Naproxen

Naproxen

I-Naproxen uhlobo lwemithi elwa nokuvuvukala (i-NSAID). Isebenza ngokunciphisa amazinga e-hormone emzimbeni akhuthaza ukuvuvukala nokungakhululeki. I-Naproxen isetshenziselwa ukwelapha sokuqaqamba kwamalunga, amajaqamba okuya esikhathini, i-gout, i-bursitis, i-spondylitis, nobuhlungu noma ukuvuvukala okubangelwa noma iyiphi yalezi zimo. Ngaphezu kwezimo ezibalulwe lapha, iphinde ikhulule ubuhlungu obukhulu obuvela kwezinye izimo.

I-Naproxen sodium ne-Naproxen evamile yizinhlobo ezimbili ze-Naproxen ezitholakala kudokotela. Kunezinhlobo ezintathu zemithamo yomlomo ye-Naproxen evamile: amaphilisi okukhululwa ngokushesha, ukukhululwa okulibazisekayo, nokumiswa (uhlobo lwengxube yoketshezi). I-Naproxen Sodium yaziwa njengethebhulethi ekhishwa ngokushesha ngomlomo kanye nethebhulethi ekhishwa ngomlomo enwetshiwe. I-Naproxen iyatholakala futhi njengomuthi otholakala ngaphandle kwekhawunta. 

Ukuguquguquka kwayo nokusebenza ngempumelelo kwenza i-Naproxen ibe inketho ebalulekile yokuphatha izimo ezivuvukalayo nezibuhlungu. Kodwa-ke, abasebenzisi kufanele babambelele kumithamo enqunyiwe futhi, lapho becubungula ukutholakala kwayo ezitolo, balandele imihlahlandlela yokusebenzisa ukuze baqinisekise ukukhululeka okuphephile nokusebenzayo. Njenganoma yimuphi umuthi, ukuxhumana nochwepheshe wezokunakekelwa kwezempilo kuhle ukuze kunqunywe ifomu elifaneleka kakhulu kanye nesikali sezidingo zomuntu ngamunye.

Yiziphi izici zokusetshenziswa kwe-Naproxen?

Izinhlungu ezihlukahlukene zelashwa nge-Naproxen, kuhlanganise:

• Ukunciphisa Izinhlungu Ezimweni Ezihlukahlukene: I-Naproxen isetshenziselwa ukudambisa ubuhlungu obubangelwa izimo ezihlukahlukene, kuhlanganise nobuhlungu bekhanda, ubuhlungu bemisipha, i-tendonitis, ubuhlungu bamazinyo, namajaqamba okuya esikhathini.
• Izakhiwo Zokulwa Nokuvuvukala: Njengesidakamizwa esilwa nokuvuvukala (i-NSAID), i-Naproxen inciphisa ubuhlungu, ukuvuvukala, nokuqina kwamalunga okubangelwa isifo samathambo, i-bursitis, nokuhlasela kwegout.
• Indlela Yesenzo: Isebenza ngokuvimbela ukukhiqizwa komzimba kwezinto ezithile zemvelo ezibangela ukuvuvukala.
• Ukucatshangelwa Kwezimo Ezingamahlalakhona: Ezimweni ezingelapheki njengesifo samathambo, ukubonisana nochwepheshe wezokunakekelwa kwempilo kuhle ukuthi uhlole izindlela zokwelapha ezingasebenzisi izidakamizwa noma eminye imithi yokulawula izinhlungu.
• Ukuhlolwa Kwelebula: Kunconywa ukuthi uhlole amalebula omkhiqizo, noma ngabe asetshenziswe ngaphambilini, njengoba abakhiqizi bangase baguqule izithako. Imikhiqizo enemisindo efanayo ingase isebenze izinjongo ezihlukene ngezithako ezihlukile.

Kufanele ngithathe kanjani futhi nini i-Naproxen?

Lo muthi kufanele uphuzwe ngamanzi. Landela izikhombisi-ndlela ezikulebula kadokotela. Lo muthi akufanele uhlafuneke, usikwe noma ugaywe. Awagwinye ngokuphelele amaphilisi. Ungawuthatha lomuthi ngokudla noma ngaphandle kokudla. Uma ikwenza ube nesicanucanu, yithathe kanye nokudla. Kuze kube yilapho udokotela wakho ekweluleka ngenye indlela, qhubeka uyithatha. Ukushintsha amabhrendi, ukugxilisa ingqondo, noma izinhlobo zemithi kungase kuguqule izidingo zakho zomthamo. Xhumana nosokhemisi wakho uma unokukhathazeka mayelana nohlobo lwe-Naproxen oluthathayo.

Imithamo yezingane inqunywa isisindo; ngakho, noma yikuphi ukulungisa kungase kube nomthelela.

I-Naproxen isebenza kanjani?

I-Naproxen iyisidakamizwa esilwa nokuvuvukala (i-NSAID) esivame ukusetshenziselwa ukunciphisa ubuhlungu, ukuvuvukala, nokushisa. Isebenza ngokuvimbela umsebenzi we-cyclooxygenase (COX) enzymes. Kunezinhlobo ezimbili zama-enzyme e-COX emzimbeni: i-COX-1 ne-COX-2.

• Ukuvinjelwa kwama-enzyme e-COX: I-Naproxen ivimbela ngokuyinhloko kokubili ama-enzyme e-COX-1 ne-COX-2. Ama-enzyme e-COX anesibopho sokukhiqiza ama-prostaglandin, okuyizinto ezinjenge-hormone ezihilelekile ekuvuvukeni, ekuboniseni ubuhlungu, nokusabela kwemfiva.
• Ukunciphisa ukuhlanganiswa kwe-prostaglandin: Ngokuvimbela ama-enzyme e-COX, i-naproxen inciphisa ukuhlanganiswa kwe-prostaglandin. I-Prostaglandin ingabalamuli ababalulekile bokuvuvukala nobuhlungu. Lapho ukukhiqizwa kwabo kuncishisiwe, impendulo yokuvuvukala iyancipha, okuholela ekunciphiseni ubuhlungu nokuvuvukala.
• Ukunciphisa ubuhlungu kanye nemiphumela eqeda ukuvuvukala: Ikhono le-Naproxen lokunciphisa amazinga e-prostaglandin liphumela ekunciphiseni ubuhlungu kanye nemiphumela yokulwa nokuvuvukala. Isetshenziselwa ukwelapha izimo ezihlukahlukene ezifana nesifo samathambo, ukuqaqamba kokuya esikhathini, ubuhlungu bemisipha, ikhanda elibuhlungu, nezinye izimo ezivuvukalayo.

Iyini imiphumela emibi ye-Naproxen?

Amaphilisi omlomo e-Naproxen angase abangele ukozela. Akufanele ushayele, usebenzise amathuluzi, noma uhlanganyele kweminye imisebenzi efuna ukunakwa kuze kube yilapho usuqiniseka ukuthi ungakwazi ukusebenza ngendlela evamile. Eminye imiphumela emibi yalo muthi kungenzeka. Okulandelayo imiphumela emibi evame kakhulu ye-Naproxen oral tablet:

• Ubuhlungu besisu
• Uhudo noma ukuqunjelwa
• isilungulela
• isiyezi
• I-nausea nokuhlanza

Le miphumela engemihle ivamise ukunyamalala ezinsukwini ezimbalwa noma emasontweni ambalwa. Bonana nodokotela wakho uma ziba zimbi kakhulu noma zingashabalali. Nazi izibonelo zemiphumela emibi kakhulu nezimpawu ezihambisanayo:

• Izinkinga zokukhuluma
• ubuhlungu besifuba
• Ukuvuvukala kobuso noma umphimbo
• Ukuphefumula kanzima noma ukuntula umoya
• Ubuthakathaka ohlangothini olulodwa noma engxenyeni ethile yomzimba
• Ukuhlasela kwesifuba somoya kubantu abanesifuba somoya
• Ukuvuvukala kobuso noma umphimbo
• Umfutho wegazi ophezulu

Yiziphi izinyathelo zokuphepha okufanele zithathwe?

• Gwema utshwala. Kungenza ukopha kwesisu kube maningi kakhulu.
• I-Aspirin namanye ama-NSAID akufanele athathwe ngaphandle uma udokotela wakho ekuyala.
• Ngaphambi kokusebenzisa noma yimuphi omunye umuthi wezinhlungu, isifo samathambo, imfiva, noma i-edema, thintana nodokotela wakho. I-Aspirin, i-salicylates, noma eminye imithi efana ne-Naproxen itholakala emithini eminingi ye-over-the-counter. 
• Akufanele usebenzise i-Naproxen ngesikhathi ukhulelwe ngaphandle uma udokotela wakho ekuyala. Ukusetshenziswa kwe-NSAID emasontweni okugcina angu-20 okukhulelwa kungase kubangele izinkinga ezinkulu zenhliziyo noma zezinso kumntwana ongakazalwa kanye nobunzima bokukhulelwa.
• Ukuzwela kwakho elangeni kungase kukhule uma usebenzisa lo muthi. Thatha ikhefu njalo elangeni. Yeqa amalambu elanga namadokodo okushuka. Uma ungaphandle, sebenzisa i-sunscreen kanye nesigqoko.
• Izidakamizwa ze-NSAID, njenge-Naproxen, ngezinye izikhathi zingabangela izinkinga zezinso. Uma uphelelwe amanzi emzimbeni, yiba yokumelwa yinhliziyo noma ukugula kwezinso, umuntu omdala omdala, noma sebenzisa imithi ethile, izinkinga zingase ziphakame. Ukuze ugweme ukuphelelwa amanzi emzimbeni, dla uketshezi oluningi njengoba uyalelwe udokotela wakho

Kuthiwani uma ngiphuthelwa umthamo we-Naproxen

I-Naproxen ivame ukusetshenziswa njengoba kudingeka, ngakho ungase ungabi nesimiso somthamo. Uma ulandela isimiso bese ukhohlwa ukuphuza umthamo, kwenze lokho ngokushesha nje lapho ukhumbula. Yeqa umthamo ongekho uma umthamo wakho olandelayo uzofika maduze. Gwema ukuthatha imithamo emibili ngesikhathi esisodwa ukuze uvale umthamo ongekho.

Izixwayiso ze-Naproxen

I-Naproxen, uhlobo lwesidakamizwa esilwa nokuvuvukala (i-NSAID), inethuba elingandile lokwandisa ingozi yokuhlaselwa yinhliziyo noma unhlangothi. Le ngozi ikhona noma nini phakathi nokusetshenziswa kwayo kodwa iba maningi amathuba okuthi isetshenziswe isikhathi eside, ikakhulukazi kubantu abadala asebekhulile noma labo abanesifo senhliziyo, umfutho wegazi ophakeme, isifo sikashukela, noma umlando womndeni wesifo senhliziyo. Gwema ukuthatha lo muthi ngaphambi noma ngemuva kokuhlinzwa kwe-heart bypass (CABG). Kukhona futhi ingozi ephansi kodwa engathi sína yokopha okungaba nokufa okuvela esiswini noma emathunjini, okungenzeka kungazelelwe. Abantu abadala asebekhulile basengozini enkulu kule ngozi. Kubalulekile ukuqapha, futhi ukunakekelwa kwezokwelapha ngokushesha kuyelulekwa uma kukhona ukukhathazeka kuphakama ngenkathi usebenzisa lo muthi.

Yiziphi izimo zokugcina ze-Naproxen?

• Gcina ekamelweni lokushisa eliphakathi kuka-20 no-25 degrees Celsius (68 kanye no-77 degrees F).
• Gcina ukoma komuthi futhi uwuvikele kumswakama. Qinisekisa ukuthi isiqukathi sivaleke ngokuqinile futhi ugweme ukusibeka endaweni eshisa kakhulu.
• Lahla noma iyiphi i-Naproxen engasetshenziswa ngemva kokuba usuku lokuphelelwa yisikhathi seludlulile.

Ukuqapha neminye imithi

Uma usebenzisa i-antidepressant, njenge-citalopram, i-escitalopram, i-fluoxetine, i-fluvoxamine, i-paroxetine, i-sertraline, noma i-vilazodone, bona udokotela wakho ngaphambi kokusebenzisa i-Naproxen. Noma iyiphi yalezi zidakamizwa ingase inyuse ingozi yokopha noma izibazi lapho usetshenziswa ne-NSAID. Buza udokotela wakho ukuthi kulungile yini ngawe ukusebenzisa lo muthi uma uthatha noma yimiphi imithi elandelayo:

• I-Cholestyramine
• Digoxin
• I-Methotrexate
• Lithium
• I-Probenecid
• I-Pemetrexed
• Imithi yokuquleka
• Igazi elincane
• Umuthi wenhliziyo noma wegazi
• Umuthi we-insulin noma wesifo sikashukela somlomo.

I-Naproxen ibonisa ngokushesha kangakanani imiphumela?

Ngemva kokuthatha i-Naproxen, kufanele uqale ukuzizwa ungcono esikhathini esingangehora. Uma uthatha i-Naproxen kabili ngosuku njengoba uyaliwe, kungathatha izinsuku ezingafika kwezi-3 ukuze iqale ukusebenza ngempumelelo.

Umthamo we-Naproxen

Umthamo we-Naproxen ungahluka kuye ngesimo esiphathwayo, indlela umuntu asabela ngayo emuthini, nezinye izici.

• Abantu abadala:
  • Ukunciphisa ubuhlungu: Umthamo wokuqala uvamise ukuba ngu-250 mg, 375 mg, noma 500 mg kabili ngosuku.
  • Ezimweni ezivuvukalayo ezifana nesifo samathambo: Umthamo wokuqala uvamise ukuba ngu-250 mg, 375 mg, noma 500 mg kabili ngosuku, ngesilinganiso esiphezulu sansuku zonke esingu-1500 mg.
• Abadala:
  • Imithamo ephansi ingase imiselwe iziguli esezikhulile, ikakhulukazi lezo ezinokukhubazeka kwezinso noma ezinye izinkinga zempilo. Kubalulekile ukulandela isiqondiso sochwepheshe bezempilo.
• Udokotela wezingane:
  • I-Naproxen ngokuvamile ayinconyelwe izingane ezingaphansi kweminyaka engu-2 ubudala ngaphandle uma iqondiswa umhlinzeki wezempilo.
  • Umthamo wezingane unqunywa ngokusekelwe isisindo kanye neminyaka, futhi kubalulekile ukulandela imiyalelo ethile enikezwa udokotela wezingane.
• Isikhathi Sokusetshenziswa:
  • I-Naproxen ivame ukuthathwa ukuze kukhululwe izimpawu zesikhashana. Ukusetshenziswa isikhathi eside kufanele kube ngaphansi kokuqondisa komhlinzeki wezempilo ngenxa yengozi yemiphumela emibi yesisu kanye nezinye izinkinga.
• Ukucatshangelwa Okukhethekile:
  • Abantu abanezimo ezithile zezokwelapha ezifana nesifo sezinso, isifo senhliziyo, noma umlando wokopha emathunjini angase adinge imithamo ephansi noma ukuqapha okuseduze.
  • Ngaso sonke isikhathi thatha i-Naproxen ngokudla noma ubisi ukuze usize ukunciphisa ingozi yokucasuka kwesisu.

Naproxen Vs Ibuprofen