I-Hematology kanye Ne-Bone Marrow Transplant

Isibhedlela I-Bone Marrow Transplant engcono kakhulu e-Indore

Ukufakelwa komnkantsha, okwaziwa nangokuthi i-stem cell transplant noma i-haematopoietic stem cell transplant, kuyindlela engahlinzeki esetshenziselwa ukugcwalisa umongo wethambo owonakele noma ocekeleke phansi ngamaseli esiqu somnkantsha onempilo. Phakathi nenqubo, ama-stem cells angeniswa egazini lesiguli kusetshenziswa i-catheter ye-venous ephakathi, efana nenqubo yokumpontshelwa igazi. Amaseli ashintshayo angavela emzimbeni wesiguli noma kumnikeli. Le ndlela yokufakelwa iphatha ngokuphumelelayo izifo ezihlukahlukene zegazi nezivikeli mzimba ezithinta umnkantsha, njenge-leukemia, i-myeloma, ne-lymphoma.

Ezibhedlela ze-CARE CHL, e-Indore, uMnyango Wezempilo kanye Nokufakelwa Kwethambo Lomnkantsha ugxile ekwelapheni igazi eliyinkimbinkimbi, i-lymph node, nezifo zomnkantsha. Iziguli zithola ukunakekelwa okuphelele ngaphansi kophahla olulodwa, okuhlanganisa ukuxilonga nokwelashwa kwezimo eziningi zegazi. Ibhange lethu legazi eligcwele ngokugcwele, iyunithi yokufakelwa komnkantsha ozinikele, kanye nelebhu ye-hematology yesimanjemanje isenza sihluke kwabaqhudelana nabo.

Izinhlobo Zokufakelwa Kwethambo Lomnkantsha ohlinzekwa ezibhedlela ze-CARE CHL, e-Indore

• Ukufakelwa kwe-autologous bone marrow (stem cell): Ukufakelwa komnkantsha we-autologous kuhilela ukubuyisela umnkantsha wethambo ogulayo noma owonakele ngamaseli egazi esiguli anempilo. Ngokungafani nokusebenzisa ama-stem cells, ukusebenzisa ama-stem cells esiguli ekufakelweni komnkantsha kunenzuzo enkulu yokugwema noma yiziphi izinkinga zokusebenzisana phakathi kwamaseli anikelayo namaseli esiguli.
• Ukufakelwa kwe-allogeneic: Ukufakelwa kwe-allogeneic bone marrow (stem cell) kuthatha indawo yomnkantsha owonakele kusetshenziswa amaseli egazi anempilo avela kumnikeli.

Izimo lapho ukufakelwa komnkantsha wethambo kuyelulekwa

Izinhlobo eziningi zomdlavuza we-hematological welashwa emnyangweni wethu we-hematology. Sisebenzisa okokusebenza okuthuthukile futhi siqinisekisa ukuthi ukwelashwa kunikezwa ngamaphakheji anenani elifanele. Siphinde silawule izimo ezihlukene ezingezona umdlavuza, okuhlanganisa:

• I-Aplastic Anemia kanye nezinye izifo zokwehluleka komnkantsha - Lezi zimo ezibulalayo zibonakala ngokungakwazi komnkantsha ukukhiqiza izingxenye zegazi ezanele ukuhlangabezana nezidingo zeziguli. Kubantu abanalezi zimo, ukufakelwa ngokushesha kwe-allogeneic stem cell kungase kube inketho esindisa ukuphila.
• I-Thalassemia Major - Lesi simo sofuzo, esibangelwa ukushoda kwe-hemoglobin yefa, sidinga ukuthi iziguli zimpontshelwe igazi njalo ziqala zisencane. Iziguli eziningi ze-thalassemia zingathola ikhambi ngokufakelwa kabusha kwe-allogeneic stem cell transplantation.
• I-Sickle Cell Anemia - Esinye isimo sofuzo se-hemoglobin esiholela ku-anemia, iziqephu ezibuhlungu, imivimbo, nokwehluleka kwezitho. Iningi lalaba bantu lingathola ikhambi ngokufakelwa kwe-allogeneic stem cell.

Ukufakelwa kwe-stem cell kungasindisa impilo ezifweni ezahlukahlukene, kufaka phakathi ama-congenital immune deficiency syndromes, amaphutha azalwa nawo we-metabolic, nokunye. Ukufakelwa kwenziwa futhi ezifweni ezinomdlavuza, njenge:

• I-Acute Myeloid Leukemia - Njalo ngonyaka, sinakekela abantu abaningi abane-acute myeloid leukemia. Indlela yethu yokwelapha ihambisana neminyaka yesiguli nezinye izici ezifanele.
• I-Acute Lymphoblastic Leukemia - Selapha i-acute lymphoblastic leukemia kubantu abadala nasezinganeni. Izinhlelo zokwelapha zinqunywa ngokusekelwe ebukhulwini besifo.
• I-Chronic Myeloid Leukemia - Ithimba lethu lihlinzeka ngokunakekelwa kwekhwalithi ephezulu ezigulini ezine-myeloid leukemia engapheli. Ilabhorethri yethu ye-hematology emisha yenza ucwaningo lwamangqamuzana olunembile ukuze kuqinisekiswe ukuxilonga okunembile.
• I-Acute Promyelocytic Leukemia - Sinikeza izixazululo zokwelashwa ezingabizi kakhulu ze-acute promyelocytic leukemia. Ucwaningo lwethu oluqhubekayo luhlose ukuthuthukisa imiphumela yezifundo zethu zomtholampilo.
• I-Lymphoma ne-Myeloma - Ubuchwepheshe bethu budlulela ngale kwezinhlobo ezahlukene ze-leukemia ukuze buhlanganise izinhlobo eziningi ze-lymphoma ne-myeloma. Sihlaziya ngokucophelela izinhlobo ezincanyana ezithile, eziqhutshwa ukufinyelela kwethu ebangeni elibanzi lokuhlola.

Yini okufanele uyilindele ngesikhathi sokufakelwa kwe-Bone Marrow?

Ukufakelwa komnkantsha wethambo kuzokwenziwa ngokulandela inqubo yokulungisa isimo ehlanganisa i-chemotherapy kanye nemisebe okungenzeka ibe nayo. Inhloso ye-conditioning ukuqeda amangqamuzana omdlavuza, ukucindezela amasosha omzimba, nokulungiselela umzimba ukwethulwa kwamaseli amasha. Lawa ma-stem cell afakwa emzimbeni ngesikhathi sokufakelwa komnkantsha. Uma esetshaliwe kabusha, lawa ma-stem cells athuthela emnkantsheni, lapho aqala khona ukukhiqizwa kwamangqamuzana egazi amasha. Isibalo sakho segazi singakhula ngemva kwenyanga noma ngaphezulu kokukhiqizwa kwamaseli okuqhubekayo.

Uma amangqamuzana egazi egcinwe ngokubanda nokuncibilika ngaphambi kokuba anikezwe isiguli, kuzonikezwa imithi efanele ukuze kuncishiswe imiphumela emibi engase ibe khona evela ezintweni ezilondolozayo ezisetshenziswa phakathi nale nqubo.

Yini okufanele uyilindele ngemuva kokufakelwa kwe-Bone Marrow?

Amaseli amasha ngokushesha aya emnkantsheni lapho engena emzimbeni ukuze aqale ukukhiqiza amangqamuzana egazi amasha. Isikhathi esisithathayo ukuze isibalo segazi sibe ngokwejwayelekile kubantu abathile singase sibe ngaphezu kwenyanga. Ngemva kokuhlinzwa, iziguli kungase kudingeke zihlale esibhedlela isonto lonke noma ngaphezulu ukuze zithole ukuqashwa okuqinile. Ngemva kokufakelwa umnkantsha, bazobhekwa ngeso elibukhali ithimba elinakekela umdlavuza izinsuku ezimbalwa, amasonto, nezinyanga. 

Kuzokwenziwa ukuhlolwa kwegazi njalo, futhi udokotela uzosiza ekulawuleni noma yiziphi izingozi ezingase ziphakame. Isiguli sokufakelwa umnkantsha sisengozini enkulu yokutheleleka nezinye izinkinga phakathi nezinsuku namasonto ngokushesha ngemva kokuhlinzwa, ngakho-ke kubalulekile ukudla kahle, ukuzivocavoca umzimba, nokuhlala uphilile ngalesi sikhathi.

Imiphumela engemihle ngemva kokufakelwa kwe-Bone Marrow

Okulandelayo yimiphumela emibi ehlobene nokufakelwa okulethwa i-chemotherapy kanye ne-radiotherapy esetshenziswa ngesikhathi sokufakelwa:

• Isicanucanu, Ukuphalaza, Ukuphelelwa Isifiso Sokudla
• Ukulahlekelwa Izinwele
• Izilonda Zomlomo
• ukopha
• Fever
• Ukuzala Kwesikhashana Noma Okungapheli
• Ukushiyeka

Izinsiza ezihlinzekwa e-CARE CHL Hospitals, e-Indore

UMnyango Wezempilo Nezokufakelwa Kwethambo Lomnkantsha uhlinzeka ngokufinyelela kulezi zikhungo ezilandelayo:

• I-Bone Marrow Biopsy
• Ukuvunwa kweStem Cell
• Ukukhishwa kwegazi
• Amasu Okufanekisa Athuthukile
• Ukuhlolwa kwegazi
• Ukuvala izikrini
• Izindlela zokuxilonga ze-Molecular

Kungani Khetha Izibhedlela ze-CARE CHL?

Umnyango wethu wenze ngempumelelo inani eliphezulu kakhulu bone Ukufakelwa Komnkantsha kusukela ngoSepthemba 2016 eMadhya Pradesh. Ukwengeza, isikhungo sihlinzeka ngokwelashwa kwe-chemo okungenabuhlungu ngokufinyelela kwe-PICC kanye nendawo yokunakekela izingane ngezikhathi ze-chemo kanye nokumpontshelwa igazi. Ukuze kuhlangatshezwane nezinga eliphezulu kakhulu lokusebenza ngempumelelo, sinikeza ukwelashwa komdlavuza wesimanje kanye nezinsizakalo ze-BMT njengoba sinamagumbi okuhlukanisa i-hepa filter neutropenic anendawo yangaphakathi ye-stem cell apheresis.