I-Fluoxetine

I-Fluoxetine

I-Fluoxetine, i-antidepressant enikezwa kabanzi, ibisiza izigidi zabantu emhlabeni wonke ukuphatha i-antidepressant yabo Impilo yengqondo. Lesi sidakamizwa esimangalisayo, i-fluoxetine, singokwesigaba se-serotonin reuptake inhibitors (SSRIs) esikhethiwe futhi sesiyindlela yokwelapha ehlukahlukene yokuphazamiseka kwemizwa.

Le bhulogi ihlose ukukukhanyisela ngokusetshenziswa kwe-fluoxetine, imiphumela engemihle engaba khona, nokusetshenziswa okufanele ukuze ikusize wenze izinqumo ezingcono mayelana nokwelashwa kwakho kwengqondo.

Iyini i-Fluoxetine?

I-FDA igunyaze lo muthi onamandla wokwelapha izimo ezehlukene zengqondo. Ingokwesigaba sezidakamizwa ezibizwa ngokuthi i-selective serotonin reuptake inhibitors (SSRIs). Lesi sidakamizwa esinamandla sithonya amakhemikhali obuchopho, sisize ukugcina ukulinganisela kwengqondo.

I-Fluoxetine ibonise ukusebenza kahle ekwelapheni izimo ezingokwengqondo eziningi. Lokhu kuhlanganisa i-depressive disorder enkulu, ukuphazamiseka okukhulu-okucindezelayo (OCD), ukuphazamiseka kokwethuka, i-bulimia, ukuphazamiseka kokudla kakhulu, kanye ne-premenstrual dysphoric disorder. Ibuye isetshenziselwe ukwelapha ukudangala okuguquguqukayo, okuhlanganisa izimo zokucindezeleka okungazweli ekwelapheni lapho kuhlanganiswa ne-olanzapine.

Ukusetshenziswa kwethebhulethi ye-Fluoxetine

I-Fluoxetine, umuthi oguquguqukayo, unokusetshenziswa okubanzi ekwelapheni izimo ezahlukahlukene zempilo yengqondo, njenge:

• Umsebenzi wawo oyinhloko ukwelapha ukudangala, ukunikeza impumuzo kubantu abazabalaza nemizwa eqhubekayo yokudabuka nokuphelelwa ithemba.
• Enye yezinto ezisetshenziswa kakhulu i-fluoxetine isekwelapheni i-obsessive-compulsive disorder (OCD). 
• I-fluoxetine yezidakamizwa nayo inomthelela ekwelapheni ukuphazamiseka kokwethuka. Labo abahlushwa ukuhlaselwa okungazelelwe, okungalindelekile kokwesaba okukhulu nokukhathazeka ngalokhu kuhlaselwa bangathola ukukhululeka ngokusebenzisa i-fluoxetine. 
• Okunye ukusetshenziswa okuphawulekayo kwe-fluoxetine ekwelapheni ukuphazamiseka kwemikhuba yokudla, ikakhulukazi i-bulimia. Umuthi usiza ekunciphiseni iziqephu zokuzitika ngokweqile kanye nokuziphatha kokuhlanza okuhambisana nalesi simo. 
• I-Fluoxetine inendima ebalulekile ekudambiseni izimpawu ze-premenstrual dysphoric disorder (PMDD). Abesifazane abanenkinga yokushintshashintsha kwemizwelo, ukucasuka, ukuqunjelwa, nokuthamba kwebele okuhlobene nomjikelezo wabo wokuya esikhathini bangathola impumuzo ngokusebenzisa i-fluoxetine. 

Ngaphezu kwalokhu kusetshenziswa okuyinhloko, odokotela bangase banikeze i-fluoxetine yezidakamizwa kwezinye izimo. Lokhu kungafaka:

• Ukuphazamiseka kokunaka-ukushoda
• Ukuphazamiseka kobuntu bomngcele
• Ukuphazamiseka kokulala
• Ubuhlungu bekhanda obungapheli
• I-post-traumatic stress disorder
• I-Tourette's syndrome
• Ukukhuluphala
• Izinkinga zocansi
• zokwesaba

Ungayisebenzisa kanjani iFluoxetine Tablet

• Iziguli kufanele ziwuphuze lo muthi njengoba nje udokotela eqondisa ukuze zithole okuningi ekwelashweni kwazo. 
• Abantu ngabanye bangathatha i-fluoxetine ngokudla noma ngaphandle kokudla, okuyenza ibe inketho evumelana nezimo zendlela yokuphila ehlukahlukene. Nokho, kungcono ukunamathela ngesikhathi esifanayo usuku ngalunye ukuze ulondoloze ukungaguquguquki. 
• Kulabo ababhekana nokuphazamiseka kokulala, ukuphuza imithi ekuseni kungase kube yinzuzo.
• Kulabo abasebenzisa ifomu le-oral liquid, nyakazisa ibhodlela kahle ngaphambi kokukala umthamo ngamunye. Kunconywa ukusebenzisa inkomishi yomuthi ephawuliwe noma isipuni sokulinganisa ukuze uthole umthamo onembile. 
• Iziguli kufanele zithathe umthamo ngokushesha nje lapho zikhumbula uma umthamo weqiwe. Kodwa-ke, uma sekusondele isikhathi sethamo elilandelayo, kufanele beqe umthamo futhi baqhubeke neshejuli yabo evamile. 

 Imiphumela Emibi Yethebhulethi ye-Fluoxetine

Imiphumela emibi evamile yesidakamizwa i-fluoxetine ihlanganisa:

• I-nausea
• Ukuphathwa yikhanda
• Ubunzima bokulala
• Uhudo
• Ukukhathala noma ubuthakathaka bemisipha

Imiphumela engemihle engajwayelekile kodwa eyingozi kakhulu yilena:

• Ukuzuza noma ukuncipha kwesisindo okungachazeki
• Ushintsho ezikhathini zokuya esikhathini
• Imizwa yenjabulo eyedlulele noma yokungahlaliseki
• Ukusuka okungavamile noma ukulimaza
• Ubuhlungu besifuba noma ukuphelelwa umoya
• Isiyezi esinzima noma ukuquleka
• Ukuqhanyelwa okubuhlungu isikhathi eside
• Ukuqunjelwa noma ukulingana
• Izimpawu zamazinga aphansi e-sodium (ikhanda elibuhlungu, ukugxila enkingeni, izinkinga zenkumbulo)
• Imicabango yokuzilimaza noma ukuzibulala
• Ezimweni ezingavamile, i-fluoxetine ingabangela ukusabela okukhulu kwe-allergic (anaphylaxis). 

Ukuqapha

• Iziguli kufanele zithathe i-fluoxetine kuphela lapho zinqunywe udokotela futhi zilandele umthamo onqunyiwe ngokuqinile. 
• Ukuyeka umuthi kungazelelwe kungaholela emiphumeleni emibi kakhulu. Udokotela angase atusa ukunciphisa kancane kancane umthamo ukuze unciphise izimpawu zokuhoxiswa ezifana nokuyaluza, izinkinga zokuphefumula, ubuhlungu besifuba, ukudideka, isiyezi, nabanye.
• Iziguli kufanele ziqaphele kakhulu lapho zishayela noma zisebenzisa imishini ngemva kokuphuza umuthi. 
• Abantu abane-hypersensitivity eyaziwayo ku-fluoxetine nanoma iyiphi ingxenye ekwakhekeni kwayo kufanele baqaphele.
• Gcina imithi lapho izingane zingakwazi ukufinyelela khona. 
• Iziguli kufanele zazise udokotela wazo ngazo zonke izimo zempilo nemithi eqhubekayo, okuhlanganisa nemithi ethengiswa ezitolo, amavithamini, nezithako zemithi. 
• Abantu abanesifo sikashukela kufanele baqaphele ukuthi i-fluoxetine ingathinta amazinga kashukela egazini. 
• Abesifazane abakhulelwe noma labo abahlela ukukhulelwa kufanele baxoxe ngezingozi nezinzuzo ze-fluoxetine nodokotela wabo. 
• Iziguli ezinokuquleka noma lezo esezikhulile kufanele ziqaphele lapho zisebenzisa lesi sidakamizwa.

Isebenza kanjani ithebhulethi yeFluoxetine

I-Fluoxetine, i-antidepressant enamandla, ingathinta amakhemikhali obuchopho ngokwandisa inani le-serotonin, into engokwemvelo esiza ukugcina ukulinganisela kwengqondo.

Ucwaningo lunikeze ubufakazi obuningi bokuthi i-serotonin idlala indima ebalulekile ekwelapheni ukucindezeleka. Iziguli ezinokucindezeleka zivame ukuba nokugxila okuphansi kwe-serotonin oketshezini lwe-cerebrospinal kanye nezindawo ezimbalwa zokuthatha i-serotonin kumaplatelet azo. I-Fluoxetine ibhekana nalolu daba ngokwandisa amazinga e-serotonin ezingxenyeni ezihlukahlukene zobuchopho.

Ngingakwazi Ukuthatha I-Fluoxetine Neminye Imithi?

• I-Fluoxetine isebenzisana nenani elikhulu lemithi, okwenza kube semqoka ukubonana nodokotela ngaphambi kokuyihlanganisa nezinye izidakamizwa. 
• Kubalulekile ukugwema ukuthatha i-fluoxetine ene-monoamine oxidase (MAO) inhibitors, njenge-isocarboxazid, linezolid, i-methylene blue injection, phenelzine, selegiline, noma i-tranylcypromine. Ukuhlanganisa le mithi kungaholela emiphumeleni emibi kakhulu, okuhlanganisa ukudideka, ukuyaluza, ukungahlaliseki, izimpawu zesisu, izinga lokushisa lomzimba eliphakeme kungazelelwe, noma ukudlikizeka okukhulu.
• I-Thioridazine ne-pimozide, kuhlanganiswe ne-fluoxetine, kungandisa ingozi yezinkinga ezinkulu zenhliziyo. 
• I-Fluoxetine ingase ibangele i-serotonin syndrome lapho ithathwa nemithi ethile. Lokhu kubandakanya:
  • Amphetamine
  • I-Buspirone
  • Fentanyl
  • Lithium
  • I-Tryptophan
  • John's wort
  • Eminye imithi yobuhlungu noma ye-migraine, njenge-meperidine, i-methadone, i-rizatriptan, i-sumatriptan, i-tramadol
  • Iziguli ezithatha i-fluoxetine kufanele ziqaphele lapho zisebenzisa imithi yokunciphisa igazi, kuhlanganise nama-NSAID noma i-warfarin, njengoba i-fluoxetine ingase yandise ingozi yokopha.

Okunye ukusebenzisana okuvame ukuhlolwa ne-fluoxetine kuhlanganisa:

• Ama-antidepressants (isb, i-duloxetine, i-bupropion)
• Ama-Antipsychotics (isb, aripiprazole, quetiapine)
• Imithi yokukhathazeka (isb, i-alprazolam)
• Ukudambisa izinhlungu (isb, i-acetaminophen, i-hydrocodone)
• Izikhuthazi (isb, amphetamine/dextroamphetamine)

Ulwazi Lomthamo

• Kubantu abadala abanokucindezeleka, umthamo wokuqala uvamise ukuba ngu-20 mg kanye ngosuku ekuseni. 
• Ekwelapheni i-bulimia nervosa, abantu abadala bavame ukuthatha ama-60 mg kanye ngosuku ekuseni. 
• Nge-Obsessive-Compulsive Disorder (OCD) kubantu abadala, umthamo wokuqala ngu-20 mg kanye ngosuku ekuseni. 
• Abantu abadala abane-panic disorder ngokuvamile baqala ngo-10 mg kanye ngosuku.
• Nge-premenstrual dysphoric disorder, irejimeni ihilela ukuthatha ama-20 mg nsuku zonke kulo lonke usuku umjikelezo wokuya esikhathini. 

Isiphetho

Ukuguquguquka nokusebenza okuhlukahlukene kwe-Fluoxetine kuguqule ukwelashwa kwezempilo yengqondo ezigidini zabantu emhlabeni jikelele. Nakuba kungelona ikhambi, kubonakale kuyithuluzi elibalulekile ekulawuleni izimo ezehlukene ezingokwengqondo. Njenganoma yimuphi umuthi, ukuxhumana okuvulekile nodokotela kubalulekile ukuze kuqinisekiswe ukusetshenziswa okuphephile nokusebenza ngempumelelo. Ngokuqonda ukuthi i-fluoxetine isebenza kanjani futhi iyisebenzise ngokuzibophezela, iziguli zingathatha izinyathelo ezibalulekile zokuthuthukisa impilo yazo yengqondo kanye nempilo yonke.

FAQ sika

1. I-fluoxetine isetshenziselwa ini ngokuyinhloko?

I-Fluoxetine isetshenziselwa ngokuyinhloko ukwelapha izimo ezihlukahlukene zempilo yengqondo. Kunomthelela ekwelapheni izinhlobo ezahlukene zokucindezeleka, okuhlanganisa nokucindezeleka okukhulu. Odokotela baphinde bayinikeze i-obsessive-compulsive disorder (OCD), ukuphazamiseka kokuphazamiseka, kanye ne-bulimia nervosa. Ukwengeza, i-fluoxetine ibonise ukuphumelela ekwelapheni i-premenstrual dysphoric disorder (PMDD), isimo esifana kodwa esibi kakhulu kune-premenstrual syndrome (PMS).

2. Ubani okufanele aphuze i-fluoxetine?

Abantu abanezimpawu zokucindezeleka, i-OCD, ukuhlaselwa kwesibindi, noma i-bulimia ingase izuze ngokuthatha i-fluoxetine. Odokotela bangase futhi bayincome kubantu abazabalaza ne-PMDD. 

3. Ingabe kufanele ngiphuze i-fluoxetine nsuku zonke?

Ungathatha i-fluoxetine nsuku zonke njengoba kunqunywe udokotela. Ngokuvamile, isetshenziswa kanye ngosuku, kungaba ekuseni noma kusihlwa.

4. Ubani ongakwazi ukuthatha i-fluoxetine?

Abantu abathile akufanele bathathe i-fluoxetine. Lokhu kubandakanya:

• Abantu abangezwani ne-fluoxetine, i-Prozac, nanoma yiziphi izithako zomkhiqizo othile.
• Labo njengamanje abathathayo noma abasanda kuphuza (phakathi kwamasonto amabili edlule) i-monoamine oxidase inhibitors (MAOIs).
• Abantu abane-hypersensitivity eyaziwayo ku-fluoxetine nanoma iyiphi ingxenye ekwakhekeni kwayo

5. Ngingakwazi yini ukuyeka i-fluoxetine noma nini?

Cha, akufanelekile ukuyeka ukuthatha i-fluoxetine kungazelelwe ngaphandle kokubonisana nodokotela wakho. Kungazelelwe, ukuyeka umuthi kungaholela ezimpawini zokuhoxa, ezaziwa nangokuthi i-antidepressant discontinuation syndrome. Lezi zimpawu zingase zihlanganise ukukhathazeka, ukucasuka, ukushintshashintsha kwemizwelo, ikhanda elibuhlungu, isiyezi kanye nezimpawu ezinjengomkhuhlane. 

6. Yimuphi umphumela ovame kakhulu we-fluoxetine?

Imiphumela emibi evame kakhulu ebikwe abantu abadala ihlanganisa:

• Ukuqwasha noma izinguquko emaphethini okulala
• I-nausea
• Ukuphathwa yikhanda
• Uhudo
• Umlomo omile
• Ukunciphisa ukudla
• Ukukhathazeka noma ukwesaba
• Ukuphoqa

7. Ingabe i-fluoxetine isetshenziselwa ukucindezeleka?

Nakuba i-fluoxetine inganqunyelwe ngokuyinhloko ukucindezeleka kuphela, ingasiza ukuphatha izimo ezivame ukuhlotshaniswa nokucindezeleka, njengokucindezeleka nokukhathazeka kokukhathazeka. 

Umshwana wokuzihlangula: Ulwazi olunikezwe lapha alwenzelwe ukufaka iseluleko esivela kuchwepheshe wezokunakekelwa kwempilo. Ulwazi aluhloselwe ukumboza konke ukusetshenziswa okungenzeka, imiphumela engemihle, izinyathelo zokuphepha, nokusebenzisana kwezidakamizwa. Lolu lwazi aluhloselwe ukuphakamisa ukuthi ukusebenzisa umuthi othile kufanelekile, kuphephile, noma kuyasebenza wena noma omunye umuntu. Ukungabi bikho kwanoma yiluphi ulwazi noma isexwayiso mayelana nomuthi akufanele kuhunyushwe njengesiqinisekiso esicacile esivela enhlanganweni. Sikweluleka ngokuqinile ukuthi uthintane nodokotela uma kukhona okukukhathazayo ngomuthi futhi ungalokothi usebenzise umuthi ngaphandle kwencwadi kadokotela.