I-serum glutamic-oxaloacetic transaminase (SGOT), eyaziwa nangokuthi i-aspartate aminotransferase (AST), ukuhlolwa kwe-serological okusetshenziselwa ukukala amazinga e-AST enzyme egazini. I-AST iyi-enzyme yesibindi engangena emgudwini wegazi lapho i- isibindi silimele.

Kuyini ukuhlolwa kwe-SGOT?

Ukuhlolwa kwe-SGOT kuwukuhlola kwe-serological okulinganisa eyodwa yama-enzyme amabili esibindi (i-SGOT ne-SGPT). Ngaphezu kwesibindi, i-enzyme ye-SGOT itholakala nasebuchosheni, enhliziyweni, ezinso nasemisipha.

Inhloso yokuhlolwa kwe-SGOT

Isibindi siyisitho esibalulekile esinesibopho sokwenza imisebenzi ebalulekile yomzimba, okuhlanganisa:

• Ukukhipha ubuthi nokuhlanza igazi
• Ukuphefumula nokuphefumula izakhamzimba ezivela ekudleni
• Isebenza njengeyunithi yokugcina amavithamini futhi iwakhiphe ukuze akhule futhi athuthuke

Ukuze ahlole ukusebenza kwesibindi, udokotela angase anikeze izivivinyo ezimbili zokuhlaziya ama-enzyme esibindi, okungukuthi:

• I-Serum glutamic-oxaloacetic transaminase (SGOT)
• I-Serum glutamic-pyruvic transaminase (SGPT)

Lawa ma-enzyme ngokuvamile aqukethwe esibindini. Nokho, lapho isibindi sigcina umonakalo ngenxa yezici ezihlukahlukene, njengokuhola indlela yokuphila enganyakazi noma engenampilo, la ma-enzyme angangena egazini. Lokhu kuba khona kungabonakala ngokuhlolwa kwe-SGOT/SGPT. Empeleni, ukuhlola ukusebenza kwesibindi kwenziwa ngokulinganisa amazinga e-AST/SGPT nama-enzyme e-SGOT/ALT kusampula yegazi. Amazinga aphakeme alawa ma-enzyme angaphezu kwebanga elinconyiwe angase abonise ukulimala kwesibindi.

Kufanele ngikuthole nini lokhu kuhlolwa kwe-SGOT?

Udokotela angase anikeze ukuhlolwa kwe-SGOT ukuze ahlole ukulimala noma ukulimala kwesibindi. Ukusebenza kahle kwesibindi kuncike ezintweni eziningana, okuhlanganisa ukudla komuntu nendlela yokuphila. Ukudla okungenampilo, ukuphila ngendlela enganyakazi, nezinye izici ezifana nokukhuluphala ngokweqile nokuphuzwa kotshwala ngokweqile kungase kubangele ukulimala kwesibindi futhi kuphazamise ukusebenza kwaso. Lapho isibindi sonakalisiwe, ama-enzyme angase avuze emgudwini wegazi, okuphumela ezingeni eliphezulu lala ma-enzyme egazini.

Uma umuntu enezici ezithile zobungozi ezingase zilimaze isibindi, udokotela angase atuse ukuhlolwa kwe-SGOT. Lezi zici zobungozi zingabandakanya okulandelayo:

• Umlando womndeni wesifo sesibindi
• Izimpawu zokulimala kwesibindi, njengokuncipha kwesisindo esingaqondakali
• jaundice

Ukuhlolwa kwe-SGOT kungase futhi kunconywe ukuze kuqashwe ukuqhubeka kwezifo ezithile zesibindi noma ukwelashwa kwazo, njengalapho kwenzeka khona i-cirrhosis yesibindi. Ukwengeza, njengoba i-enzyme ye-SGOT ikhona nakwezinye izitho ngaphandle kwesibindi, ukuhlolwa kwe-SGOT kungasiza ekutholeni umonakalo noma ukungasebenzi kahle kulezi zitho. Imvamisa, ekuxilongeni kokulimala kwesibindi, kokubili ukuhlolwa kwama-enzyme esibindi kuyacatshangelwa kanye nezinye izimpawu ezihambisana naso.

Kwenzekani ngesikhathi sokuhlolwa kwe-SGOT?

Ukuhlolwa kwe-SGOT kwenziwa kusetshenziswa isampula yegazi eliqoqwe esigulini yi-phlebotomist. Phakathi nenqubo, i-phlebotomist ithola umthambo engalweni yesiguli, ifake i-tourniquet, futhi isebenzisa inaliti ukuze idonse igazi. Igazi eliqoqiwe libe selifakwa eshubhuni, kamuva elisetshenziselwa ukuhlola ukuba khona kwe-enzyme.

Inqubo yokuhlolwa kwe-SGOT

Isampula yegazi lihanjiswa elabhorethri, lapho uchwepheshe oqeqeshiwe enza ukuhlaziya, futhi imiphumela yokuhlolwa ibikwa ngamayunithi ilitha ngalinye legazi.

Ukusetshenziswa kokuhlolwa kwe-SGOT

Ukuhlolwa kwe-SGOT kungase kusetshenziswe udokotela noma umhlinzeki wezokunakekelwa kwempilo ukuze ahlonze izifo zesibindi noma ukulimala kwesibindi. Lapho isibindi sonakalisiwe, i-enzyme ye-SGOT ingena egazini, okuholela ekwandeni kwamazinga ayo egazini. Ngakho-ke, amazinga e-SGOT aphezulu kakhulu kunokujwayelekile egazini angasiza ekuboneni izinga lokulimala kwesibindi. Ukwengeza, lokhu kuhlolwa kungase kusetshenziselwe ukuhlola ukusebenza kwesibindi ezigulini ezinezifo zesibindi eziqhubekayo.

Njengoba i-SGOT ikhona nakwezinye izitho, ukulimala noma ukulimala kwezitho ezinjalo kungabangela amazinga aphezulu e-enzyme ye-SGOT egazini. Isibonelo, ezimeni zokulimala kwemisipha noma ukuhlaselwa yinhliziyo, amazinga e-SGOT angase akhuphuke egazini.

Ungalungiselela kanjani ukuhlolwa kwe-SGOT?

Ukuhlolwa kwe-SGOT ukuhlolwa kwegazi okujwayelekile okubandakanya ukuqoqa isampula yegazi. Akudingi noma yimaphi amalungiselelo akhethekile, njengokuzila ukudla, ngaphambi kokuba igazi liqoqwe. Kodwa-ke, uma isiguli sithatha imithi noma izithasiselo zezempilo, kungase kudingeke ukulungisa noma ukuyeka umthamo. Lokhu kufanele kuxoxwe nodokotela owelaphayo ngaphambi kokwenza noma yiziphi izinguquko noma izinguquko.

Amanani wemiphumela yokuhlolwa kwe-SGOT

Nakuba amanani ama-enzyme e-SGOT angase ahluke kancane kuye ngendlela yokuhlola ilabhorethri, izinga elivamile elivamile lama-enzyme e-SGOT linikezwa embikweni wokuhlola.

Izinga le-SGOT egazini liyahlukahluka ngobulili. Ngokuvamile, uhla olujwayelekile lwe-SGOT kwabesifazane lungaphansi kwamayunithi angama-45 ilitha, kanti uhla olujwayelekile lwabesilisa luba phakathi kwamayunithi ayi-12 no-50 ilitha.

Izinga le-SGOT eliphansi

Amazinga e-SGOT aphansi kunokujwayelekile angase abe ngenxa yezinto ezihlukahlukene, ezihlanganisa:

• Izimo zofuzo
• Izifo ezizenzakalelayo
• Izifo zesibindi
• Izifo zezinso
• Ukuntuleka kwamavithamini

Inani eliphakeme kakhulu lama-SGOT

I-SGOT isho ukuthi iphezulu noma ingakhombisa izinkinga ezimbalwa zezempilo, njenge:

• Ukuqina kwesibindi
• Isifo sokusha kwesibindi
• Ukulimala kwesibindi
• Umdlavuza wesibindi
• I-Cholestasis
• Ukulimala kwenhliziyo, izinso, amathambo, noma imisipha

Amazinga e-SGOT aphakeme ekuhlolweni kwe-SGOT ngokuvamile abonisa ukungasebenzi kahle kwesibindi, nakuba kungase kungabi njalo. Ezinye izici, njengemithi, iminyaka, nobulili, zingaholela ekwandeni kwamazinga e-SGOT.

Isiphetho

I-SGOT ne-SGPT zisebenza njengezimpawu ezibalulekile zokusebenza kwesibindi. Amazinga aphakeme alawa ma-enzyme egazini angase abonise isifo sesibindi noma ukulimala. Ngaphezu kwalokho, izinga eliphezulu le-SGOT lingase libonise izifo noma ukuphazamiseka kwezinye izitho lapho zikhona. Ngokuvamile, kusetshenziswa ukuhlolwa kwe-SGOT ukuze kuhlolwe ukusebenza kwesibindi nokuhlonza isifo sesibindi ezigabeni zaso zokuqala.

Imibuzo Evame Ukubuzwa

1. Ziyini izindleko zokuhlolwa kwe-SGOT?

Izimpendulo. Intengo yokuhlolwa kwe-SGOT ingasukela ku-Rs. 100 kuya ku-Rs. 200.

2. Ingabe izinga eliphezulu le-SGOT liyingozi?

Izimpendulo. Amazinga e-SGOT aphakeme ngaphezu kwezinkambiso ezinconyiwe zobulili obuthile angase abe yimbangela yokukhathazeka futhi agunyaze ukuhlolwa okwengeziwe.