I-acetaminophen ene-Codeine

I-acetaminophen ene-Codeine

Ukuphathwa kwezinhlungu ngokuvamile kudinga okungaphezu nje kwemithi eyisisekelo etholakala ngaphandle kwe-counter. Lapho ukudambisa ubuhlungu okuvamile kubonakala kunganele, odokotela bangase banikeze i-acetaminophen nge-codeine, imithi ehlangene enamandla esiza iziguli ukuphatha ubuhlungu obuphakathi kuya kobunzima ngokuphumelelayo.

Lo mhlahlandlela ophelele uchaza yonke into iziguli okudingeka ziyazi mayelana ne-acetaminophen nge-codeine, okuhlanganisa ukusetshenziswa kwayo, umthamo ofanele, imiphumela emibi engase ibe khona, nokucatshangelwa kokuphepha okubalulekile.

Iyini i-Acetaminophen nge-Codeine Medicine?

I-acetaminophen codeine umuthi kadokotela ohlanganisa izinhlanganisela ezimbili ezihlukene zokudambisa izinhlungu. Lo muthi oyinhlanganisela uvame ukutholakala ngaphansi kwegama lomkhiqizo iTylenol.

Umuthi uqukethe izingxenye ezimbili eziyinhloko:

• I-acetaminophen: Isidambisi sobuhlungu nesinciphisi semfiva esekilasini lemithi ebizwa ngokuthi i-analgesics kanye ne-antipyretics.
• I-Codeine: I-analgesic ye-opioid (i-narcotic) esebenza ngqo ebuchosheni kanye nesistimu yezinzwa ukuphatha ubuhlungu

Ukusetshenziswa kwe-acetaminophen codeine

Inhlanganisela ye-acetaminophen ne-codeine isebenza ngezinhloso eziningi zokwelapha ekulawuleni ubuhlungu. Lo muthi ngokuyinhloko usetshenziselwa ukubhekana nobuhlungu obuncane kuya kobumaphakathi lapho amanye ama-painkillers ajwayelekile efakazela ukuthi ayanele.

Umuthi usebenza ngezindlela eziningi ukuze usize:

• Ukuphathwa Kobuhlungu: Kukhulula ngempumelelo ubuhlungu obuncane kuya kobumaphakathi ngokusebenzisa indlela yayo yezenzo ezimbili
• Fever Ukunciphisa: Ingxenye ye-acetaminophen isiza ekwehliseni izinga lokushisa lomzimba
• Isikhukhula Ukucindezelwa: I-Codeine iqondise ngokucacile isikhungo sokukhwehlela sobuchopho ukuze kwehliswe umsebenzi wokukhwehlela

Odokotela banikeza lo muthi ngohlelo lwe-Opioid Analgesic REMS (I-Risk Evaluation and Mitigation Strategy). Lokhu kusatshalaliswa okulawulwayo kuqinisekisa ukusetshenziswa okufanele nokuphepha kwesiguli. Umuthi uza ngezinhlobo ezahlukene ukuze uvumelane nezidingo zesiguli ezahlukene, okuhlanganisa amaphilisi, isixazululo somlomo, kanye ne-elixir.

Ungayisebenzisa kanjani i-Acetaminophen ne-Codeine Tablet

Izinkombandlela Zokuphatha ezibalulekile:

• Iziguli kufanele ziphuze lo muthi ngomlomo njalo emahoreni angu-4 njengoba kudingeka, zilandela ilebula lencwadi kadokotela ngokucophelela.
• Thatha umuthi njengoba uqondiswe ngudokotela
• Ungeqi umthamo onqunyiwe noma imvamisa
• Linganisa amafomu oketshezi ngokucophelela usebenzisa isipuni sokulinganisa esimakiwe noma inkomishi yomuthi.
• Shake ukumiswa ngomlomo kahle ngaphambi kokusetshenziswa ngakunye
• Gcina umuthi ekamelweni lokushisa, kude nomswakama nokushisa

Imiphumela Emibi ye-Acetaminophen ne-Codeine Tablet

Imiphumela engemihle evamile iziguli ezingase zibe nayo ihlanganisa:

• Ukozela kanye nekhanda elilula
• I-nausea nokuhlanza
• ukuqunjelwa
• Kunzima ukuchama
• bekhanda
• Ukukhathala okungavamile noma ubuthakathaka

Imiphumela Emibi Kakhulu: Ezinye iziguli zingase zibe nemiphumela emibi kakhulu edinga ukunakwa ngokushesha. Lokhu kuhlanganisa ubunzima bokuphefumula, ukushaya kwenhliziyo okungajwayelekile, noma ukuphefumula okungajulile. Iziguli kufanele zifune ukungenelela kwezokwelapha eziphuthumayo uma zibona izindebe eziphaphathekile noma eziluhlaza okwesibhakabhaka, izinzipho, noma isikhumba, okungase kubonise ukusabela okunzima.

I-Alergic: Nakuba kungavamile, ezinye iziguli zingase zibe nokungezwani komzimba; izimpawu zihlanganisa isifuba, ukulunywa, ukuqubuka kwesikhumba, nokuvuvukala eduze kwamehlo, ubuso, izindebe, noma ulimi. Noma ibuphi ubunzima bokuphefumula noma bokugwinya budinga ukunakwa ngokushesha.

Izimpawu Zesexwayiso Zokudlula Izidakamizwa: Iziguli kufanele ziqaphele izimpawu zokusebenzisa ngokweqile izidakamizwa ezingaba khona, okuhlanganisa umchamo omnyama, indle enombala okhanyayo, ukungakuthandi ukudla, ubuhlungu besisu, noma amehlo aphuzi nesikhumba. Lezi zimpawu zidinga usizo lwezempilo oluphuthumayo.

Ukuqapha

Ezinye zezinyathelo zokuphepha zihlanganisa:

• Umlando Wezidakamizwa: Iziguli kufanele zazise udokotela wazo mayelana nanoma yikuphi ukungezwani komzimba ne-acetaminophen, codeine, noma eminye imithi ye-opioid ngaphambi kokuqala ukwelashwa. 
• Umlando Wezokwelapha: Odokotela badinga ukwazi nganoma yimuphi umlando wa:
  • Ukuphazamiseka kwengqondo noma ukulimala ekhanda
  • Izinkinga zokuphefumula, kuhlanganise ne-asthma noma i-COPD
  • Isifo noma isifo sezinso
  • I-prostate ekhulisiwe noma izinkinga ngomchamo odlulayo
  • Izimo zempilo yengqondo
  • Izinkinga zokusebenzisa izidakamizwa
  • Ukukhuluphala ngokweqile noma izinkinga zesistimu yokugaya ukudla
• Abadala: Abantu abadala asebekhulile bangase babe nemiphumela enamandla evela kulo muthi, ikakhulukazi ukudideka, isiyezi, nobunzima bokuphefumula. 
• Ukukhulelwa Nokuncelisa: Abesifazane abakhulelwe kufanele basebenzise le mithi kuphela lapho kudingeka ngokucacile, njengoba ingase ilimaze ingane engakazalwa. Komama abancelisayo, umuthi udlulela obisini lwebele futhi ungabangela izinkinga ezifana nalezi:
  • Ubuthongo obungajwayelekile
  • Ukuncelisa ubunzima
  • Izinkinga zokuphuza
  • Ukuxhuga okungajwayelekile kusana oluncelisayo
• Ezinye Izinyathelo Zokuqapha: Iziguli kufanele zigweme ukushayela noma ukusebenzisa imishini. Kubalulekile ukugwema ukuphuza utshwala ngesikhathi sokwelashwa, njengoba kungandisa ingozi yemiphumela emibi kakhulu.

Isebenza kanjani i-Acetaminophen ene-Codeine Tablet

Umuthi usebenza ngalezi zindlela ezibalulekile:

• Ukuguqulwa Kwesignali Yobuhlungu: I-acetaminophen ishintsha indlela umzimba osebenza ngayo izimpawu zobuhlungu futhi isiza ukupholisa umzimba
• I-Central Nervous System Effects: I-Codeine iqondise ngokuqondile ubuchopho nesistimu yezinzwa ukuze kuguqulwe umbono wobuhlungu.
• Ukucindezela Ukukhwehlela: Ngaphezu kokunciphisa ubuhlungu, i-codeine inciphisa umsebenzi esikhungweni sokulawula ukukhwehlela kwengqondo
• I-Temperature Regulation: Ingxenye ye-acetaminophen isiza ukuphatha imfiva ngokuthinta uhlelo lokulawula izinga lokushisa lomzimba.

Uma zihlangene, lezi zingxenye zenza isixazululo esiphumelelayo sokuphatha ubuhlungu. Ingxenye ye-acetaminophen iqala ukusebenza ngokushesha ezinhlungwini nasemfivani, kuyilapho i-codeine inikeza ukukhululeka kobuhlungu okwengeziwe ngemiphumela yayo ezikhungweni zokucubungula izinhlungu zobuchopho.

Ngingathatha I-Acetaminophen ne-Codeine Ngeminye Imithi?

Imithi eminingana evamile ingathinta indlela i-acetaminophen ne-codeine esebenza ngayo emzimbeni. Iziguli kufanele ziqaphele:

• Ama-antihistamine, njenge-cetirizine, i-diphenhydramine
• I-Azole antifungal
• IBupropion
• Izidakamizwa zokukhathazeka nokulala, kuhlanganise ne-alprazolam, i-zolpidem, i-lorazepam
• Ama-antibiotic e-Macrolide afana ne-erythromycin
• Umuthi osetshenziselwa ukwelapha isithuthwane
• Iziphumuli zemisipha, njenge-carisoprodol, i-cyclobenzaparine
• Imithi ephikisana ne-opioid efana ne-samidorphan
• Omunye umuthi wezinhlungu ze-opioid noma ukukhwehlela, njenge-morphine, i-hydrocodone
• I-Rifamycins

Ulwazi lwe-Acetaminophen kanye ne-Codeine Dosage

Kubantu abadala abaneminyaka engu-18-65, umthamo ojwayelekile uhlanganisa:

• I-15 kuya ku-60 mg ye-codeine ehlanganiswe ne-150 kuya ku-600 mg ye-acetaminophen njalo emahoreni angu-4 njengoba kudingeka.
• Isixazululo somlomo: 15 milliliters (mL) njalo emahoreni ama-4 njengoba kudingeka
• Kumaphilisi: 1 noma 2 ithebhulethi njalo emahoreni ama-4 njengoba kudingeka

Umthamo Wezingane: Ezinganeni, umuthi uza ngezindlela ezihlukene nemihlahlandlela ethile yokudosa:

• Iminyaka engu-7 kuya kweyi-12: 10 mL yokumiswa ngomlomo izikhathi ezi-3 noma ezi-4 ngosuku
• Iminyaka engu-3 kuya kweyi-6: 5 mL yokumiswa ngomlomo izikhathi ezi-3 noma ezi-4 ngosuku
• Izingane ezingaphansi kweminyaka emi-3: Umthamo kufanele unqunywe udokotela

Isiphetho

I-acetaminophen ene-codeine ime njengemithi eyinhlanganisela enamandla esiza iziguli ukuphatha ubuhlungu obumaphakathi kuya kobunzima ngokusebenzisa indlela yayo yezenzo ezimbili. Umuthi udinga ukunakwa ngokucophelela emiyalweni yomthamo, imihlahlandlela yokuphepha, kanye nemiphumela engemihle engaba khona ukuze uthole imiphumela emihle.

Iziguli kufanele zikhumbule ukuthi ukulawulwa kobuhlungu okuphumelelayo ngalo muthi kuncike ekukhulumeni okuvulekile nodokotela kanye nokunamathela ngokuqinile emithini enqunyiwe. Ukuqapha njalo kusiza ukuqinisekisa ukusebenza komuthi ngenkathi kugcinwa ukuphepha. Nakuba imithi inezingozi zemiphumela engemihle kanye nokuncika okungaba khona, lokhu akufanele kuvimbele ukwelashwa okufanele uma kushiwo ngendlela efanele.

Odokotela basebenza njengabalingani ababalulekile ekulawuleni ubuhlungu ngalo muthi. Umhlahlandlela wabo usiza iziguli ukuthi zisebenzise indlela efanele, ziqaphe imiphumela emibi engaba khona, futhi zilungise izinhlelo zokwelashwa njengoba kudingeka. Impumelelo nge-acetaminophen ne-codeine ivela ekuqondeni kokubili izinzuzo nezingozi zayo kuyilapho ulandela isiqondiso sezokwelapha ngokucophelela.

Imibuzo Evame Ukubuzwa

1. Ingabe i-acetaminophen ene-codeine inamandla?

Ucwaningo lubonisa ukuthi i-acetaminophen ene-codeine inikeza ukukhululeka kobuhlungu okunamandla uma kuqhathaniswa ne-acetaminophen iyodwa. Kodwa-ke, ucwaningo lubonisa ukuthi i-codeine ngokwayo ingase ingasebenzi kangcono kune-placebo yokukhulula ubuhlungu. Inhlanganisela isebenza kangcono ngoba ihlose ubuhlungu ngokusebenzisa izindlela ezahlukene.

2. Yiziphi izinyathelo zokuphepha ezikhethekile okufanele ngizilandele?

Ngaphambi kokuqala le mithi, iziguli kufanele zazise udokotela wazo mayelana nanoma yikuphi ukungezwani komzimba ne-acetaminophen, codeine, noma eminye imithi. Izinyathelo ezibalulekile zokuphepha zihlanganisa:

• Ukwazisa odokotela ngayo yonke imithi yamanje
• Ukuxoxa nganoma yimuphi umlando wesifo sesibindi
• Gwema utshwala nensangu
• Ebala izinhlelo zokukhulelwa noma zokuncelisa

3. Yini okufanele ngiyenze uma ngikhohlwa umthamo?

Uma uphuthelwa umthamo, thatha umthamo ogejiwe ngokushesha njengoba ukhumbula. Kodwa-ke, uma cishe sekuyisikhathi somuthi wakho ohleliwe olandelayo, yeqa ogejiwe futhi uqhubeke neshejuli evamile.

4. Yini okufanele ngiyazi mayelana nokugcinwa nokulahlwa kwalo muthi?

Gcina umuthi ebhokisini lawo langempela ekamelweni lokushisa, kude nomswakama nokushisa. Okokulahla:

• Sebenzisa izindawo zokuthatha izidakamizwa uma zikhona
• Cabangela ukusebenzisa izimvilophu ze-imeyili ezikhokhelwa kusengaphambili zezidakamizwa
• Landela imihlahlandlela ye-FDA ukuze ulahlwe ngendlela efanele
• Gcina imithi lapho izingane zingakwazi ukufinyelela khona