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I-Doxofylline

I-Doxofylline isebenza njenge-bronchodilator enamandla ethuthukisa ukusebenza kwamaphaphu ezigulini ezinezimo zokuphefumula kakhulu futhi ikhuphule umthamo wokuphefumula ophoqelekile. Lo muthi uhlukile kweminye i-xanthines ngoba ayinakho ukuhlobana okuningi kwama-adenosine receptors futhi ayikhiqizi imiphumela evuselelayo. Odokotela basebenzisa le phosphodiesterase inhibitor ukwelapha izifo ezingapheli zokuphefumula njenge ufuba futhi COPD. Le ndatshana ihlanganisa yonke into nge-doxofylline—kusukela ekusetshenzisweni kwayo nasekuthatheni ngendlela efanele kuya emiphumeleni engemihle kanye nokusebenza kwayo emzimbeni. 

Iyini i-Doxofylline?

I-Doxofylline umuthi we-bronchodilator ongowomndeni ophuma ku-xanthine. Lo muthi ungawuthola kufomu lethebhulethi elisebenza ohlelweni lokuphefumula. Iphrofayili yokuphepha ye-Doxofylline idlula eminye imithi efanayo. Nakuba inokwakheka okuhlukile kwezemithi kune-theophylline, iletha imiphumela eqhathanisekayo nokubekezelela isiguli okungcono. Ucwaningo luveze ukuthi ukwelashwa kwe-doxofylline kunciphisa ukusabela okungekuhle futhi kwehlisa nemicimbi yesifuba somoya.

Ukusetshenziswa kwethebhulethi ye-Doxofylline

Odokotela basebenzisa amaphilisi e-doxofylline ukwelapha izimo ezingapheli zokuphefumula. Umuthi usiza iziguli:

Isetshenziswa Kanjani Futhi Nini Ithebhu ye-Doxofylline 

  • Udokotela wakho uzokunikeza umthamo ofanele wamaphilisi e-doxofylline. 
  • Kufanele uphuze la maphilisi ngamanzi ngemva kokudla ukuze ugweme ukucasuka kwesisu. 
  • Ukuvama okudingeka uwuphuze lo muthi kuncike ekutheni isimo sakho sibucayi kangakanani nokuthi usabela kanjani ohlelweni lokwelapha.

Imiphumela Eseceleni Yethebhulethi ye-Doxofylline

Yize i-doxofylline ingumuthi obekezelelwa kahle, ingabangela imiphumela engemihle. Lokhu kubandakanya:

Ukuqapha

  • Tshela udokotela wakho nganoma yiziphi izimo zezokwelapha onazo ngaphambi kokuthatha i-doxofylline.
  • Yazisa udokotela wakho mayelana nezinkinga zenhliziyo eziqhubekayo, isifo sesibindi noma sezinso, kanye ukuphazamiseka kwe-yegilo. 
  • Omama abakhulelwe noma abancelisayo kufanele babuze odokotela babo mayelana nokuphepha. 
  • Utshwala bungenza imiphumela emibi ibe mibi kakhulu, ngakho-ke igweme ngesikhathi sokwelashwa.

Isebenza kanjani iDoxofylline Tablets

I-Doxofylline isebenza ngokuhlukile kweminye imithi efanayo. Isebenza ngokuvimbela ukuwohloka kwe-cAMP, into esiza ukugcina izindlela zomoya zivulekile. Ngokungafani nezinye izidakamizwa ezifana nayo, inomphumela omncane kuma-adenosine receptors, ngakho iphephile futhi ibangela imiphumela emibi embalwa. Ukwengeza, ingase isebenze nama-beta-2 receptors ukusiza imigudu yakho yomoya ikhululeke.

Ngingakwazi ukuthatha i-Doxofylline Neminye Imithi?

I-Doxofylline inomkhawulo emithini efanayo ngoba ayihlangani nama-enzyme esibindi. Kodwa-ke, eminye imithi ingashintsha amazinga e-doxofylline emzimbeni wakho:

Kufanele ugweme ukuphuza i-caffeine ngenkathi uthatha lo muthi.

Ulwazi Lomthamo

Odokotela bavame ukunikeza i-400 mg kabili noma kathathu ngosuku kubantu abadala, ngomkhawulo wansuku zonke we-1,200 mg. Iziguli esezikhulile zidinga imithamo ephansi engu-200 mg kabili noma kathathu ngosuku. Umuthi uthatha cishe izinsuku ezi-4 ukuze ufinyelele amazinga aqinile emzimbeni wakho futhi uqhubeka nokusebenza amahora angama-7-10. Ungathatha i-doxofylline ngokudla noma ngaphandle kokudla, kodwa ukuyiphuza ngemva kokudla kungase kusize ukuvimbela ukucasuka kwesisu.

Isiphetho

I-Doxofylline nakanjani igqama njengenketho enhle yokwelapha uma ulwa nezinkinga zokuphefumula. Lo muthi usebenza kangcono kunezidakamizwa ezifanayo ngenxa yesakhiwo samakhemikhali esiyingqayizivele. Abantu bathanda ukuthi ivula kanjani imigudu yabo yokuphefumula futhi ibangele imiphumela emibi embalwa kunezinye izinketho ezifana ne-theophylline. Umuthi ukhahlela ngokushesha futhi usiza ukuthi uphefumule kalula kuze kufike emahoreni ayi-10 usuku lonke.

I-Doxofylline ingaba impendulo yakho uma isifuba somoya, i-COPD noma ezinye izinkinga zokuphefumula zikuthinta. Ucwaningo lukhombisa ukuthi ithuthukisa kakhulu ukusebenza kwamaphaphu ngenkathi ihlala iphephile ukusetshenziswa kwansuku zonke. Ingxoxo esheshayo nodokotela wakho izokusiza wazi ukuthi lo muthi ukulungele yini futhi uphefumule kalula.

Imibuzo Evame Ukubuzwa

1. Ingabe i-doxofylline iwumuthi onobungozi obukhulu?

I-Doxofylline inephrofayili yokuphepha engcono kuneminye imithi efana ne-theophylline. Ucwaningo lukhombisa ukuthi idala imiphumela engemihle embalwa ngenkathi isebenza nayo. Umuthi awuthinti ukungena kwe-calcium noma uvimbe iziteshi ze-calcium, okuchaza ukuthi kungani ubangela ukusabela okuhlobene nenhliziyo okumbalwa. Ucwaningo olukhulu kakhulu lwe-longitudinal lubonisa iziguli zikubekezelela kahle ngesikhathi sokwelashwa kwesifuba somoya isikhathi eside.

2. Ikuphi ukusetshenziswa okuyinhloko kwethebhulethi ye-doxofylline?

Ukusetshenziswa okuyinhloko kuhlanganisa:

  • Isifuba somoya
  • Izifo Eziphuthumayo Zokuvimbela Izifo (COPD)
  • I-bronchitis enezingxenye ze-spastic

3. Yisiphi isikhathi esingcono kakhulu sokuphuza i-doxofylline ekuseni noma kusihlwa?

Umuthi usebenza kangcono uma uphuzwa kusihlwa ngemva kokudla. Lokhu kusiza ukugcina amazinga egazi eqinile ubusuku bonke. Ihora eliqondile libalulekile kunokulithatha ngesikhathi esifanayo usuku ngalunye.

4. Athatha isikhathi esingakanani ukuthi amaphilisi e-doxofylline asebenze?

Uzobona umuthi uqala ukusebenza cishe imizuzu engama-30 kuya kwengama-60 ngemuva kokuwuphuza. Imigudu yakho yokuphefumula izokhululeka, futhi kuzoba lula ukuphefumula. Izinzuzo ezigcwele zakha ngemva kwezinsuku ezimbalwa zokusetshenziswa okuvamile.

5. Kwenzekani uma ngiphuthelwa umthamo?

Thatha imithi ngokushesha nje lapho ukhumbula. Yeqa umthamo ogejiwe uma kuseduze nesikhathi sakho esilandelayo. Landela inqubo yakho evamile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.

6. Ingabe i-doxofylline iphephile ezinso?

Abantu abanenkinga yezinso badinga ukuqashwa ngokucophelela. Udokotela wakho angase alungise umthamo wakho ngokusekelwe ekusebenzeni kwezinso. 

7. Kwenzekani uma ngiphuza ngokweqile?

I-overdose ingabangela ukushaya kwenhliziyo okungajwayelekile okuyingozi futhi ukuhlukunyezwa. Ezinye izimpawu zihlanganisa isicanucanu, ukuhlanza, ukopha emgudwini wokugaya ukudla, kanye umfutho wegazi ophansi. Thola usizo lwezempilo oluphuthumayo ngokushesha.

8. Ubani ongakwazi ukuthatha i-doxofylline?

Akufanele uthathe lo muthi uma:

  • Yiba nokungezwani nezithako zayo
  • Kwakamuva isifo senhliziyo
  • Yiba nomfutho wegazi ophansi
  •  Bancelisa ingane

9. Zingaki izinsuku zokuphuza ithebhulethi ye-doxofylline?

Ubunzima besimo sakho bunquma ukuthi uzowudinga isikhathi esingakanani umuthi. Udokotela wakho uzobeka isikhathi sokwelashwa esifanele. Qedela izifundo ozinqunyelwe ngisho noma uzizwa ungcono.

10. Ungamisa nini i-doxofylline?

Isiqondiso sikadokotela wakho sibalulekile ngaphambi kokumisa i-doxofylline. Isimo sakho singase sibe sibi kakhulu, noma izimpawu zingabuya uma uyeka ngokushesha ukuphuza umuthi. Kufanele uqhubeke nemithi njengoba uyalelwe udokotela wakho, ngisho noma uqala ukuzizwa ungcono.

11. Ingabe kuphephile ukuphuza i-doxofylline nsuku zonke?

Yebo, kuphephile ukuthatha i-doxofylline nsuku zonke. Ucwaningo lwezokwelapha lubonise imiphumela emihle ezigulini ezithole ukwelashwa kuze kube yiminyaka emi-2. Ukusetshenziswa kwansuku zonke kuthuthukisa ukusebenza kwamaphaphu ngobuningi futhi kunciphise izenzakalo zesifuba somoya.

12. Yini okufanele uyigweme lapho uthatha i-doxofylline?

Hlala kude ne-:

  • Ukudla okune-caffeine neziphuzo
  • Ukuphuza utshwala
  • Imithi ethile, kuhlanganise ne-erythromycin, i-allopurinol kanye ne-cimetidine

13. Siyini isixwayiso se-doxofylline?

I-Doxofylline ayifanele ukuhlaselwa yisifuba somoya kungazelelwe ngenxa yezingozi ezingaba khona. Kufanele uqaphele uma unokuphazamiseka kwesigqi senhliziyo, izinkinga zesibindi, isifo sezinso, noma izilonda ze-peptic.

14. Ngingakwazi yini ukuthatha i-doxofylline kabili ngosuku?

Odokotela ngokuvamile banikeza i-400mg kabili ngosuku. Iziguli esezikhulile zenza kangcono ngomthamo oncishisiwe we-200mg kabili ngosuku.

15. Ingabe i-Doxofylline isetshenziselwa ukhwehlela?

I-Doxofylline ayinqunyelwe ngokuqondile ukukhwehlela. Kuyasiza ukucindezela ukukhwehlela ngokuvula imigudu yokuphefumula nokwenza ukuphefumula kube lula. Lokhu kunciphisa ngokungaqondile izimpawu zokukhwehlela.

16. Ingabe i-Doxofylline iphephile phakathi nokukhulelwa?

Idatha yokuphepha isalokhu inomkhawulo okwamanje. Odokotela banquma i-doxofylline ngesikhathi sokukhulelwa kuphela lapho izinzuzo zingaphezu kwezingozi ezingaba khona. Kufanele njalo ubuze udokotela wakho ngaphambi kokuyithatha ngenkathi ukhulelwe.

17. Ngingakwazi ukuthatha i-Doxofylline ne-montelukast ndawonye?

Le nhlanganisela inikeza izinzuzo ezimbili. Ucwaningo lukhombisa ukuthi i-doxofylline ene-montelukast inikeza i-bronchodilation eyengeziwe kanye nemiphumela elwa nokuvuvukala ngaphandle kokusabela okubi. Iziguli zilawula isifuba somoya, i-COPD, nezimo zokungezwani komzimba kangcono ngale nhlanganisela kune-montelukast iyodwa.