I-Lorazepam

I-Lorazepam

Sonke sike saba nezikhathi zokukhathazeka noma zokungalali ngesikhathi esithile ezimpilweni zethu. Yilapho i-lorazepam iqala khona ukusebenza. Lo muthi onamandla uthole ukuqashelwa ngokusebenza kwawo ekulawuleni ukuphazamiseka kokukhathazeka nezinkinga zokulala. 

Ake sihlolisise ukuthi iyini i-lorazepam nokuthi isebenza kanjani emzimbeni. Sizoxoxa ngezindlela ezihlukahlukene ezisetshenziswa ithebhulethi ye-lorazepam 2mg, okuhlanganisa nendima yayo ekwelapheni ukukhathazeka futhi njengosizo lokulala. 

Iyini i-Lorazepam?

Umuthi we-Lorazepam umuthi onamandla ongokwesigaba sezidakamizwa ezibizwa ngokuthi i-benzodiazepines. Ithonya ubuchopho nezinzwa, ikhiqize umphumela wokuzola. Sisebenzisa amaphilisi e-lorazepam ukwelapha izimo ezihlukahlukene, kuhlanganise nokuphazamiseka kokukhathazeka, ukuphazamiseka kovalo, nezinye izifo zokuquleka njengesithuthwane. Lesi sidakamizwa sithuthukisa imiphumela ye-GABA, ikhemikhali yemvelo emzimbeni wethu. Kubalulekile ukuqaphela ukuthi i-lorazepam isebenza ngokunciphisa umsebenzi wobuchopho, okuvumela ukuphumula nokunciphisa izimpawu zokukhathazeka. 

Ukusetshenziswa kwethebhulethi ye-Lorazepam

Sisebenzisa amaphilisi e-lorazepam ngezinjongo ezihlukahlukene. Ukusetshenziswa kwe-lorazepam okugunyazwe yi-FDA yilezi:

• Ukukhululeka kwesikhashana kokubonakaliswa kokukhathazeka okuhlobene nokuphazamiseka kokukhathazeka. 
• Okuhambisana nokukhathazeka ukuqwasha.
• I-Lorazepam inethonya ekusetshenzisweni kwangaphambili kwe-anesthesia kubantu abadala, isiza ekudambiseni ukukhathazeka noma yenze i-sedation kanye amnesia. 
• Odokotela baphinde basebenzise amaphilisi e-lorazepam ukuze belaphe i-status epilepticus, isimo sokuquleka esinzima. 

Ukusetshenziswa ngaphandle kwelebula yilezi:

• Isicanucanu nokuhlanza okuhambisana ne-Chemotherapy
• Ukuphatha i-alcohol withdrawal syndrome
• Ama-spasms we-muscle
• Insomnia
• Ukuthula okusheshayo kweziguli eziyaluza
• Iziyaluyalu zokwethuka
• I-Psychogenic catatonia

Ungayisebenzisa kanjani i-Lorazepam Tablets

Abantu bahlala bethatha i-lorazepam ngokuqondile njengoba udokotela wabo eyalile. 

• Umuntu ngamunye kufanele aphuze amaphilisi e-lorazepam ngesiphuzo samanzi, ngokudla noma ngaphandle kokudla. Umthamo uncike esimweni sezempilo somuntu, iminyaka, kanye nendlela asabela ngayo ekwelashweni. 
• Geza ithebhulethi ye-lorazepam iphelele ngaphandle kokuyiphula, ukuyichoboza, noma ukuyihlafuna. 
• Uma usebenzisa i-lorazepam njalo, yithathe kanyekanye (izi)suku ngalunye ukuze uthole inzuzo enkulu. 
• Kubalulekile ukuthi ungayeki ngokuzumayo ukusebenzisa i-lorazepam ngaphandle kokubonisana nodokotela wethu, njengoba ezinye izimo zingase zibe zimbi kakhulu lapho umuthi umiswa kungazelelwe.
• Ukusebenzisa lo muthi isikhathi eside kungase kuwenze ungasebenzi. Xhumana nodokotela wakho uma lo muthi ungasasebenzi ngendlela owawusebenza ngayo.

Imiphumela Emibi ye-Lorazepam Tablets

Amaphilisi e-Lorazepam angaba nomthelela kubantu ngezindlela ezahlukahlukene. Imiphumela emibi evamile ihlanganisa: 

• Ukulala
• isiyezi
• I-Hypotension
• Ukungabi namandla
• Ukuphathwa yikhanda
• Umbono ophundlekile
• Izinkinga zokusebenzisana
• Ukudideka noma inkinga ngenkumbulo
• I-Libido iyashintsha
• Ukuya esikhathini okungajwayelekile 
• Izimpawu zokutheleleka, njengomphimbo obuhlungu noma umkhuhlane
• Isifiso sokudla siyashintsha noma ukuqunjelwa

Imiphumela emibi kakhulu, nakuba ingavamile, ingenzeka, njenge: 

• Ukucindezeleka kokuphefumula nokwehluleka
• I-Tachycardia
• Ukucindezeleka
• Imicabango yokuzibulala
• Ingozi eyengeziwe yokusetshenziswa kabi nokulutha okuhlobene ne-lorazepam
• Ukusabela okuyindida, njengokuziphatha ngokweqile kanye nolaka

Ukuqapha

Abantu kufanele bathathe izinyathelo zokuphepha ezithile lapho besebenzisa amaphilisi e-lorazepam, njenge: 

• Ukuqapha Kwezokwelapha: Kubalulekile ukwazisa udokotela wakho mayelana ne-allergies yakho, ikakhulukazi i-benzodiazepines noma eminye imithi. Abantu ngabanye baphinde batshele udokotela wabo ngawo wonke umlando wezokwelapha oqhubekayo ukuze bagweme noma yikuphi ukusebenzisana kwezidakamizwa.
• Umlando Wezokwelapha: Abantu kufanele futhi badalule umlando wabo wezokwelapha, ikakhulukazi uma benesifo sezinso noma sesibindi, i-glaucoma, izinkinga zokuphefumula, izinkinga zempilo yengqondo, noma umlando wokuphazamiseka kwezidakamizwa. 
• Isexwayiso Sokozela: I-Lorazepam ingase ibangele ukozela noma isiyezi, ngakho-ke abantu kufanele bakugweme ukushayela imoto noma ukusebenzisa imishini. Kufanele futhi bagweme utshwala ngenkathi bethatha lo muthi. 
• Abadala: Kubantu abadala asebekhulile, i-lorazepam ingaba nomphumela ophakeme, okwandisa ingozi yokuwa. 
• Ukukhulelwa: abesifazane abakhulelwe kufanele uqaphele ukuthi i-lorazepam ingalimaza usana olungakazalwa futhi ingase ibangele ngisho nezimpawu zokuhoxa ezinganeni ezisanda kuzalwa. Ngakho-ke, kubalulekile ukuxoxa ngezinkinga nezinzuzo nodokotela wethu uma sikhulelwe noma sihlela ukukhulelwa.
• Ukumisa: I-Lorazepam idlula ubisi lwebele, ngakho thintana nodokotela wakho ngaphambi kokuncelisa.

Isebenza kanjani ithebhulethi ye-Diazepam

I-Lorazepam, i-benzodiazepine, inethonya elikhulu ohlelweni lwezinzwa oluphakathi. Inamathela kuma-receptors athile ebuchosheni, ithuthukisa imiphumela ye-GABA, ikhemikhali yemvelo ethulisa ukusebenza kwezinzwa. Lokhu kubophezela kubangela ukwanda kokugeleza kwama-ion e-chloride ngaphakathi kwamaseli, okubangela i-hyperpolarisation & nokuzinza kwe-membrane ye-plasma yeselula. Lokhu kubangela umphumela wokuzola ebuchosheni nasezinzwa. Izakhiwo ze-anticonvulsant ze-Lorazepam zixhunywe ekubopheni kwayo eziteshini ze-sodium ezincike ku-voltage, ezikhawulela ukudubula okuphindaphindiwe okuqhubekayo. Kuyathakazelisa ukuthi indawo ebophayo ye-lorazepam inquma imiphumela yayo. Isibonelo, ukubopha ku-amygdala kusiza ngezinkinga zokukhathazeka, kuyilapho ukubopha izinsiza ze-cerebral cortex ekulawuleni ukuphazamiseka kokubanjwa.

Ngingakwazi Ukuthatha I-Diazepam Ngeminye Imithi?

Udinga ukuqapha lapho uthatha i-lorazepam neminye imithi. Kuyisibopho ukwazisa udokotela wakho ngayo yonke imithi eqhubekayo, ehlanganisa amakhambi, amavithamini, nezithako zokudla. I-Lorazepam ingaxhumana nezidakamizwa ezahlukahlukene, njenge: 

• Utshwala
• Izinhlungu ze-opioid noma ezinciphisa ukukhwehlela, njenge-codeine ne-hydrocodone
• antidepressant
• Imithi ye-Antiseizure njenge i-valproic acid
• Ama-Antihistamine afanayo cetirizine
• Ama-Antipsychotics afana ne-clozapine
• Ama-barbiturates afana ne-phenobarbital, pentobarbital, primidone
• insangu
• Ama-sedative kanye nezidakamizwa zokulala njenge-ketamine, i-zolpidem, i-zaleplon
• Amaphilisi ezinhlungu anamandla
• Imithi ye-herbal yokukhathazeka noma ukuqwasha njenge-valerian noma i-passionflower
• Iziphumuli zemisipha njenge-carisoprodol

Ulwazi Lomthamo

Abantu ngabanye bangathatha amaphilisi e-lorazepam ngokudla noma ngaphandle kokudla, ngokuvamile kabili noma kathathu ngosuku. 

Ngokukhathazeka kubantu abadala, odokotela ngokuvamile baqala ngo-2 kuya ku-3 mg nsuku zonke, bahlukaniswe ngemithamo. 

Ukubhekana nezinkinga zokulala, odokotela ngokuvamile baqala ngo-1 kuya ku-2 mg ngaphambi kokulala. 

Abantu abadala asebekhulile noma abantu abanezinkinga zezinso noma zesibindi bangadinga umthamo ophansi. 

Kubalulekile ukulandela imiyalelo kadokotela wakho kahle. Ukwelashwa kuvame ukuthatha isikhathi esifushane, ngokuvamile kufika amasonto amane. Udokotela wakho angase anciphise kancane kancane umthamo wakho ekupheleni kokwelashwa ukuze avimbele izimpawu zokuhoxa.

Isiphetho

I-Lorazepam inethonya ezimpilweni zethu ngezindlela eziningi, inikeza impumuzo ekukhathazekeni nasekuqwaleni kuyilapho idinga ukucatshangelwa ngokucophelela kokusetshenziswa kwayo. Ikhono lalo muthi lokuthulisa isimiso sezinzwa linikeza ukwesekwa okudingeka kakhulu kulabo abanenkinga yokukhathazeka, ukushaywa uvalo, nokuqwasha. Kodwa-ke, kubalulekile ukukhumbula ukuthi i-lorazepam iyisidakamizwa esinamandla esinemiphumela emibi engaba khona kanye nezingozi, okuhlanganisa ukozela, isiyezi, kanye nethuba lokuthembela.

Ukuze usebenzise i-lorazepam ngokuphepha, landela imiyalelo kadokotela wakho eduze futhi uqaphele noma yikuphi ukusebenzisana neminye imithi noma izinto. Nakuba i-lorazepam ingaba ithuluzi elibalulekile ekulawuleni ukukhathazeka nezinkinga zokulala, iyingxenye eyodwa nje yendlela yokwelapha ephelele yempilo yengqondo. Ukuhlanganisa imithi nokwelashwa, izinguquko zokuphila, nokuxhumana okuvulekile nodokotela kungaholela emiphumeleni engcono kakhulu futhi kuthuthukise inhlalakahle jikelele.

Imibuzo Evame Ukubuzwa

1. Ingabe i-lorazepam ibangela ukukhuluphala?

I-Lorazepam ingathonya isisindo, ibangele kokubili ukuzuza nokulahlekelwa. Ukusebenzisa isikhathi esifushane kungase kuholele ekwehleni kwesifiso sokudla nokuncipha kwesisindo, kuyilapho ukusetshenziswa kwesikhathi eside kungase kubangele ukukhuluphala. Lokhu kungase kube ngenxa yemiphumela yokuthulisa yomuthi, engase yehlise umsebenzi womzimba futhi ibambezele umzimba.

2. Ingabe i-lorazepam ibangela ukucindezeleka?

I-Lorazepam ingase ibangele ukushintsha kwemizwelo, okungase kuholele ekucindezelekeni noma emicabangweni yokuzibulala. Uma abantu benomlando wokuphazamiseka kwemizwa, ukuthatha i-lorazepam kungase kwandise ubungozi bokubuya kwalezi zimo noma zibe zimbi kakhulu. Kuyadingeka ukwazisa udokotela wethu nganoma yiziphi izimo zempilo yengqondo ezivele zikhona ngaphambi kokuqala ukwelashwa kwe-lorazepam.

3. Ubani okungafanele athathe i-lorazepam?

Uma kunomlando wokusebenzisa kabi izidakamizwa noma utshwala, isifo esinzima sokuphefumula, noma usengozini enkulu yokuwa, kunconywa ukugwema i-lorazepam. Akunconyelwe futhi kwabesifazane abakhulelwe noma abancelisa ibele, abantu abanokukhubazeka kwezinso noma kwesibindi, noma labo abanokucindezeleka okwase kuvele ukhona. Abantu abadala kanye nezingane bangase bazwele kakhulu emiphumeleni yako futhi kufanele bayisebenzise ngokuqapha.

4. Ingabe KULUNGILE ukuthatha i-lorazepam nsuku zonke?

Odokotela bavame ukunikeza i-lorazepam ukuthi isetshenziswe isikhathi esifushane, ngokuvamile kusukela ezinsukwini ezimbalwa kuya kumaviki angu-4. Ukuyithatha nsuku zonke isikhathi eside kungaholela emazingeni okuxhomekeka kanye nokuhoxa. 

5. Yikuphi okungcono, i-lorazepam noma i-clonazepam?

Kokubili i-lorazepam ne-clonazepam yi-benzodiazepines esetshenziselwa ukwelapha ukuphazamiseka kokukhathazeka. I-Lorazepam isetshenziselwa ukuqwasha nokuhoxiswa kotshwala, kuyilapho i-clonazepam isetshenziselwa ukuphazamiseka kokuthunjwa. Ukukhetha phakathi kwakho kokubili kuncike esimweni sethu esithile kanye nempendulo yomuntu ngamunye. 

6. Isebenza ngokushesha kangakanani i-lorazepam?

Ukuqala kwesenzo se-Lorazepam kuyahlukahluka futhi kuncike emzileni wokuphatha. Uma ithathwa ngomlomo, ngokuvamile iqala ukusebenza phakathi kwemizuzu engama-20 kuya kwengama-30. Kodwa-ke, lapho iphathwa ngomthambo, i-lorazepam iqala ukukhombisa imiphumela yomtholampilo ngemuva kwemizuzu emi-5, nomphumela wayo omkhulu ubonwa cishe imizuzu engama-20 ngemuva kokuphathwa.

7. Kwenzekani uma ngiphuthelwa umthamo?

Uma ukhohlwa ukuthatha umthamo wakho we-lorazepam ngokukhathazeka futhi kungaphansi kwamahora angu-3 kusukela kumthamo ogejiwe, kufanele uwuthathe ngokushesha nje lapho ukhumbula. Uma sekudlule amahora angaphezu kwama-3, kufanele weqe umthamo futhi uthole umthamo wakho olandelayo ngesikhathi esijwayelekile. Ngezinkinga zokulala, kufanele ushiye umthamo ogejiwe uma usadinga ukuwuthatha ngaphambi kokulala.

8. Yini okufanele ngiyigweme ngenkathi ngithatha i-lorazepam?

Abantu kufanele bagweme utshwala ngenkathi bethatha i-lorazepam, njengoba kungandisa amathuba okuba nemiphumela engemihle njengokulala nokucindezeleka kokuphefumula. Kubalulekile futhi ukugwema ukushayela imoto noma ukusebenzisa imishini uze wazi ukuthi i-lorazepam ikuthinta kanjani. Abantu akufanele bathathe noma yimiphi eminye imithi, kuhlanganise nezidakamizwa ezingekho emthethweni, ngaphandle kokubonisana nodokotela wabo kuqala ukuze baqinisekise ukuhambisana ne-lorazepam.