I-Cefixime

I-Cefixime

I-Cefixime iyi-antibiotic esetshenziselwa izinhlobo eziningi zezifo ezibangelwa amagciwane. Isetshenziselwa ukwelapha izifo zebhaktheriya ezinzima (zesikhashana) ezifana nezifo ezindlebeni, izifo zesifuba nomphimbo, kanye nezifo zomgudu womchamo. Ngokuqeda ama-microorganisms ayi-causative, i-Cefixime isiza ukukhulula lezi zifo.

Kuye ngesimo esiphathwayo, umthamo uyanqunywa. Qinisekisa ukuthi udokotela wakho uyazi nganoma yikuphi ukusabela okubi okudlule okungenzeka ube nakho nganoma imaphi amanye ama-antibiotic. 

Isebenza kanjani i-Cefixime?

I-Cefixime isebenza ngokuphazamisa ukukhula nokukhiqizwa kwamagciwane. Lokhu ikwenza ngokuvimbela ukwakheka kodonga lweseli yebhaktheriya, yenza amabhaktheriya abe buthaka, futhi ekugcineni aholele ekubhujisweni kwawo. Le ndlela yokusebenza yenza i-Cefixime iphumelele ekulweni namagciwane ahlukahlukene amagciwane.

Indlela Yokusebenza

I-Cefixime iyi-antibiotic engokwesigaba semithi eyaziwa ngokuthi i-cephalosporins. Indlela yayo yokusebenza ibandakanya ukuvimbela ukwakheka kwezindonga zamaseli ebhaktheriya. Ngokukhethekile, i-Cefixime iphazamisa isinyathelo sokugcina sokwakheka kodonga lwamaseli ebhaktheriya ngokubophezela kumaprotheni athile abizwa ngokuthi ama-penicillin-binding proteins (PBPs) atholakala kulwelwesi lwamaseli ebhaktheriya. Lokhu kubophezela kuvimbela ukuxhumanisa kwamaketanga e-peptidoglycan, okuyizingxenye ezibalulekile zodonga lweseli yebhaktheriya. Ngenxa yalokho, amabhaktheriya awakwazi ukwakha nokugcina izindonga zamangqamuzana ngendlela efanele, okuholela ezenzweni zamangqamuzana ezibuthakathaka kanye nokufa kwamangqamuzana ekugcineni.

I-Cefixime iyasebenza ngokumelene ne-spectrum ebanzi yamagciwane ngokukhomba kokubili i-Gram-positive kanye ne-Gram-negative organisms. Isenzo sayo se-bactericidal sikwenza kube usizo ekwelapheni izifo ezihlukahlukene zamagciwane, kuhlanganise nezifo zemigudu yokuphefumula, ukutheleleka kwe-urinary tract, nezinye izifo ezithathelwana ngocansi, phakathi kokunye.

Yiziphi izici zokusetshenziswa kwe-Cefixime?

Izinhlobo eziningi ezahlukene zezifo ezibangelwa amagciwane zelashwa nge-Cefixime. Lesi sidakamizwa sibizwa ngokuthi i-Cephalosporin. Isebenza ngokuvimbela amagciwane ayingozi ekukhuleni. Izifo ezibangelwa amagciwane kuphela zisabela kahle kulo muthi. Ayisebenzi ekulweni nezifo ezibangelwa amagciwane (njengomkhuhlane ovamile, umkhuhlane njll.). Ingasetshenziswa ekwelapheni i-bronchitis, i-gonorrhoea, izifo ezindlebeni, emphinjeni, amalaka, kanye nomgudu womchamo. 

Ungayithatha kanjani futhi nini i-Cefixime?

Thatha lesi sidakamizwa ngomlomo njengoba kunqunywe udokotela wakho, ngokuvamile kanye ngosuku, ngokudla noma ngaphandle kokudla. Uma uthatha amaphilisi ahlafunwayo, wahlafune ngokuphelele ngaphambi kokuwagwinya. Umthamo uhlale unqunywa udokotela wakho kuye ngesimo sakho sempilo, isisindo, kanye nempendulo yokwelashwa. Ukuze uthole imiphumela engcono kakhulu kule mithi elwa namagciwane thatha lo muthi ngokwencwadi kadokotela.

Isikhungo sayo yonke ithebhulethi ye-Cefixime inomugqa ogijima kuyo. Uma udokotela wakho ekutshela ukuthi uphuze ingxenye yephilisi kuphela, yephule kancane emugqeni. Londoloza ingxenye esele yethebhulethi ukuze uthole umthamo wakho olandelayo njengoba uyalelwe. Ngisho noma izimpawu ziphela ngemva kwezinsuku ezimbalwa, qhubeka uthatha lo muthi kuze kube yilapho wonke umthamo oyaliwe usuphelile. Uma uyeka ukuphuza umuthi ngokushesha, amagciwane angase akwazi ukuqhubeka nokukhula futhi abangele ukuthi ukutheleleka kubuye.

Okunye ukusetshenziswa - I-Cefixime nayo isetshenziswa ngezikhathi ezithile ukwelapha Inyumoniya, Shigella (isifo esibangela isifo sohudo esibi kakhulu), kanye ne-Typhoid fever (isifo esiyingozi esivamile emazweni asathuthuka) kulabo abangazwani ne-penicillin. Izingozi zokusebenzisa lo muthi ekuguleni kwakho kufanele kuxoxwe ngazo nodokotela wakho. Buza udokotela wakho noma usokhemisi ngemininingwane eyengeziwe uma ukholelwa ukuthi lesi sidakamizwa kufanele sisetshenziselwe enye into.

Isikali

Umthamo ojwayelekile we-Cefixime uyahlukahluka kuye ngeminyaka kanye nohlobo lokutheleleka okwelashwa ngalo:

• Abantu abadala: Imvamisa, kungama-400 mg kanye ngosuku noma kuhlukaniselwe imithamo emibili engu-200 mg nsuku zonke.
• Izingane: Umthamo unqunywa isisindo kanye nobukhulu besifo, ngokuvamile unikezwa kabili ngosuku.

Iyini imiphumela emibi ye-Cefixime?

Uma unezinye zalezi zimpawu ezilandelayo zokungezwani komzimba ne-Cefixime: Isifuba, Ukuvuvukala kobuso, izindebe, noma umphimbo, Izinkinga zokuphefumula, funa usizo lwezokwelapha ngokushesha. Shayela udokotela wakho uma unesinye salezi zimpawu ezilandelayo:

• jaundice
• Seizure
• Ubuhlungu obukhulu besisu, isifo sohudo esinegazi noma esimanzi.
• Umchamo onombala omnyama noma ibala eliphuzi, ukudideka, noma ubuthakathaka.
• Ukuncipha kwamangqamuzana egazi kungase kubangele ubuthakathaka obungalindelekile noma ukugula, imfiva, ukugodola, izimpawu ezinjengomkhuhlane, izilonda emlonyeni, nezilonda zesikhumba, kanye nebala eliphaphathekile, ukopha okungavamile, imihuzuko kalula, nesiyezi.
• Ukuqubuka kwesikhumba okubomvu noma okunsomi okusakazeka futhi kukhiphe amabhamuza nokuxebuka kulandelwa ukusabela okunamandla kwesikhumba okuhlanganisa umkhuhlane, umphimbo obuhlungu, ukuvutha emehlweni, nokungakhululeki kwesikhumba.

Ezimweni ezingavamile kakhulu i-cefixime ingase ibangele imiphumela emibi, njenge:

• Ukuzithoba
• Ubuhlungu besisu
• I-nausea nokuhlanza
• Ukuluma noma ukuphuma komchamo.

Kufanele ngithinte nini udokotela ngemiphumela emibi?

Kufanele uxhumane nodokotela wakho uma uhlangabezana nanoma yimiphi imiphumela emibi elandelayo ngenkathi uthatha i-Cefixime:

• Uhudo olunzima, ikakhulukazi uma linamanzi noma linegazi.
• Izimpawu zokungezwani komzimba, njengokuqubuka, ukulunywa, ukuvuvukala (ikakhulukazi ubuso/ulimi/umphimbo), isiyezi esinzima, noma ukuphefumula kanzima.
• Ubuhlungu besisu obuphikelelayo noma obunzima noma ama-cramping.
• Ukuba phuzi kwesikhumba noma amehlo (i-jaundice) noma umchamo omnyama, okungase kubonise izinkinga zesibindi.
• Ukulimala noma ukopha okungajwayelekile.
• Izimpawu zokutheleleka okusha noma ukwanda kokutheleleka okukhona.
• Ukusabela okukhulu kwesikhumba, njengokuqhuma noma ukuxebuka.

Yiziphi izinyathelo zokuphepha okufanele zithathwe?

• Uma uguliswa yi-Cefixime namanye ama-antibiotic e-cephalosporin, noma uma unokuthile okungezwani komzimba wakho, yazisa udokotela wakho ngaphambi kokusebenzisa i-Cefixime.
• Ukugonywa kwe-typhoid neminye imigomo yebhaktheriya ephilayo kungase kusebenze kancane uma kusetshenziswa i-Cefixime. Ngaphambi kokuthola isibhamu noma imithi yokugoma, yazisa udokotela wakho ukuthi uthatha i-Cefixime.
• Inguqulo yalo muthi ehlafunwayo ingaba ne-aspartame kuyo. I-Aspartame kufanele ikhawulelwe noma igwenywe ekudleni kwakho uma une-Phenylketonuria (PKU) noma esinye isimo esiphathelene nesimo. Bonana nodokotela wakho noma usokhemisi ukuze uthole iseluleko sokuthi ungawusebenzisa kanjani lo muthi ngokuphepha uma unanoma iyiphi yalezi zimo.
• I-Cefixime ingase ibangele isifo sohudo, futhi lesi sifo singase sibe sibi kakhulu ngezikhathi ezithile. Ungalokothi unikeze ingane yakho umuthi noma uphuze noma yimuphi umuthi wohudo ngaphandle kokubonana nodokotela kuqala.
• Uma ukhona okhulelwe noma oncelisayo ke sicela wazise udokotela wakho ngaphambi kokuthatha lo muthi.

Kuthiwani uma ngiphuthelwe umthamo we-Cefixime?

Thatha umthamo we-Cefixime ongekho ngokushesha nje lapho ukhumbula. Uma umthamo wakho olandelayo ohleliwe usondela, yeqa umthamo ongekho. Ungathathi imithi eyengeziwe ukulungisa umthamo ongekho. Xhumana nodokotela wakho uma udidekile futhi uthole ukucaciseleka ngalokho okufanele ukwenze uma kwenzeka ungekho umthamo.

Kuthiwani uma kune-overdose ye-Cefixime?

Shayela usizo ngokushesha uma othile ephuze ngokweqile futhi enezimpawu ezinzima njengokuquleka noma ukuphefumula kanzima. Finyelela esibhedlela esiseduze uma kwenzeka ukweqisa umthamo.

Yiziphi izimo zokugcina nokulahlwa kwe-Cefixime?

Gcina lo muthi uvalwe ngokuqinile esitsheni sokuqala, kude nezingane, futhi kude nezilwane ezifuywayo. Gcina amaphilisi, amaphilisi ahlafunwayo, namaphilisi endaweni yokushisa evamile, kude nemithombo yokushisa okukhulu, nasendaweni eyomile. Gcina imithi ewuketshezi ihlanganiswe ngokuqinile futhi ekamelweni lokushisa noma efrijini; ngemva kwezinsuku eziyi-14, lahla noma yiziphi ezisasebenziseka.

Ukuze uvimbele izinja, izingane, nabanye abantu ukuthi bangadli imithi esele, kufanele ilahlwe ngendlela ethile. Lomuthi akufanele, nokho, ulahlwe phansi endlini yangasese. Ukuze ugcine izingane ezincane ziphephile ekufakweni ushevu, vala amakepisi okuphepha ngaso sonke isikhathi futhi ngokushesha ugcine imithi endaweni ephephile lapho bengayiboni futhi bangafinyeleli kuyo.

Ukusebenzisana kwe-Cefixime Neminye Imithi

Yazisa udokotela wakho ngayo yonke imithi oyisebenzisayo, okuhlanganisa amavithamini, izithasiselo zemithi, incwadi kadokotela, kanye nezidakamizwa ezingabhalwanga. Yazisa udokotela wakho ngokushesha uma uthatha: 

• I-Carbamazepine 
• Ama-Anticoagulants afana ne-heparin ne-warfarin
• Amaphilisi okulawula ukuzala
• I-Probenecid (Probalan, Benemid)
• I-Methotrexate (i-Trexall, i-Rheumatrex)

Okunye Ukusebenzisana

Eminye imithi akufanele iphuzwe kanye noma ngokushesha ngemva kokudla ukudla noma izinhlobo ezithile zokudla, njengoba lokhu kungaholela ekusebenzisaneni. Ngokufanayo, ukuphuza utshwala noma ugwayi ngenkathi uthatha imithi ethile nakho kungase kubangele ukusebenzisana. Kubalulekile ukukhuluma nomhlinzeki wakho wokunakekelwa kwezempilo mayelana nokuthi kufanele yini uphuze imithi yakho nokudla, utshwala, noma ugwayi ukuze ugweme izinkinga ezingase zibe khona noma ukunciphisa ukusebenza kahle.

I-Cefixime ibonisa ngokushesha kangakanani imiphumela?

Imiphumela yomuthi i-Cefixime ivamise ukuqala phakathi kwemizuzu eyi-10 nengama-30 ngemuva kokuphathwa kwawo. Kuncike ngokuphelele ekuphenduleni komuntu ngokwebhayoloji kanye namakhemikhali omzimba.

Yini okufanele ngimazise udokotela ngaphambi kokuthatha umuthi?

Ngaphambi kokuqala i-Cefixime, tshela udokotela wakho:

• Uma unezinkinga zempilo, njengezinkinga zezinso noma ukungezwani komzimba kuma-antibiotics.
• Mayelana nanoma yikuphi ukungezwani komzimba nakho, ikakhulukazi kuma-antibiotics afana ne-cephalosporins noma ama-penicillin.
• Uma ukhulelwe, uhlela ukukhulelwa, noma ukuncelisa.
• Yonke imithi oyiphuzayo njengamanje, okuhlanganisa amavithamini nezithako zokudla.
• Uma uke waba nezinkinga ngama-antibiotics esikhathini esidlule.
• Noma yiziphi izinguquko ezinkulu ekudleni kwakho noma uma unemikhawulo yokudla.
• Uma unezimpawu zokutheleleka, ngakho udokotela wakho anganquma ukuthi i-Cefixime ifanele yini isimo sakho.

Ukuqhathaniswa kwe-Cefixime ne-Amoxicillin