UMeloxicam

UMeloxicam

I-Meloxicam noma i-Moxicam iyisidakamizwa esingeyona i-steroidal anti-inflammatory (NSAID) esetshenziselwa ukukhulula izinhlobo ezahlukene zobuhlungu nokuvuvukala. Ingokwesigaba semithi ebizwa ngokuthi ama-NSAID, asebenza ngokumisa ukukhiqizwa kwezinto ezibangela ubuhlungu, imfiva, nokuvuvukala.

Ukusetshenziswa kweMeloxicam

Amaphilisi e-Meloxicam asetshenziselwa ukuphatha ubuhlungu, ukuvuvukala, nokuqina okuhambisana nezimo ezihlukahlukene. Ukusetshenziswa kwayo okuyinhloko kuhlanganisa:

• I-Osteoarthritis: I-Meloxicam isiza ukunciphisa ubuhlungu, ukuzwela, ukuvuvukala, nokuqina kwamalunga athintekile.
• I-Rheumatoid Arthritis: I-Meloxicam ivunyelwe ukwelapha ubuhlungu obuhlangene, ukuvuvukala, nokuqina okubangelwa i-rheumatoid arthritis, ukuphazamiseka kwe-autoimmune okuholela ekuvuvukeni kwamalunga okungapheli.
• I-Juvenile Idiopathic Arthritis (JIA): Amaphilisi e-Moxicam angasetshenziswa ukuphatha izimpawu ze-Juvenile Idiopathic Arthritis (JIA), ebizwa nangokuthi i-Juvenile Rheumatoid Arthritis, ezinganeni ezineminyaka emibili nangaphezulu. Lesi simo sibangela ubuhlungu bamalunga, ukuvuvukala, nokuqina kwezingane.
• Okunye Ukusetshenziswa: Nakuba ingagunyaziwe kule mibandela, i-meloxicam ngezinye izikhathi inqunywa ngaphandle kwelebula:
  • I-ankylosing spondylitis
  • Ubuhlungu bamazinyo noma ngemva kokuhlinzwa
  • Ezinye izifundo ziphakamisa ukuthi i-meloxicam ingasiza ekudambiseni izinhlobo ezithile zobuhlungu obuhlobene nezinzwa.

Ungayisebenzisa kanjani iMeloxicam

• Imiyalelo Yesilinganiso
  • Thatha i-meloxicam ngokunembile njengoba udokotela wakho ekutshela, futhi ungeqi umthamo onconywayo noma uyiphuze kaningi kunalokho okushiwo. Ukuthatha i-meloxicam eningi kungandisa ingozi yemiphumela emibi.
• Imihlahlandlela yokuphatha:
  • Geza amaphilisi noma amaphilisi wonke ngengilazi yamanzi. Ungawachobozi, uwaphule, noma uwahlafune.
  • Ungathatha i-meloxicam ngokudla noma ngaphandle kokudla.
  • Ukuze uthole amaphilisi ahlakazekayo ngomlomo, khipha ithebhulethi ephaketheni lamabhamuza ngaphambi nje kokuyithatha. Yibeke olimini lwakho futhi uyivumele ukuba incibilike ngaphambi kokugwinya, noma ngaphandle kwamanzi.
  • Nyakazisa uketshezi lomlomo kahle ngaphambi kokusetshenziswa ngakunye bese ukala umthamo ngokunembile usebenzisa umshini wokulinganisa omakiwe.

Imiphumela Emibi Yethebhulethi ye-Meloxicam

Njengeminye imithi, i-meloxicam ingabangela imiphumela ethile engemihle, kusukela emincane ukuya kwemibi kakhulu. 

• Imiphumela Emibi Evamile: Imiphumela evame kakhulu ehlobene ne-meloxicam ihlanganisa:
  • Ubuhlungu besisu
  • Uhudo
  • Ukuqunjelwa noma isilungulela
  • I-nausea
  • isiyezi
  • bekhanda
  • Ukuluma noma ukuqubuka
• Imiphumela Emibi Kakhulu: Funa usizo lwezokwelapha ngokushesha uma uba nanoma yimiphi imiphumela emibi elandelayo:
  • Isifo senhliziyo
  • Stroke
  • Izinkinga zesisu namathumbu
  • Ukulimala kwesibindi
  • Ukwanda kwengcindezi yegazi
  • Ukugcinwa kwamanzi noma ukuvuvukala
  • Izinkinga Zesikhumba
  • Ukulimala Kwezinso
  • Imiphumela emibi yesisu njengobuhlungu besisu, isifo sohudo, ukungagayeki kahle, kanye nesicanucanu. 

Ukuqapha

Ngaphambi kokuthatha i-meloxicam, kufanele uqaphele izinyathelo ezimbalwa ezibalulekile zokuqinisekisa ukuphepha kwakho futhi unciphise ubungozi bemiphumela emibi.

• I-Alergic Reactions: Yazisa udokotela wakho mayelana nokungezwani komzimba ne-meloxicam, i-aspirin, noma ezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID). I-Meloxicam ingase ibangele ukungezwani okunzima, okusongela ukuphila okubizwa ngokuthi i-anaphylaxis, okuhlanganisa ukuphefumula okusheshayo noma okungajwayelekile, ukuhefuzela, ukuquleka, ukuvuvukala kobuso, amajwabu amehlo, noma umphimbo, kanye nesifuba.
• Izingozi zenhliziyo nemithambo yegazi: I-Meloxicam ingandisa ingozi yokuhlaselwa yinhliziyo, amahlule egazi, noma unhlangothi, ikakhulukazi uma usuvele unesifo senhliziyo noma semithambo yegazi noma uyisebenzisa isikhathi eside. 
• Izingozi Zamathumbu: I-Meloxicam ingabangela ukopha kwesisu noma emathunjini, izilonda, noma izinyembezi, ngisho nangaphandle kwezimpawu eziyisixwayiso. 
• Izinkinga Zesibindi Nezinso: I-Meloxicam ingase ibangele izinkinga zesibindi noma zezinso, ikakhulukazi ngokusetshenziswa isikhathi eside. Bheka izimpawu ezinjengobuhlungu besisu, isicanucanu, ukuhlanza, i-anorexia (ukuphelelwa ukudla), ukuguga okuphuzi kwesikhumba noma amehlo, umchamo onombala omnyama, indle enobumba, ukuvuvukala, noma ukuncipha kokuchama. 
• Ukukhulelwa: Ukusebenzisa i-meloxicam phakathi nezigaba zakamuva zokukhulelwa kungalimaza ingane engakazalwa. Akwaziwa uma i-meloxicam idlula obisini lwebele, ngakho-ke thintana nodokotela wakho ngaphambi kokuncelisa.
• Ukukhathazeka Ngenzalo: I-Meloxicam ingabangela ukubambezeleka kwe-ovulation kwabesifazane futhi yehlise inani lesidoda emadodeni, okungase kuthinte inzalo. 
• Ezinye Izinyathelo Zokuqapha:
  • Gwema utshwala nogwayi ngenkathi uthatha i-meloxicam, njengoba kungandisa amathuba okuphuma kwegazi esiswini.
  • I-Meloxicam ingadala isiyezi, ngakho gwema ukushayela noma ukusebenzisa imishini.
  • Nciphisa ukuchayeka elangeni futhi usebenzise i-sunscreen, njengoba i-meloxicam ingase ikhulise ukuzwela kwakho ukukhanya kwelanga.
  • Abantu abadala asebekhulile basengozini yokuba nemiphumela engemihle, njengezinkinga zezinso, ukopha esiswini, isifo senhliziyo, nesifo sohlangothi.

Isebenza kanjani iMeloxicam?

I-Meloxicam iyimithi elwa nokuvuvukala, i-analgesic (edambisa izinhlungu), kanye ne-antipyretic (eyehlisa umkhuhlane). I-Meloxicam ivimbela ama-enzyme i-cyclooxygenase-1 (COX-1) kanye ne-cyclooxygenase-2 (COX-2), ebalulekile ekuhlanganiseni kwe-prostaglandin, ebangela ukuvuvukala, ubuhlungu nokushisa komzimba.

Ngokuvimbela ngokukhethekile i-COX-2 ngaphezu kwe-COX-1, i-meloxicam inciphisa ukukhiqizwa kwe-prostaglandin ehilelekile ekuvuvukeni, ebuhlungu nasemfivani kuyilapho ingabangela ukucasuka okuncane kwesisu kunama-NSAID angakhethi.

Ngingakwazi Ukuthatha I-Meloxicam Neminye Imithi?

Ezinye izidakamizwa zingase zihlanganyele ne-meloxicam futhi zandise ubungozi bemiphumela emibi noma zehlise ukusebenza kwayo, okubandakanya:

• I-Blood Thinners (Anticoagulants): I-Meloxicam ingase inyuse ingozi yokopha uma ithathwa nezinto ezinciphisa igazi.
• I-Aspirin namanye ama-NSAID: Gwema ukuthatha i-meloxicam nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) noma i-aspirin, njengoba lokhu kungandisa amathuba okuba nezilonda zesisu nokopha.
• I-Corticosteroids: I-Meloxicam ingase inyuse ingozi yemiphumela emibi yesisu uma ithathwa ne-corticosteroids.
• I-Diuretics (Amaphilisi Amanzi): I-Meloxicam inganciphisa ukusebenza kwe-diuretics, okuholela ekugcinweni koketshezi kanye nomfutho wegazi owandayo.
• I-ACE Inhibitors nama-ARB: I-Meloxicam ingase yehlise umphumela wokwehlisa umfutho wegazi wama-angiotensin-converting enzyme (ACE) inhibitors nama-angiotensin II receptor blockers (ARBs) asetshenziselwa ukwelapha umfutho wegazi ophakeme noma ukwehluleka kwenhliziyo.
• I-Methotrexate: I-Meloxicam ingase ikhulise amazinga e-methotrexate, okuholela ekwandeni kwemiphumela emibi.
• I-Lithium: I-Meloxicam ingase ikhulise amazinga e-lithium, imithi esetshenziselwa ukwelapha ukuphazamiseka kwe-bipolar, okungase kubangele ubuthi be-lithium.
• I-Cyclosporine: I-Meloxicam ingase ikhulise amazinga e-cyclosporine (umuthi osetshenziselwa ukuvimbela ukwenqatshwa kokufakelwa kwesitho), okuholela ekwandeni kwemiphumela emibi.
• Ama-Antidepressants (SSRIs kanye nama-SNRIs): I-Meloxicam ingase ikhulise ingozi yokopha uma ithathwa ne-Serotonin Nor-epinephrine Reuptake Inhibitors (SNRIs) noma i-Selective Serotonin Reuptake Inhibitors (SSRIs). Lezi zisetshenziselwa ukwelapha ukucindezeleka nokukhathazeka.
• Izithako Zemithi: Izithako ezithile zemithi, njenge-ginkgo biloba, i-garlic, ne-ginger, zingandisa ingozi yokopha lapho zithathwa nge-meloxicam.

Ulwazi Lomthamo

Umthamo ofanele we-meloxicam uncike ezicini eziningana, njengesifo esiphathwayo, ubudala, isisindo, kanye nokusabela komuntu ngamunye emuthini. Nazi iziqondiso ezijwayelekile zokudosa:

Umthamo Ojwayelekile Wabantu Abadala

• I-Osteoarthritis: Amaphilisi Omlomo kanye namathebulethi Ahlukanisayo Omlomo:
  • Umthamo wokuqala: 7.5 mg othathwe ngomlomo kanye ngosuku
  • Umthamo wesondlo: 15 mg othathwe ngomlomo kanye ngosuku ezigulini ezidinga ukukhululeka okwengeziwe kobuhlungu
  • Umthamo omkhulu: 15 mg othathwe ngomlomo kanye ngosuku
• Amaphilisi omlomo:
  • Umthamo wokuqala: 5 mg othathwe ngomlomo kanye ngosuku
  • Umthamo wesondlo: 10 mg othathwe ngomlomo kanye ngosuku ezigulini ezidinga ukukhululeka okwengeziwe kobuhlungu
  • Umthamo omkhulu: 10 mg othathwe ngomlomo kanye ngosuku
• I-Rheumatoid Arthritis: Amaphilisi Omlomo kanye namathebulethi Ahlukanisayo Omlomo:
  • Umthamo wokuqala: 7.5 mg othathwe ngomlomo kanye ngosuku
  • Umthamo wesondlo: 15 mg othathwe ngomlomo kanye ngosuku ezigulini ezidinga ukukhululeka okwengeziwe kobuhlungu
  • Umthamo omkhulu: 15 mg othathwe ngomlomo kanye ngosuku
• Ubuhlungu Obunzima:
  • 30 mg intravenous (IV) bolus (ngaphezu kwemizuzwana eyi-15) kanye ngosuku
  • Umthamo Ojwayelekile Wezingane we-Juvenile Rheumatoid Arthritis:
• Iminyaka emibili noma ngaphezulu: Amaphilisi Omlomo kanye namathebulethi Ahlukanisayo Omlomo:
  • Isisindo: 60 kg noma ngaphezulu: 7.5 mg sithathwe ngomlomo kanye ngosuku
  • Amaphilisi omlomo akufanele asetshenziswe ezinganeni ezinesisindo esingaphansi kwama-60 kg.

Isiphetho

I-Meloxicam igqama njengethuluzi elinamandla ekulawuleni ubuhlungu nokuvuvukala, enikeza ukukhululeka ezimeni ezifana nesifo samathambo nezinye izifo ezivuthayo. Ikhono layo lokukhomba ama-enzyme e-COX-2 ngokukhetha kakhudlwana kune-COX-1 lenza inketho ebalulekile kulabo abafuna ukuphathwa kobuhlungu okuphumelelayo nemiphumela engemihle ye-gastrointestinal engase ibe mbalwa uma kuqhathaniswa namanye ama-NSAID. 

Ngokuhlala unolwazi mayelana nokusetshenziswa okufanele, imiphumela engemihle engaba khona, nezinyathelo zokuphepha ezidingekayo, ungakwazi ukusebenzisa izinzuzo ze-meloxicam kuyilapho unciphisa izingozi empilweni yakho.

Imibuzo Evame Ukubuzwa

1. Ingabe i-meloxicam isidambisi esihle sobuhlungu?

Yebo, i-meloxicam iyisidambisa-zinhlungu esisebenzayo. Iyingxenye ye-Non-steroidal Anti-inflammatory Drugs (NSAIDs) futhi yaziwa ngokuqeda ukuvuvukala, i-analgesic (edambisa izinhlungu), kanye ne-antipyretic (eyehlisa umkhuhlane). 

2. Ingabe i-meloxicam iyasiza ubuhlungu bezinzwa?

Nakuba i-meloxicam ngokuyinhloko isetshenziselwa ukwelapha ubuhlungu nokuvuvukala okuhambisana nezimo ezifana nesifo samathambo, ezinye izifundo zisikisela ukuthi zingase zibe usizo nobuhlungu be-neuropathic (ubuhlungu obuhlobene nemizwa).