I-Minocycline

I-Minocycline

I-Minocycline, i-antibiotic ebanzi, ibilokhu yenza amagagasi emhlabeni wezokwelapha. Siwubonile umthelela wawo ekwelapheni izifo ezihlukahlukene zamagciwane kanye namandla awo ekulawuleni izimo ezithile zesikhumba. Njengelungu lomndeni we-tetracycline, i-minocycline isiza ekwelapheni izifo eziningi ezithathelwanayo nezingezona ezithathelwanayo, okwenza kube inketho yodokotela abaningi.

Ake sihlole ukungena nokuphuma kwe-minocycline, okuhlanganisa ukusetshenziswa kwayo, umthamo, kanye nemiphumela engemihle engaba khona. Sizobheka ukuthi ungasebenzisa kanjani amaphilisi e-minocycline ngendlela efanele futhi sixoxe ngezinyathelo ezibalulekile okufanele uzikhumbule. Kungakhathaliseki ukuthi ucabangela i-minocycline 100 mg yezinduna noma ufuna ukwazi mayelana nezinhlelo zayo ezihlukene, sikumbozile.

Iyini i-Minocycline?

I-Minocycline iyi-antibiotic enamandla yomndeni we-tetracycline. Odokotela bayisebenzisela ukwelapha izifo ezibangelwa amagciwane ahlukahlukene, okuhlanganisa kodwa okungagcini nje kuphela kulabo abathinta umgudu wokuphefumula, isikhumba, nohlelo lomchamo. Isebenza kakhulu ngokumelene nama-bacteria e-gram-positive kanye ne-gram-negative. Amaphilisi e-Minocycline nawo avame ukunqunywa ukuphatha i-acne enzima.

Ukusetshenziswa kwethebhulethi ye-Minocycline

Okulandelayo ukusetshenziswa okujwayelekile kwe-minocycline:

• Lesi sibulala-magciwane esisebenza ngezindlela eziningi sisebenza kahle ngokumelene nenyumoniya nezinye izifo zemigudu yokuphefumula. 
• Odokotela baphinde banikeze i-minocycline yesikhumba esithile, iso, i-lymphatic, amathumbu, isitho sangasese, kanye izifo zomchamo. 
• Amaphilisi e-Minocycline asiza ekwelapheni izifo ezisakazwa imikhaza, izintwala, izibungu, nezilwane ezinamagciwane.
• Ngaphandle kwezakhiwo zayo zokulwa namagciwane, odokotela bavame ukusebenzisa i-minocycline 100 mg kanye neminye imithi yokuphatha induna enzima. Isebenza kahle kakhulu ekubulaleni amabhaktheriya angena ezimbotsheni kanye nokunciphisa izinto ezinamafutha abangela ukuqubuka.
• Amaphilisi e-Minocycline anezinye izinto ezibalulekile ezisetshenziswayo futhi. Abanye odokotela bangase babanikeze ukwelapha isifo esiwumshayabhuqe kanye ne-tularemia, izifo ezinzima ezingasetshenziswa ekuhlaselweni kwe-bioterror. 
• Ezigulini ezingakwazi ukuthatha i-penicillin, i-minocycline ingenye indlela yokwelapha izinhlobo ezithile zobuthi bokudla kanye ne-anthrax.

Indlela Yokusebenzisa Ithebhulethi ye-Minocycline

• Ungeqi umthamo onconyiwe we-minocycline noma ubude besikhathi ukuze ugweme imiphumela emibi engaba khona. 
• Ngaso sonke isikhathi gwinya ithebhulethi lonke ngengilazi yamanzi egcwele esiswini esingenalutho noma ihora elingu-1 ngaphambi noma amahora angu-2 ngemva kokudla. Nokho, ukuyithatha kanye nokudla kungase kuthinte ukusebenza kwayo, ngakho thintana nodokotela wakho.
• Qiniseka ukuthi uhlukanisa imithamo ngokulinganayo, njalo emahoreni ayi-12, futhi uqhubeke nayo yonke inkambo yokwelashwa ngisho noma izimpawu ziba ngcono. 
• Kubalulekile ukuthi ungalali okungenani imizuzu eyi-10 ngemuva kokuthatha amaphilisi e-minocycline. Futhi, gwema ukuwathatha ngaphambi nje kokulala.
• Ukuze uqinisekise ukumuncwa okufanele, thatha amaphilisi e-minocycline amahora angu-2 kuya kwangu-3 ngaphambi noma ngemva kwezinto eziqukethe i-aluminium, i-calcium, insimbi, i-magnesium, noma i-zinc.

Imiphumela Emibi Yethebhulethi ye-Minocycline

Amaphilisi e-Minocycline angabangela imiphumela ethile engadingeki kanye nezinzuzo ezihlosiwe. Imiphumela emibi evamile ihlanganisa: 

• I-nausea
• Ukuvota
• Uhudo
• isiyezi 

Imiphumela emibi kakhulu, nakuba ingavamile, yilezi: 

• Izinkinga zezinso, njengomchamo opinki noma ukwehla kokuphuma komchamo
• Izinkinga zesibindi, njengobuhlungu besisu, umchamo onombala omnyama, noma ukuphuzi kwesikhumba noma amehlo 
• Izinkinga zokuzwa, njengokungezwa kahle noma ukukhala ezindlebeni
• Ukushintsha umbala kwamazinyo, ikakhulukazi ezinganeni
• Isikhumba hyperpigmentation
• ubuhlungu Joint kanye nokuqina
• Kwezinye izimo, kungase kwandise ingcindezi ezungeze ubuchopho, okuholela ekhanda elibuhlungu noma izinguquko zombono. 
• I-Minocycline ayikwazi ukubangela isimo esinzima samathumbu ngenxa ye-C. difficile bacteria. Uma uthola isifo sohudo esingapheli noma ubuhlungu besisu, funa usizo lwezokwelapha ngokushesha. 

Kubalulekile ukukhumbula ukuthi nakuba le miphumela engemihle ingenzeka, abantu abaningi basebenzisa i-minocycline ngaphandle kokuba nezinkinga ezinkulu.

Ukuqapha

• Umlando Wezidakamizwa: Kubalulekile ukwazisa udokotela wakho mayelana nokungezwani komzimba nezinto ezithile, ikakhulukazi ama-antibiotic e-tetracycline. I-Minocycline inganciphisa amandla amaphilisi okulawula ukuzalwa, ngakho sebenzisa izindlela zokuvimbela inzalo ezengeziwe. 
• Ukukhulelwa Nokuncelisa: Okhulelwe noma abesifazane abancelisayo kufanele igweme i-minocycline njengoba ingalimaza ingane engakazalwa noma idlulele obisini lwebele. 
• Izingane: Unganikezi lo muthi ezinganeni ezingaphansi kweminyaka eyisishiyagalombili ngenxa yengozi yokushintsha kombala kwamazinyo. 
• Ukuzwela ku-Sunlight: I-Minocycline ingandisa ukuzwela kwesikhumba ekukhanyeni kwelanga, ngakho zivikele lapho ungaphandle. 
• Imigomo: I-Minocycline ingase yehlise ukusebenza komgomo webhaktheriya ophilayo. Ngakho-ke, yazisa udokotela wakho ngaphambi kokuthola noma yimiphi imigomo.

Ukuhlolwa njalo nodokotela kusiza ukuqapha ukusebenza komuthi kanye nanoma yimiphi imiphumela engadingeki.

Isebenza kanjani i-Minocycline Tablet

I-Minocycline, i-antibiotic yesizukulwane sesibili se-tetracycline, ithonya kokubili amagciwane e-gram-positive kanye ne-gram-negative. Ibophezela kubhaktheriya i-30S ribosomal subunit, imise ukwakheka kwamaprotheni. Le nqubo ivimbela i-aminoacyl-tRNA ekunamatheleni ku-ribosome, imise ukukhula kwebhaktheriya nokuphindaphinda.

Okuthakazelisayo ngamaphilisi e-minocycline imvelo yawo ye-lipophilic. Lokhu kusho ukuthi angakwazi ukweqa kalula ulwelwesi lwebhayoloji, okuholela ekumunceni nasekusabalaleni ngokushesha kuwo wonke umzimba. Eqinisweni, i-minocycline ine-lipophilicity enkulu kunamanye ama-tetracyclines, okuholela ekugxilweni okuphezulu ohlelweni lwezinzwa oluphakathi nesikhumba.

Ukumuncwa kwamaphilisi e-minocycline kwenzeka esiswini namathumbu amancane. Kodwa-ke, kufanele kuqashelwe ukuthi ukudla, ikakhulukazi izinto eziqukethe i-calcium, kungathinta amazinga okumuncwa. Lezi zakhi zingabopha nge-minocycline, okwenza kube nzima ukuthi umzimba ukwazi ukumunca.

Ngingakwazi Ukuthatha I-Minocycline Neminye Imithi?

I-Minocycline ingasebenzisana nezidakamizwa ezihlukahlukene ezivamile, njenge: 

• Utshwala 
• Anticoagulants
• CNS depressants 
• I-Duloxetine
• Imithi yokunaka ukushoda kwe-hyperactivity disorder, njenge-amphetamine ne-dextroamphetamine
• Imithi equkethe i-aluminium, i-calcium, insimbi, noma i-magnesium 
• Imithi ye-retinoid yomlomo, njenge-acitretin, isotretinoin
• Strontium
• I-Zolpidem

Udokotela wakho angase adinge ukulungisa imithamo noma atuse izinyathelo zokuphepha lapho ehlanganisa i-minocycline neminye imithi.

Ulwazi lwe-Minocycline Dosing

Odokotela bavame ukunikeza amaphilisi akhishwa isikhathi eside okwelashwa kwezinduna ngemithamo esekelwe esisindweni somzimba. Bavame ukunikeza amaphilisi akhishwa isikhathi eside okwelashwa kwezinduna ngemithamo esuselwe esisindweni somzimba. Isibonelo, iziguli ezinesisindo esingu-45-49 kg zithatha ama-45 mg kanye ngosuku, kanti lezo ezinesisindo esingamakhilogremu ayi-126-136 zingathatha u-135 mg nsuku zonke. 

Ezifweni eziningi, odokotela baqala ngamamiligremu angama-200, kulandele amamiligremu ayi-100 njalo emahoreni ayi-12. Umthamo omkhulu kufanele okungenani ube ngu-400 mg emahoreni angama-24. 

Ezifweni ezingaxakile ze-urethral, ​​endocervical, noma rectal ezibangelwa amagciwane athile, odokotela batusa u-100 mg njalo emahoreni ayi-12 okungenani izinsuku eziyisikhombisa. 

Odokotela babala umthamo wezingane ezingaphezu kweminyaka eyisishiyagalombili ngokuya ngesisindo somzimba, baqale ngo-4 mg/kg ekuqaleni, bese kuba ngu-2 mg/kg njalo emahoreni ayi-12.

Isiphetho

I-Minocycline antibiotic ithinta kakhulu ukwelashwa kwezifo ezihlukahlukene zamagciwane kanye nokuphathwa kwezinduna ezinzima. Ukuguquguquka kwawo nokusebenza ngempumelelo kwawo womabili amagciwane egram-positive kanye negram-negative kuwenza abe ithuluzi elibalulekile kwezokwelapha zesimanje. Nokho, kubalulekile ukukhumbula ukuthi nakuba i-minocycline inamandla, iza nemiphumela engemihle engase ibe khona kanye nezinyathelo zokuphepha ezidingekayo.

Ukusebenzisa kahle amaphilisi e-minocycline, ukulandela imithamo enqunyiwe kanye nokwazi ukuxhumana okungase kube khona neminye imithi kubalulekile ekwandiseni izinzuzo zayo. Njenganoma yimaphi ama-antibiotic, ukusetshenziswa okufanele kubalulekile ukuvimbela ukumelana nama-antibiotic kanye nokuqinisekisa imiphumela yesiguli. Izakhiwo eziyingqayizivele ze-Minocycline kanye nohlu olubanzi lwezinhlelo zokusebenza zigqamisa ukubaluleka kwayo okuqhubekayo kwezokwelapha.

Imibuzo Evame Ukubuzwa

1. Ingabe i-minocycline iyi-antibiotic ephephile?

I-Minocycline ngokuvamile iphephile uma isetshenziswa njengoba iqondiswa udokotela. Nokho, kungabangela imiphumela engemihle futhi kunezingozi ezithile. Kumelwe uqaphe mayelana nokusebenzisana okungase kube khona neminye imithi futhi wazise udokotela nganoma yikuphi ukungezwani komzimba nezinto ezithile noma izimo ezivele zikhona.

2. Ingabe i-minocycline iyisidakamizwa sezinhlungu?

Cha, i-minocycline ayiyona i-painkiller. Kuyi-antibiotic ephumelelayo ngokumelene nezifo ezihlukahlukene zebhaktheriya kanye nezinduna ezinzima. Nakuba ingase ibe nezindawo zokulwa nokuvuvukala, umsebenzi wayo oyinhloko ukumisa ukukhula kwamagciwane.

3. Ubani ongakwazi ukuthatha i-minocycline?

Abesifazane abakhulelwe, omama abancelisayo, nezingane ezingaphansi kweminyaka eyisishiyagalombili akufanele bathathe i-minocycline. Abantu abanesifo sesibindi noma sezinso, i-lupus, noma abangezwani ne-tetracycline kwemithi elwa namagciwane kufanele futhi ikugweme.

4. I-minocycline isetshenziswa isikhathi esingakanani?

Ubude besikhathi sokwelashwa kwe-minocycline siyahlukahluka futhi kuncike esimweni esiphathwayo. Nge-acne, isetshenziswa amasonto ayi-12. Kwezinye izifo, isifundo singase sibe sifushane. 

5. Ngingakwazi yini ukuthatha i-minocycline ebusuku?

Umuntu angathatha i-minocycline ebusuku, kodwa kubalulekile ukuthi angalali ngokushesha ngemva kokuyithatha. Umuntu kufanele ahlale eqondile okungenani imizuzu eyi-10 ngemva kokuthatha i-minocycline ukuze aqinisekise ukumuncwa okufanele.

6. Kufanele uyeke nini ukuthatha i-minocycline?

Umuntu kufanele ayeke ukuthatha i-minocycline uma ehlangabezana nemiphumela emibi kakhulu noma uma udokotela wethu eseluleka ukuba senze kanjalo. Kubalulekile ukuthi ungawuyeki umuthi uwedwa, ngisho noma izimpawu ziba ngcono, njengoba lokhu kungaholela ekungazweni nama-antibiotic noma ukubuya kokutheleleka.