I-SGPT imele i-Serum Glutamic Pyruvic Transaminase enzyme, enye ebizwa ngokuthi i-GPT noma i-ALT enzyme, okuyi-enzyme ekhishwa isibindi. Le enzyme ikhona emisipha, inhliziyo, izinso nesibindi. 

Isibindi siyisitho esibalulekile esibhekene nokuqeda izinto ezinobuthi egazini. Kuyasiza futhi ekukhiqizeni ijusi ye-bile equkethe ama-enzyme e-ALT/GPT. Ama-enzyme e-SGPT asebenza ngokudiliza amaprotheni ayinkimbinkimbi abe amandla. Ukuhlolwa kwe-SGPT kungasiza ukuxilonga ukuphazamiseka noma izifo zesibindi ngokulinganisa izinga lama-enzyme e-SGPT akhona kusampula yegazi. 

Kuyini ukuhlolwa kwe-SGPT?

Ukuhlolwa kwe-SGPT kuyinqubo yokuxilonga ye-serological esetshenziselwa ukuhlaziya izinga lama-enzyme e-SGPT akhona kusampula yegazi. Lesi sivivinyo sinikeza imininingwane ku- impilo yesibindi futhi ngokuvamile isetshenziselwa ukuqapha izimo zesibindi. Ayikho imiphumela emibi eyaziwayo ehlotshaniswa nalokhu kuhlolwa. E-India, intengo yokuhlolwa kwegazi ye-SGPT isukela phakathi kwama-Rs. 90 kanye nama-Rs. 180.

Inhloso yokuhlolwa kwe-SGPT

Udokotela angase anikeze ukuhlolwa kwe-SGPT ngezizathu ezihlukahlukene, kusukela ekuhloleni ukulimala kwesibindi okusekelwe ezimpawu zomzimba ukuze kuqashwe ukusebenza kokwelashwa kwesifo sesibindi. Isinqumo sokuhlolwa kwe-SGPT senziwa kangcono ngudokotela.

Kufanele ngikuthole nini lokhu kuhlolwa kwe-SGPT?

Udokotela angase atuse ukuhlolwa kwegazi kwe-SGPT uma esola ukulimala kwesibindi ngokusekelwe ezimpawini ezifana nalezi:

• Ukungakhululeki esiswini
• I-nausea
• Ukuvota
• Ukukhathala okuqhubekayo noma ukukhathala
• Ukulinyazwa okulula

Ezinye izimpawu ezingase zibonise izifo ezinzima zesibindi zihlanganisa:

• Umchamo omnyama
• Izitulo eziphaphathekile
• I-Jaundice (isikhumba namehlo aphuzi)
• Ukuvuvukala kwesisu
• Ukuvuvukala komlenze

Ukuhlolwa kwe-SGPT kungase futhi kunconywe udokotela ngokuhlolwa okujwayelekile kwempilo yesibindi ezimweni lapho isiguli sibhekene nezici ezithile eziyingozi ezandisa amathuba okuba nezifo zesibindi. Lezi zici zobungozi zingafaka:

• Ukuba nomlando wezifo zesibindi noma ukuphazamiseka
• Ukusetshenziswa kotshwala obunzima
• Diabetes
• Ukuchayeka ku-hepatitis
• Ukukhuluphala
• Ukusetshenziswa kwemithi ethile 

Ngaphezu kwalokho, ukuhlolwa kwe-SGPT kungase kunconywe udokotela ukuze alandelele ukuqhubeka kokwelashwa kwesibindi ezigulini ezilulama ezifweni zesibindi.

Kwenzekani ngesikhathi sokuhlolwa kwe-SGPT?

Ukuhlolwa kwe-SGPT kwenziwa ngokuthola isampula yegazi esigulini. I-phlebotomist ivamise ukudonsa igazi emithanjeni bese ilithumela elabhorethri ukuze lihlolwe. Inqubo yokudonsa igazi ithatha cishe imizuzu emi-5 futhi ngokuvamile ayibuhlungu njengokulunywa yintuthwane. Ngokuvamile ayikho imiphumela emibi evela kule nqubo.

Inqubo yokuhlolwa kwe-SGPT

A uchwepheshe welebhu ihlaziya isampula yegazi ukuze ihlole izinga le-SGPT. Umbiko wokuhlola ukhiqizwa ngokusekelwe ekuhlaziyweni, okungasiza odokotela ukuthi bahlonze noma bakhiphe izifo zesibindi.

Ukusetshenziswa kokuhlolwa kwe-SGPT

Ukuhlolwa kwegazi kwe-SGPT kusetshenziselwa ngokuyinhloko ukuthola izifo noma ukulimala esibindini sesiguli. Ingase futhi inikeze imininingwane ku- izingozi zezinso, inhliziyo, noma izifo ezithile zeqembu lemisipha noma ukulimala. Odokotela bangase banqume ukuthi lokhu kuhlolwa kwenziwe ngezikhathi ezithile ukuze kuqashwe impilo yesibindi.

Ungalungiselela kanjani ukuhlolwa kwe-SGPT?

Ngokuhlolwa kwe-SGPT, azikho izinyathelo eziqondile okumelwe zithathwe. Ukuzila ukudla kungase kungadingeki lapho unikeza isampula. Noma yiziphi izinyathelo zokuphepha okufanele zithathwe zizophakanyiswa udokotela owelaphayo.

Amanani wemiphumela yokuhlolwa kwe-SGPT

I-Serum Glutamic Pyruvic Transaminase (SGPT) enzyme inobubanzi obujwayelekile obuchaziwe. Izinga le-enzyme ye-SGPT ekhona kusampula yegazi likalwa ngamayunithi ngelitha. Inani eliphakeme kunelijwayelekile le-enzyme ye-SGPT lingabonisa ukulimala kwesibindi noma izifo, ezidinga ukunakekelwa kwezokwelapha ngokushesha.

Ibanga elijwayelekile le-SGPT lingahluka kubo bobabili abesilisa nabesifazane. Izinto ezimbalwa zingathonya uhla olujwayelekile lwe-SGPT yegazi, okuhlanganisa:

• Ubudala
• Ukuphuza utshwala
• Ukusebenzisa kabi izidakamizwa
• Ukukhuluphala
• Ukutheleleka nge-Hepatitis
• I-Epstein Barr virus
• Isifo se-Celiac
• Ukuvuvukala kwe-Gallbladder

Kwabesilisa, uhla olujwayelekile lwe-SGPT lungahluka kusuka kumayunithi angama-29 kuye kwangama-33 ilitha, kanti kwabesifazane, amanani ajwayelekile we-SGPT angahluka kusuka ku-19 kuya ku-25 amayunithi ilitha. Kodwa-ke, amazinga e-SGPT afika kumayunithi angama-55-56 ilitha abuye athathwe njengephephile kubo bobabili abesilisa nabesifazane.

I-SGPT isho ukuthi iphezulu noma ingakhombisa izimo zezempilo ezahlukahlukene, okuhlanganisa:

• Ukutheleleka nge-Acute Hepatitis virus (A, B, C)
• Diabetes
• Ukukhuluphala
• Isifo se-Celiac
• Ukuvuvukala kwe-Gallbladder
• I-Epstein Barr virus

Amazinga aphansi e-SGPT angabonisa ukusebenza kahle kwesibindi kanye nempilo yesibindi iyonke. Kodwa-ke, zingase zitholakale nasezimeni ezifana nokuntuleka kwe-Vitamin B6. Izinto ezivamile nezimo ezingaholela emazingeni aphansi e-SGPT embikweni wokuhlolwa kwegazi we-SGPT zifaka:

• Ukubhema
• Ukuphuza utshwala
• Ukwehla kwe-Vitamin B6
• Ukwelashwa kokufaka esikhundleni seHormone 

Isiphetho

Ekuphetheni, ukuhlolwa kwegazi kwe-SGPT kuyindlela yokuxilonga esetshenziselwa ukuhlola impilo yesibindi nokubona izifo noma ukuphazamiseka okuthinta isibindi. I-SGPT iyi-enzyme ehlotshaniswa nomsebenzi wesibindi. Okuphakeme noma okuphansi kunobubanzi obujwayelekile bokuhlolwa kwe-SGPT obunconyiwe kungase kubonise izimo zezokwelapha eziphazamisa ukusebenza kwesibindi.

Imibuzo Evame Ukubuzwa

1. Uyiqonda kanjani imiphumela yokuhlolwa kwe-SGPT?

Izimpendulo. Imiphumela yokuhlolwa kwe-SGPT ikalwa ngamayunithi ilitha ngalinye legazi. Ububanzi bereferensi obunempilo ngokuvamile bunikezwa embikweni wokuhlolwa kwegazi we-SGPT. Ukuhlola amazinga e-enzyme atholakele emiphumeleni kunganikeza ukuqonda ngesimo samazinga e-SGPT egazini. Uma izinga le-enzyme ye-SGPT liwela phakathi kwe-7 kuya ku-56 ilitha ngalinye, kubhekwa njengokujwayelekile, futhi kungase kube khona isizathu sokukhathazeka.

2. Kwenzekani uma izinga le-SGPT liphezulu?

Izimpendulo. Nakuba kungase kungabi khona izimpawu ezisheshayo zamazinga e-SGPT aphakeme, udokotela angase atuse ukuhlolwa okwengeziwe ukuze aqinisekise ukuxilongwa.