Ukuhlolwa kwegazi kwe-MCHC kudlala indima ebalulekile kunqubo yephaneli ye-Complete Blood Count (CBC) futhi kunikeza ulwazi olubalulekile mayelana nesimo sempilo yomuntu. Ukuhlolwa kwe-MCHC kulinganisa isilinganiso sokuhlushwa kwe-hemoglobin ekhona kumaseli abomvu egazi. I-Hemoglobin idlala indima ebalulekile ekuthuthweni komoya-mpilo kuwo wonke umzimba womuntu. 

Kuyini ukuhlolwa kwegazi kwe-MCHC?

Ukuhlolwa kweMean Corpuscular Hemoglobin Concentration (MCHC) kulinganisa isilinganiso senani le-hemoglobin ngengqamuzana ngalinye elibomvu legazi ngokuhlobene nevolumu yeseli. I-Hemoglobin iyiphrotheni etholakala kumangqamuzana abomvu egazi, futhi inesibopho sokuthutha umoya-mpilo kuwo wonke umzimba. I-Hemoglobin ibalulekile ekukhuleni nasekusebenzeni kwezitho nezicubu. Ukuhlolwa kwegazi kwe-MCHC kungasebenza njengesisekelo ukuxilongwa kwe-anemia futhi ziyingxenye yesibalo segazi eliphelele (CBC).

Inhloso yokuhlolwa kwegazi kwe-MCHC

IMean Corpuscular Hemoglobin Concentration (MCHC) ingelinye lamamethrikhi amaningi asetshenziselwa ukuhlola umsebenzi nempilo ye-RBC ukuze kutholwe izimpawu ze-anemia nezinye izifo zegazi. Ukuhlolwa kwe-MCHC kungase ku-odwe ngokuqondile ngumhlinzeki wezempilo uma isiguli:

• Uzwa izimpawu ze-anemia, njengokukhathala, isikhumba esiphaphathekile, noma isiyezi.
• Ihlolwa ngezimbangela ezihlukene ze-anemia.

Nakuba ukuhlolwa kwe-MCHC kubalulekile ekuxilongeni i-anemia, ngokuvamile kusetshenziswa kanye nenani lamaseli abomvu nezinye izinkomba zamaseli abomvu ukusiza ekuxilongweni kwezinye izimo zezempilo.

Ukusetshenziswa kokuhlolwa kwegazi kwe-MCHC

Ukuhlolwa kwegazi kweMean Corpuscular Hemoglobin Concentration (MCHC) kuyingxenye yesibalo segazi esiphelele (CBC) futhi kunikeza ulwazi mayelana nokugcwala kwe-hemoglobin kuvolumu enikeziwe yamangqamuzana abomvu egazi. Ukuhlolwa kwegazi kwe-MCHC kunokusetshenziswa okuningana okubalulekile:

• Ukuhlola I-Hemoglobin: Inhloso eyinhloko yokuhlolwa kwe-MCHC ukuhlola ukuhlushwa kwe-hemoglobin ngaphakathi kwamaseli abomvu egazi. I-Hemoglobin iyiphrotheni ethwala umoya-mpilo egazini, futhi ukuhlola ukugcwala kwawo kusiza ekuqondeni amandla okuthwala umoya-mpilo egazini.
• Ukuxilongwa Kwe-anemia: Amazinga e-MCHC abalulekile ekuxilongweni nasekuhlukaniseni i-anemia. I-anemia yisimo esibonakala ngenani elincishisiwe lamangqamuzana abomvu egazi noma ukugcwala kwe-hemoglobin ephansi, okuholela ezimpawu ezinjengokukhathala, ubuthakathaka, nokuphaphatheka. Ukuhlolwa kwe-MCHC kunomthelela ekunqumeni uhlobo nobukhulu be-anemia.
• Ukwehlukanisa Izinhlobo Ze-Anemia: Amazinga e-MCHC, kanye nezinye izinkomba zamangqamuzana egazi abomvu, asiza ekuhlukaniseni phakathi kwezinhlobo ezihlukahlukene ze-anemia. Isibonelo, ku-anemia yokuntuleka kwensimbi, amazinga e-MCHC angase abe phansi, kuyilapho ezimeni ezifana ne-hereditary spherocytosis, amazinga e-MCHC angase anyuswe.
• Ukuqapha Ukwelashwa: Kubantu abathola ukwelashwa kwe-anemia noma izimo ezihlobene, ukuhlola okuvamile kwe-MCHC kusiza ukuqapha ukusebenza kokungenelela, okufana nokwengezwa kwensimbi noma ezinye izindlela zokwelapha ezihloselwe ukubhekana nembangela ewumsuka.
• Ukuhlonza Ukuphazamiseka Kwegazi: Amazinga e-MCHC angajwayelekile angase abe inkomba yezinkinga ezithile ze-hematological. Amazinga e-MCHC aphezulu kakhulu noma aphansi angahlotshaniswa nezimo ezifana ne-thalassemia, i-hemoglobinopathies, noma ukuntuleka kwamavithamini.
• Ukuhlola Ngaphambi Kokuhlinzwa: Amazinga e-MCHC angase ahlolwe njengengxenye yokuhlolwa kwegazi ngaphambi kokuhlinzwa ukuze kuqinisekiswe ukuthi abantu abahlinzwayo banamandla aphelele okuthwala umoya-mpilo futhi babone noma iyiphi i-anemia engaphansi engathinta umphumela wokuhlinzwa.

Kwenziwa kanjani ukuhlolwa kwegazi kwe-MCHC?

Ukuhlolwa kwe-MCHC kubandakanya ukuqoqa igazi ngomthambo obhoboziwe endaweni ebonakalayo yengalo. Ngaphambi kokufaka inaliti, udokotela uzohlanza indawo. Ukudweba igazi kuthatha imizuzwana embalwa kuphela. Ngemva kwalokho, udokotela uzofaka ingcindezi endaweni yokusikwa ukuze avimbele ukopha. Uma isampula yegazi selitholakele, isiguli sizothola i-gauze nebhandeshi lokuvala indawo yokusikwa.

Asho ukuthini amazinga aphezulu okuhlolwa kwegazi e-MCHC?

Ukuba khona kwamazinga aphezulu okugcwala kwe-hemoglobin kunokujwayelekile kumangqamuzana abomvu egazi kungase kuboniswe ngokuhlolwa kwegazi kwe-MCHC emazingeni aphezulu. Abantu abadala abanamazinga e-MCHC aphakathi kuka-31 no-37 g/dL babhekwa njengokujwayelekile. Ngisho noma i-MCHC ephezulu emibikweni yegazi ngokwayo ingakhombisi ukuthi umuntu unezinkinga zempilo ezicashile, ingabangela udokotela ukuthi a-ode ukuhlolwa okwengeziwe.

Ukulungiselela kanjani ukuhlolwa kwegazi kwe-MCHC

Ukuhlolwa kwegazi kweMean Corpuscular Hemoglobin Concentration (MCHC) kuvame ukufakwa njengengxenye yesibalo segazi eliphelele (CBC). Ukulungiselela lokhu kuhlolwa ngokuvamile kuqondile, futhi ngokuvamile akudingi izinguquko ezithile zokudla noma indlela yokuphila. Nayi eminye imihlahlandlela ejwayelekile okufanele uyilandele:

• Ukuzila ukudla: Ezimweni eziningi, ukuzila ukudla akudingekile ukuze kuhlolwe igazi le-MCHC. Ungadla futhi uphuze njengokujwayelekile ngaphambi kokuhlolwa.
• Imithi: Yazisa umhlinzeki wakho wezempilo mayelana nanoma yimiphi imithi, izithasiselo, noma amakhambi okwelapha owathathayo njengamanje. Eminye imithi ingase ibe nomthelela emiphumeleni yokuhlolwa kwegazi, ngakho-ke umhlinzeki wakho wokunakekelwa kwezempilo angase anikeze imiyalelo ethile mayelana nokuqhubeka noma ukuyeka imithi ethile okwesikhashana.
• I-Hydration: Ukuhlala unamanzi amaningi kuyancomeka, njengoba kungenza kube lula kumhlinzeki wezempilo ukuthi adonse igazi. Kodwa-ke, awudingi ukuphuza amanzi amaningi kakhulu kulokhu kuhlolwa.
• Ukuphumula: Uma unokukhathazeka noma ukwesaba izinaliti, kubalulekile ukuthi uhlale uzolile ngesikhathi sokudonsa igazi. Ukuzijwayeza amasu okuphumula noma ukwazisa umhlinzeki wezokunakekelwa kwempilo nganoma yikuphi ukukhathazeka kungasiza ekuqinisekiseni ukuzizwisa okushelelayo.
• Izingubo: Gqoka izingubo ezinemikhono ekwazi ukugoqeka kalula, njengoba igazi livame ukudonswa endaweni yangaphakathi yendololwane.

Udokotela Ukuncoma nini ukuhlolwa kwegazi kwe-MCHC?

Udokotela angase anikeze ukuhlolwa kwe-MCHC uma umuntu ebonisa izimpawu noma izimpawu ze-anemia. I-anemia wukuphazamiseka kwegazi lapho umzimba ungakhiqizi amangqamuzana egazi abomvu anempilo, okuholela ekwehleni kwekhono lokuletha umoya-mpilo ezithweni nasezicutshini. Ukuhlolwa kwe-MCHC kuyingxenye yeqembu lokuhlola okwaziwa ngokuthi ama-RBC indices, okusiza ukuchaza izici ezihlukahlukene zomzimba zamaseli abomvu egazi. I-MCHC, kanye nokunye ukuhlola kwenkomba ye-RBC, kungasiza ekuxilongeni nasekuhlukaniseni izinkinga zegazi ezifana ne-anemia. Ihlola ukuthi igazi lethu liwuthwala ngokuphumelelayo umoya-mpilo.

Yiziphi izimpawu zamazinga egazi e-MCHC aphansi naphezulu?

Amazinga e-medium corpuscular hemoglobin concentration, kungakhathaliseki ukuthi aphezulu noma aphansi, avame ukuhlotshaniswa nezimpawu ezifanayo. Lokhu kungenxa yokuthi womabili amazinga e-MCHC aphezulu naphansi axhunyaniswa nokuncipha kokuthuthwa komoya-mpilo, okungaholela ekukhathaleni okukhulu. Ezinye izimpawu nezimpawu ezihlobene nokugxila okuphezulu nokuphansi kwe-MCHC kungabandakanya:

• Ubuthakathaka nokukhathala
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ukuphelelwa umoya
• Isikhumba esiphaphathekile nezinsini
• Isiyezi noma ikhanda
• Ukuntuleka kokuhlushwa
• ubuhlungu besifuba

Imiphumela Yokuhlolwa Kwegazi ye-MCHC

Ireferensi noma ububanzi obujwayelekile be-MCHC bungase buhluke kulabhorethri eyodwa kuya kwenye. Ngokuvamile, uhla lwereferensi luwela phakathi kwamagremu angu-32 idesilitha ngalinye (g/dL) kanye namagremu angu-36 ekhulwini (noma amagremu angu-320 ilitha kuya ku-360 amagremu ilitha ngalinye). Kwabanye abantu, imiphumela yokuhlolwa kwegazi ingase ibonise amazinga aphakeme e-MCHC, amazinga aphansi e-MCHC noma ububanzi obujwayelekile be-MCHC.

Liyini Ibanga Elijwayelekile Lamazinga Egazi e-MCHC?

Isilinganiso senani le-MCHC sisukela ku-32–36 amagremu idesilitha ngayinye (g/dL) noma 320–360 amagremu ilitha ngalinye (g/L), kuye ngendawo yokucwaninga. Amanani angaphezu kwalolu banga angase abonise i-anemia.

Yini engabangela ukuhlolwa kwegazi kwe-MCHC okuphansi nokuphezulu?

I-MCHC ephansi ingabangelwa:

• Ukuntuleka kwe-iron (noma ngaphandle kwe-anemia)
• Ubuthi obuholayo
• I-Thalassemias
• I-Sideroblastic anemia
• I-anemia yezifo ezingapheli

Ama-MCHC aphezulu angabangelwa izici ezihlukahlukene. Isibonelo, i-MCHC yomuntu ingakhushulwa ngokuzenzela ngenxa yesimo esingavamile sokuzivikela komzimba esibizwa nge-Cold agglutinin disease (CAD). I-CAD yisimo lapho i- izivikeli mzimba ihlasela ngephutha amangqamuzana egazi abomvu emzimbeni.

Ama-MCHC aphezulu ane-anemia angabangelwa:

• I-Autoimmune hemolytic anemia
• Ukusha kanzima
• I-Hereditary spherocytosis
• Isifo sesibindi
• Hyperthyroidism
• Isifo se-sickle cell
• Isifo se-Hemoglobin C

Ngenzenjani uma nginegazi le-MCHC eliphansi neliphezulu?

Amazinga e-MCHC aphansi naphezulu angaphathwa ngezindlela ezihlukahlukene, kuye ngesimo esiyisisekelo. Kwezinye izimo, ukwelashwa kungase kuhlanganise i-iron supplementation, i-folate intake, noma ukuntuleka kwe-vitamin B12. Ukuze uthole i-anemia eyingozi kakhulu yofuzo noma ezinye izimo eziyinkimbinkimbi, ukumpontshelwa igazi, imithi, noma ukufakelwa komnkantsha wamathambo kungase kudingeke. Kubalulekile ukubonana nodokotela ukuze uthole ukuthi iyiphi indlela yokwelapha efanelekile yomuntu ngamunye.

Isiphetho

I-MCHC isilinganiso senani le-hemoglobin ekhona kumaseli abomvu egazi. Iwusizo kakhulu uma isetshenziswa ngokuhambisana neminye imiphumela ye-CBC futhi ingasiza ekuhlonzeni izimbangela eziwumsuka ze-anemia nokubikezela ukubikezelwa kwabantu abangenayo i-anemia. Lawula impilo yakho nge CARE Izibhedlela. Hlela ukuhlolwa kwegazi okonga imali ye-MCHC namuhla.

Imibuzo Evame Ukubuzwa

1. Ingabe umuntu kufanele akhathazeke uma izinga lakhe le-MCHC liphansi kakhulu?

Izimpendulo. I-MCHC isho okuphansi noma ingase ibonise i-anemia ebangelwa ukuphazamiseka kokushoda kwensimbi. Kunezinhlobo ezimbalwa ezithambile nezilawulekayo ze-anemia ezingathinti. Ezinye izinhlobo zingase zibe yizifo ezingelapheki impilo yonke, nakuba ziyelapheka ngomuthi kanye nokulungiswa kokudla.

2. Yiliphi izinga le-MCHC elithintekayo?

Izimpendulo. I-MCHC engaphansi kuka-31 g/dL noma ngaphezulu kuka-37 g/dL ibhekwa njengengavamile futhi kufanele iphinde ihlolwe.