I-Etoricoxib

I-Etoricoxib

I-Etoricoxib imithi elwa nokuvuvukala (i-NSAID) engeyona ingxenye yeqembu le-COX-2 inhibitor. Uma kuqhathaniswa namanye ama-NSAID avamile, i-Etoricoxib Tablet imithi ephumelela kakhulu. Yehlisa ukuvuvukala nobuhlungu ezifweni ezihlanganisa i-gout, i-ankylosing spondylitis, izinhlungu eziqhubekayo eqolo, i-osteoarthritis, kanye rheumatoid arthritis. Lo muthi uyalulekwa nakubantu abanobuhlungu obuncane ngemva kokuhlinzwa kwamazinyo. Umuthi usebenza ngokuvimbela ukukhiqizwa kwezithunywa zamakhemikhali ezithile ezibangela ukuvuvukala nokuba bomvu.

Ngaphezu kwalokho, ngokungafani namanye ama-NSAID, lo muthi awulimazi kakhulu isisu. Ngenxa yalokho, lo muthi uvame ukunikezwa.

Yiziphi ukusetshenziswa kwe-Etoricoxib?

I-Etoricoxib isidakamizwa esidambisa izinhlungu. Iqeda ubuhlungu, ukuqina, nokuvuvukala okulethwa ukugula okuningana, okuhlanganisa i-ankylosing spondylitis (ebangela ubuhlungu nokuqina emathanjeni omgogodla), i-osteoarthritis (ebangela amalunga abuhlungu ngoba uqwanga oluvikelayo phakathi kwamathambo amabili selugugile), rheumatoid arthritis (okubangela ukuvuvukala nobuhlungu emalungeni amancane omzimba wakho), njll. I-Etoricoxib akufanele isetshenziswe yinoma ubani ongaphansi kweminyaka engu-16 ubudala, ngokwezincomo. Ngaphezu kwalokho, yazisa udokotela wakho uma ukhulelwe, ucabangela ukukhulelwa, noma ukuncelisa ingane ngaphambi kokusebenzisa lesi sidakamizwa.

Ungayithatha kanjani futhi nini i-Etoricoxib?

Kukhona izinguqulo ezijovwayo nezethebulethi ze-Etoricoxib. Njengoba uqondiswa udokotela wakho, thatha i-Etoricoxib ngendlela yomlomo. I-Etoricoxib ingalawulwa ngomjovo ngudokotela. I-Etoricoxib kufanele isetshenziswe kanye ngosuku, njengoba nje kunqunywe udokotela wakho. Umthamo wemithi ofanele isimo sakho uzotuswa kuwe. Isibonelo, iziguli ze-Osteoarthritis zivame ukuthola incwadi kadokotela ye-30 mg kanye ngosuku. Kodwa-ke, umthamo unganwetshwa ube ngu-60 mg uma kunesidingo. Funda ipheshana lolwazi lomkhiqizi ophrintiwe ngaphakathi kwephakheji ngaphambi kokuthatha i-Etoricoxib. Izohlinzeka ngemininingwane eyengeziwe mayelana nemithi kanye nohlu olubanzi lwanoma yimiphi imiphumela engemihle ongahlangabezana nayo uma uyiphuza.

Ngemva kokuthatha isiphuzo samanzi, dla amaphilisi. Ungathatha umuthi ngokudla noma ngaphandle kokudla. Nokho, ukuwuthatha ngaphandle kokudla kungase kusize umuthi usebenze ngokushesha okukhulu. Zama ukuphuza amaphilisi akho kanyekanye usuku ngalunye ukuze wenze kube lula ukuwakhumbula.

Iyini imiphumela emibi ye-Etoricoxib?

Abantu ngabanye bangase babe nemiphumela engemihle elandelayo:

• Ubuhlungu besisu, ubuhlungu besisu, nokungagayeki.
• Ukuzizwa unesiyezi noma ukhathele.
• Uhudo noma ukuqunjelwa.
• Ukuvuvukala kwe-ankle, ukugcina uketshezi, ukushaya kwenhliziyo, ukuphelelwa umoya, imihuzuko, ubuhlungu bekhanda, kanye nezimpawu ezinjengomkhuhlane ezinye zezimpawu ezingase zenzeke.

Kufanele uyeke ngokushesha ukuthatha i-Etoricoxib futhi ufune ukwelashwa uma uhlangabezana nanoma yiziphi izimpawu ezingavamisile kodwa ezingaba yingozi ezibalwe ngezansi:

• Izinkinga zokuphefumula, njengokushaywa umoya noma ukuphelelwa umoya.
• Noma yiziphi izinkomba zokusabela kwe-allergies, njengokuvuvukala ezindebeni zakho noma ebusweni noma ukuqubuka okukhulu kwesikhumba.
• Uma uzwa izinhlungu zesisu ezibuhlungu, indle emnyama, igazi emhlanzweni wakho, noma wopha lapho uchama.

Yiziphi izinyathelo zokuphepha okufanele zithathwe?

• Uma unomlando wokopha esiswini noma isilonda, izinkinga zesibindi noma izinso, ukuphelelwa amanzi emzimbeni ngenxa yokuhlanza isikhathi eside noma isifo sohudo, noma ukuqunjelwa ngenxa yokugcinwa koketshezi, yazisa udokotela wakho ngaphambi kokusebenzisa i-Etoricoxib.
• Uma une-high blood pressure engelashiwe noma engalawulwa, yazisa udokotela wakho njengoba i-Etoricoxib ingase inyuse umfutho wegazi kwabanye abantu.
• Uma uthola ukwelashwa kokugula, gwema ukusebenzisa i-Etoricoxib ngoba ingenza umkhuhlane ube mkhulu.
• Uma ubhema, unesifo sikashukela, noma unesifo i-cholesterol ephezulu, akufanele usebenzise i-Etoricoxib ngoba ingase ikhulise ingozi yokuhlaselwa yinhliziyo noma unhlangothi.
• Ngemva kokuthatha i-Etoricoxib, gwema ukulala phansi okungenani imizuzu engu-30.
• I-Etoricoxib akufanele ithathwe yinoma ubani ohlaselwe yinhliziyo noma unhlangothi.
• Lo muthi awukaze unikezwe abesifazane abakhulelwe ngaphandle uma kunesidingo. Ngaphambi kokusebenzisa lo muthi, khuluma nodokotela wakho ngazo zonke izingozi nezinzuzo. Udokotela wakho angase asikisele inketho engeyona ingozi encane kuye ngempilo yakho yamanje.

Kuthiwani uma ngiphuthelwa umthamo noma ngine-overdose ye-Etoricoxib?

Ngokushesha nje lapho ukhumbula, thatha umthamo ogejiwe womuthi. Kufanele uyeke umthamo olandelayo ohleliwe uma umthamo ogejiwe uwela ngaleso sikhathi. Ungathathi umthamo ophindwe kabili ukuze uvale ongekho.

Ubuhlungu besisu, isicanucanu, izinkinga zokuphefumula, ngisho nesifo sokuquleka konke okungaba yizimpawu zokudlula umthamo. Uma ucabanga ukuthi uthathe kakhulu, thola ngokushesha usizo oluphuthumayo.

Yiziphi izimo zokugcina ze-Etoricoxib?

• Ukugcina noma yiziphi izidakamizwa zingabonwa futhi zifinyeleleke ezinganeni kubalulekile.

• Gcina kude nokushisa okuqondile nokukhanya endaweni epholile, eyomile.

• Ungayigcini imithi ephelelwe yisikhathi noma engadingeki futhi uyilahle ngendlela efanele.

Ukusebenzisana neminye imithi

Ukusebenzelana neminye imithi:

• I-Methotrexate, i-Ciclosporin, i-Tacrolimus
• isisu
• Ama-antibiotic afana ne-Rifampicin
• Amaphilisi okulawula ukuzalwa angama-hormone
• Izinto ezinciphisa igazi njenge-warfarin
• I-Lithium - umuthi osetshenziselwa ukwelapha i-mania
• Ukusebenzisa i-Etoricoxib kanye ne-Aspirin kwandisa amathuba okuba nezilonda zesisu.

I-Etoricoxib ibonisa ngokushesha kangakanani imiphumela?

Umthamo owodwa we-Etoricoxib uzoqala ukunciphisa ubuhlungu phakathi nehora, kodwa ukulinganisa okuphindaphindiwe emasontweni ambalwa kuzobangela ukuthi kuphumelele kakhulu ekunciphiseni ukuvuvukala.

Ukuqhathaniswa komuthi we-Etoricoxib neNaproxen

Imibuzo Evame Ukubuzwa

1. Isetshenziselwa ini i-Etoricoxib?

I-Etoricoxib iyisidakamizwa esilwa nokuvuvukala (i-NSAID) esingasebenzisi ukuvuvukala (i-NSAID) esetshenziselwa ukukhulula ubuhlungu nokuvuvukala okuhambisana nezimo ezifana ne-osteoarthritis, i-rheumatoid arthritis, i-ankylosing spondylitis, kanye ne-acute gouty arthritis.

2. Isebenza kanjani i-Etoricoxib?

I-Etoricoxib isebenza ngokuvimbela ukusebenza kwama-enzyme athile (COX-2) anesibopho sokukhiqiza i-prostaglandin, edlala indima ekuvuvukeni nasebuhlungu. Ngokunciphisa amazinga e-prostaglandin, i-Etoricoxib isiza ekudambiseni ubuhlungu nokuvuvukala.

3. Ingabe i-Etoricoxib ingasetshenziselwa ubuhlungu obukhulu?

I-Etoricoxib inqunywe ngokuyinhloko ezimweni ezingapheli ezihlobene nobuhlungu nokuvuvukala, njenge-osteoarthritis kanye nesifo samathambo. Ngokuvamile ayisetshenziselwa ukuphatha ubuhlungu obukhulu.

4. Yimiphi imiphumela emibi evamile ye-Etoricoxib?

Imiphumela engemihle evamile ingase ihlanganise ikhanda elibuhlungu, isiyezi, i-edema, nezinkinga zesisu ezifana nokungagayeki kokudla. Imiphumela emibi kakhulu ayivamile kodwa ingabandakanya ukopha emathunjini, izehlakalo zenhliziyo nemithambo yegazi, kanye nezinkinga zesibindi.

5. Ingabe i-Etoricoxib ingathathwa kanye nokudla?

I-Etoricoxib ingathathwa ngokudla noma ngaphandle kwayo. Kodwa-ke, ukuyithatha kanye nokudla kungasiza ukunciphisa ingozi yemiphumela emibi yesisu.

References:

https://patient.info/medicine/etoricoxib-for-pain-and-inflammation-arcoxia#nav-5 https://www.medicines.org.uk/emc/product/9317/pil#gref

Umshwana wokuzihlangula: Ulwazi olunikezwe lapha alwenzelwe ukufaka iseluleko esivela kuchwepheshe wezokunakekelwa kwempilo. Ulwazi aluhloselwe ukumboza konke ukusetshenziswa okungenzeka, imiphumela engemihle, izinyathelo zokuphepha, nokusebenzisana kwezidakamizwa. Lolu lwazi aluhloselwe ukuphakamisa ukuthi ukusebenzisa umuthi othile kufanelekile, kuphephile, noma kuyasebenza wena noma omunye umuntu. Ukungabi bikho kwanoma yiluphi ulwazi noma isexwayiso mayelana nomuthi akufanele kuhunyushwe njengesiqinisekiso esicacile esivela enhlanganweni. Sikweluleka ngokuqinile ukuthi uthintane nodokotela uma kukhona okukukhathazayo ngomuthi futhi ungalokothi usebenzise umuthi ngaphandle kwencwadi kadokotela.