Odokotela basebenzisa ukuhlolwa kwe-hsCRP ukuze bathole isifo senhliziyo kanye nezingozi zohlangothi ngisho nalapho amazinga e-cholesterol ebonakala evamile. Lolu phawu oluncane kodwa olunamandla lokuvuvukala luwuhlelo olubalulekile lokuxwayisa ngesifo senhliziyo nemithambo yegazi. Odokotela bangabona izinkinga ngaphambi kokuba izivivinyo zendabuko zizithole.

Ukuhlolwa kwe-High-Sensitivity C-reactive Protein (HsCRP protein) kungathola amanani amancane okuvuvukala emithanjeni yegazi lapho ukuhlolwa okujwayelekile kugeje. Ukuhlola okujwayelekile kwe-CRP kuthola amazinga asuka ku-3 mg/L, kodwa inguqulo ezwela kakhulu ikhomba ukunyuka okucashile phakathi kuka-1 no-3 mg/L. Lokhu kwanda okuncane kuvame ukubonisa ukuqala kwezinkinga ezihlobene nenhliziyo okungenzeka zinganakwa ngenye indlela. 

Ucwaningo lubonisa ukuthi iziguli ezinamazinga aphezulu e-HsCRP zinengozi ephindwe izikhathi ezingu-1.5 enkulu yezehlakalo ezinkulu zenhliziyo uma kuqhathaniswa nalezo ezinokufundwa okuphansi kakhulu. Lokhu kuhlala kuyiqiniso ngisho nangemva kokucabangela ezinye izici eziyingozi. Ukuhlolwa futhi kusiza odokotela ukuthi babone ukuthi yiziphi iziguli ezidinga ukwelashwa kokuvimbela ngaphandle kokuthi "zivamile" cholesterol amaphrofayili. Ukufunda ngokuhlolwa kwe-HsCRP nezigaba ezijwayelekile kukunikeza isithombe esigcwele sezingozi zempilo yenhliziyo yakho.

Kuyini ukuhlolwa kwe-High Sensitivity CRP (C-reactive Protein)?

Isibindi sakho senza i-CRP lapho ukuvuvukala kwenzeka emzimbeni wakho. Ukuhlolwa okujwayelekile kwe-CRP kanye ne-HsCRP kuhlukile ekuzweleni kwakho. Ukuhlola okujwayelekile kuthola amazinga aphezulu okuvuvukala, kuyilapho inguqulo ezwela kakhulu ingabona izinguquko zamaminithi phakathi kwebanga elivamile le-CRP elingeke liqashelwe. Lokhu kuzwela okuthuthukisiwe kwenza kube usizo, ikakhulukazi uma kufanele uhlole Isifo senhliziyo engozini ngisho noma ezinye izinkomba zibukeka zijwayelekile.

Kufanele Uthole Nini Ukuhlolwa kwe-HsCRP?

Ukuhlolwa kwe-HsCRP kusebenza kahle kakhulu uma unengozi emaphakathi yokuhlaselwa yinhliziyo - amathuba angu-10-20% okuba nokukodwa eminyakeni eyishumi ezayo. Udokotela wakho angancoma lokhu kuhlolwa uma:

• Yiba nesifo senhliziyo emlandweni womndeni wakho
• Khuluma ne-cholesterol ephezulu, nomfutho wegazi ophezulu, noma sikashukela
• Ukhuluphele
• Indlela yokuphila yama-sedentary
• Qhubeka ubheme

I-American Heart Association kanye ne-CDC bathi akuwona wonke umuntu odinga ukuhlolwa kwe-HsCRP. Kodwa ukuhlolwa kunikeza imininingwane ebalulekile nokunye ukuhlola kwengozi, ikakhulukazi uma une-cholesterol ye-LDL engaphansi kuka-130 mg/L.

Kungani Ngidinga Ukuhlolwa Kwe-CRP Okuzwela Kakhulu?

Umzimba wakho ungase ufihle ukuvuvukala okusongela impilo yenhliziyo yakho, ngisho nokufundwa okuhle kwe-cholesterol. Ucwaningo lubonisa ukuthi ukuvuvukala okuqhubekayo kwezinga eliphansi kudlala indima enkulu ekwelashweni kwe-atherosclerosis - imithambo yegazi iba mincane emafutheni.

Ukuhlolwa kwe-HSCRP kusiza ukuthola lolu songo olufihliwe. Ucwaningo lubonisa ukuthi abantu abanamanani aphezulu e-HsCRP babhekana nengozi ephindwe ka-1.5 kuya kwezine yokuhlaselwa yinhliziyo kunalabo abanokufundwa okuphansi, ngisho ne-cholesterol evamile.

Lokhu kuhlola futhi kusiza ukulandelela ukuthi ukwelashwa kusebenza kahle kangakanani. Amazinga e-CRP kufanele ehle njengoba ukuvuvukala kwehla - lokhu kukhombisa ukuthi uhlelo lwakho lokwelapha luyasebenza.

Inqubo yokuhlolwa kwe-HsCRP

Udokotela oqeqeshiwe noma i-phlebotomist uzodonsa igazi lakho ukuze enze ukuhlolwa kwe-HsCRP. Inqubo inalezi zinyathelo:

• Hlanza futhi ubulale amagciwane ingxenye engaphakathi yengalo yakho
• Faka inaliti encane emthanjeni (imvamisa eduze kwendololwane yakho)
• Qoqa igazi eshubhuni lokuhlola
• Cindezela ukotini noma i-gauze ukumisa ukopha
• Faka ibhandishi lapho

Uzokwenziwa ngaphansi kwemizuzu emihlanu. Isampula yegazi lakho liya elebhu lapho imishini ekhethekile ikala inani eliqondile le-CRP egazini lakho.

Uzilungiselela Kanjani Ukuhlolwa kwe-HsCRP?

Ngokuvamile awudingi ukulungiswa okukhethekile kokuhlolwa kwe-HSCRP. Kodwa ezinye izinto zingashintsha imiphumela yakho:

• Yeqa ukuvivinya umzimba okuqinile njengezisindo ezinzima noma ama-run amade ngaphambi kokuhlolwa
• Tshela udokotela wakho ngazo zonke izithasiselo zakho nemithi
• Kungase kudingeke ukuthi uzile ukudla ubusuku bonke uma uthola ezinye izivivinyo ezifana nokuhlolwa kwe-cholesterol

Hlela ukuhlolwa kwakho uma ungenazo izifo zakamuva, ukulimala, noma izifo ezingase zikhuphule amazinga okuvuvukala okwesikhashana.

Isho Ukuthini Imiphumela Engavamile

Ububanzi belebhu bungase buhluke kancane, kodwa ngokuvamile:

• Ingozi ephansi: ngaphansi kuka-1.0 mg/L
• Ingozi emaphakathi: 1.0 kuya ku-3.0 mg/L
• Ingozi ephezulu: ngaphezu kuka-3.0 mg/L

Imiphumela ephakathi kuka-1.0 no-10.0 mg/dL ingase ikhombe ezimweni ezifana nalezi rheumatoid arthritis, isifo senhliziyo, i-pancreatitis, noma i-bronchitis. 

Ukufundwa okungaphezu kuka-10 mg/dL kuphakamisa ukuvuvukala okungathi sína, okuvame ukuxhunyaniswa nezifo ezibangelwa amagciwane noma ezibangelwa amagciwane, noma ukulimala okukhulu. 

Amanani angaphezu kuka-50 mg/dL abonisa ukuvuvukala okukhulu okuhlangana nezifo ezibangelwa amagciwane cishe izikhathi ezingama-90%.

Qaphela ukuthi ukufunda okuphezulu akusho ngaso sonke isikhathi ukuthi unesifo senhliziyo. Ukuhlolwa kwe-HsCRP akubonisi ukuthi ukuvuvukala kuvela kuphi, ngakho odokotela babheka imiphumela yakho kanye nezinye izindlela zempilo nezici eziyingozi.

Isiphetho

Indima yokuvuvukala esifweni senhliziyo iyimpumelelo ebalulekile ekuvimbeleni isifo senhliziyo. Ukuhlolwa kwe-HSCRP kuyindlela enhle yokuthola ulwazi mayelana nezingozi ezifihliwe zenhliziyo nemithambo yegazi okungenzeka ukuthi ukuhlolwa okujwayelekile kwe-cholesterol kungase kugeje. Amazinga akho e-cholesterol angase abukeke enempilo, kodwa ukuvuvukala kusengalimaza buthule imithambo yegazi.

Lokhu kuhlolwa kwegazi kunikeza imiphumela enamandla, ikakhulukazi uma unomlando womndeni wezinkinga zenhliziyo noma izici eziyingozi zendlela yokuphila. Odokotela abayincomi kuwo wonke umuntu kodwa ukuhlolwa kunikeza ulwazi olubalulekile uma uwela ezigabeni ezimaphakathi zengcuphe.

Impilo yenhliziyo yakho idinga indlela yokuhlola ephelele. Ukubheka ngale kwezinombolo ze-cholesterol nokwengeza izimpawu zokuvuvukala njenge-HsCRP kwakha isithombe esingcono sempilo yenhliziyo nemithambo yegazi. Kufanele ukhulume nodokotela wakho ngalokhu kuhlolwa uma ukuhlaselwa yinhliziyo noma unhlangothi usengozini. Ukutholwa kusenesikhathi kukunikeza ithuba elingcono kakhulu lokuvimbela izehlakalo ezibucayi zenhliziyo esikhathini esizayo.

Imibuzo Evame Ukubuzwa

1. Kwenzekani uma i-HsCRP iphezulu?

Umzimba wakho ukhombisa ukwanda kokuvuvukala lapho amazinga e-HsCRP enyuka. Lokhu kungasho ukuthi:

• Ingozi ephezulu yenhliziyo nemithambo yegazi - Ngisho ne-cholesterol evamile, ukufundwa okuphezulu kusho ukuthi unethuba eliphezulu lokuyikhipha isifo senhliziyo noma unhlangothi
• Izimo zezempilo ezifana nokuphazamiseka kwe-autoimmune, izifo, noma isifo senhliziyo kungaba yisizathu
• Ukulimala kwemithambo yegazi kungenzeka ngaphandle kokuthi uqaphele noma yiziphi izimpawu

Ukufundwa okuphezulu akusho ngaso sonke isikhathi okuthile okungathí sina, kodwa udokotela wakho kufanele akuhlole.

2. Kwenzekani uma i-HsCRP iphansi?

Izindaba ezinhle! I-HsCRP ephansi (ngaphansi kuka-1 mg/L) ngokuvamile isho ukuthi unokuvuvukala okuncane. Lokhu kuyasitshela:

• Ingozi yakho yenhliziyo nemithambo yegazi iphansi kunabantu abanokufundwa okuphezulu
• Imithambo yakho yegazi iphilile futhi ayinamonakalo omncane wokuvuvukala
• Ukwelashwa kwakho kuyasebenza uma ubusebenzisa imithi noma izinguquko endleleni yokuphila ukuze ulwe nokuvuvukala

Amanani aphansi angcono uma kuziwa ku-HsCRP - awukwazi ukuba namaleveli aphansi kakhulu.

3. Liyini izinga elijwayelekile le-HsCRP?

Odokotela babheka amazinga e-HsCRP ngale ndlela:

• Ingozi ephansi: Ngaphansi kuka-1.0 mg/L
• Ingozi emaphakathi: Phakathi kuka-1.0-3.0 mg/L
• Ingozi ephezulu: Ngaphezu kuka-3.0 mg/L

Abantu abadala abaningi abanempilo bahlala ngaphansi kuka-0.9 mg/dL.

4. Ithini inkomba yokuhlolwa kwe-HsCRP?

Udokotela wakho angase ancome ukuhlolwa kwe-HsCRP ku:

• Hlola ingozi yokuhlaselwa yinhliziyo uma usengozini emaphakathi yenhliziyo 
• Landelela izimo ezivuvukalayo njenge-arthritis ye-rheumatoid
• Bona ingozi yakho yokuba nesinye isifo senhliziyo
• Bheka ukuvuvukala lapho ezinye izinto eziyingozi zikhona kodwa i-cholesterol ibukeka ijwayelekile

5. Yikuphi ukutheleleka okubangela i-CRP ephezulu?

Lezi zifo zingakhuphula amazinga e-CRP kakhulu:

• Ukutheleleka kwamagciwane, ikakhulukazi inyumoniya
• Izifo zokuphefumula ezibangelwa amagciwane ezihlanganisa i-adenovirus kanye nomkhuhlane
• I-Sepsis kanye nezinye izifo ezinzima zebhaktheriya
• Ukutheleleka nge-COVID-19, lapho i-CRP ephezulu ixhumene nezinkinga

6. Liyini izinga elethusayo le-CRP?

Udinga ukunakwa uma amazinga eba ngaphezu kuka-10 mg/dL. Nakhu okunye okumele ukwazi:

• Ukufundwa okungaphezu kuka-50 mg/dL kupela ingozi futhi kuhlotshaniswa nezifo ezibangelwa amagciwane 90% wesikhathi
• Amanani aphakathi kuka-1-10 mg/dL angase akhombe ezimweni ezingapheli

7. Yini okufanele uyenze uma i-HsCRP iphezulu?

Thatha lezi zinyathelo uma i-HsCRP yakho iphezulu:

• Bonana nodokotela wakho ukuze ahlolwe futhi ngokunokwenzeka athathe ukuhlolwa okwengeziwe
• Sebenza empilweni yenhliziyo ngokuzivocavoca, ukulawula isisindo, nokulawula umfutho wegazi
• Khuluma nodokotela wakho ngemithi efana nama-statins
• Yekani ukubhema ngoba inyusa amazinga okuvuvukala ngokuningi
• Yehlisa ukuphuza utshwala ube ngamanani aphakathi

8. Yini okufanele ngidle uma i-hsCRP yami iphezulu?

Ukudla okufanele kungasiza ukwehlisa amazinga akho e-HsCRP:

• Yidla ukudla okune-omega-3 okuningi njenge-salmon nezinhlanzi ezinamafutha
• Khetha amaprotheni ezitshalo nezithelo nemifino emisha
• Gwema ukudla okugayiwe, ama-carbohydrate acolisisiwe kanye nokudla okuthosiwe
• Sebenzisa izinongo ezifana ne-turmeric ne-ginger ezilwa nokuvuvukala
• Faka imifino enamaqabunga, amantongomane, nezinhlamvu eziphelele ekudleni kwakho njengoba kusiza ukunciphisa izimpawu zokuvuvukala