I-Hydrocodone

I-Hydrocodone

Isidakamizwa i-Hydrocodone, isidakamizwa esinamandla se-opioid, sesiyisinqumo esivamile sokuphatha ubuhlungu obumaphakathi kuya kobunzima. Lo muthi, otholakala njengethebhulethi noma usesimweni esiwuketshezi, udlala indima ebalulekile ekulawulweni kwezinhlungu ezigidini zabantu emhlabeni jikelele. Ukuqonda ukusetshenziswa kwawo, imiphumela, kanye nezingozi ezingaba khona kubalulekile kunoma ubani ocabangayo noma osebenzisa lesi sidakamizwa njengamanje.

Iyini iHydrocodone?

IHydrocodone umuthi wezinhlungu wenarcotic onamandla osetshenziselwa ukwelapha ubuhlungu obumaphakathi kuya kobunzima. Ingokwesigaba sezidakamizwa ezaziwa ngokuthi i-semi-synthetic opioid, okusho ukuthi iphuma ku-codeine, into eyenzeka ngokwemvelo etholakala ku-opium poppy. Lo muthi uthole ukunakwa okuphawulekayo emkhakheni wezokwelapha ngenxa yokuphumelela kwawo ekulawuleni izinhlobo ezihlukahlukene zobuhlungu.

Njengomuthi weSheduli II, i-hydrocodone ingaphansi kwemithetho eqinile nemihlahlandlela ngenxa yamandla ayo okuhlukumeza nokuncika. Odokotela banikeza lo muthi lapho ezinye izindlela ezingezona i-opioid zehluleka ukunikeza ukukhululeka kobuhlungu okwanele. 

Ukusetshenziswa kwe-Hydrocodone Tablet

Ukusetshenziswa okuyinhloko kwamaphilisi e-hydrocodone kuhlanganisa:

• Ukuphatha ubuhlungu obumaphakathi kuya kobunzima obukhulu
• Ukwelapha ubuhlungu be-flare-up ezigulini ezinezimo ezingapheli
• Ukubhekana nezimpawu zomkhuhlane ojwayelekile kanye i-allergic rhinitis (ngokuhambisana neminye imithi)
• Ukucindezela ukukhwehlela okungakhiqizi (yize kungavamile manje)

Kubalulekile ukuqaphela ukuthi i-hydrocodone isidakamizwa seSheduli II. Ibonisa amandla ayo aphezulu okuhlukunyezwa nokuncika. Odokotela bahlola ngokucophelela izidingo zesiguli ngasinye ngaphambi kokunikeza amaphilisi e-hydrocodone, baqinisekise ukuthi lo muthi onamandla usetshenziswa ngendlela efanele nangempumelelo.

Isetshenziswa kanjani i-Hydrocodone Tablet

Ukusebenzisa amaphilisi e-hydrocodone ngendlela efanele:

• Thatha imithi njengoba uyalelwe udokotela wakho. Ungathathi okungaphezu kokuqondisiwe, kaningi, noma isikhathi eside kunoku-oda.
• Sebenzisa amaphilisi ngesikhathi esifanayo nsuku zonke, ngokudla noma ngaphandle kokudla.
• Geza ithebhulethi yokukhishwa okunwetshiwe iyonke. Ungayichobozi, ungayiphuli, uyihlafune, noma uyincibilikise.
• Gwema ukucwiliswa ngaphambili, ukukhotha, noma ukumanzisa ithebhulethi ngaphambi kokuyibeka emlonyeni.
• Thatha iphilisi elilodwa ngesikhathi nenani elanele lamanzi ukuze uqinisekise ukugwinya okuphelele ngokushesha ngemva kokulibeka emlonyeni.

Imiphumela Emibi Yethebhulethi ye-Hydrocodone

Imiphumela emibi evamile ngokuvamile engadingi ukungenelela kwezokwelapha ihlanganisa:

• ukuqunjelwa
• isiyezi
• Ukulala
• Umlomo omile
• bekhanda
• I-nausea
• Inkinga yokulala
• Isihlungu esiswini
• Ukuvota

Imiphumela Emibi Kakhudlwana Eyengeziwe:

• Ukuphendula kwe-allergen
• Ukucindezeleka kwe-CNS kubonakala njengokuphefumula kancane noma okungajulile, ukuphelelwa umoya, ukuzwa ukuquleka, isiyezi, ukudideka, noma inkinga yokuhlala uphapheme.
• Ukulimala kwesibindi kubonisa izimpawu ezifana nobuhlungu besisu esingenhla kwesokudla, ukulahlekelwa ukudla, isicanucanu, indle enombala okhanyayo, umchamo onsundu ngokumnyama noma onsundu, isikhumba esiphuzi noma amehlo, nokuba buthakathaka okungavamile noma ukukhathala.
• Ukungasebenzi kahle kwezindlala ze-adrenal kubangela isicanucanu, ukuhlanza, ukuphelelwa ukudla, ubuthakathaka obungavamile noma ukukhathala, kanye nesiyezi.
• Umfutho wegazi ophansi

Ukuqapha

Ukuthatha umuthi i-hydrocodone kudinga ukucatshangelwa ngokucophelela nokuhambisana nezinyathelo ezithile zokuphepha. 

• Iziguli kufanele zazise udokotela kanye nosokhemisi mayelana nanoma yikuphi ukungezwani ne-hydrocodone, eminye imithi, noma izithako ezikumaphilisi noma amaphilisi akhululiwe e-hydrocodone. 
• Ngaphambi kokuqala i-hydrocodone, iziguli kufanele zidalule ukuthi ziyayithatha yini noma zisanda kuyeka ukuthatha imithi ethile. Lokhu kufaka phakathi i-isocarboxazid, i-linezolid, i-methylene eluhlaza okwesibhakabhaka, i-phenelzine, i-selegiline, noma i-tranylcypromine.
• Labo abanomfutho wegazi ophansi, ubunzima bokuchama, ukungasebenzi kahle kwezindlala ze-adrenal, isifo sikashukela, ukuquleka, noma i-thyroid, inyongo, amanyikwe, isibindi, noma izimo zezinso kufanele zazise udokotela wabo. 
• Iziguli ezinezimo ezithile, ezinjengokuncipha noma ukuvaleka kwesisu noma amathumbu noma ileus ekhubazekile, kufanele futhi zazise udokotela wazo, njengoba zingase zelulekwe ngokumelene nokuthatha i-hydrocodone.
• Okhulelwe futhi ibele omama kufanele bakugweme ukusebenzisa i-hydrocodone. 
• Iziguli kufanele ziqaphele ukuthi i-hydrocodone ingase yehlise ukuzala kwabesilisa nabesifazane. 
• Lapho zihlinzwa, okuhlanganisa nezinqubo zamazinyo, iziguli kufanele zazise udokotela wazo noma udokotela wamazinyo mayelana nokusebenzisa kwazo i-hydrocodone. 
• Umuthi ungase ubangele ukozela, kuphazamise ikhono lokushayela noma ukusebenzisa imishini.
• IHydrocodone ingase ibangele isiyezi, ikhanda elilula, nokuquleka lapho isukuma ngokushesha endaweni elele kuyo. 

Isebenza kanjani i-Hydrocodone Tablet

Amaphilisi e-Hydrocodone asebenza ngokuvula ama-opioid receptors ohlelweni lwezinzwa olumaphakathi (CNS), okuholela ekudambiseni ubuhlungu, ukudambisa, neminye imiphumela. Ukusebenzisana kwayo okuyinkimbinkimbi nezindlela ezihlukahlukene ze-neural kunomthelela ekusebenzeni kwayo njengomuthi wezinhlungu kodwa futhi namandla ayo okuba nemiphumela emibi kanye nokuncika.

Ngingakwazi Ukuthatha I-Hydrocodone Neminye Imithi?

Lapho uthatha i-hydrocodone, iziguli kufanele zazise udokotela wazo ngayo yonke imithi eziyisebenzisayo njengamanje noma ezihlela ukuyiphuza. Lokhu kuhlanganisa imithi kadokotela, imithi engagunyaziwe, amavithamini, izithasiselo zokudla okunomsoco, nemikhiqizo yamakhambi. Udokotela angase adinge ukulungisa imithamo noma aqaphe isiguli eduze ukuze aqinisekise ukuphepha.

Eminye imithi ingandisa ingozi yemiphumela emibi kakhulu noma esongela ukuphila uma ihlanganiswa ne-hydrocodone. Lokhu kubandakanya:

• Ama-Antihistamine
• Benzodiazepines
• I-Barbiturates
• I-Cimetidine
• Ama-depressants wesistimu yezinzwa emaphakathi (CNS).
• Umuthi wokulala nokukhathazeka
• Ama-relaxant muscle
• Amanye ama-opioid
• Phenytoin
• Rifampin
• URitonavir

Ulwazi Lomthamo

Kuma-capsules akhululiwe isikhathi eside, abantu abadala be-opioid-naive ngokuvamile baqala ngo-10 mg njalo emahoreni ayi-12 ngenxa yobuhlungu obukhulu. Ezigulini ezingabekezeleli i-opioid-naive noma i-opioid-opioid, ngokuvamile odokotela baqala i-hydrocodone ER ngo-10 kuya ku-20 mg njalo emahoreni ayi-12 kuya kwangu-24, kuye ngokwakhiwa okuqondile. 

Isiphetho

IHydrocodone inomthelela omkhulu ekulawulweni kobuhlungu, enikeza impumuzo kulabo ababhekene nokungakhululeki okumaphakathi kuya kokunzima. Ikhono layo lokusebenzelana nama-opioid receptors omzimba liholela ekulawuleni ubuhlungu obusebenzayo, kodwa futhi iza nezingozi nemiphumela engemihle. Ukuqonda ukuthi ungawusebenzisa kanjani lo muthi ngendlela efanele, okuhlanganisa umthamo olungile kanye nezinyathelo zokuphepha ezidingekayo, kubalulekile ezigulini nakodokotela.

FAQ sika

1. I-hydrocodone isetshenziselwa ini ngokuyinhloko?

IHydrocodone inomthelela omkhulu ekulawulweni kobuhlungu. Odokotela banikeza lo muthi onamandla we-opioid ukuze udambise ubuhlungu obumaphakathi kuya kobunzima. 

2. Ubani okufanele aphuze i-hydrocodone?

IHydrocodone inqunyelwe abantu abahlangabezana nalokhu:

• Ubuhlungu obukhulu obuqala ngokuzumayo futhi bunembangela ethile
• Ubuhlungu obungapheli okulindeleke ukuthi budinge ukwelashwa kwe-opioid yesikhathi eside
• Ubuhlungu obungakwazi ukulawulwa ngenye imithi yezinhlungu

3. Ngingakwazi yini ukuphuza i-hydrocodone nsuku zonke?

Isinqumo sokuthatha i-hydrocodone nsuku zonke sincike encwadini kadokotela kanye nezidingo zesiguli. Kulabo abanobuhlungu obukhulu obungapheli, ukusetshenziswa kwansuku zonke kungase kudingeke. Nokho, kubalulekile ukulandela imiyalelo kadokotela ngokuqondile.

4. Ubani ongakwazi ukuthatha i-hydrocodone?

Amaqembu amaningana abantu kufanele aqaphele noma agweme ukuthatha i-hydrocodone:

• Abantu abanezinkinga zokuphefumula: Abantu abanokuphefumula okunensayo, abanzima ufuba, noma Izifo Ezingalapheki Ezivimbela Amaphaphu (COPD) 
• Iziguli ezinezimo ezithile zezokwelapha: Labo abanomlando wokulimala ekhanda, izimila ebuchosheni, noma izimo ezandisa ukucindezela kwe-intracranial kufanele bazise udokotela wabo ngaphambi kokuthatha i-hydrocodone.
• Abesifazane abakhulelwe noma abancelisa ibele: I-Hydrocodone ingabangela imiphumela emibi kakhulu ezinganeni ezisanda kuzalwa, okuhlanganisa izimpawu zokuhoxa kanye nobunzima bokuphefumula.
• Abantu abanomlando wokusebenzisa kabi izidakamizwa: Ngenxa yamandla ayo okuba umlutha, i-hydrocodone ingase ingafaneleki kubantu abanomlando womuntu siqu noma womndeni wokuphazamiseka kokusetshenziswa kwezidakamizwa.
• Iziguli ezinezinkinga ezithile zokugaya ukudla: Labo abanokuncipha kwesisu noma amathumbu kufanele bagweme i-hydrocodone.
• Abantu abanesifo sesibindi noma sezinso: Lezi ziguli zingadinga ukulungiswa komthamo noma ezinye izindlela zokwelapha.

5. Ngingakwazi yini ukumisa i-hydrocodone noma nini?

Ukumisa kungazelelwe i-hydrocodone akunconywa, ikakhulukazi kulabo asebeyiphuze isikhathi eside noma ngemithamo ephezulu. Ukuyekiswa ngokuzumayo kwe-hydrocodone kungaholela ezimpawu zokuhoxa, ezingabandakanya:

• Ukuphumula
• Amehlo acwebile nekhala eligelezayo
• Ezamula ejuluka
• Ukugodola nobuhlungu bemisipha
• ukukhathazeka nokucasuka
• Amajaqamba esiswini kanye nesifo sohudo
• I-nausea nokuhlanza
• Ukuphefumula okusheshayo nokukhuphuka kwenhliziyo

6. Kungani uphuza i-hydrocodone ebusuku?

Nakuba isikhathi esiqondile somthamo we-hydrocodone sincike ebhalweni kanye nezidingo zesiguli, ukuyithatha ebusuku kunganikeza izinzuzo ezimbalwa:

• Imithamo yasebusuku ingasiza ekulawuleni ubuhlungu obungase buphazamise ukulala.
• Njengoba i-hydrocodone ingabangela ukozela, ukuyithatha ebusuku ihambisana nomjikelezo wokulala wemvelo womzimba.
• Ngokuphuza imithi ebusuku, iziguli zingase zibe nobuthongo obuncane emini kanye nokukhubazeka kwengqondo.

Umshwana wokuzihlangula: Ulwazi olunikezwe lapha alwenzelwe ukufaka iseluleko esivela kuchwepheshe wezokunakekelwa kwempilo. Ulwazi aluhloselwe ukumboza konke ukusetshenziswa okungenzeka, imiphumela engemihle, izinyathelo zokuphepha, nokusebenzisana kwezidakamizwa. Lolu lwazi aluhloselwe ukuphakamisa ukuthi ukusebenzisa umuthi othile kufanelekile, kuphephile, noma kuyasebenza wena noma omunye umuntu. Ukungabi bikho kwanoma yiluphi ulwazi noma isexwayiso mayelana nomuthi akufanele kuhunyushwe njengesiqinisekiso esicacile esivela enhlanganweni. Sikweluleka ngokuqinile ukuthi uthintane nodokotela uma kukhona okukukhathazayo ngomuthi futhi ungalokothi usebenzise umuthi ngaphandle kwencwadi kadokotela.