I-Famotidine

I-Famotidine

I-Famotidine umuthi onamandla okungeyesigaba semithi eyaziwa ngokuthi ama-histamine-2 (H2) receptor antagonists. Lo muthi unethonya esiswini ngokunciphisa ukukhiqizwa kwe-asidi, okuwenza ube yithuluzi elibalulekile ekwelapheni izimo ezahlukahlukene zesisu, njenge. isifo se-peptic ulcer, I-GERD, kanye nesifo se-Zollinger-Ellison.

Ukusetshenziswa kweFamotidine

I-Famotidine, isivimbeli esinamandla se-H2, inokusetshenziswa okubanzi ekwelapheni izinkinga ezahlukahlukene zokugaya ukudla, njenge: 

• Izilonda esiswini nasemathunjini 
• Umuthi we-Famotidine usiza ekwelapheni izilonda ezikhona futhi uvimbela izilonda zamathumbu ukuthi zingaphindeleli ngemva kokuba ziphole.
• Ikhulula izimpawu zeGERD futhi ivikele umminzo ekulimaleni okwengeziwe.
• Izinkinga ezithile zesisu nomphimbo, njenge-erosive esophagitis kanye ne-Zollinger-Ellison syndrome

Ukusetshenziswa kwethebhulethi ye-Famotidine

Ukusetshenziswa ngendlela efanele komuthi we-famotidine kubalulekile ukuze kuzuzwe imiphumela engcono kakhulu futhi kuncishiswe imiphumela engemihle engaba khona. Ukuze usebenzise lo muthi ngempumelelo, iziguli kufanele zilandele ngokucophelela imiyalelo kadokotela wazo noma iziqondiso ezisephakejini.

• Thatha ithebhulethi eyodwa noma i-capsule ngengilazi yamanzi njengoba kudingeka. Kubalulekile ukugwinya amaphilisi namaphilisi wonke ngaphandle kokuwahlafuna. 
• Uma kusetshenziswa amaphilisi ahlafunwayo, wahlafune kahle bese uwagwinya. 
• Uma usebenzisa uhlobo loketshezi lomlomo lwe-famotidine, ukukala umthamo onembile kubalulekile. Sebenzisa inkomishi yomuthi noma ukhezo lokulinganisa olumakiwe.
• I-Famotidine ingathathwa ngokudla noma ngaphandle kwayo, inikeze ukuguquguquka esimisweni somuntu sansuku zonke.
• Thatha i-famotidine imizuzu engu-15-60 ngaphambi kokudla noma iziphuzo ezingase zidale indigestion. 

Imiphumela Emibi Yethebhulethi ye-Famotidine

Nakuba amaphilisi e-famotidine esiza abantu abaningi, angabangela imiphumela engafuneki kwezinye izimo, njengale:

Imiphumela emibi ejwayelekile:

• bekhanda
• ukuqunjelwa
• Uhudo

Ezimweni ezingavamile, umuthi we-famotidine ungabangela imiphumela emibi kakhulu edinga ukunakwa ngokushesha. Lokhu kubandakanya:

• Ukungezwani Nomzimba: Bheka izimpawu ezifana nokuqubuka, ukulunywa, isiyezi esinzima, ukuvuvukala (ikakhulukazi ubuso, ulimi, noma umphimbo), noma ukuphefumula kanzima.
• Ukopha okungajwayelekile noma imihuzuko noma ukukhomba amabala abomvu esikhumba
• Izinguquko Zempilo Yengqondo: Abanye abantu baba nokukhathazeka, ukucindezeleka, noma ngisho nokubona izinto ezingekho.
• Ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla
• Ukuquleka (okungavamile) 

Eminye imiphumela emibi engavamile engenzeka ihlanganisa:

• Ubunzima bokuhambisa amathumbu
• Izinguquko ekunambithekeni noma ekunambithekeni okubi
• Umlomo owomile noma isikhumba
• Ukuncipha kwentshisekelo emisebenzini yocansi
• Ubuhlungu bemisipha noma ukuqina

Kwezinye izimo, i-famotidine ingabangela imiphumela emibi kakhulu edinga ukunakwa ngokushesha. Lokhu kubandakanya:

• Izimpawu zokutheleleka (umphimbo obuhlungu oqhubekayo, umkhuhlane, noma amakhaza)
• Ukulimala kalula noma ukopha
• Isiyezi esinzima noma ukuquleka
• ukuquleka

Ukuqapha

Uma usebenzisa i-famotidine, kubalulekile ukuthatha izinyathelo ezithile zokuphepha ukuze uqinisekise ukwelashwa okuphephile nokusebenzayo, okuhlanganisa:

• Iziguli kufanele zazise udokotela wazo mayelana nokungezwani komzimba nezinto ezithile, ikakhulukazi i-famotidine nezinye izivimba-H2 njenge-cimetidine, i-ranitidine, noma ezinye izinto. 
• Izimo ezithile zezokwelapha, njengezinkinga zamasosha omzimba, izinkinga zezinso, izimo zesibindi, izinkinga zamaphaphu njengesifuba somoya noma i-COPD, ezinye izinkinga zesisu, noma umdlavuza.
• I-Famotidine akufanele isetshenziswe ezinganeni ezingaphansi kweminyaka engu-12 ngaphandle uma iqondiswa udokotela. 
• Abantu abadala abadala
• Abesifazane abakhulelwe kufanele basebenzise i-famotidine kuphela lapho kudingeka.
• Iziguli ezinezinkinga zezinso zingadinga ukulungiswa komthamo.

Ezinye izimpawu ezibonakala sengathi isilungulela kalula zingabonisa isimo esibi kakhulu, njenge:

• isilungulela okuhambisana nokuba nekhanda elilula, ukujuluka, noma isiyezi
• Isifuba, umhlathi, ingalo, noma ubuhlungu behlombe, ikakhulukazi ngokuphelelwa umoya noma ukujuluka okungajwayelekile
• Ukulahlekelwa kwesisindo esingachaziwe
• Ubunzima noma ubuhlungu lapho ugwinya ukudla
• Igazi emhlanzweni noma emhlanzweni livela njengezizathu zekhofi
• Indle enegazi noma emnyama
• Isilungulela esithatha isikhathi esingaphezu kwezinyanga ezintathu
• Isicanucanu, ukuhlanza, noma ubuhlungu besisu

Isebenza kanjani i-Famotidine

I-Famotidine, umuthi onamandla, ithinta indlela yokukhiqiza i-asidi esiswini. Lo muthi ungowesigaba semithi eyaziwa ngokuthi i-histamine-2 (H2) receptor antagonists, esebenza ngokubopha ngokuncintisana kuma-H2 receptors kumaseli e-parietal. Ngokwenza kanjalo, i-famotidine ivimbela ngempumelelo izenzo ze-histamine. Lokhu kuvinjelwa kunomthelela omkhulu kulokhu:

• Ukukhiqizwa Kwe-Acid Enciphile: I-Famotidine icindezela kokubili amazinga e-acidity kanye nevolumu yokuphuma kwesisu.
• Ukuvinjelwa kwe-Basal kanye Nocturnal Secretion: Umuthi unciphisa ukukhishwa kwe-asidi ngesikhathi sokuphumula nasebusuku.
• Imfihlo Eyehlisiwe Evuselelwe: I-Famotidine iphinde yehlise ukukhushulwa kwe-asidi okubangelwa izisusa ezihlukahlukene ezifana nokudla, i-caffeine, i-insulin, ne-pentagastrin.

Ngingakwazi Ukuthatha I-Famotidine Ngeminye Imithi?

Nakuba iphumelela ekwelapheni izinkinga ezihlukahlukene zokugaya ukudla, i-famotidine ingasebenzisana neminye imithi eminingi. Eminye yemithi engase ihlanganyele ne-famotidine ihlanganisa:

• I-Alprazolam 
• I-Amphetamine/dextroamphetamine
• Apixaban
• I-Aspirin (kokubili amandla aphansi navamile)
• I-Clopidogrel
• I-diphenhydramine
• I-Duloxetine
• I-Escitalopram
• Levothyroxine
• I-Loratadine

Indlela yokusebenza ye-Famotidine ingaba nomthelela endleleni umzimba oyibamba ngayo imikhiqizo ethile. Eminye yemithi engase ibe nomthelela ihlanganisa:

• I-Atazanavir
• Ama-antifungal athile e-azole (itraconazole ne-ketoconazole)
• I-Dasatinib
• Levoketoconazole
• I-Pazopanib
• I-Sparsentan

Ngaphandle kokusebenzelana kwezidakamizwa, i-famotidine iphinde ibe nokusebenzisana notshwala nokudla okuthile.

Ulwazi Lomthamo

Umthamo we-Famotidine uyahlukahluka kuye ngezimo kanye neminyaka yesiguli. Kubalulekile ukulandela imiyalelo kadokotela noma iziqondiso ezikulebula ngokucophelela.

Kubantu abadala kanye nezingane ezinesisindo esingamakhilogremu angu-40 noma ngaphezulu, imithamo evamile yezimo ezihlukahlukene yile:

1.Ukuvimbela Ukuphindaphinda Kwezilonda: 20 mg kanye ngosuku.

2. Ukwelapha i-Erosive Esophagitis (isilungulela):

• 20 mg kanye noma kabili ngosuku, ekuseni nakusihlwa
• Ngaphandle kwalokho, 40 mg kanye ngosuku ngaphambi kokulala
• Ubude besikhathi: Kufika emavikini angu-12

3. Ukulawula Isifo Sokuqunjelwa Kwe-Gastroesophageal Reflux (GERD):

• 20 milligram kabili ngosuku, ekuseni nangaphambi kokulala
• Ubude besikhathi: Kufika emavikini angu-6

4. Ukwelapha Izilonda Zesisu:

• 20 mg izikhathi ezimbili ngosuku, ekuseni nakusihlwa
• Ngaphandle kwalokho, 40 mg kanye ngosuku ngaphambi kokulala
• Ubude besikhathi: Kufika emavikini angu-8

5.Ukwelapha i-Zollinger-Ellison Syndrome (i-asidi yesisu eyeqile):

• Umthamo wokuqala: 20 mg njalo emahoreni ayi-6
• Udokotela angase alungise umthamo njengoba kudingeka

Udokotela kufanele anqume ukusetshenziswa kanye nomthamo wezingane ezinesisindo esingaphansi kwama-40 kg.

Le mihlahlandlela yomthamo ijwayelekile, futhi izinhlelo zokwelashwa ngazinye zingahluka. Hlala uthintana nodokotela ukuze uthole ulwazi lomuntu siqu lokudosa.

Isiphetho

I-Famotidine isiza ukuphatha izindaba ezahlukahlukene zokugaya ngokunciphisa ukukhiqizwa kwe-asidi yesisu. Lo muthi unikeza impumuzo ezimeni ezisukela kusilungulela kuya ezinkingeni ezinzima njengezilonda kanye neGERD. Ukusebenza kwayo, okuhambisana nokutholakala kwayo kuzo zombili izinhlobo zemithi kanye ne-counter-the-counter, kuyenza ibe ithuluzi elibalulekile kubantu abaningi abanenkinga yokungakhululeki okuhlobene ne-asidi.

Nakuba i-famotidine ngokuvamile iphephile futhi isebenza ngempumelelo, kuphoqelekile ukuyisebenzisa ngendlela efanele futhi uqaphele imiphumela engemihle engaba khona kanye nokusebenzisana. Iziguli kufanele ngaso sonke isikhathi zilandele ngokucophelela imiyalelo kadokotela noma iziqondiso ezikulebula.

FAQ sika

1. Isetshenziselwa ini i-famotidine?

Ukusebenza kwe-famotidine ekulawuleni izimo ezihlobene ne-asidi kutholakala emandleni ayo okubhekana nembangela yokukhiqizwa kwe-asidi ngokweqile. Lo muthi usiza ukukhulula izimpawu ze-acid reflux kanye nesilungulela. Iphatha izimo ezahlukahlukene, kufaka phakathi:

• Isifo se-reflux ye-gastroesophageal (GERD)
• Izilonda zesisu namathumbu
• I-Erosive esophagitis
• I-Zollinger-Ellison syndrome

2. Ingabe i-famotidine iphephile ezinso?

I-Famotidine ngokuvamile ibhekwa njengephephile ezinso. Nokho, abantu abanesifo sezinso noma abakhubazekile bangadinga izinyathelo zokuphepha ezikhethekile. Umzimba ungase ungayisusi i-famotidine ngempumelelo, okungase kuholele emazingeni aphakeme ezidakamizwa kanye nemiphumela engemihle eyengeziwe. Abantu abanezinkinga zezinso kufanele babonane nodokotela wabo ngaphambi kokuthatha i-famotidine ukuze baqinisekise ukulinganisa nokuqapha okufanele.

3. Ubani okufanele agweme i-famotidine?

Nakuba i-famotidine ngokuvamile ibekezelelwa kahle, abantu abathile kufanele bayigweme noma bayisebenzise ngokuqapha:

• Abantu abanesifo sezinso esimaphakathi noma esinzima
• Abantu abanesifo sesibindi
• Abantu abanomlando we izinkinga zenhliziyo
• Abantu abanamasosha omzimba asengozini
• Abantu abanezinkinga zamaphaphu, njengesifuba somoya noma isifo esingamahlalakhona sokuvimbela amaphaphu (COPD)
• Abantu abanezinye izinkinga zesisu, njengezimila zesisu noma ezinye izinkinga zesisu
• Abesifazane abancelisayo
• Abantu abadala abadala

4. Ingabe i-famotidine iphephile enhliziyweni?

I-Famotidine ngokuvamile ibhekwa njengephephile enhliziyweni. Nokho, ingase ihlangane nemithi ethile ethinta inhliziyo, njengemithi elwa nokuvuvukala. Ngakho-ke, kuhle ngaso sonke isikhathi ukubonana nodokotela, ikakhulukazi kulabo abanezimo zenhliziyo ezivele zikhona noma labo abathatha eminye imithi ehlobene nenhliziyo.

5. Kungani uthatha i-famotidine ebusuku?

Isikhathi esingcono kakhulu sokuthatha i-famotidine singahluka kuye ngezidingo zomuntu ngamunye kanye nesimo sokwelashwa. Ukuthatha i-famotidine ebusuku kunezinzuzo ezimbalwa:

• Ukusebenza kahle: I-Famotidine iphumelela kakhulu ekwehliseni ukukhiqizwa kwe-asidi esiswini lapho isisu singenalutho, ngokuvamile okwenzeka ebusuku.
• Ukunciphisa Izimpawu: Ukuthatha i-famotidine ngaphambi kokulala kungasiza ukuvimbela noma ukunciphisa izimpawu ze-acid reflux noma ezinye izimo ezimbi kakhulu ebusuku.
• Umphumela Omkhulu: Umphumela omkhulu uvame ukwenzeka phakathi kwamahora angu-1 kuya kwangu-3 futhi uthatha amahora angu-10 kuya kwangu-12 ngemva komthamo owodwa.
• Ukulala Okuthuthukisiwe: Ngokunciphisa izimpawu ze-acid reflux yasebusuku, i-famotidine ingasiza ukuthuthukisa ikhwalithi yokulala.

6. Ngingakwazi yini ukuthatha i-famotidine ngemva kokudla?

Ungathatha i-famotidine ngokudla noma ngaphandle kokudla. Kodwa-ke, ukuthatha i-famotidine ngokudla kungase kubambezele kancane ukumuncwa kwemithi, kuthinte ukusebenza kwayo. Odokotela ngokuvamile batusa ukuyithatha imizuzu engu-30 kuya kwengu-60 ngaphambi kokudla kube nenzuzo ukuze uthole imiphumela emihle, ikakhulukazi ukuvimbela isilungulela noma ukugayeka kokudla esiswini.