Emkhakheni wokuxilongwa kwezokwelapha, ukuhlolwa kwe-HLA B27 kudlala indima ebalulekile ekwembuleni isixhumanisi sofuzo sokuphazamiseka kwe-autoimmune. Lokhu kuhlola kuvumela odokotela ukuthi banqume ubukhona bohlobo oluthile oluhlukile, olubuye lwaziwe nge-HLA B27, oluhlotshaniswa nezimo ezihlukahlukene ze-autoimmune. Ngokuqonda ukubaluleka kokuhlolwa kwe-HLA B27, abantu ngabanye bangathola imininingwane ebalulekile ngempilo yabo futhi bathole ukungenelela kusenesikhathi uma kunesidingo.

Kuyini ukuhlolwa kwe-HLA B27?

Ukuhlolwa kwe-HLA B27 ukuhlolwa kwezokwelapha okuhlonza ukuba khona kokuhluka kofuzo lwe-HLA B27 ku-DNA yomuntu. I-HLA imele i-Human Leukocyte Antigen, iqoqo lamaprotheni akhona ebusweni bamangqamuzana amhlophe egazi asiza amasosha omzimba ukukhomba futhi ahlukanise phakathi kwamangqamuzana angowawo nawangaphandle. Ukuba khona kwalesi sakhi sofuzo kuhlotshaniswa ne-autoimmune eminingana izifo.

Inhloso yokuhlolwa kwe-HLA B27

• Injongo eyinhloko yokuhlolwa kwe-HLA B27 iwukubona ubukhona bofuzo oluhlukile lwe-HLA B27 kukwakheka komuntu ngamunye. Lolu lwazi lubalulekile ngoba isakhi sofuzo se-HLA B27 sihlotshaniswe kakhulu nezinkinga ezimbalwa ze-autoimmune, okuhlanganisa i-ankylosing spondylitis, esebenzayo. sokuqaqamba kwamalunga, kanye ne-psoriatic arthritis. Ngokuthola ukuba khona kwalokhu kwehluka kofuzo, odokotela bangakuqonda kangcono ukuthambekela kwesiguli kulezi zimo futhi balungise ukwelashwa ngokufanele. 
• Qinisekisa ukuxilongwa lapho izimpawu zomtholampilo nokunye ukuhlola kungahlanganisi.
• Lokhu kuhlola kusiza ukuqinisa ubungozi bokuthola izifo ezizimele kubantu abanomlando womndeni noma ezinye izici eziyingozi.
• Usizo ekuqondiseni izinqumo zokwelashwa namasu okuphatha eziguli ezinemiphumela emihle ye-HLA B27.
• Siza ekuhlonzeni abantu abangase bazuze ekungeneleleni kusenesikhathi noma ekuqashweni eduze ngenxa yesimo sabo sofuzo.

Kudingeka nini Ukuhlolwa kwe-HLA B27?

Odokotela ngokuvamile batusa ukuhlolwa kwe-HLA B27 lapho umuntu eveza izimpawu ezihambisana nokuphazamiseka kwe-autoimmune okuhlotshaniswa nokuhluka kofuzo lwe-HLA B27. Lezi zimpawu zingase zihlanganise ukuphikelela ubuhlungu bamalunga, ukuqina, ukuvuvukala, noma ezinye izimpawu zezimo ze-autoimmune. 
Abantu abanomlando womndeni wezifo ezihlobene ne-HLA B27 bangase futhi belulekwe ukuthi bahlole lokhu kuhlolwa njengesinyathelo sokuqala.
Odokotela bangase benze ukuhlola kwe-HLA-B27 ngezikhathi ezithile ukuze baqaphe ukuqhubeka kwesifo futhi bahlole ukusebenza kahle kokwelashwa kubantu abane-spondyloarthropathies eyaziwayo. 

Kwenzekani Ngesikhathi Sokuhlolwa kwe-HLA B27?

Inqubo yokuhlola i-HLA B27 ibandakanya lezi zinyathelo ezilandelayo:

• Ukuqoqwa kwesampula yegazi: Ngesikhathi sokuhlolwa kwe-HLA B27, udokotela uzokhipha isampula yegazi elincane kumuntu futhi alithumele elabhorethri lapho kusetshenziswa khona izindlela ezikhethekile ukuze kuhlonzwe ukuba khona kokuhluka kofuzo lwe-HLA B27. 
• Ucwaningo lwaselabhorethri: Kulebhu, uchwepheshe ukhipha i-DNA kusampula yegazi futhi aqondise ngokusobala isakhi sofuzo se-HLA B27 ukuze sitholwe. Uma ukuhlaziya sekuqediwe, ilabhorethri izohlinzeka ngombiko obonisa ukuthi ukwahluka kofuzo lwe-HLA B27 kukhona noma akukho.
• Ukuhumusha kombiko: Udokotela utolika imiphumela yokuhlolwa kwe-HLA-B27 kumongo womlando wezokwelapha womuntu ngamunye, izimpawu, nokunye ukuhlola kokuxilonga. Baxoxa ngemiphumela yemiphumela nomuntu futhi bangase batuse izinyathelo zokuxilonga ezengeziwe noma izindlela zokwelapha ezisekelwe kulokho okutholakele.

Isho Ukuthini Imiphumela Yokuhlolwa kwe-HLA B27?

Lapho utolika imiphumela yokuhlolwa kwe-HLA B27, ukubonisana nodokotela onganikeza ukuhlaziya okuphelele kubalulekile. Uma ukuhlolwa kubonisa izinga eliphansi noma ukungabikho kokuhluka kofuzo lwe-HLA B27, ngokuvamile kuphakamisa ubungozi obuphansi bokuthuthukisa ukuphazamiseka kwe-autoimmune okuhlobene ne-HLA B27. Ngakolunye uhlangothi, uma ukuhlolwa kukhombisa izinga eliphezulu kunelivamile lokuhluka kofuzo lwe-HLA B27, kungase kubonise ukwanda kokuthambekela kulezi zimo. Kodwa-ke, kubalulekile ukuqaphela ukuthi umphumela omuhle we-HLA B27 awuqinisekisi ukuthuthukiswa kwe-autoimmune. disorder.

Isho Ukuthini Imiphumela Engavamile

Imiphumela yokuhlolwa kwegazi ye-HLA B27 engavamile ingase ibonise ingozi engaba khona yokuthuthukisa ukuphazamiseka kwe-autoimmune okuhlobene ne-HLA B27. Kubalulekile ukukhumbula ukuthi imiphumela engajwayelekile ayikona ukuxilonga okuqinisekile kodwa iwucezu lolwazi okufanele lucatshangelwe kanye nokunye okutholwe emitholampilo. Uma imiphumela engavamile ikhona, kungase kudingeke ukuhlolwa okwengeziwe kwezokwelapha ukuze kunqunywe inkambo efanele yesenzo. Odokotela bazocabangela izimpawu zomuntu ngamunye, umlando wezokwelapha, kanye nezivivinyo ezengeziwe zokuxilonga ukuze bakhe ukuxilonga okunembile futhi balungise uhlelo lokwelapha olusebenzayo lwe-HLA B27.

Isiphetho

Ukuhlolwa kwegazi kwe-HLA B27 kusebenza njengokuhlola okubalulekile, okuhlinzeka ngemininingwane ngesixhumanisi sofuzo sezinkinga ze-autoimmune. Ngokuthola ukuba khona kokuhluka kofuzo lwe-HLA B27, odokotela bangaqonda kangcono ukuthambekela komuntu ezimweni ezihambisana ne-HLA B27 futhi bathunge ukwelashwa ngendlela efanele. Kodwa-ke, kubalulekile ukukhumbula ukuthi ukuhlolwa okuhle kwe-HLA B27 akuqinisekisi ukukhula kokuphazamiseka kwe-autoimmune. Uma unokukhathazeka ngezimo ze-autoimmune noma umlando womndeni wezifo ezihlobene ne-HLA B27, funa isiqondiso kudokotela ongakuqondisa ezinqubweni ezifanele zokuxilonga nezokwelashwa.

FAQ sika

1. Liyini Izinga Elijwayelekile Lokuhlolwa Kwe-HLA B27?

Izinga elijwayelekile lokuhlolwa kwe-HLA B27 libonisa ukungabikho noma izinga eliphansi lokuhluka kofuzo lwe-HLA B27. Ngokuvamile iphakamisa ubungozi obuphansi bokuthuthukisa ukuphazamiseka kwe-autoimmune okuhlobene ne-HLA B27.

2. Kwenzekani uma ukuhlolwa kwe-HLA B27 Kuhle?

Uma ukuhlolwa kwe-HLA B27 ku-positive, kubonisa ukuba khona kokuhluka kofuzo lwe-HLA B27. Nakuba umphumela omuhle ungase uphakamise ukuthambekela okukhuphukile ku-HLA B27-associated autoimmune disorders, akuqinisekisi ukuthuthukiswa kwalezi zimo. Ukuhlolwa okwengeziwe kwezokwelapha kuyadingeka ukuze kunqunywe inkambo efanele yesenzo.

3. Kwenzekani uma ukuhlolwa kwe-HLA B27 Kubi?

Ukuhlola okunegethivu kwe-HLA B27 kubonisa ukungabikho kokuhluka kofuzo lwe-HLA B27. Ngokuvamile iphakamisa ubungozi obuphansi bokuthuthukisa izimo ze-autoimmune ezihambisana ne-HLA B27. Kodwa-ke, kubalulekile ukukhumbula ukuthi ezinye izici zingase zibe nomthelela ekuthuthukiseni izimo ze-autoimmune, futhi ukuhlolwa okwengeziwe kungase kudingeke uma izimpawu ziqhubeka.

4. Imaphi Amapharamitha Akalwa Ekuhlolweni kwe-HLA B27?

Ukuhlolwa kwe-HLA B27 kulinganisa ngokusobala ubukhona noma ukungabikho kofuzo oluhlukile lwe-HLA B27 ku-DNA yomuntu. Ukuhlola kugxile ekuhlonzeni ukulandelana kofuzo okuthile okuhlotshaniswa nofuzo lwe-HLA B27.

5. Kuthatha Isikhathi Eside kangakanani Ukuhlolwa kwe-HLA B27?

Ukuhlolwa kwe-HLA B27 kuyinqubo esheshayo evamise ukuthatha imizuzu eyi-15 ukuya kwengama-30 ukuqeda. Kodwa-ke, isikhathi esiphelele singahluka futhi sincike ezintweni ezifana nomthwalo welabhorethri kanye nesampula yezinto zokuhamba.