I-Acarbose

I-Acarbose

I-Acarbose, umuthi onamandla wokulwa nesifo sikashukela, ingasiza ukulawula amazinga kashukela egazini ngaphandle kokuthikameze ngokuqondile i-insulin. Lo muthi udlala indima ebalulekile ekulawuleni ukumuncwa kwe-glucose ohlelweni lokugaya ukudla, okuwenza ube yithuluzi elibalulekile kubantu abaningi abanenkinga yesifo sikashukela sohlobo 2 noma i-prediabetes.

Yini i-Acarbose?

I-Acarbose imithi elwa nesifo sikashukela esetshenziselwa ukwelapha isifo sikashukela sohlobo 2 futhi, kwamanye amazwe, i-prediabetes. I-oligosaccharide eyinkimbinkimbi esebenza njengesivimbeli sesitashi ngokuvimbela i-alpha-glucosidase, i-enzyme yamathumbu ephula ama-carbohydrate. Lo muthi wehlisa ukugaywa kwama-carbohydrate, wehlise ukumuncwa kwe-glucose kanye namazinga kashukela wegazi we-postprandial.

Ukusetshenziswa kwethebhulethi ye-Acarbose

• Amaphilisi e-Acarbose asetshenziswa ngokuyinhloko ekwelapheni isifo sikashukela sohlobo 2. Basiza ukwehlisa amazinga kashukela uma kuhlanganiswa nokudla nokuzivocavoca. 
• Le alpha-glucosidase inhibitor ibambezela ukusebenza kwama-enzyme athile aphula ukudla okudlile kube ushukela. Le nqubo ibambezela ukugaywa kwama-carbohydrate, ivimbele ukuthi ushukela wegazi ukhuphuke kakhulu ngemva kokudla.
• Umuthi we-acarbose usebenza emathunjini amancane ukuvimba ukuvutshelwa kwama-carbohydrate ayinkimbinkimbi abe yiglucose, ushukela umzimba ongawumunca. Ngokunciphisa ukumuncwa kukashukela emathunjini amancane, i-acarbose isiza ukuphatha amazinga eglucose ngempumelelo.

Ungayisebenzisa kanjani i-Acarbose Tablet

• Amaphilisi e-Acarbose kufanele aphuzwe ngomlomo kathathu ngosuku ngokulunywa kokuqala kokudla ngakunye. 
• Iziguli kufanele ziphuze izidakamizwa ze-acarbose ekuqaleni noma ngesikhathi sokudla ukuze zisebenze kahle kakhulu. Ukuyithatha imizuzu engu-15 ngaphambi kokudla kunciphisa ukusebenza kwayo ngo-50%. Kubalulekile ukwazisa iziguli mayelana nokusetshenziswa okufanele kanye nezinguquko ezingaba khona ekudleni. 
• Iziguli kufanele zigweme iziphuzo ezinoshukela futhi zazi ukuthi ukwenyuka komthamo kancane kancane kuvamile.

Imiphumela Emibi Yezibhebhe ze-Acarbose

I-Acarbose ingabangela kokubili imiphumela emibi evamile kanye neyingozi. 
Imiphumela emibi evamile ye-acarbose ubuhlungu besisu, isifo sohudo, kanye negesi. Lokhu ngokuvamile kwenzeka phakathi namaviki ambalwa okuqala okwelashwa futhi kwehle ngokuhamba kwesikhathi. Iziguli kufanele zixhumane nodokotela bazo uma lezi zimpawu ziqhubeka noma ziba nzima.
Imiphumela emibi kakhulu, nakuba ingajwayelekile, idinga ukunakekelwa kwezokwelapha ngokushesha. Lokhu kubandakanya:

• Ukungezwani Okubi Kakhulu: Izimpawu zingase zihlanganisa izinkinga zokuphefumula, ukuvuvukala kobuso noma umphimbo, ukuqubuka kwesikhumba, noma ukuqubuka.
• Ushukela Wegazi Ophansi (Hypoglycemia): Lokhu kungenzeka uma i-acarbose isetshenziswa neminye imithi yesifo sikashukela. Izimpawu zihlanganisa ikhanda, isiyezi, ukudideka, nokujuluka.
• Izinkinga Zesibindi: Bheka ukuphuzi kwesikhumba noma amehlo nobuhlungu besisu.
• I-Pneumatosis Cystoides Intestinalis: Lesi simo esingavamile sibangela ama-cyst agcwele igesi emathunjini, okuholela ekuqineni. isifo sohudo or ukuqunjelwa.

Ukuqapha

• Izimo Ezithile Zesistimu: Iziguli ezine-ketoacidosis yesifo sikashukela, i-cirrhosis, noma kunzima isifo sesibindi akufanele iphuze lo muthi. 
• Izifo Zamathumbu: Ayifanele futhi kulabo abanesifo samathumbu esivuvukalayo, isilonda sekoloni, noma ukuvaleka kwamathumbu. Abantu abanezinkinga zezinso ezingapheli kudingeka babonane nodokotela wabo ngaphambi kokusebenzisa i-acarbose.
• Ukuqapha Ngemiphumela Emibi: Iziguli kufanele ziqaphele imiphumela emibi engaba khona. Lokhu kufaka phakathi i-pneumatosis cystoides intestinalis, ukungezwani nesikhumba, noma izinkinga zesibindi.
• Isexwayiso se-Hypoglycemia: I-Acarbose inganyusa ubungozi be-hypoglycemia uma isetshenziswa ne-insulin noma i-sulfonylureas. Iziguli kufanele zisebenzise amaphilisi eglucose noma i-glucose ewuketshezi esikhundleni sikashukela wommoba ukulawula ushukela osegazini.

Isebenza kanjani ithebhulethi ye-Acarbose

I-Acarbose, i-oligosaccharide eyinkimbinkimbi, isebenza njenge-inhibitor ephikisanayo neguquguqukayo ye-pancreatic alpha-amylase kanye ne-alpha-glucosidase yamathumbu. Yehlisa ukuqhekeka kwama-carbohydrate ayinkimbinkimbi abe yi-glucose emathunjini amancane. Ngokubambezela ukugaya kwe-carbohydrate, i-acarbose yehlisa ukumuncwa kwe-glucose, okuholela ekwehleni koshukela wegazi ngemuva kokudla kanye namazinga e-insulin.
Ukuze i-acarbose isebenze kahle, iziguli kufanele ziyiphuze ngesikhathi sokudla kokuqala. Lesi sikhathi siqinisekisa ukuthi umuthi ukhona lapho ama-carbohydrate engena ohlelweni lokugaya ukudla, okuwuvumela ukuthi usebenzise umphumela wawo wokwelapha.

Ngingakwazi ukuthatha i-acarbose neminye imithi?

I-Acarbose ingaxhumana nemithi ehlukahlukene, ngakho-ke ukwazisa odokotela ngayo yonke imithi yamanje kubalulekile. 

• Ingase yehlise i-bioavailability ye-digoxin ne-valproic acid. 
• Ingozi ye-hypoglycemia iyanda lapho i-acarbose ihlanganiswa namanye ama-antidiabetesic agents, ikakhulukazi i-insulin noma i-sulfonylureas. 
• Ama-enzyme okugaya aqukethe i-amylase noma i-pancreatin anganciphisa ukusebenza kwe-acarbose. 
• Iziguli kufanele ziqaphele lapho zithatha i-acarbose ngemithi ethinta amazinga kashukela egazini. Ukuqapha amazinga kashukela egazini eduze kakhulu lapho uqala noma uyeka eminye imithi ngenkathi usebenzisa i-acarbose kubalulekile. Njalo thintana nodokotela ngaphambi kokuhlanganisa i-acarbose neminye imithi noma izithasiselo.

Ulwazi Lomthamo

Umthamo wokuqala we-acarbose ngu-25 mg, ophuzwa ngomlomo kathathu ngosuku ngokulunywa kokuqala kokudla ngakunye okuyinhloko. Odokotela balungisa umthamo njalo emavikini angu-4 kuya kwangu-8 ngokusekelwe ekusebenzeni kahle nokubekezelelana. Umthamo omkhulu uyahlukahluka kuye ngesisindo somzimba:

• Kubantu abanesisindo esingama-60 kg noma ngaphansi: 50 mg kathathu ngosuku
• Kulabo abanesisindo esingaphezu kwama-60 kg: 100 mg kathathu ngosuku

Isiphetho

I-Acarbose igqama njengethuluzi elibalulekile lokulawula isifo sikashukela sohlobo 2, enikeza indlela eyingqayizivele yokulawula ushukela wegazi. Ngokunciphisa ukugaya kwe-carbohydrate emathunjini, i-acarbose ithinta amazinga kashukela wangemva kokudla ngaphandle kokuthikameze ngokuqondile i-insulin. Uma isetshenziswa eduze nokudla okunempilo nokuzivocavoca okuvamile, le mithi ingenza umehluko wangempela ekusizeni abantu bagcine ushukela wabo wegazi uhlola.
Nakuba i-acarbose ingaba usizo ngendlela emangalisayo, kubalulekile ukwazi imiphumela yayo engemihle engaba khona futhi uyisebenzise ngendlela efanele. Ukuyithatha ngesikhathi esifanele futhi ukhumbule ukuthi ihlangana kanjani neminye imithi kuyisihluthulelo sokuthola inzuzo enkulu.

FAQ sika

1. Isetshenziselwa ini i-acarbose ngokuyinhloko?

Ukusetshenziswa okuyinhloko kwe-acarbose ukwelapha uhlobo 2 sikashukela mellitus. Kuyasiza ukwehlisa amazinga kashukela uma kuhlanganiswa nokudla nokuzivocavoca. Lo muthi wehlisa ukugaya kwe-carbohydrate, uvimbela ukukhuphuka okubukhali kweglucose yegazi ngemuva kokudla.

2. Ubani okufanele aphuze i-acarbose?

Abantu abanesifo sikashukela sohlobo 2 abadinga usizo lokulawula amazinga kashukela egazini bangazuza ku-acarbose. Ivamise ukunikezwa kanye neminye imithi yesifo sikashukela noma njengokwelashwa okuzimele lapho ukudla nokuzivocavoca kunganele.

3. Ingabe kubi ukusebenzisa i-acarbose nsuku zonke?

I-Acarbose ngokuvamile iphephile ukusetshenziswa nsuku zonke njengoba kunqunywe udokotela. Idizayinelwe ukwelashwa kwesikhathi eside ukuze ilawule amazinga kashukela egazini ngempumelelo. Nokho, iziguli kufanele ziqaphe imiphumela engemihle futhi zilandele imiyalelo kadokotela wazo eduze.

4. Ingabe i-acarbose iphephile? 

I-Acarbose ngokuvamile iphephile uma isetshenziswa njengoba kushiwo. Kodwa-ke, njengayo yonke imithi, ingabangela imiphumela emibi. Imiphumela emibi evamile ubuhlungu besisu, ukuvuvukala, kanye nesifo sohudo. Imiphumela emibi engavamile kodwa eyingozi ingase ihlanganise i-hypoglycemia, ukungezwani komzimba, noma izinkinga zesibindi. Hlala uthintana nodokotela wakho mayelana nezingozi nezinzuzo ezingaba khona.

5. Ubani okungafanele asebenzise i-acarbose? 

Abantu akufanele basebenzise i-acarbose ku:

• Ukungezwani ne-acarbose noma izithako zayo
• Isifo sikashukela i-ketoacidosis
• I-cirrhosis
• Isifo sofuba esiswini
• I-Colonic ulceration
• Ukuvinjelwa kwamathumbu
• Izinkinga zamathumbu ezingapheli 
• Abantu abanenkinga yezinso kufanele babonane nodokotela wabo ngaphambi kokusebenzisa i-acarbose.
• Ingabe i-acarbose iphephile kubantu abanezinkinga zezinso? 

I-Acarbose akufanele isetshenziswe uma izinso zakho zingasebenzi kahle. Uma kukhona ukukhathazeka mayelana nempilo yezinso zakho, udokotela wakho angase ahlole ukusebenza kwezinso ukuze anqume ukuthi izinso zakho zisebenza kahle ngokwanele yini ukuba uphuze lo muthi ngokuphepha.

6. Ngingakwazi ukuthatha i-acarbose ebusuku? 

I-Acarbose ngokuvamile ayithathwa ebusuku. Kufanele kuthathwe kanye nokudla ukuze kuncishiswe ukumuncwa kwama-carbohydrate. Ukuyithatha ebusuku ngaphandle kokudla akuhlinzeki ngezinzuzo ezihlosiwe futhi kungase kubangele imiphumela engemihle.

7. Yisiphi isikhathi esingcono kakhulu sosuku sokuphuza i-acarbose? 

Isikhathi esingcono kakhulu sokuphuza i-acarbose siwukuluma kokuqala kwesidlo esikhulu ngasinye, ngokuvamile kathathu ngosuku. Ukuthatha umthamo ngamunye ekuqaleni kokudla kwakho kubalulekile ukuze umuthi usebenze ngempumelelo ekwehliseni ijubane ukumuncwa kwama-carbohydrate.