I-Diclofenac

I-Diclofenac

I-Diclofenac iyisidakamizwa esingeyona i-steroidal anti-inflammatory (NSAID). Kuhloswe ukukhulula ubuhlungu nokunciphisa ukuvuvukala ngokuqeda imbangela noma izici ezibangela ubuhlungu emzimbeni. Ingajovwa ngomlomo, nge-intravenously (ngaphakathi emithanjeni), nge-rectally (nge-rectum), noma ngaphansi kwesikhumba (ngesikhumba). Isebenza ngokuvimbela i-enzyme ye-prostaglandin, okuyisizathu sobuhlungu nokuvuvukala.

Ake sifinyelele kuzo zonke izici ezihlobene ne-Diclofenac.

Yiziphi izici zokusetshenziswa kwe-Diclofenac?

Isiza ekudambiseni ukuvuvukala (ukuvuvukala), ubuhlungu, nokuqina kwamalunga (amalunga anganyakazi) okubangwa yinoma yimaphi uhlobo lwe-arthritis. Umuthi usetshenziselwa ukwelapha ubuhlungu obuncane kuya kobumaphakathi kanye nezimpawu nezimpawu ze-rheumatoid arthritis (isifo esithinta amalunga amancane) kanye ne-osteoarthritis (isifo esithinta amalunga amade).

Isetshenziselwa ukwelapha i-ankylosis spondylitis (ukuvuvukala komgogodla). Ukuqeda lezi zimpawu kungasiza ukuthuthukisa izinga lempilo yeziguli.

Kodwa-ke, ngaphambi kokuthatha lesi sidakamizwa ngezimo ezingapheli (isikhathi eside) njenge-arthritis, iziguli kufanele zithintane nodokotela.

Ungayithatha kanjani futhi nini i-Diclofenac?

Kunqunyelwe ukuphatha ubuhlungu obuhlala isikhathi eside nobungabekezeleleki okwenzeka ngenxa yezimo ezifana ne-arthritis, amajaqamba okuya esikhathini, i-migraines, njll.  

I-Diclofenac ilawulwa ngezindlela ezihlukahlukene, kodwa indlela evamile yokuyithatha ngomlomo, noma ngomlomo. Umuthi uza ngezindlela ezahlukahlukene njengamaphilisi agcwele uketshezi, amaphilisi, amaphilisi e-gelatin aqinile, nezimpushana ukuze uphuzwe ngomlomo.

Ama-capsules e-diclofenac agcwele uketshezi ngokuvamile athathwa izikhathi ezingu-4 ngosuku, kuyilapho ama-gelatin capsules aqinile athathwa izikhathi ezi-3 ngosuku esiswini esingenalutho. Amaphilisi e-Diclofenac athathwa kanye ngosuku, kodwa amaphilisi ama-2 ngosuku anqunyelwe ezimweni ezinzima. Ngekhanda le-migraine, umthamo owodwa wesisombululo se-diclofenac powder unconywa ngaphandle kokudla. Iziguli kufanele ziphuze umuthi ngesikhathi esifanayo nsuku zonke uma zelulekwa ukuthi ziwuphuze njalo.

Iyini imiphumela emibi ye-Diclofenac?

I-Diclofenac ingabonisa izimpawu zokungezwani okuhlukahlukene, njengobunzima bokuphefumula, ukuvuvukala kobuso nomphimbo, noma ukusabela okunzima kwesikhumba (ubuhlungu besikhumba, amabhamuza, ukuxebuka, nokuqubuka kwesikhumba). Yeka ukusebenzisa i-diclofenac noma ufune usizo lwezokwelapha ezimeni ezinzima ezifana nokuba ndikindiki kungazelelwe, ubuhlungu besifuba, ubuhlungu bemisipha, ukuvuvuka kwezindlala, njll.

 Uma isiguli sinesinye salezi zimpawu ezilandelayo, thintana nodokotela ngokushesha futhi uyeke ukusebenzisa umuthi.

• Izimpawu zokuqubuka kwesikhumba (okuncane noma okumaphakathi)

• Izimpawu ezinjenge-flu

• Izinkinga zenhliziyo: ukuphefumula, ukuzuza kwesisindo ngokushesha

• Izinkinga zezinso: ukuchama okuncane noma ukungachami, ukuphuma komchamo okubuhlungu, ukuvuvukala kwemilenze nezingalo.

• Izinkinga zesibindi: ubuhlungu besisu, isifo sohudo, i-jaundice

 Eminye imiphumela emibi evamile yomuthi ihlanganisa:

• Ukuqunjelwa, igesi, nesicanucanu

• ukuqunjelwa

• Ukozela, ikhanda

• Ukujuluka, ukulunywa

• Umfutho wegazi ophezulu

Yiziphi izinyathelo zokuphepha okufanele zithathwe ngaphambi kokuthatha i-Diclofenac?

Ngaphambi kokuthatha lesi sidakamizwa, iziguli kufanele zikhumbule amaphuzu alandelayo:

• Isiguli kufanele sitshele udokotela uma singezwani ne-diclofenac, aspirin, NSAIDs (naproxen, ibuprofen, celecoxib) nanoma yiziphi ezinye izidakamizwa.

• Yazisa udokotela ngomlando wezokwelapha, ikakhulukazi: isifuba somoya (ukuba nomlando wokuphelelwa umoya ngemva kokuthatha ama-NSAID noma i-aspirin), izinkinga zokumanyana noma ukopha, izinkinga zenhliziyo (njengokuhlasela kwenhliziyo kwangaphambilini), isifo sesibindi, ama-polyps akhala, izinkinga zamathumbu noma zesisu.

• Ingabangela ukulimala kwezinso uma isetshenziswa isikhathi eside. Esimeni sanoma yiziphi izinkinga zezinso ezikhona, amathuba okwehluleka kwezinso angakhula ngokusetshenziswa kwe-diclofenac.

• Yazisa udokotela mayelana nokuhlinzwa kwangaphambilini kanye nemiyalelo yezidakamizwa.

• Ungashayeli ngemva kokudla lesi sidakamizwa ngoba singabangela isiyezi kanye nobuthongo.

• Kungabangela ukopha esiswini, futhi ingozi ingakhula ngokusetshenziswa kukagwayi notshwala.

• Abantu abadala basengozini enkulu yokopha emathunjini nasesiswini, isifo senhliziyo, kanye nokushaywa unhlangothi lapho udla lesi sidakamizwa.

• Uma unomfutho wegazi ophakeme noma ugcina amanzi, kubalulekile ukwazisa udokotela wakho ngaphambi kokuqala i-diclofenac. Ukwengeza i-NSAID ohlelweni lwakho kungase kubeke umthwalo owengeziwe enhliziyweni yakho, ikakhulukazi uma isivele isebenza kanzima.

• Uma uke waba nesilonda ngaphambili noma ukopha emathunjini, kuhle ukuthi uthintane nodokotela wakho ngaphambi kokusebenzisa i-diclofenac, njengoba ingozi yakho yesinye isiqephu sokopha iphakeme.

• Kubantu abanezinkinga zezinso noma labo abasebenzisa i-diuretics (amaphilisi amanzi), ukusetshenziswa kwe-diclofenac kungase kuthinte ikhono lezinso lokukhipha uketshezi oluningi. Xoxa nomhlinzeki wakho wokunakekelwa kwezempilo ukuthi i-diclofenac ifanele yini isimo sakho.

• Uma unesifuba somoya futhi uzwela ku-aspirin, kunethuba lokusabela okunzima ku-diclofenac. Ngaphambi kokusebenzisa lo muthi, kubalulekile ukuba nengxoxo nodokotela wakho.

Kuthiwani uma ngiphuthelwe umthamo we-Diclofenac?

Uma uphuthelwa ukuthatha umthamo we-diclofenac, kufanele uthathe le thebhulethi ngokushesha nje lapho ukhumbula. Uma kuyisikhathi somthamo olandelayo, khona-ke kuyalulekwa ukuthi weqe umthamo ogejiwe futhi uthathe umthamo ojwayelekile njengoba uhleliwe.

Akufanele uthathe umthamo owengeziwe ukuze uvale umthamo okhohliwe. Setha i-alamu yesikhumbuzi ukuze ungakhohlwa ukuphuza umuthi wakho ngesikhathi. 

Kuthiwani uma ngidlula i-Diclofenac?

Iziguli ziphakanyiswa ukuthi zingasebenzisi amanani eqile ale thebhulethi. Ukweqisa kuthebhulethi ye-diclofenac kungabangela ubuthi neminye imiphumela emibi kakhulu. Futhi, imiphumela emibi kanye nezimpawu zalokhu kweqisa akukwazi ukushintshwa ngokuphuza imithi eminingi. Yabelana ngolwazi oluningiliziwe mayelana nokusebenzisa ngokweqile ukuze odokotela basize isiguli sinciphise izimpawu nemiphumela engemihle.

Yiziphi izimo zokugcina i-Diclofenac?

Yonke imithi kufanele igcinwe ekamelweni lokushisa futhi igcinwe kude nokushisa okuqondile nokukhanya ukuze ivikeleke ukuthi yonakale. Ungagcini imithi eziqandisini. Ungalinge ulahle le mithi kuma-drainage systems noma uyishaye ezindlini zokugeza. Abantu bangathintana nodokotela noma osokhemisi ukuze bazi ukuthi yini okufanele bayigcine nokuthi bayilahle nini imithi.

Ngingakwazi ukuthatha i-Diclofenac neminye imithi?

Iziguli zingathatha i-diclofenac nge-codeine noma i-paracetamol. Kodwa-ke, kufanele igwenywe ngamaphilisi ezinhlungu afana ne-naproxen, ibuprofen, ne-aspirin. Nakuba lawa maphilisi ezinhlungu angokwesigaba esifanayo sezidakamizwa ze-NSAID njenge-diclofenac, angabangela ubuhlungu besisu, ikhanda elibuhlungu, njll.

Uma kufanele uphuze le mithi nanoma yimiphi eminye, thintana nodokotela kuqala. 

I-Diclofenac izobonisa ngokushesha kangakanani imiphumela?

Amaphilisi noma amaphilisi e-Diclofenac athatha imizuzu engama-20 kuya kwengama-30 ukusebenza. Kuthatha amahora ambalwa ukuthi ama-suppositories abonise imiphumela. Awukho umehluko endleleni ama-suppositories, amaphilisi, namaphilisi asebenza ngayo. Umthamo womuthi ngamunye mncane.

I-Diclofenac vs Aceclofenac

Kokubili i-aceclofenac ne-diclofenac yizidakamizwa ezingezona ukuvuvukala (ama-NSAID). Iziguli ezinezifo ezivuthayo ze-rheumatic kanye ne-non-rheumatic zinqunywe amaphilisi e-diclofenac. Amaphilisi e-Aceclofenac anikeza ukukhululeka kwezimpawu ezimweni ezibuhlungu ezifana nobuhlungu obuhlangene.

Isiphetho

I-Diclofenac ingenye yezidakamizwa ezisetshenziswa kakhulu zokudambisa izinhlungu ezibangelwa isifo samathambo. Amanani alinganiselwe e-diclofenac aphephile futhi ayasebenza. Nokho, amanani eqile angabangela izinkinga ezinkulu. Ngakho-ke, iseluleko sochwepheshe siyadingeka ngaphambi kokuthatha lo muthi. 

Imibuzo Evame Ukubuzwa

1. Iyiphi i-diclofenac esetshenziselwa kangcono?

I-Diclofenac ivame ukusetshenziselwa ukudambisa izinhlungu, ukunciphisa ukuvuvukala, nokulawula izimo ezinjenge-arthritis, ubuhlungu bamalunga, ubuhlungu bemisipha, namajaqamba okuya esikhathini. Ibuye isetshenziselwe ukwelapha ukuhlaselwa kwe-migraine acute.

2. Ingabe i-diclofenac iyisidambisa-zinhlungu esihle?

Yebo, i-diclofenac ibhekwa njengesidambisa-zinhlungu esisebenzayo kanye nemithi elwa nokuvuvukala. Inganikeza ukukhululeka ezinhlotsheni ezihlukahlukene zobuhlungu, ikakhulukazi uma ukuvuvukala kuyisici esibangela.

3. Ingabe i-diclofenac ingasetshenziselwa ubuhlungu bekhanda?

Yebo, i-diclofenac ingasetshenziswa ekudambiseni ubuhlungu bekhanda, kuhlanganise nemigraines. Itholakala ekuhlanganiseni okuhlukahlukene, okuhlanganisa amaphilisi nemijovo, yokwelapha ukuhlaselwa kwe-migraine acute.

4. Uyini umehluko phakathi kwe-Diclofenac ne-Aceclofenac?

I-Diclofenac ne-aceclofenac zombili izidakamizwa ezilwa nokuvuvukala (ama-NSAID) ezinokusetshenziswa okufanayo, kodwa kunomehluko. I-Aceclofenac ithathwa njengokuphuma kwe-diclofenac. Nakuba kokubili kusetshenziselwa ubuhlungu nokuvuvukala, i-aceclofenac ivame ukubhekwa njengephrofayili engcono yokuphepha emathunjini. Ukukhetha phakathi kwabo kufanele kwenziwe ngokusekelwe ezicini zomuntu ngamunye kanye nezincomo zomhlinzeki wezempilo.

5. Ingabe i-diclofenac iphephile ukuyisebenzisa ngesikhathi sokukhulelwa?

I-Diclofenac ngokuvamile ayinconywa ngesikhathi sokukhulelwa, ikakhulukazi ku-trimester yesithathu, njengoba ingase ibe nemiphumela emibi kumntwana okhulayo. Kubalulekile ukuthintana nomhlinzeki wezempilo ukuze uhlole ezinye izindlela eziphephile zokuqeda izinhlungu ngesikhathi sokukhulelwa.

References:

https://www.drugs.com/diclofenac.html https://medlineplus.gov/druginfo/meds/a689002.html https://www.nhs.uk/medicines/diclofenac/

Umshwana wokuzihlangula: Ulwazi olunikezwe lapha alwenzelwe ukufaka iseluleko esivela kuchwepheshe wezokunakekelwa kwempilo. Ulwazi aluhloselwe ukumboza konke ukusetshenziswa okungenzeka, imiphumela engemihle, izinyathelo zokuphepha, nokusebenzisana kwezidakamizwa. Lolu lwazi aluhloselwe ukuphakamisa ukuthi ukusebenzisa umuthi othile kufanelekile, kuphephile, noma kuyasebenza wena noma omunye umuntu. Ukungabi bikho kwanoma yiluphi ulwazi noma isexwayiso mayelana nomuthi akufanele kuhunyushwe njengesiqinisekiso esicacile esivela enhlanganweni. Sikweluleka ngokuqinile ukuthi uthintane nodokotela uma kukhona okukukhathazayo ngomuthi futhi ungalokothi usebenzise umuthi ngaphandle kwencwadi kadokotela.