I-Etizolam

I-Etizolam

I-Etizolam ingeyesigaba se-thienodiazepine, okwenza ifane nokho kodwa ngokwekhemikhali yehluke kuma-benzodiazepines endabuko. Umuthi uqondise ama-GABA-A receptors ebuchosheni futhi udala imiphumela ye-anxiolytic, sedative kanye ne-muscle-relaxant. Ucwaningo lubonisa ukuthi i-etizolam ingase ibe lula ekusebenzeni kwengqondo kunemithi efanayo ngenkathi isasiza ngayo ukukhathazeka. Le nzuzo ivela esenzweni sayo esiqondiswe kuma-receptors athile ahlanganiswe nezimpawu zokukhathazeka.

Ekuqaleni, odokotela neziguli babecabanga ukuthi i-etizolam inengozi encane yokuba umlutha kunezinye i-benzodiazepines. Kodwa imibono ishintshile njengoba ukusetshenziswa kwayo kuye kwakhula kakhulu ngokuhamba kwesikhathi. Lesi sihloko sichaza ukuthi iyini ngempela i-etizolam, ukuthi iwuthinta kanjani umzimba wakho, ukusetshenziswa kwayo kwezokwelapha, imiphumela engemihle, kanye nemininingwane yokuphepha ebalulekile okufanele uyazi ngaphambi kokuthi ucabange ngokuthatha lo muthi.

Iyini i-Etizolam?

I-Etizolam ingeyeqembu le-thienodiazepine futhi yabelana ngokufana ne-benzodiazepines kodwa ihlukile ekwakhekeni kwamangqamuzana. Umuthi usebenzisa iringi ye-thiophene esikhundleni seringi ye-benzene kodwa udala imiphumela yokupholisa efanayo. Lo muthi we-anxiolytic osebenza isikhathi esifushane ngokuvamile usebenza amahora angama-6-8. Abakhiqizi bakhiqiza amaphilisi ngamandla ahlukahlukene: 0.5mg, 1mg noma 2mg. 

Ukusetshenziswa kwethebhulethi ye-Etizolam

Okulandelayo kukhona ukusetshenziswa okujwayelekile kwe-etizolam:

• ukukhathazeka iziyaluyalu
• Iziqephu zokwethuka
• Inkinga yokulala
• Izinhlobo ezithile ze ukuhlukunyezwa

Ungayisebenzisa Kanjani Futhi Nini Amathebulethi e-Etizolam

Odokotela batusa ukulandela imiyalelo kadokotela ngokucophelela. 

• Ukuthatha imithi ngokudla namanzi kusiza ukunciphisa ukungakhululeki kwesisu. 
• Ukudosa okuvamile kusebenza kangcono kunokusebenzisa ngezikhathi ezithile. 
• Iziguli eziningi zidinga umthamo owodwa noma emibili ngosuku
• Abantu abanenkinga yokulala kufanele bayisebenzise kusihlwa.

Imiphumela Emibi Yezibhebhe ze-Etizolam

Okulandelayo eminye imiphumela emibi ejwayelekile ye-etizolam:

• Ukukhathala nokozela
• Izinkinga zokulinganisela 
• isiyezi
• Ubunzima bokukhumbula izinto
• Izinkinga zokukhuluma
• Ukuphathwa yikhanda 
• Isihlungu esiswini

Ukusabela okungathi sína kungabandakanya izinkinga zokuphefumula, ukozela okwedlulele noma ukushintsha kwemizwa okungalindelekile.

Ukuqapha

• Iziguli kufanele zigweme utshwala ngokuphelele. Ukuxuba utshwala ne-etizolam kungaholela ezinkingeni zokuphefumula eziyingozi.
• Ukusebenzisa isikhathi eside kungase kubangele ukulutheka. 
• Ukumisa imithi kungazelelwe ngemva kokusetshenziswa isikhathi eside kungase kubangele izimpawu zokuhoxa. 
• Ukugadwa kwezokwelapha kuba semqoka phakathi nenqubo yokuyekiswa.

Indlela Amathebulethi E-Etizolam Asebenza Ngayo

I-Etizolam inyusa umsebenzi we-gamma-aminobutyric acid, esiza ubuchopho ukuba bukhululeke. Le thienodiazepine ibophezela endaweni ye-benzodiazepine kuma-receptors e-GABA-A futhi ithuthukise amasignali okuvimbela ohlelweni lwezinzwa olumaphakathi. Ucwaningo lubonisa ukuthi i-etizolam isebenza izikhathi ezi-6-10 kangcono kune-diazepam. Ama-subtypes ama-receptor ahlukene alawula imiphumela ethile. I-Alpha-1 receptors idala i-sedation, kuyilapho i-alpha-2 ne-alpha-3 subtypes isiza ukunciphisa ukukhathazeka.

Ngingakwazi yini ukuthatha i-Etizolam Neminye Imithi?

Imithi eminingi ingasebenzisana ne-etizolam futhi ishintshe indlela esebenza kahle ngayo:

• Utshwala
• Ama-Antifungal anjalo itraconazole 
• Ama-Antipsychotics
• Imishanguzo yegazi 
• I-Carbamazepine 
• I-fluvoxamine 
• Ama-painkillers we-opioid

Ulwazi Lomthamo

Umthamo olungile uncike kulokho owelaphayo:

• Ukukhathazeka / ukucindezeleka: Ngokuvamile i-1 mg izikhathi ezintathu ngosuku
• Ukuphazamiseka kokulala: 1-3mg kanye ngosuku ngaphambi kokulala
• Izimo ze-Psychosomatic: 0.5mg kathathu ngosuku

Abantu abadala asebekhulile akufanele bathathe ngaphezu kwe-1.5mg ngosuku. Isilinganiso esinqunyelwe udokotela wakho kufanele ngaso sonke isikhathi silandelwe ngokuqondile.

Isiphetho

I-Etizolam iboniswa ukuze ithole impumuzo ekukhathazekeni nasekuphazamisekeni kokulala ngesikhathi isetshenziswa kahle ngaphansi kokuqondisa kwezokwelapha. Njengama-benzodiazepines, le mithi ihlukile ngenxa yesakhiwo sayo sendandatho ye-thiophene futhi ingase ibe nemiphumela embalwa ekuqondeni. Kodwa lezi zinzuzo azenzi izingozi ezinkulu zihambe.

Kunamaphuzu amaningana iziguli okudingeka zicabange ngawo ngaphambi kokuthatha lo muthi. Kudingeka futhi ukudoswa ngokucophelela okuncike ezimeni ezithile, futhi iziguli esezikhulile zidinga amanani aphansi.

Imiphumela engemihle ingasukela ekozeleni okuncane kuye ezinkingeni zokuphefumula ezinzima, ikakhulukazi uma unotshwala noma eminye imithi ohlelweni lwakho. Ingozi yokuncika nayo ingenye yezinto ezikhathazayo kakhulu ngokusetshenziswa isikhathi eside.

Izinzuzo nezinkinga ze-Etizolam ziyenza isebenze njengenkemba esika nhlangothi zombili. Umuthi usiza iziguli eziningi ukulawula ukukhathazeka kwazo okuthena amandla. Kodwa ukukhathazeka okwandayo ngokulutheka kubonisa ukuthi kungani wonke umuntu kudingeka aqaphe. Iziguli kufanele zilandele imiyalelo kadokotela wazo ngqo, zigweme ukushintsha imithamo zizodwa, futhi zitshele udokotela wazo nganoma yikuphi ukusabela okungavamile ngokushesha.

Ukugadwa udokotela kuba okubalulekile lapho eyeka ukwelashwa ngoba izimpawu zokuhoxa zingaba zimbi kakhulu. Iziguli kanye nodokotela bazo kufanele bahlole ngokucophelela lezi zici ukuze babone ukuthi i-etizolam iyisinqumo esifanele esimweni sazo esithile.

Imibuzo Evame Ukubuzwa 

1. Ingabe i-etizolam iyisidakamizwa esiyingozi kakhulu?

Yebo, i-etizolam iza nezingozi ezingaba khona. Kungakwenza uncike njengama-benzodiazepines avamile. Umzimba wakho ungase uncike ngokomzimba ngemva kwamaviki angu-2-4 nje wokusetshenziswa okuvamile. Umuthi uba yingozi uma usetshenziswa kabi, ikakhulukazi uma uwuthatha nezinye izinto.

2. Yikuphi ukusetshenziswa okuyinhloko kwethebhulethi ye-etizolam?

Odokotela banquma i-etizolam ikakhulukazi ukwelapha ukuphazamiseka kokukhathazeka. Ungase uyitholele:

• Ukuhlaselwa ukwethuka
• Insomnia
• Izimo ezithile zokuquleka
• Ukuqina kwemisipha ngenxa yokukhathazeka

3. Yisiphi isikhathi esingcono kakhulu sokuphuza i-etizolam ekuseni noma kusihlwa?

Iziguli eziningi zenza kangcono ukuyithatha kusihlwa. Lokhu kukusiza ukuthi uzuze emiphumeleni yako ebangela ukulala futhi ugweme ukuzwa ukozela phakathi nosuku. Uma uwuthatha ukuze usize ngokulala, sebenzisa imizuzu engu-30-60 ngaphambi kokulala.

4. Amaphilisi e-etizolam athatha isikhathi esingakanani ukusebenza?

I-Etizolam isebenza ngokushesha kusistimu yakho. Cishe uzozwa imiphumela yasekuqaleni phakathi nemizuzu eyi-15-30 ngemuva kokuyithatha. Umuthi ufinyelela amazinga awo aphezulu egazini lakho phakathi nemizuzu engama-30 kuya emahoreni ama-2. Kungase kuthathe izinsuku ezimbalwa zokusetshenziswa okuvamile ukuze uthole inzuzo ephelele yokulwa nokukhathazeka.

5. Kwenzekani uma ngiphuthelwa umthamo?

Thatha umthamo ogejiwe uma ukhumbula phakathi namahora ambalwa. Yeqe futhi unamathele esimisweni sakho esijwayelekile uma isikhathi esiningi sesidlulile. Ungalokothi uthathe imithamo emibili ukuze ubuyisele eyodwa ogejile.

6. Kwenzekani uma ngiphuza ngokweqile?

Udinga usizo lwezokwelapha oluphuthumayo ngokushesha ukuze uthole ukweqisa kwe-etizolam. Buka izimpawu ezifana nokulala okwedlulele, ukudideka, inkulumo engahlangani kahle, ukungasebenzisani kahle, ukucabanga okunensayo, nezinkinga zokuphefumula ezingasongela ukuphila kwakho.

7. Ubani ongakwazi ukuthatha i-etizolam?

Akufanele uthathe i-etizolam uma une:

• Izimo ezinzima zokuphefumula
• I-apnea yokulala
• I-Myasthenia gravis
• Isifo sesibindi
• Umlando wokusetshenziswa kabi kwezidakamizwa
• Ukukhulelwa noma ukuncelisa

8. Zingaki izinsuku zokuphuza ithebhulethi ye-etizolam?

Ukwelashwa kwakho kufanele kube kufushane ngangokunokwenzeka. Isikhathi esinconyiwe singamaviki angama-2-4 kuhlanganisa nesikhathi sokuncipha. Lokhu kuyinkinga enkulu njengoba kusho ukuthi ukusebenzisa isikhathi eside kuphakamisa ingcuphe yokuba uncike.

9. Ungamisa nini i-etizolam?

Akufanele uyeke ukuthatha i-etizolam uwedwa. Khuluma nodokotela wakho kuqala ngoba ukuyeka kungazelelwe kudala izimpawu zokuhoxa njengokukhathazeka, ukudideka, ukuqwasha, ukuthuthumela, nokushaya kwenhliziyo. Odokotela bavamise ukusikisela ukwehliswa komthamo kancane kancane ukuze kuncishiswe le miphumela. Ucwaningo lukhombisa ukuthi ukuncika kungakhula phakathi nenyanga eyodwa nje.

10. Ingabe kuphephile ukuphuza i-etizolam nsuku zonke?

Ukusetshenziswa kwansuku zonke akunconyelwe ngenxa yezizathu ezimbili ezibalulekile. Ama-neurons akho ajwayela i-etizolam ngokukhiqiza ama-GABA-A receptors ambalwa. Lokhu kujwayela kudala ukubekezelelana, ukuncika, kanye nokulutheka okungenzeka. Ingozi yokuthola ukuncika iphezulu, futhi uzobhekana nezimpawu zokuhoxa lapho uyeka.

11. Yini okufanele uyigweme lapho uthatha i-etizolam?

Hlala kude ne-:

• Utshwala
• Imithi ye-opioid
• Imishini yokusebenza noma ukushayela 

12. Siyini isixwayiso se-etizolam?

Inkinga enkulu ingozi yokuncika. Ososayensi baqale bacabanga ukuthi i-etizolam inamandla aphansi okuncika. Manje ubufakazi bubonisa ukuthi ukuyeka ngokushesha kuholela ezimpawu zokuhoxa njengama-benzodiazepines. Iziguli ezinezinkinga zamaphaphu, izinkinga zesibindi, noma umlando wokulutheka zidinga ukunakekelwa okwengeziwe.

13. Ingabe i-etizolam iphephile ekunceliseni?

Abacwaningi abanakho ukuqonda okucacile. I-Etizolam idlula obisini lwebele ngamanani amancane. Odokotela bakhetha imithi ehlukene, ikakhulukazi ezinsaneni noma ezisanda kuzalwa.