Igama elithi "Mean Corpuscular Volume," noma "MCV," libhekisela esilinganisweni sosayizi ovamile wengqamuzana elibomvu legazi. Ukuze kuhlolwe futhi kulandelelwe impilo ejwayelekile, ukuhlolwa kwegazi le-MCV kuyindlela yokuhlola ebalulekile. Lokhu kuhlola kufakwe ekuhlolweni kwegazi okuvamile okubizwa ngokuthi i-CBC (Qedela Isibalo Segazi). 

Kuyini Ukuhlolwa kwe-MCV?

Uchwepheshe wezokwelapha angasebenzisa izimpawu ezithile ukuze alinganise izici ezihlukahlukene zamangqamuzana egazi abomvu. I-MCV, noma ivolumu ye-corpuscular, isho umthamo ojwayelekile nosayizi wamaseli abomvu egazi, athwala umoya-mpilo kuwo wonke umzimba. Ukuhlolwa kwegazi kwe-MCV amazinga aphezulu angase abe inkomba yesimo esifana nalokhu isifo sesibindi noma ukuntuleka kwamavithamini. Amazinga aphansi we-MCV ngokuvamile ahlotshaniswa ne-anemia ebangelwa ukuntuleka kwensimbi.

Inhloso yokuhlolwa kwegazi kwe-MCV

Ukuhlolwa kwe-MCV kusho ukukala izimo ezilandelayo:  

• Ukuhlola izimpawu ze-anemia ezingaba khona njengokukhathala, ibala eliphaphathekile, nokuba nekhanda elilula.
• Ukuhlola okunye ukungahambi kahle kwegazi, njengeseli elimhlophe legazi elingavamile noma isibalo seplatelet.
• Ukuhlukanisa phakathi izinhlobo ezahlukene ze-anemia.
• Kubantu abanezimo ezithile zezokwelapha njengesilinganiso sokubikezela
• Njengokuhlolwa okwengeziwe kwezinkinga eziningi zezokwelapha

Yenziwa kanjani i-MCV?

Isampula yegazi elikhishwe engalweni yesiguli liyathathwa ukuze lihlolwe, bese lithunyelwa elebhu ukuze lihlolwe. Indawo yomjovo wesiguli izosulwa ngotshwala nguchwepheshe wezokwelapha. Ukuvimbela ukugeleza kwegazi ukuze umthambo ubonakale kalula, bazonamathisela ibhande lenjoloba ngaphezu kwendawo. Uchwepheshe wezokwelapha uzokhipha inaliti ngemva kokukhishwa komthamo wegazi elidingekayo.

Isampula yegazi lizohlolwa ngokucophelela ngesibonakhulu ngu-a uchwepheshe lab, ozophawula imininingwane ngamangqamuzana egazi, kuhlanganise nobukhulu obuvamile bamangqamuzana abomvu egazi. Asikho isidingo samalungiselelo athile adingekayo kulokhu kuhlolwa ngoba kuyingxenye yohlolo olujwayelekile lwe-CBC. Kuthatha imizuzu embalwa kuphela ukuqedela inqubo. Ukumisa ukopha endaweni yomjovo, uchwepheshe wezokwelapha uzoyibhandisha futhi asebenzise ibhola likakotini. Isiguli kufanele sivunyelwe ukuthi sihambe ngokushesha uma kungekho zimpawu, njengesiyezi, zikhona. 

Asho Ukuthini Amazinga Aphezulu we-MCV?

Ukuhlolwa kwegazi okubonisa izinga eliphezulu le-MCV (ngaphezulu kuka-100 fl) kubonisa i-macrocytic anemia futhi kubonisa ukuthi umuntu unama-RBC amakhulu kunokuvamile. Ibanga lokuhlolwa kwegazi okujwayelekile/okujwayelekile kwe-MCV ngama-femtoliters angama-80 kuye kwayi-100 (fl).  

Izinto ezilandelayo zingase zibe nomthelela emazingeni aphakeme e-MCV:

• Ukuntuleka kwe-Vitamin B12 noma B9 - Ukungajwayelekile kwe-RBC nokungalingani kosayizi kubangelwa Vitamin B12 kanye nokuntuleka kwe-B9.  
• I-Autoimmune Gastritis Ukuvuvukala komzimba wesisu kanye nengxenye engenhla kuwuphawu lwesifo esingelapheki esaziwa nge-autoimmune gastritis. Ukuntuleka kwe-folate kubangelwa ukuqhubeka kwalesi sifo, futhi lokhu kubangela i-anemia ye-macrocytic. 
• Isifo Sesibindi - Ukwakheka nokwakheka kwamaseli e-RBC kungashintshwa ukugula kwesibindi. Isibonelo, ukukhuphuka kwe-cholesterol ekwakhekeni kwama-RBC, okuthinta usayizi wamaseli, kungenzeka kakhulu kulabo abanesifo sesibindi.
• Ukuphuza Utshwala Okungapheli - Umnkantsha, okuyindawo lapho amangqamuzana abomvu egazi enziwa khona, uphazamiseka ngenxa yokuluthwa utshwala. Ngenxa yokubala okuphansi kwe-RBC noma ama-RBC amakhulu kakhulu, izinga le-MCV lingase likhuphuke.
• I-Hypothyroidism - Ukukhiqizwa kwama-RBC kubangelwa amahomoni egilo. Ngakho-ke, iziguli ze-hypothyroid zisengozini yokuthola i-anemia.  

Udokotela Ukuncoma Nini Ukuhlolwa Kwe-MCV?

Uma izimpawu ze-anemia, ikakhulukazi lezo ze-anemia ye-macrocytic kanye ne-microcytic, ziphakama, uchwepheshe wezokwelapha uvame ukweluleka ukuthi kwenziwe ukuhlolwa kwegazi kwe-MCV. Lezi zimpawu zihlanganisa-

• Ukuphefumula ubunzima
• Ukulahlekelwa kwesifiso
• Ukuthukuthela
• Ukushaya kwenhliziyo okungajwayelekile (arrhythmia)
• Ubuthakathaka noma ukukhathala 
• Ukuba ndikindiki okwedlulele kanye nokuluma 
• Unenkinga yokugxila

Imiphumela ye-MCV

Usayizi wamangqamuzana egazi abomvu nevolumu kukalwa kusetshenziswa ukuhlolwa kwe-MCV. Ibanga elijwayelekile lokuhlolwa kwe-MCV liphakathi kuka-80 fl no-100 fl. Umuntu uthambekele kakhulu ekutholeni noma esevele ene-microcytic anemia uma izinga labo le-MCV lingaphansi kuka-80 fl. Ngokuphambene, bangakwazi ukuthuthukisa i-macrocytic anemia uma amazinga abo e-MCV ephakeme kuno-100 fl.

Liyini Ibanga Elijwayelekile Lamazinga e-MCV?

Kuye ngeminyaka yomuntu ngamunye, ubulili, kanye nendlela yokuhlola ilebhu yokuxilonga esetshenziswa uhla olujwayelekile lokuhlolwa kwegazi lwe-MCV kusampula yegazi lungashintsha.