I-Meclizine

I-Meclizine

Wake wazizwa isiyezi noma isicanucanu ngesikhathi sokugibela imoto noma uhambo ngesikebhe? I-Meclizine ingaba yisixazululo osifunayo. Lo muthi uthole ukuduma ngokusebenza kwawo kulabo abanenkinga yebhalansi, ukungakhululeki kokuhamba, noma izimo ezithile zezokwelapha.

Le bhulogi ihlola ukusetshenziswa okuhlukahlukene kwe-meclizine, indlela yokuyisebenzisa kahle, imiphumela yayo engemihle engaba khona, kanye nezinyathelo zokuphepha ezidingekayo okufanele uzithathe.

Iyini i-Meclizine?

I-Meclizine umuthi ogunyazwe yi-FDA ongokwesigaba sama-antihistamine esizukulwane sokuqala. Ithole ukuduma ngokusebenza kwayo ekwelapheni ukugula kokunyakaza kanye ne-vertigo. Lo muthi usebenza njengomphikisi we-H1 ongakhethi, okusho ukuthi uvimba ama-receptors athile emzimbeni ukuze unciphise izimpawu ezihlobene nalezi zimo.

Ukusetshenziswa kwe-Meclizine

Amaphilisi e-Meclizine anohlu lwezinhlelo zokusebenza zokulawula izimo zezempilo ezahlukahlukene. Lokhu okulandelayo kukhona ukusetshenziswa kwe-meclizine:

• Ukulawulwa Kokugula Okunyakazayo: I-Meclizine isiza ukuvimbela nokwelapha isicanucanu, ukuhlanza, nesiyezi esibangelwa ukugula kokunyakaza. Ukuvimbela ukugula kokunyakaza, abantu kufanele bathathe umthamo wokuqala ihora elilodwa ngaphambi kokuqala imisebenzi efana nokuhamba. 
• Ukwelashwa kwe-Vertigo: I-Meclizine inciphisa isiyezi nokulahlekelwa ibhalansi (i-vertigo) ebangelwa izinkinga zendlebe yangaphakathi, kuhlanganise nezifo ze-vestibular ezifana nesifo sikaMeniere kanye ne-benign paroxysmal positional vertigo (BPPV).

Okunye Ukusetshenziswa: Odokotela bangase banikeze amaphilisi e-meclizine ukuze asetshenziswe kaningi ngaphandle kwelebula:

• Izifo ezibangelwa amagciwane
• Izifo ezithinta esiswini
• Isicanucanu esihlobene nokukhulelwa
• Isicanucanu esidalwa yi-radiation therapy
• Ukuhlaselwa okunamandla kwe-vestibular migraine

Ungayisebenzisa kanjani iMeclizine

I-Meclizine itholakala ngezindlela ezihlukahlukene, okuhlanganisa amaphilisi avamile, amaphilisi ahlafunwayo, namaphilisi. Ukusetshenziswa kahle kwalo muthi kuncike esimweni sokwelashwa kanye nemiyalelo kadokotela eqondile.

• Ukuvimbela ukugula okunyakazayo, abantu kufanele bathathe i-meclizine ihora elilodwa ngaphambi kokuqala uhambo lwabo. Uma kunesidingo, imithamo eyengeziwe ingathathwa njalo emahoreni angama-24 phakathi nohambo.
• Uma usebenzisa amaphilisi ahlafunwayo, iziguli zingawahlafuna kahle noma ziwagwinye ephelele. 
• I-Meclizine ingathathwa ngokudla noma ngaphandle kwayo.
• Uma uphuthelwe umthamo, thatha ngokushesha ngangokunokwenzeka. Kodwa-ke, uma sekusondele isikhathi sethamo elilandelayo, yeqa leyo eseyivele igejiwe futhi uqalise kabusha uhlelo olujwayelekile lokudosa. Kubalulekile ukuthi ungaphindi imithamo.

Imiphumela Emibi Yethebhulethi ye-Meclizine

Imiphumela engemihle ye-meclizine isukela kokujwayelekile nokuthambile kuye kokuqina futhi okungajwayelekile, okuhlanganisa:

Imiphumela Emibi Evamile:

• Ukulala
• Ukukhathala
• bekhanda
• Umbono ophundlekile
• Umlomo omile

Imiphumela Emibi Ebi: Nakuba ingavamile, abanye abantu bangase babe nemiphumela engathi sína edinga ukunakwa ngokushesha. Lokhu kubandakanya:

• Ukungezwani Nomzimba: Izimpawu zingase zihlanganise ukuphefumula kanzima, ukuvuvukala komphimbo noma ulimi, ukuqubuka, ukulunywa, noma isiyezi esinzima.Izinguquko Zengqondo/Zomumo: Lokhu kungase kubonakale njengokungahlaliseki noma ukudideka.
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ukuthuthumela
• Kunzima ukuchama
• Ukuquleka (okungavamile)

Ukusebenzisana kwezidakamizwa

I-Meclizine ingasebenzisana neminye imithi, okungase kwandise ingozi yemiphumela engemihle. Lokhu kubandakanya:

• Imithi yokulwa nokukhathazeka
• Imithi yokungezwani komzimba
• Izidakamizwa zokuphazamiseka kwengqondo
• Imithi yokuqwasha
• Ama-relaxant muscle

Ukuthatha i-meclizine ngale mithi kungandisa ingozi yemiphumela yokudambisa, okuhlanganisa ukozela, ukuphefumula kancane, nokukhubazeka kwengqondo.

Ukuqapha

Nakuba iphumelela ekwelapheni ukugula kokunyakaza kanye ne-vertigo, i-meclizine idinga ukucatshangelwa ngokucophelela ngaphambi kokusetshenziswa. Iziguli kufanele zazise udokotela wazo mayelana nokungezwani komzimba nezinto ezithile, njengoba lo muthi ungase ube nezithako ezingasebenzi ezingase zibangele ukungezwani komzimba noma ezinye izinkinga.

• I-Meclizine ithinta ukuqapha futhi ingabangela ukozela. Abasebenzisi kufanele bagweme ukushayela, ukusebenzisa imishini, noma ukuzibandakanya emisebenzini edinga ukuqapha kuze kube yilapho udokotela wabo ebatshela.
• Izingane ezingaphansi kweminyaka engu-12 ubudala
• Abesifazane abakhulelwe nomama abancelisa ibele
• Abantu abadala asebekhulile bangase bangenwe kalula yimiphumela, ikakhulukazi ukozela, ukudideka, noma izinkinga zomchamo. 
•  Abantu abanomlando wokungezwani ne-meclizine noma izithako zayo
•  Abantu abaphuza imithi ethile: I-Meclizine ingaxhumana nemithi ehlukahlukene, kuhlanganise:
  •  Imithi yokulwa nokukhathazeka
  •  Izidakamizwa zokuphazamiseka kwengqondo
  •  Ama-relaxant muscle
  •  Amanye ama-antihistamines
  •  Imithi yokulala
•  Abantu abanomlando othile wezokwelapha, okuhlanganisa:
  •  Izinkinga zokuphefumula (isifuba somoya, i-emphysema)
  •  I-glaucoma
  •  Izinkinga zenhliziyo
  •  Umfutho wegazi ophezulu
  •  ukuquleka
  •  Izifo zesisu (njengezilonda noma ukuvinjelwa)
  •  I-thyroid engasebenzi ngokweqile (hyperthyroidism)
  •  Ubunzima bokuchama (isb, ngenxa yokwanda kwe-prostate)
  •  Izinkinga zesibindi
  •  Izinkinga zezinso

Isebenza kanjani iMeclizine

I-Meclizine, i-antihistamine yesizukulwane sokuqala, ithinta kakhulu umzimba ngezenzo zayo ezimaphakathi ze-anticholinergic. Lezi zenzo zinikeza i-meclizine izakhiwo zayo ze-antiemetic (anti-nausea) kanye ne-antivertigo. Umuthi usebenza ngokuvimbela ama-histamine H1 receptors futhi unezenzo ezimaphakathi ze-anticholinergic. Le miphumela yokuvimba ivela ezindaweni ezithile zobuchopho, okuhlanganisa:

• Isikhungo sokuhlanza ku-medulla
• I-chemoreceptor trigger zone (CTZ)
• I-nucleus yepheshana elizimele (NTS)
• I-vestibular nuclei

Ngokuvimbela amasiginali nge-histamine neurotransmission kulezi zindawo, i-meclizine yehlisa ukugqugquzelwa kwe-vestibular kanye nokuthakasela kwe-labyrinth. Lesi senzo sinciphisa ngempumelelo izimpawu zokugula kokunyakaza kanye ne-vertigo.

Ngingakwazi Ukuthatha I-Meclizine Neminye Imithi?

Imithi eminingi isebenzisana ne-meclizine, yingakho iziguli kufanele ziqaphele lapho ziyiphuza neminye imithi. Ezinye izidakamizwa ezijwayelekile ezisebenzisana nemithi ye-meclizine zifaka:

• Izinsiza zokulala ezitholakala ngaphandle kwekhawunta eziqukethe ama-antihistamine esizukulwane sokuqala njenge-diphenhydramine noma i-doxylamine zingaqinisa imiphumela engemihle efana nokozela, isiyezi, nomlomo owomile uma kuhlanganiswa ne-meclizine.
• Imithi ye-Anticholinergic ingaba yimbi kakhulu imiphumela emibi eyabiwe nge-meclizine, kuhlanganise ukuqunjelwa, ukubona lufifi, nokudideka.
• I-Benzodiazepines ingase yandise imiphumela emibi okwabelwana ngayo nge-meclizine, okuhlanganisa ukozela, ikhanda elibuhlungu, nokuhlanza. Ezimweni ezimbi kakhulu, le nhlanganisela ingaholela ekuphefumuleni okunensayo okuyingozi.
• I-Dronabinol, esetshenziselwa ukwelapha isicanucanu nokuhlanza ngenxa yokwelashwa ngamakhemikhali, kufanele igwenywe nge-meclizine ngoba ingaholela ekusebenzeni kwengqondo okubi, ukozela, kanye nezinguquko zomfutho wegazi noma ukushaya kwenhliziyo.
• Ama-antihistamine esizukulwane sokuqala angabangela ukozela ngokweqile kanye nemiphumela engemihle eyabiwe ibe mibi kakhulu lapho ehlanganiswa ne-meclizine. 
• Ama-opioid angabangela ukozela nokuphefumula kancane lapho ethathwa ne-meclizine.
• I-Phenobarbital ingaqinisa ukozela kanye nokuphefumula okungaba yingozi okungaba yingozi uma kuhlanganiswe ne-meclizine.
• Ukuhlanganisa utshwala ne-meclizine akunconywa, ngoba zombili izinto zibangela ukozela kanye nokusebenza kancane kobuchopho.

Ulwazi Lomthamo

Umthamo womuthi we-Meclizine uyahlukahluka kuye ngeminyaka yesiguli, isimo, nezidingo. Odokotela bahlela isilinganiso ukuze sivumelane nomuntu ngamunye, becabangela izici ezinjengobunzima bezimpawu nendlela isiguli esisabela ngayo ekwelashweni.

Iziguli kufanele zilandele ngokucophelela imiyalelo kadokotela noma iziqondiso ezikulebula.

• Isifo Sokunyakaza (Abadala):
  • Umthamo wokuqala: 25 kuya ku-50 milligrams ngomlomo, ihora eli-1 ngaphambi kohambo
  • Umthamo wesondlo: Phinda njalo emahoreni angama-24 uma kudingeka
• I-Vertigo (Abadala):
  • 25 kuya ku-100 mg ngomlomo ngosuku, ihlukaniswe ngemithamo eminingi
  • Umthamo ulungisiwe ngokusekelwe ekuphenduleni komtholampilo
• Izingane (iminyaka engu-12 nangaphezulu):
  • Udokotela kufanele anqume umthamo wakho kokubili ukugula kokunyakaza kanye ne-vertigo
• Izingane (ezingaphansi kweminyaka engu-12):
  • Akunconyelwe

Isiphetho

I-Meclizine umuthi oguquguqukayo onezinhlobonhlobo zezinhlelo zokusebenza. Kusukela ekusetshenzisweni kwethebhulethi ye-meclizine ekwelapheni ukugula okunyakazayo kanye ne-vertigo kuya emandleni ayo ekulawuleni izimpawu zokuhoxa kanye nokusetshenziswa okungenzeka esikhathini esizayo ekwelapheni i-achondroplasia, i-meclizine ibonisa ukuguquguquka okuphawulekayo. Njenganoma yimuphi umuthi, kubalulekile ukubonana nodokotela ngaphambi kokusebenzisa i-meclizine ukuze uqinisekise umthamo ofanele futhi unciphise izingozi ezingaba khona kuyilapho wandisa izinzuzo zayo.

FAQ sika

1. Isetshenziselwa ini isidakamizwa i-meclizine?

I-Meclizine isiza ukuphatha izimo ezahlukahlukene ezihlobene nokulinganisela nesicanucanu. Odokotela banikeza le mithi ngokuyinhloko ngenxa yesifo sokunyakaza, i-vertigo, nesicanucanu kanye oluhlanzayo.

2. Ngingakwazi yini ukuthatha i-meclizine nsuku zonke?

Nakuba i-meclizine ingasebenza ngempumelelo ekulawuleni izimpawu ze-vertigo nesifo sokunyakaza, ngokuvamile ayinconyelwe ukusetshenziswa isikhathi eside nsuku zonke ngaphandle kokugadwa udokotela. Ukusetshenziswa njalo kwe-meclizine kungase kuphazamise izindlela zokunxephezela zesimiso sezinzwa esimaphakathi, okungase kuholele ekwehleni noma ekungapheleleni kokululama ku-vertigo. Ukulandela umthamo onqunyiwe kanye nokubonana nodokotela ngaphambi kokusebenzisa i-meclizine isikhathi eside kubalulekile.

3. Ingabe i-meclizine iyingozi ezinso zakho?

Umthelela we-meclizine ekusebenzeni kwezinso awukahlolisiswa kabanzi futhi iphrofayili yayo yokuphepha kubantu abanezinkinga zezinso ihlala ingaqiniseki. Ngenxa yokunqwabelana okungenzeka komuthi ohlelweni lwabo, abantu abanezinkinga zezinso bangase babe lula ukuthola imiphumela engemihle. Iziguli ezinezinkinga zezinso kufanele zixoxe ngokusetshenziswa kwe-meclizine nodokotela wazo ngaphambi kokuqala ukwelashwa.

4. Ubani ongakwazi ukuthatha i-meclizine?

Amaqembu amaningana abantu kufanele aqaphele noma agweme ukuthatha i-meclizine ngokuphelele. Odokotela ngokuvamile abayincomi i-meclizine kulokhu:

• Abantu abadala kanye nezingane ezingaphansi kweminyaka engu-12
• Abantu abanezimo ezithile zezempilo, njengezifo zokuphefumula, i-glaucoma, i-prostate ekhulisiwe, izinkinga zesibindi, kanye nesifo sokuwa.
• Abesifazane abakhulelwe nomama abancelisa ibele
• Abantu baphuza imithi ethile, njengemithi yokulala, imithi yokulwa nokukhathazeka, ama-antihistamine, noma iziphumuza imisipha.
• Abantu abanomlando wokungezwani ne-meclizine noma izithako zayo
• Abantu abanomlando othile wezokwelapha, njengezinkinga zenhliziyo, umfutho wegazi ophakeme, izinkinga zesisu (njengezilonda noma ukuvaleka), noma i-hyperthyroidism.