I-Loratadine

I-Loratadine

Ukuthimula, ukulunywa, namehlo agcwele amanzi kungenza usuku oluhle lube usuku oludabukisayo kwabagulayo. I-Loratadine, i-antihistamine esetshenziswa kakhulu, inikeza ukukhululeka kulezi zimpawu ezikhathazayo. Lo muthi usuthole ukuthandwa ngokuba ngesinye sezidakamizwa ezisebenza kahle kakhulu ekwelapheni izimo ezahlukahlukene zokungezwani komzimba ngaphandle kokubangela ukozela, okwenza kube yinketho kubantu abaningi abafuna impumuzo yokungezwani nomzimba. Ake sihlole ukusetshenziswa kwamaphilisi e-loratadine, umthamo, kanye nemiphumela engemihle engaba khona.

Iyini i-Loratadine?

I-Loratadine iyi-antihistamine engeyona eyozela, yesizukulwane sesibili. Ivimbela isenzo se-histamine emzimbeni, into ebangela ukungezwani komzimba. Ngokungafani namanye ama-antihistamine, i-loratadine ibangela ukozela okuncane, okuyenza ifanelekele ukusetshenziswa emini. 

Ukusetshenziswa kwe-Loratadine

I-Loratadine isiza ekulawuleni izimpawu ezihlukahlukene zokungezwani komzimba:

• Lo muthi we-antihistamine ukhulula ngempumelelo izinkinga ezijwayelekile njengekhala eligijima, Amehlo amanzi, ukulunywa, nokuthimula. Lezi zimpawu zivame ukubangelwa i-hay fever kanye nokunye ukungezwani nezinto ezifana nempova, uthuli, noma izinto ezicasula emoyeni.
• I-Loratadine isiza abantu ukuthi babhekane nokungezwani komzimba ngezikhathi ezithile zonyaka.
• Omunye wezidakamizwa ezibalulekile ezisetshenziswayo i-loratadine ukwelapha ukulunywa kanye nokubabomvu okubangelwa ama-hives. Kodwa-ke, kubalulekile ukuqaphela ukuthi akuvimbeli isifuba noma okunye ukungezwani kwesikhumba ukuthi kwenzeke.

Kubalulekile ukuqonda ukuthi abantu akufanele nanini basebenzise i-loratadine esikhundleni se-epinephrine ekwelapheni ukusabela okweqile kwe-allergic noma i-anaphylaxis.

Indlela yokusebenzisa i-Loratadine

I-Loratadine iza ngezinhlobo ezahlukene, okuhlanganisa amaphilisi, amaphilisi ahlukanisayo ngomlomo (ama-ODT), amaphilisi ahlafunwayo, amaphilisi agcwele uketshezi, kanye nesiraphu. 

• Abantu bangayithatha ngokudla noma ngaphandle kokudla, kodwa kungcono kakhulu ukuphuza imithi yomlomo esiswini esingenalutho.
• Uma usebenzisa ama-ODT, beka ithebhulethi olimini bese uyivumela ukuthi incibilike. Ingagwinywa ngamanzi noma ngaphandle kwayo. 
• Ukuze uthole ukwakheka okuwuketshezi, sebenzisa inkomishi yomthamo enikeziwe ukuze ulinganise ngokunembile.
• Iziguli ezinezinso noma zesibindi zingase zidinge ukulungisa isimiso sazo somthamo.
• Kubalulekile ukugcina i-loratadine ekamelweni lokushisa. Yigcine kude nezingane, futhi ugweme ukuqanda imithi.
• Iziguli kufanele zigweme ukushayela izimoto noma ukusebenzisa noma yimuphi umshini uma ukozela kwenzeka kuze kube yilapho ziqonda ukuthi umuthi uzithinta kanjani. 
• Ngaso sonke isikhathi landela iziqondiso zikadokotela noma iziqondiso zephakheji yomkhiqizo ngokucophelela. Uma izimpawu ziqhubeka ngemva kwezinsuku ezimbalwa zomuthi noma ziba zimbi, thintana nodokotela.

Imiphumela emibi ye-Loratadine Tablet

I-Loratadine ngokuvamile inephrofayili yokuphepha enhle, kodwa ingabangela imiphumela emibi kwabanye abantu. Imiphumela emibi evamile ye-loratadine ihlanganisa:

• bekhanda
• Umlomo omile
• Ukukhathala
• Ukulala
• Ubuhlungu besisu
• Uhudo

Ezimweni ezingavamile, i-loratadine ingase ibangele imiphumela emibi kakhulu. Lokhu kungafaka:

• I-Rash noma i-hives
• Itching
• Ukuvuvukala kobuso, amehlo, izindebe, ulimi, noma umphimbo
• Ubunzima bokuphefumula noma ukugwinya
• Ukuthuthumela
• Ukushisa

Ukuqapha

Iziguli kufanele ziqaphele lapho zisebenzisa i-loratadine, njenge: 

• Labo abane-hypersensitivity ebhaliwe yomuthi noma izingxenye zawo kufanele bakugweme. 
• Izingane ezingaphansi kweminyaka emibili ubudala akufanele zithathe i-loratadine ngenxa yokuvuselela isimiso sezinzwa esimaphakathi noma ukuquleka.
• Abantu abane-asthma noma i-COPD kudingeka basebenzise i-loratadine ngokucophelela, njengoba imiphumela yayo ye-anticholinergic ingase ibangele ukuvutha. 
• Nakuba ngokuvamile kungalalisi, abanye abantu bangase babe nobuthongo. Ngakho-ke, iziguli kufanele ziqaphele lapho zishayela noma zenza imisebenzi edinga ukugxilisa ingqondo.
• Abantu abane-phenylketonuria (PKU) kufanele babonane nodokotela wabo ngaphambi kokuthatha i-loratadine, njengoba ezinye izithako zingase zibe ne-phenylalanine. 
• abesifazane abakhulelwe ungasebenzisa ngokuphepha i-loratadine. Kodwa-ke, omama abancelisayo kufanele bayisebenzise ngokucophelela futhi isikhathi esifushane kuphela, njengoba i-loratadine kanye ne-metabolite yayo esebenzayo idlula ubisi lwebele.
• Abantu abadala asebekhulile bangase babe sengozini yemiphumela yayo emibi. 
• Iziguli ezinesifo sikashukela kufanele ziqaphele ukuthi eminye imikhiqizo ye-loratadine ewuketshezi noma ehlafunwayo ingase ibe noshukela.

I-Loratadine Isebenza Kanjani?

I-Loratadine iyi-antihistamine yesizukulwane sesibili ehlose ama-receptors we-peripheral H1. Lawa ma-receptors atholakala emangqamuzaneni ahlukahlukene, kuhlanganise nalawo asohlelweni lokuphefumula, imithambo yegazi, namasosha omzimba. Lapho i-histamine ibophezela kulawa ma-receptors, yenza izimpawu zokungezwani komzimba zisebenze. I-Loratadine isebenza ngokuncintisana ne-histamine kulezi zindawo ezibophayo kanye nokunciphisa ukuqina kwezimpawu zokungezwani komzimba nezinto ezithile.

Ngokungafani nama-antihistamine esizukulwane sokuqala, i-loratadine ayiweli kahle umgoqo wegazi nobuchopho. Lokhu kusho ukuthi umuthi unokuhlobana okuphansi kwama-H1 receptors ku-CNS (uhlelo lwezinzwa olumaphakathi). Ngenxa yalokho, akubangeli ukozela noma ukuphazamisa ukusebenza kwengqondo, okwenza kube ukukhetha okuncanyelwayo ukusetshenziswa kwasemini.

Ngingathatha I-Loratadine Ngeminye Imithi?

I-Loratadine isebenzisana nemithi eminingi, ngakho-ke kubalulekile ukuqapha lapho uyihlanganisa nezinye izidakamizwa. 

Eminye imithi evamile engase ihlanganyele ne-loratadine ihlanganisa:

• I-Acetaminophen
• I-Alprazolam
• I-Apixaban Aspirin
• Ama-CNS depressants afana ne-diphenhydramine noma i-pseudoephedrine 
• I-diphenhydramine
• I-Duloxetine
• I-Escitalopram
• I-Metoprolol
• I-Sertraline

Ulwazi Lomthamo

Umthamo we-Loratadine uncike eminyakeni yesiguli, isimo, kanye nokwakheka. Abantu abadala kanye nezingane izinyanga ezingama-72 (iminyaka engu-6) nangaphezulu: 

• Umthamo ojwayelekile ungamamiligremu ayi-10 kanye ngosuku. Lokhu kulinganisa kusebenza kukho konke ukwakheka, okuhlanganisa amaphilisi, ama-ODT, namaphilisi agcwele uketshezi. 
• Izingane ezineminyaka emi-2 kuya kwemi-5: Umthamo ojwayelekile ngu-5 mg kanye ngosuku, ngokuvamile kusiraphu.
• Kubalulekile ukuhlala ngaphakathi kwethamo elinconyiwe lansuku zonke. Abantu abadala kanye nezingane akufanele bathathe ngaphezu kwe-10 mg emahoreni angama-24, kanti izingane ezingaphansi kwesithupha akufanele zidlule ku-5 mg emahoreni angama-24.

Isiphetho

I-Loratadine isiza ukuphatha izimpawu ezihlukahlukene zokungezwani komzimba, inikeza impumuzo ngaphandle kokubangela ukozela. Le antihistamine ibhekana ngokuphumelelayo nezindaba ezivamile ezifana nokuthimula, ikhala eligijimayo, namehlo alumayo, okwenza kube ukukhetha okuthandwayo kubantu abaningi abanokungezwani komzimba nezinto ezithile. Ukuguquguquka kwayo ekwelapheni izimo ezahlukahlukene zokungezwani komzimba kanye nephrofayili yayo enhle yokuphepha kuyenze yaba inketho ethandwayo kubantu abadala nasezinganeni.

Nakuba i-loratadine ngokuvamile iphephile futhi isebenza ngempumelelo, kubalulekile ukuyisebenzisa njengoba uyalwe udokotela wakho futhi uqaphele izinkinga ezingase zibe khona kanye nokusebenzisana. Khumbula, i-loratadine ayifaki esikhundleni semithi ephuthumayo yokungezwani komzimba, futhi abantu abane-allergies enzima kufanele bahlale bephethe i-epinephrine injector yabo enqunyiwe.

FAQ sika

1. Ingabe i-loratadine ingcono kune-cetirizine?

I-Loratadine ne-cetirizine womabili ama-antihistamine angawozeli asebenzayo asebenza ngendlela efanayo ekwelapheni izimpawu zokungezwani komzimba nezinto ezithile. Kodwa-ke, i-loratadine ne-desloratadine abonakala emancane amathuba okuba abangele ukozela cetirizine. Abanye abantu bangathola ukuthi omunye ubasebenzela kangcono kunomunye. Udokotela wakho uzokunikeza inketho engcono kakhulu ngokusekelwe kuzimpawu zakho ezithile.

2. Iphephile ngani i-loratadine?

I-Loratadine iphatha ngokuphepha izimpawu zokungezwani nokuphefumula okuphezulu, njenge-hay fever. Ikhulula ukuthimula, ikhala eligijimayo, ikhala elilumayo noma umphimbo, namehlo agcwele amanzi. I-Loratadine iyasiza futhi ngokulunywa yizinyosi. Ngokuvamile kuphephile kubantu abadala kanye nezingane ezingaphezu kweminyaka emibili ubudala. Kodwa-ke, ayijwayele ukusetshenziselwa ukungezwani komzimba nesikhumba kodwa ingadambisa ukulunywa kusuka ezidlekeni.

3. Ingabe i-loratadine iphephile ezinso?

Abantu abanenkinga yezinso kufanele basebenzise i-loratadine ngokucophelela. Izinso zisiza ukususa i-loratadine emzimbeni, ngakho uma zingasebenzi kahle, umuthi ungakheka, okwandisa ingozi yemiphumela engemihle. Uma unenkinga yezinso, thintana nodokotela wakho ngaphambi kokuthatha i-loratadine. Bangase balungise umthamo wakho ngokwezidingo zakho.

4. Ngingakwazi yini ukuthatha i-loratadine ebusuku?

Yebo, ungathatha i-loratadine ebusuku. I-antihistamine engakozeli, ngakho-ke mancane amathuba okuthi ikwenze ulale kunama-antihistamine amadala, athobayo. Kodwa-ke, abanye abantu basengaba nakho ukozela, ngakho-ke kungcono ukubona ukuthi kukuthinta kanjani ngaphambi kokushayela noma ukusebenzisa imishini.

5. Ingabe kufanele ngiphuze i-loratadine ebusuku noma ekuseni?

Ungathatha i-loratadine nganoma yisiphi isikhathi sosuku. Kodwa-ke, uma uthatha isikhathi esingaphezu kosuku olulodwa, kungcono ukuyithatha ngesikhathi esifanayo usuku ngalunye ukuze ulondoloze ukusebenza kahle okungaguquki. Abanye abantu bancamela ukuyiphuza ekuseni ukuze baqinisekise ukuthi abathinteki kunoma yikuphi ukozela okungaba khona phakathi nosuku.

6. Ingabe i-loratadine ilungele ukukhwehlela?

I-Loratadine ayisetshenziselwa ukwelapha ukukhwehlela. Isetshenziselwa ikakhulukazi izimpawu zokungezwani komzimba ezifana nokuthimula, ikhala eligijimayo, namehlo alumayo. Uma unokukhwehlela okuhlobene ne-allergies, i-loratadine ingasiza ngokunciphisa izimpawu zokungezwani komzimba jikelele, kodwa akuyona into ecindezela ukukhwehlela.

7. Ngingakwazi yini ukuthatha i-loratadine nsuku zonke?

Yebo, ungathatha i-loratadine nsuku zonke, ikakhulukazi ngezikhathi zokungezwani komzimba. Uma udinga ukuyithatha nsuku zonke isikhathi eside, thintana nodokotela wakho ukuze uqinisekise ukuthi iyisixazululo sesikhathi eside esingcono kakhulu sezimpawu zakho zokungezwani komzimba nezinto ezithile.