I-MCH imele i-Mean Corpuscular Haemoglobin, okuyiphrotheni esiza ekulethweni komoyampilo kuwo wonke umzimba. Ukuhlolwa kwe-MCH ukuhlolwa kwegazi okuxilonga okusetshenziselwa ukuhlola impilo yonke yomuntu ngokukala amazinga e-MCH egazini. 

Nakuba ukuhlolwa kwegazi kwe-MCH kanye ne-MCHC (Mean Corpuscular Hemoglobin Concentration) kuyizivivinyo ezimbili ze-serological ezinencazelo efanayo yamazinga azo emzimbeni, okubonisa ukuthi impilo ye-hemoglobin egazini, kokubili akufani. Nakuba izinga le-MCH libhekisela ku-hemoglobin kungqamuzana ngalinye elibomvu legazi, i-MCHC isisindo esimaphakathi saleyo hemoglobin esekelwe kumthamo wamangqamuzana abomvu egazi.

Kuyini ukuhlolwa kwegazi kwe-MCH? 

Ukuhlolwa kwegazi kwe-MCH ukuhlolwa kokuxilonga okutuswa umhlinzeki wezempilo, okwenziwa njengengxenye yokuhlolwa kwegazi okubizwa ngokuthi i- complete blood count (CBC). Ukuhlolwa kwe-CBC kuhlola ukwakheka kwegazi, kubheka inani lamaseli abomvu egazi (RBCs), amaseli amhlophe egazi (WBCs), namaplatelet kusampula yegazi. Ukuhlolwa kwe-CBC kusiza ukunikeza umbono jikelele wempilo yomuntu jikelele.

Amazinga e-MCH egazini akalwa ngama-piccograms (pg). Ibanga elijwayelekile lamazinga e-MCH ekuhlolweni kwegazi kwe-MCH lisukela phakathi kuka-26 kuya ku-33 pg we-hemoglobin ngeseli elibomvu legazi kubantu abadala.

Inhloso yokuhlolwa kwegazi kwe-MCH

Ukuhlolwa kwegazi kwe-MCH kusiza ukunquma isilinganiso senani le-hemoglobin equkethwe egazini. Akukalwa ngokuqondile; I-MCH isekelwe ezingeni le-hemoglobin (Hg), elimelela inani eliphelele le-hemoglobin ekhona egazini. Izinga le-MCH, njengoba likalwa ukuhlolwa kwe-CBC, lingasiza ekuboneni uhla lwezinkinga emzimbeni, ezihluka ezimeni zokuntula izakhi (ezifana ne i-anemia) ezimeni ezingamahlalakhona emzimbeni.

I-MCH yenziwa kanjani?

Ukuhlolwa kwegazi kwe-MCH kungase kwenziwe njengengxenye yokuhlolwa kwegazi okuphelele. Isazi se-phlebotomist singase siqoqe isampula legazi, elibese lihlolwa elabhorethri ngokusekelwe kumingcele yalo. Ukuze ubale izinga le-MCH, inani le-hemoglobin lihlukaniswa ngesibalo se-RBC. Lesi sibalo siveza isilinganiso senani le-hemoglobin ngengqamuzana ngalinye elibomvu legazi. 

Asho ukuthini amazinga aphezulu e-MCH?

Amazinga e-MCH angaphezu kuka-34 pg ekuhlolweni kwegazi kwe-MCH angabhekwa aphezulu. Inani eliphakeme le-MCH ngokuvamile libangelwa i-macrocytic anemia, ukuphazamiseka kwegazi okuholela ekukhiqizweni kwamangqamuzana abomvu egazi ambalwa kunokuvamile. Ngenxa yalokho, amangqamuzana egazi abomvu makhulu kunokujwayelekile futhi athwala i-hemoglobin eyengeziwe kune-RBC evamile. Lesi simo sibangelwa a ukuntuleka kwevithamini B12 (noma i-folic acid) emzimbeni.

Udokotela ukuncoma nini ukuhlolwa kwe-MCH?

Udokotela angase atuse ukuhlolwa kwe-MCH ngesikhathi sokuhlolwa okujwayelekile noma ukuhlola inkinga ethile yezempilo ehlobene nesifo segazi, esifana ne-anemia.

Yiziphi izimpawu ze-High MCH Levels?

Abantu abahlushwa i-macrocytic anemia bangase babe nezimpawu eziba zimbi kakhulu ngokuhamba kwesikhathi. Lezi zimpawu zingabandakanya:

• Ukukhathala
• Ukuphaphatheka kwesikhumba
• Ukushaya kwenhliziyo okusheshayo
• Izipikili eziphukile
•  Ukuhlushwa okumpofu
•  Ukudideka nokulahlekelwa inkumbulo

Kungase kube nezimpawu ezengeziwe zamazinga aphezulu e-MCH egazini, njenge:

• Ukudabuka noma ukuhlanza
• Ukuvimbela
• Uhudo
• Ukuthukuthela
• Ukuncipha kwesifiso sokudla
• Ukuba nomuzwa wokuntweza ezandleni nasezinyaweni
• Ubushelelezi noma ukuzwela olimini

Imiphumela ye-MCH & Ububanzi Obujwayelekile 

Ukuze utolike amazinga e-MCH kusampula ngendlela efanele, imiphumela idinga ukuqhathaniswa nohlu olunikeziwe lwereferensi lokuhlolwa kwaselabhorethri. Amazinga e-MCH akalwa ngama-picograms (pg). Uma inani le-MCH liwela ngaphandle kwebanga lesithenjwa elinikeziwe, lingabonisa ukuthi inani le-hemoglobin kuma-RBC liphansi kakhulu noma liphezulu kakhulu. Ngezinye izikhathi, ngisho noma izinga le-MCH liwela ngaphakathi kwalolu hlu, kusengaba khona isimo sezempilo esicashile esingatholakala ngosizo oluvela emiphumeleni yezinye izinkomba zokuhlolwa kwegazi.

Nakuba amalabhorethri ahlukene angase abe nemingcele ehlukene yokulinganisa amazinga e-MCH pg ekuhlolweni kwegazi, izinga elivamile le-MCH livamise ukuba phakathi kwama-picogram angu-26 nama-33. Ububanzi bereferensi nobubanzi obungavamile bunikezwe ngezansi ukuze kuqhathaniswe. 

Yini engabangela amazinga aphezulu e-MCH?

Izinga eliphezulu le-MCH ngokuvamile libangelwa ukushoda kwe-vitamin B12. Kungase futhi kube nezinye izimbangela zamazinga aphezulu e-MCH, ezingafaka lezi zimo ezilandelayo:

• Izifo zesibindi
• Ukusebenza ngokweqile kwendlala yegilo
• Ukuphuza utshwala njalo
• Ukusetshenziswa njalo kwemithi ye-estrogen
• Izinkinga zokutheleleka kanye/noma umdlavuza

Yini okufanele ngiyenze uma nginezinga eliphezulu le-MCH?

Amazinga aphezulu e-MCH egazini, ngenxa ye-macrocytic anemia noma ezinye izimo ezingaphansi, angase aphathwe ngendlela ehlukile ezigulini ezihlukene ngokusekelwe ezimpawu zazo kanye nobukhulu besimo. Ukungeza okwengeziwe vitamin B12 ekudleni kungasiza ukuthuthukisa lesi simo. Lokhu kungenziwa ngokudla ukudla okufana nenhlanzi, isibindi, imifino enamahlamvu aluhlaza, kanye nezinhlamvu eziqinisiwe. Lokhu kunomthelela ekwenzeni ngcono ukukhiqizwa kwamangqamuzana abomvu egazi. Ezinye izimo ezinomthelela emazingeni aphezulu e-MCH zingelashwa ngezinyathelo ezifanele njengoba kunqunywe udokotela owelaphayo.

Isiphetho

I-Mean corpuscular hemoglobin iyinkomba yezempilo ebalulekile phakathi kwezinye izici. Kuvame ukukalwa ngesikhathi sokuhlolwa kwegazi okujwayelekile noma lapho udokotela esola ukuntuleka kwegazi emzimbeni ngokusekelwe ezimpawu zesiguli. Ukungalingani emazingeni e-MCH kungalawulwa ngokugcina ukudla okunempilo futhi kuhlanganise nemisoco edingekayo. Uhlelo olufanele lokudla lokululama lungaklanywa ngokubonisana no-a uchwepheshe wezokudla obhalisiwe. Ukuhlolwa kwegazi okuvamile kungaveza izinguquko noma ukuthuthukiswa kwezimo ezithinta iziguli ngenxa yokungalingani kwamazinga e-MCH emizimbeni yazo.

Imibuzo Evame Ukubuzwa

1. Kusho ukuthini amazinga aphansi e-MCH ekuhlolweni kwegazi?

Izimpendulo. Amazinga e-MCH angaphansi kwama-picogram angama-26 angabhekwa njengaphansi futhi angase abe ngenxa yezizathu eziningi ezihlobene namangqamuzana abomvu egazi njengokulahlekelwa igazi eliningi, ukuntuleka kwensimbi, kanye ne-microcytic anemia.

2. Ziyini izindleko zokuhlolwa kwe-MCH?

Izimpendulo. Ukuhlolwa kwe-MCH kwenziwa njengengxenye yokuhlolwa kwegazi okuphelele (CBC) futhi kungase kubize cishe ama-Rs. 70 kuya ku-Rs. 150.

Izikhombo:
https://www.medicalnewstoday.com/articles/318192#What-is-MCH
https://www.webmd.com/a-to-z-guides/what-are-mch-levels
https://www.testing.com/itests/mch-test/#:~:text=The%20MCH%20test%20 is%20 one,and%20issues%20in%20the%20body.