I-Etodolac

I-Etodolac

Amaphilisi e-Etodolac asebenza njengenketho yokwelapha ebalulekile kubantu abalwayo osteoarthritis futhi rheumatoid arthritis's ubuhlungu, ububele, ukuvuvukala, nokuqina. Okuhle nge-etodolac ukukhetha kwayo okuphawulekayo-iqondise ukuvuvukala ngokuphumelelayo kunezidakamizwa eziqhathaniswayo. Iziguli eziningi zithola ukukhululeka kokuqala phakathi nesonto, nakuba izinzuzo ezigcwele zomuthi ngokuvamile zivela ngemva kwamasonto amabili. Naphezu kokuphumelela kwe-etodolac ekunikezeni usizo, iziguli kufanele zihlale zazi ngemiphumela engemihle engaba khona. Lesi sihloko sichaza konke mayelana namaphilisi e-etodolac, okuhlanganisa ukusetshenziswa kwawo, umthamo, nemiphumela emibi.

Iyini i-Etodolac?

I-Etodolac iyilungu lomndeni we-nonsteroidal anti-inflammatory (NSAID). Umuthi uvimba izinto ezisemzimbeni ezibangela ukuvuvukala, ubuhlungu kanye nomkhuhlane. Lesi sidakamizwa siphuma kwamanye ama-NSAID ngoba sibonisa izikhathi ezingu-5-50 ngaphezulu kokukhetha kwe-COX-2 kunama-enzyme e-COX-1.

Ukusetshenziswa kwe-Etodolac Tablet

Odokotela banikeza amaphilisi e-etodolac ku:

• Yelapha ubuhlungu obuncane kuya kobumaphakathi
• Lawula izimpawu ze-osteoarthritis kanye ne-rheumatoid arthritis
• Yehlisa ukuvuvukala, ukuvuvukala, ukuqina, nokungakhululeki kwamalunga
• Yehlisa izimpawu ze-juvenile arthritis ezinganeni (ukwakhiwa kokukhululwa okunwetshiwe)

Ungazisebenzisa Kanjani Futhi Nini Izibhebhe ze-Etodolac

Iziyalezo zikadokotela wakho kufanele zikuqondise ukuthi uyithatha kanjani i-etodolac. 

• Abantu abadala ngokuvamile badinga 200-400 mg njalo emahoreni angu-6-8 ukuze baqede ubuhlungu. Umthamo ojwayelekile usukela ku-300 mg izikhathi ezi-2-3 nsuku zonke kuye ku-400-500 mg kabili ngosuku ukuze uthole ukwelashwa kwe-arthritis. 
• Amaphilisi akhululiwe kufanele agwinywe aphelele - ungalokothi uwachoboze noma uwahlafune.
• Thatha umuthi wakho nokudla ukuze uvimbele izinkinga zesisu.
• Thatha i-etodolac ngesikhathi esifanayo usuku nosuku ukuze ugcine amazinga omthamo azinzile ukuze uthole imiphumela engcono kakhulu.

Imiphumela Emibi Yezibhebhe Etodolac

Imiphumela emibi evamile ye-etodolac yilezi:

• Isisu sithukuthele
• ukuqunjelwa noma isifo sohudo
• Gas
• isilungulela
• I-nausea
• Ukuvota
• isiyezi

Ukusabela okujulile kungabandakanya:

• Ukopha kwesisu
• Izilonda zesisu
• Izinkinga zesibindi
• Izinkinga zezinso
• Ukusabela kwesikhumba
• Izinkinga zenhliziyo nemithambo yegazi

Ukuqapha

• Tshela udokotela wakho ngazo zonke izithasiselo nemithi oyiphuzayo, kuhlanganisa namavithamini.
• Ukuhlaselwa yinhliziyo futhi imivimbo yizingozi ezingaba khona ngokusetshenziswa kwe-etodolac, ngisho nangesikhathi sokwelashwa kusenesikhathi. 
• Iziguli ezinesifuba somoya noma i-aspirin kufanele ziqhelelane nalo muthi. 
• Umuthi ungakhuphuka ukushaya kwegazi, kubangele ukugcinwa koketshezi, noma kubangele ukusabela okukhulu kwesikhumba.
• Ingozi yemiphumela emibi iphezulu kubantu abadala asebekhulile kanye nabantu abanezilonda zangaphambilini, ngakho khuluma nodokotela wakho ngaphambi kokuthatha lo muthi.
• Gwema utshwala ngenkathi uthatha i-etodolac, ngoba yandisa ingozi yezilonda zesisu nokopha.

Isebenza kanjani ithebhulethi ye-Etodolac

Ukusebenza kwe-Etodolac kuqala ezingeni lamaselula. Umuthi uvimba izinto ezibizwa nge-cyclooxygenase (COX) ama-enzyme abangela ukuvuvukala, ubuhlungu kanye nomkhuhlane. I-Etodolac igqamile ngoba ikhetha i-COX-2 ngaphezu kwe-COX-1 ama-enzyme izikhathi ezingu-5-50 ngokuphumelelayo. Lokhu kukhomba okukhethiwe kwe-COX-2 kunciphisa ukukhiqizwa kwe-prostaglandin ezindaweni zokulimala futhi kuvikela imisebenzi yesisu. Iziguli zithola ukuncipha okuphawulekayo kobuhlungu nokuvuvukala.

Ngingakwazi ukuthatha i-Etodolac neminye imithi?

I-Etodolac isebenzisana nezidakamizwa eziningi, okuhlanganisa kodwa kungagcini kulokhu okulandelayo:

• I-ACE inhibitors njenge-benazepril noma i-captopril
• Apixaban
• I-Cyclosporine
• I-Cyclothiazide
• Desmopressin
• Digoxin
• I-Heparin
• I-Methotrexate (imithi yomdlavuza/i-arthritis)
• Amanye ama-NSAID
• I-Pentoxifylline
• I-Prednisolone
• I-Salicylic Acid
• Warfarin

Izincomo eziqondile zikadokotela wakho ziyadingeka ukuze uthathe i-aspirin nge-etodolac. 

Ulwazi lomthamo

• Abantu abadala badinga i-200-400 mg njalo emahoreni angu-6-8 ukuze baqede ubuhlungu, ngomkhawulo wansuku zonke we-1000 mg. 
• Ukwelashwa kwe-arthritis kudinga ama-300 mg izikhathi ezi-2-3 ngosuku noma ama-400-500 mg kabili ngosuku. 
• Umthamo wengane uncike esisindweni sayo. Izingane ezineminyaka engu-6-16 ubudala zithola phakathi kuka-400-1000 mg kanye ngosuku ngokusekelwe isisindo sabo. 
• Iziguli eziningi zibona ukuthuthuka phakathi nesonto, nakuba izinzuzo ezigcwele ngokuvamile zivela ngemva kwamasonto amabili.

Isiphetho

I-Etodolac idlula eminye imithi yezinhlungu ngamandla ayo ayingqayizivele okukhomba ukuvuvukala izikhathi eziningi kunezidakamizwa ezifanayo. Le NSAID enamandla isiza izigidi zabantu abalwa nobuhlungu be-arthritis nokuvuvukala. Iziguli ngokuvamile ziqala ukuzizwa zingcono phakathi nesonto, futhi izinzuzo ezigcwele ziqala ngemva kwamasonto amabili okusetshenziswa njalo.

Umthamo ofanele wenza umehluko omkhulu endleleni ukwelashwa okusebenza kahle ngayo. Imithamo yabantu abadala isukela ku-200-1000 mg nsuku zonke ngokuya ngesimo sabo. Imithamo yezingane incike esisindweni sazo. Udokotela wakho udinga ukwazi ngayo yonke eminye imithi oyiphuzayo, njengoba i-etodolac ingasebenzisana nemithi eminingi eyahlukene.

I-Etodolac inganikeza ukukhululeka okukhulu kobuhlungu lapho iziguli ziyisebenzisa ngendlela efanele ngokugadwa kodokotela. Izinzuzo zokulwa nezinhlungu zomuthi kufanele zikalwe ngobungozi bawo. Qiniseka ukuthi ubambisana nethimba lakho lezempilo ukuze uthole ukuthi lo muthi uhambisana yini nezidingo zakho zokulawula izinhlungu.

Imibuzo Evame Ukubuzwa

1. Ingabe i-etodolac ingozi enkulu?

I-Etodolac iza nezingozi ezibalulekile okufanele uzazi. Amathuba akho okuhlaselwa yinhliziyo noma unhlangothi angase ande, ikakhulukazi uma usebenzisa isikhathi eside noma isifo senhliziyo esikhona. Umuthi ungabangela futhi ukopha okukhulu kwesisu noma emathunjini ngaphandle kwezimpawu eziyisixwayiso. Le ngozi iphezulu kubantu abadala kanye nabantu abanezilonda zangaphambili. Akufanele uwugweme umuthi ngenxa yalezi zingozi. Vele ube nengxoxo evulekile nodokotela wakho mayelana nezici zakho eziyingozi.

2. I-etodolac ithatha isikhathi esingakanani ukusebenza?

Ukukhululeka kobuhlungu kuqala cishe imizuzu engama-30 ngemva kokuthatha i-etodolac. Cishe uzokubona ukuthuthuka phakathi nesonto. Izinzuzo ezigcwele ngokuvamile zivela ngemva kwamaviki angu-1-2 okusetshenziswa okuvamile.

3. Kwenzekani uma ngiphuthelwa umthamo?

Thatha umthamo ogejiwe ngokushesha nje lapho ukhumbula. Noma kunjalo, yeqe uma cishe sekuyisikhathi somthamo wakho olandelayo ohleliwe futhi unamathele kushejuli yakho evamile. Ungathathi umuthi owengeziwe ukuze uvale umthamo ogejiwe.

4. Kwenzekani uma ngiphuza ngokweqile?

Ukweqisa kwe-etodolac kungakwenza uzizwe ukhathele futhi wozela, ube nesicanucanu, ukuhlanza, kanye ubuhlungu besisu. Ungase ubone indle enegazi noma emnyama ezimweni ezimbi kakhulu. Thola usizo lwezempilo oluphuthumayo ngokushesha ezimweni ezinjalo.

5. Ubani ongakwazi ukuthatha i-etodolac?

I-Etodolac ayilungele wonke umuntu. Kufanele uwugweme lo muthi uma:

• Ube nokungezwani komzimba ne-aspirin noma amanye ama-NSAID
• Muva nje wenze ukuhlinzwa kwe-heart bypass
• Yiba nokuhluleka kwenhliziyo okukhulu
• Uhlushwa isisu esisebenzayo noma ukopha/izilonda emathunjini
• Yiba nesifo sezinso esithuthukile

6. Kufanele ngiyiphuze nini i-etodolac?

Umzimba wakho udinga amazinga emithi angashintshi. Thatha i-etodolac ngesikhathi esifanayo nsuku zonke. Qiniseka ukuthi ulandela iziqondiso eziqondile zikadokotela wakho mayelana nesikhathi.

7. Zingaki izinsuku zokuphuza i-Etodolac?

Ubude bokwelashwa kwakho buncike esimweni sakho. Izimpawu ze-arthritis ziyathuthuka phakathi nezinsuku, kodwa i-etodolac ayikushintshi ukuqhubeka kwesifo isikhathi eside. Gcwalisa imithi oyinikeziwe ngaphandle uma udokotela wakho ekutshela okuhlukile.

8. Ungamisa nini i-Etodolac?

Kufanele uyeke ukuthatha i-etodolac izinsuku ezi-2 ngaphambi kokuhlinzwa ukuze uvimbele izinkinga zokuphuma kwegazi. Udokotela wakho angase akucele ukuthi uyeke uma uzwa ubuhlungu besisu, isilungulela, noma ukuhlanza okunegazi okubukeka njengezizathu zekhofi. Abesifazane abakhulelwe kudingeka bayeke cishe amasonto angu-20 ngaphandle uma udokotela wabo ebacebisa ngokuhlukile.

9. Ingabe kuphephile ukuthatha i-Etodolac nsuku zonke?

Iziguli ezine-rheumatoid arthritis noma osteoarthritis ingathatha i-etodolac isikhathi eside. Ukusetshenziswa isikhathi eside kuphakamisa ingozi yokopha esiswini, ukuhlaselwa yinhliziyo, nokushaywa unhlangothi. Ukuvakashela udokotela njalo kusiza ukulandelela noma yiziphi izinkinga ezingaba khona.

10. Yisiphi isikhathi esingcono kakhulu sokuthatha i-Etodolac?

Umzimba wakho ugcina amazinga emithi eqinile lapho uthatha i-etodolac ngesikhathi esifanayo usuku ngalunye. Ukuyithatha nokudla kusiza ukunciphisa izinkinga zesisu.

11. Yini okufanele uyigweme lapho uthatha i-Etodolac?

Ukuphuza utshwala kuphakamisa ingozi yokopha esiswini, ngakho kugweme. Nakhu okunye okumele ukuqaphele:

• Amanye ama-NSAID akufanele athathwe ndawonye
• Yeqa i-aspirin ngaphandle kokuthi uyalelwe
• Isikhumba sakho siyazwela elangeni, ngakho nciphisa ukuchayeka

12. Ungakwazi yini ukuthatha i-naproxen nge-etodolac?

Ukuthatha i-naproxen ne-etodolac ndawonye ngokuvamile akunconywa. Lokhu kuwukukhathazeka, njengoba kusho ukuthi ingozi yezinkinga zesisu, kuhlanganise nokubhoboza okungase kube yingozi, iyanda. Odokotela abavamile ukusikisela ukusebenzisa ama-NSAID amaningi ngesikhathi esisodwa.