I-Misoprostol

I-Misoprostol

I-Misoprostol umuthi wokwelapha ukwelapha ukufinyela kwesibeletho okungasebenzi. Ivimbela izilonda zesisu uma isetshenziswa nemithi elwa nokuvuvukala (ama-NSAID) njenge-Aspirin, i-Ibuprofen, i-Meloxicam, neminye. Ibuye isetshenziselwe ukwelapha ukopha kwangemva kokubeletha. Itholakala emakethe ngendlela yamaphilisi omlomo. I-World Health Organization yawubiza ngokuthi “umuthi obalulekile” ngenxa yokusetshenziswa kwawo okuningana ku-gynecology kanye nezimo zesisu.

Yiziphi ukusetshenziswa kweMisoprostol?

Uma usetshenziswa nama-NSAID, lo muthi uvimbela izilonda zesisu, ikakhulukazi uma unomlando wezilonda noma ingozi enkulu yokuthola izilonda. I-Misoprostol yehlisa amathuba okuba nezinkinga ezinkulu zezilonda ezifana nokopha ngokunciphisa inani le-asidi elithinta ulwelwesi lwesisu sakho. Lo muthi ubuye usetshenziswe nomunye umuthi (Mifepristone) ukumisa ukukhulelwa.

Ungayithatha kanjani futhi nini iMisoprostol?

• Landela imiyalelo kadokotela wakho mayelana nokusetshenziswa kwe-Misoprostol. Funda yonke imihlahlandlela yemithi noma imiyalelo ngaphambi kokusebenzisa noma yimuphi umuthi.
• I-Misoprostol ivamise ukuthathwa ngokudla izikhathi ezine ngosuku. Umthamo wakusihlwa kufanele kube owokugcina wosuku. Lapho usebenzisa lo muthi, ikakhulukazi emasontweni okuqala, ungase ube nesicanucanu, amajaqamba esiswini, noma uhudo. Isikhathi esivamile salezi zimpawu isonto elilodwa. Sicela wazise udokotela wakho uma inkinga yakho iqhubeka noma iba yimbi.
• Ukuze i-Misoprostol isebenze, kufanele iphuzwe njalo. Umthamo wokuqala wabesifazane akufanele uthathwe kuze kube usuku lwesibili noma lwesithathu lokuya esikhathini (ukuqinisekisa ukuthi abakhulelwe). Ungalokothi uyeke ukuthatha i-Misoprostol ngaphandle kokubonisana nodokotela wakho kuqala.

Iyini imiphumela emibi ye-Misoprostol?

I-Misoprostol inamandla okudala imiphumela emibi kakhulu. Shayela udokotela wakho ngokushesha uma ubona izimpawu ezilandelayo:

• Ubuhlungu besisu obuqhubekayo noma isifo sohudo.
• Izimpawu zokuphelelwa amanzi emzimbeni zihlanganisa isiyezi, ukudideka, ukoma kakhulu, nokuncipha komchamo.
• Lo muthi awuvamile ukubangela ukungezwani okukhulu komzimba. Noma kunjalo, thola usizo lwezokwelapha ngokushesha uma uthola noma yiziphi izimpawu ezilandelayo zokungezwani komzimba okukhulu: ukuqubuka, ukulunywa/ukuvuvukala, isiyezi esinzima, noma ukuphefumula kanzima.

Eminye imiphumela emibi ejwayelekile ye-misoprostol yile:

• Uhudo nobuhlungu besisu.
• Isicanucanu, ukuhlanza, ukuqunjelwa.
• Ukukhathala nomkhuhlane

Yiziphi izinyathelo zokuphepha okufanele zithathwe?

• Ngaphambi kokuthatha i-Misoprostol, yazisa udokotela wakho noma usokhemisi nganoma yikuphi ukuzwela okungenzeka ube nakho kuyo noma ezinye izinto.
• Ingozi yokopha esiswini ingase ikhuphuke uma uphuza njalo utshwala futhi ubhema. Nciphisa uphuzo oludakayo, futhi uyeke ukubhema.
• Uma uhlanganisa lo muthi ne-Mifepristone ukuze umise ukukhulelwa, mancane kakhulu amathuba okuthi kukhishwe isisu esingaphelele. Kufanele ugcine wonke ama-aphoyintimenti akho ahleliwe ukuze uqaphe ukuqhubeka kwakho futhi uhlale uqashwe udokotela wakho.
• Lindela ukopha esithweni sangasese sowesifazane ngemva kokuphuza imithi eyinhlanganisela, kodwa yazisa udokotela wakho ngokushesha uma uba nanoma yiziphi izimpawu ezingalindelekile ezifana nokopha okukhulu noma okuthatha isikhathi eside esithweni sangasese sangasese sowesifazane noma izinkomba zokutheleleka (ezifana nemfiva, ukugodola, noma ukuquleka).
• Ukukhulelwa: Njengoba kunethuba lokuthi ingase ilimaze ingane engakazalwa, lo muthi akufanele usetshenziselwe ukwelapha izilonda zesisu ngenkathi ukhulelwe. Sebenzisa izindlela ezithembekile zokulawula inzalo uma uneminyaka yobudala yokuzala ngenkathi uthatha i-Misoprostol. Yazisa udokotela wakho uma ukhulelwa noma usola ukuthi kungenzeka ukhulelwe.
• Ukuncelisa Ibele: Lo muthi ungena obisini lwebele. Noma kunjalo, kuyangabazeka ukuthi lesi sidakamizwa sizoba nomthelela kusana oluncelisayo. Kumele kukhulunywe nodokotela ngaphambi kokuncelisa.
• I-Misoprostol inengozi yokubangela ukukhubazeka kokuzalwa, ukuzalwa ngaphambi kwesikhathi, ukuphuka kwesibeletho, ukuphuphuma kwesisu, ukuphuphuma kwesisu okungaphelele, nokopha okungaba yingozi kwesibeletho. Akufanele isetshenziselwe ukuvimbela isilonda esiswini uma ukhulelwe.
• Uma kungenzeka ukuthi ukhulelwe, ukuhlolwa kokukhulelwa okungalungile kuyadingeka ngaphambi kokuqala lokhu kwelashwa. Ukwengeza, ukulawulwa kokuzalwa okuphumelelayo kufanele kusetshenziselwe ukuvimbela ukukhulelwa ngenkathi kwenziwa lokhu kwelashwa.

Kuthiwani uma ngiphuthelwa umthamo noma ngine-overdose ye-Misoprostol?

Thatha umthamo ogejiwe ngokushesha nje lapho uwukhumbula. Nokho, yeqa umthamo ongekho uma sekusondele isikhathi sokuthatha umthamo wakho olandelayo. 

Nciphisa ukudla kwakho, futhi ungasebenzisi ngokweqile. Impilo yakho ingase ihlupheke kakhulu ngenxa yalokho. Gcina isikhawu sesikhathi phakathi kwemithamo; gwema ukuthatha imithamo emibili ngesikhathi esisodwa. Thatha usizo oluphuthumayo lwezokwelapha uma umuntu ophuze ngokweqile ebonisa izimpawu eziyingozi njengokuquleka noma ukuphefumula kanzima.

Ukuqapha neminye imithi

I-Misoprostol ingase ihlanganyele nanoma yikuphi kokulandelayo:

• Ama-antacid
• Oxytocin

Bona udokotela wakho uma usebenzisa noma iyiphi yale mithi.

Yiziphi izimo zokugcina ze-Misoprostol?

• Gcina endaweni emnyama neyomile, kude nokukhanya kanye nomswakama, ku-25C (77F) noma ngaphansi.
• Ungangeni endlini yokugezela.
• Gcina izingane nezilwane ezifuywayo kude nanoma yimiphi imithi.
• Ngaphandle uma uqondiswa ngokuqondile, gwema ukuthela izidakamizwa endlini yangasese noma ukuzithela emiseleni. Sebenzisa indlela efanele yokulahla lapho umkhiqizo ungasadingeki noma usuphelelwe yisikhathi.

I-Misoprostol ikhombisa ngokushesha kangakanani imiphumela?

Uma ithathwa ngomlomo, iMisoprostol ithatha imizuzu engu-8 ukuze iqale ukusebenza futhi ihlala cishe amahora ama-2. Uma kuthathwa ngolimi oluncane, kuthatha imizuzu eyi-11 ukuqala ukusebenza futhi kuhlala cishe amahora ama-3. Uma kuthathwa ngesitho sangasese sowesifazane, kuthatha imizuzu engama-20 ukuqala ukusebenza futhi kuhlala cishe amahora ama-4.

I-Misoprostol vs Mifepristone

Imibuzo Evame Ukubuzwa

1. Uyini umehluko phakathi kweMisoprostol neMifepristone? 

I-Misoprostol ne-Mifepristone yomibili imithi esetshenziswa ekuhushuleni izisu okubangelwa imithi, kodwa ineqhaza elihlukile. I-Mifepristone, evame ukubizwa ngokuthi "iphilisi lokukhipha isisu," ngokuvamile isetshenziswa kuqala ukuvimbela i-hormone progesterone, edingekayo ekukhulelweni. Imvamisa ilandelwa yiMisoprostol, eyenza ukufinyela kwesibeletho kukhiphe ukukhulelwa.

2. Kuyini ukusetshenziswa okuyinhloko kweMisoprostol?

Ukusetshenziswa okuyinhloko kweMisoprostol kuyehluka. Isetshenziselwa ukunxenxa imihelo, ukulawula ukopha kwangemva kokubeletha, ukuvuthwa komlomo wesibeletho, nokwelapha izilonda zesisu. 

3. Ingabe i-Misoprostol inemiphumela engemihle?

Yebo, iMisoprostol ingaba nemiphumela engemihle. Lokhu kungase kuhlanganise isicanucanu, isifo sohudo, ubuhlungu besisu, ukufinyela kwesibeletho, ukopha esithweni sangasese sowesifazane, futhi kwezinye izimo, imiphumela emibi kakhulu njengokugqabuka kwesibeletho. Imiphumela emibi ingahluka kuye ngenjongo yokusetshenziswa.

4. Iyini imiphumela emibi ye-Misoprostol?

Imiphumela engemihle ye-Misoprostol ingabandakanya izinkinga zesisu njengesicanucanu, isifo sohudo, nobuhlungu besisu. Esimweni sokunqanyulwa kokukhulelwa, kungase futhi kubangele ukufinyela kwesibeletho kanye nokopha kwesitho sangasese sowesifazane. Imiphumela emibi kakhulu ingabandakanya ukuphuka kwesibeletho, nakuba lokhu kuyivelakancane. Imiphumela ethile engemihle etholwayo ingase yehluke kumuntu nomuntu.

Okubhekwayo:

https://www.drugs.com/Misoprostol.html https://medlineplus.gov/druginfo/meds/a689009.html
https://www.webmd.com/drugs/2/drug-6111/Misoprostol-oral/details

Umshwana wokuzihlangula: Ulwazi olunikezwe lapha alwenzelwe ukufaka iseluleko esivela kuchwepheshe wezokunakekelwa kwempilo. Ulwazi aluhloselwe ukumboza konke ukusetshenziswa okungenzeka, imiphumela engemihle, izinyathelo zokuphepha, nokusebenzisana kwezidakamizwa. Lolu lwazi aluhloselwe ukuphakamisa ukuthi ukusebenzisa umuthi othile kufanelekile, kuphephile, noma kuyasebenza wena noma omunye umuntu. Ukungabi bikho kwanoma yiluphi ulwazi noma isexwayiso mayelana nomuthi akufanele kuhunyushwe njengesiqinisekiso esicacile esivela enhlanganweni. Sikweluleka ngokuqinile ukuthi uthintane nodokotela uma kukhona okukukhathazayo ngomuthi futhi ungalokothi usebenzise umuthi ngaphandle kwencwadi kadokotela.