholwa umuntu onokuntuleka kwensimbi, okuhlanganisa:

• isiyezi
• Ukuphelelwa umoya
• Ukukhathala
• Ukuphaphatheka kwesikhumba
• Ukuphathwa yikhanda
• Ukuzizwa ukhathele njalo isikhathi eside
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• I-Restless legs syndrome
• Ukuvuvuka kolimi
• Ukulangazelela okungajwayelekile ezintweni ezingezona ukudla njengephepha noma iqhwa

Abantu abanamazinga aphezulu e-ferritin bangase bahlangabezane nalokhu okulandelayo:

• Ukukhathala noma ubuthakathaka
• ubuhlungu Joint
• Ukushaya kwenhliziyo okungavamile
• Isikhumba esimpunga noma esinombala wethusi
• Ubuhlungu besisu

Kwenzekani Ngesikhathi Sokuhlolwa Kwe-Ferritin?

Ukuhlolwa kwe-ferritin kuhilela ukusebenzisa isampula yegazi ukuze kuhlolwe elabhorethri futhi kunikeze ukuhlolwa komthamo we-ferritin kuyo. Imiphumela yokuhlolwa ibonisa amazinga e-ferritin atholiwe ngokuphathelene nenani elivamile le-ferritin egazini ukuze lisetshenziswe. 

Ukusetshenziswa kwe-Ferritin Test

Ukuhlolwa kwe-ferritin kungase kube nezinhlobonhlobo zezinhlelo zokusebenza ngaphandle kokunquma inani le-ferritin noma i-iron elikhona kusampula yegazi. Lokhu kubandakanya:

• Ukuhlola noma ukuqinisekisa ukuntuleka kwe-iron anemia
• Iqapha amazinga e-iron kubantu abanezifo ezingamahlalakhona ezithinta amazinga okusansimbi noma kulabo abathatha izithasiselo zensimbi noma abathola ukwelashwa okusansimbi.
• Ihlola ukudla okunomsoco kanye nokumuncwa kwe-iron.
• Ihlola ukusebenza kwesitho esifana nesesibindi.
• Ihlonza noma iqaphe izifo ezinjenge-restless legs syndrome kanye nesifo se-adult-start Still's.

Ungalungiselela kanjani ukuhlolwa kwe-Ferritin?

Nakuba inani le-ferritin egazini lingathinteki ekusetshenzisweni kokudla, ezinye izifundo zensimbi zingadinga ukulungiswa okuqondile. Ukuthi umuntu udinga ukuzila ukudla ngaphambi kokuhlolwa noma cha kuzokwaziswa udokotela othintekayo, kuye ngemfuneko yokuhlolwa.

Inqubo Yokuhlola I-Ferritin

Ukuhlolwa kwe-ferritin kwenziwa ngesampula yegazi elithathwa emthanjeni osengalweni yangaphambili. Ngaphambi kokuba igazi likhishwe engalweni, ibhande lingase libekwe eduze kwengalo ukuze lidale umfutho futhi likhulise ukugeleza kwegazi emithanjeni lapho igazi lizokhishwa khona. Ingalo ingase ihlanzwe ngoketshezi olubulala amagciwane noma isulwe ngaphambi kokuba inaliti ifakwe. Khona-ke, igazi likhishwa engalweni kusetshenziswa umjovo futhi ligcinwe ebhodleleni. Isampula yegazi lithunyelwa ukuze liphinde lihlolwe elabhorethri.

Isho ukuthini Imiphumela Yokuhlola I-Ferritin (uma iphansi futhi iphakeme kunamazinga avamile)?

Ukuhlolwa kwe-ferritin kungase kuhlinzekwe ngesilinganiso sereferensi, esingase sihluke kulabhorethri eyodwa kuya kwenye. Uhlu lwabo lwereferensi lungase lubonise izinga elivamile le-ferritin okulindeleke ukuthi libe khona kumuntu onobulili obufanayo, ubudala, kanye nempilo jikelele jikelele. Njengomthetho ojwayelekile wesithupha, i-ferritin itholakala ngamanani aphezulu kubantu abadala asebekhulile, kwabesilisa, nakulabo abathatha izinto zokuvimbela inzalo ngomlomo. Ngakho-ke, ukuhlolwa kwe-ferritin kungase kuchazwe kangcono udokotela ongacacisa ukuthi kusho ukuthini kumuntu othile.

Imiphumela yokuhlolwa kwe-ferritin inikezwa nge-ng/ml. Amazinga e-ferritin, ajwayelekile kwabesilisa nabesifazane, anikezwe ngezansi ukuze kubhekwe kuwo.

• Abesilisa: 14.7 - 205.1 ng/ml
• Abesifazane: 30.3 kuya ku-565.7 ng/ml

Amazinga we-Ferritin aphansi

Kusukela ekuhlolweni, izinga le-ferritin eliphansi lisho ukuthi kukhona ukushoda kwe-iron noma i-ferritin, okubonisa ukugcinwa okuncane kwe-iron egazini. Esimeni sokuqala sokuntuleka kwe-iron anemia, kungase kube nesimo se-ferritin ephansi ne-iron evamile, ngenxa yaso umzimba ungase ukwazi ukwenza amangqamuzana egazi abomvu anempilo anele. Kungase kube nezimpawu ezimbalwa noma zingabikho nhlobo ze-anemia kulesi sigaba. Lapho ukuntuleka kwe-iron kuqhubeka, kungase kube nenani eliphansi le-ferritin elilandelwa amazinga ensimbi aphansi njengoba umzimba usebenzisa insimbi egciniwe emzimbeni. Kulesi sigaba, izimpawu zingase ziqale ukuvela. Ngakho, udokotela angase afune ukwenza ukuhlola okwengeziwe ukuze aqinisekise noma athole ubucayi be-anemia yokuntuleka kwensimbi.

Amazinga aphezulu we-Ferritin

Amazinga e-iron aphakeme angase abangele i-hemochromatosis, lapho umzimba udonsa i-iron eningi kunaleyo edingekayo, okubangele ukugcwala kwe-iron. Ukwengeza, esimweni sokuvuvukala, amazinga e-ferritin angase abe phezulu njengoba ewuphawu olubalulekile lokuvuvukala. Kungase kube nezinye izizathu zokwanda kwamazinga e-ferritin, njenge:

• Utshwala usebenzisa ukuphazamiseka
• Ukukhuluphala
• I-anemia ayibangelwa ukushoda kwensimbi
• Isifo sesibindi, kuhlanganise ne-Cirrhosis
• Hyperthyroidism
• Isifo sika-Adult-start Still
• Cancer

Isiphetho

Ukuhlolwa kwe-Ferritin kusiza ukuhlonza noma ukuqapha izimo ezihlukahlukene ezihlotshaniswa nokuntuleka noma ukugcwala kwe-iron egazini. Ukuhlola okunembile okuza wusizo ekuthathweni kwe-iron egazini inqobo nje uma usondela esikhungweni sezempilo esiphezulu njenge-CARE Hospitals.

Xhumana nathi namuhla ukuze uthole olunye usizo lwezokwelapha.

Imibuzo Evame Ukubuzwa

Q1. Liyini izinga elijwayelekile lokuhlolwa kwe-ferritin?

Izinga elivamile le-ferritin inani elivamile le-ferritin elikhona egazini ngokuphathelene neminyaka yomuntu, ubulili, kanye nempilo iyonke. Yethulwa kububanzi futhi ikalwa ngo-ng/ml. Kwabesilisa, isukela phakathi kuka-14.7 - 205.1 ng/ml, kuyilapho abesifazane bene-ferritin enobubanzi obungu-30.3 kuya ku-565.7 ng/ml.

Q2. Kwenzekani uma ukuhlolwa kwe-ferritin ku-positive?

Uma kukhona izinga eliphezulu le-ferritin, njengoba litholakala ekuhlolweni kwe-ferritin, libonisa ukuvuvukala. Izifo zesibindi, i-rheumatoid arthritis, kanye ne-hyperthyroidism ziphakathi kwezimbangela ezivamile zamazinga aphezulu e-ferritin ngenxa yokuvuvukala.

Q3. Kwenzekani uma ukuhlolwa kwe-ferritin kungenayo?

Amazinga aphansi e-ferritin angase abe inkomba yezinga lensimbi eliphansi njenge-anemia.

Q4. Ingabe i-hemoglobin ne-ferritin ziyefana?

I-Hemoglobin ne-ferritin womabili amaprotheni agcina insimbi, kodwa ngamanani ahlukene. Insimbi eningi igcinwa ku-hemoglobin, futhi cishe ingxenye eyodwa kwezine kuphela yobuningi igcinwa ku-ferritin.

Q5. Ngingalinyusa kanjani izinga lami le-ferritin?

Indlela engcono kakhulu yokukhulisa amazinga e-ferritin ukudla ukudla okune-iron, ikakhulukazi emithonjeni yezilwane.