I-Nimesulide

I-Nimesulide

I-Nimesulide iyisidakamizwa esingeyona i-steroidal eqeda ukuvuvukala (i-NSAID) enemiphumela ye-analgesic ne-antipyretic ekhethwa ngokuyinhloko i-COX-2. Lo muthi usetshenziselwa ukukhulula ubuhlungu. Ikhulula ubuhlungu obuncane kuya kobumaphakathi obubangelwa amajaqamba kanye ne-osteoarthritis kubantu abadala kanye nentsha engaphezu kweminyaka engu-12. I-Nimesulide inciphisa ukushuba kwezimpawu zobuhlungu ezidluliselwa ebuchosheni futhi ivimbele ukwakheka kwe-prostaglandin (izinto ezidlulisa ubuhlungu nezimpawu zokushisa ebuchosheni).

Yiziphi izinkomba zokusetshenziswa kwe-Nimesulide?

Uma kunezinkinga ezihlangene, njenge-arthritis, i-Nimesulide isetshenziselwa ukunciphisa ubuhlungu, ukuvuvukala nokuvuvukala. Ngaphezu kwalokho, inciphisa ubuhlungu obubangelwa ukuhlinzwa, ubuhlungu bamazinyo, ama-sprains nama-sprains, kanye nendlebe, ikhala, nobuhlungu bomphimbo. Ngaphezu kwalokho, isetshenziselwa ukwelapha i-osteoarthritis kanye ukunqamuka kokuya esikhathini ezibuhlungu kakhulu. Ngaphezu kwalokho, inciphisa ubuhlungu obuncane kuya kobunzima obulethwa ama-muscle namajoint sprains kanye nezinkinga. Kodwa izingane ezingaphansi kweminyaka engu-12 akufanele zisebenzise i-Nimesulide, njengoba inengozi enkulu yokulimala kwesibindi.

Kanjani futhi nini ukuthatha "Nimesulide"?

I-Nimesulide itholakala ngezindlela ezihlukahlukene, okuhlanganisa amaphilisi, isiraphu, amaphilisi, ithebhulethi ye-DT, ithebhulethi MD, imijovo, amaconsi omlomo, izixazululo, nejeli. Ngemva kokuhlola isimo sakho sezokwelapha, udokotela wakho uzokhetha ifomu elingcono kakhulu lesilinganiso kanye nenani lomuthi. Esibhedlela, udokotela wakho angakunikeza imijovo ye-Nimesulide.

Thatha ithebhulethi yakho noma i-capsule ngamanzi futhi uyithathe iphelele. Ungalokothi uyidle, uyiphule, noma uyichoboze. Uma ithebhulethi iqeda umlomo, yibeke olimini lwakho. Ivumele ukuthi incibilike noma ihlukane. Ngaphambi kokugwinya, ithebhulethi kufanele ichithe ngokuphelele emlonyeni wakho. Ngaphambi kokusebenzisa iphilisi elihlakazekayo, funda ilebula. Chaza iphilisi ngenani elidingekayo lamanzi futhi uphuze okuqukethwe. Gcoba ibhodlela lokumiswa ngokucophelela ngaphambi kokulisebenzisa. Thatha inani elishiwo ngomlomo usebenzisa inkomishi yokulinganisa/iconsi elifakwe ephaketheni.

Iyini imiphumela emibi ye-Nimesulide?

I-Nimesulide kufanele ithathwe kuphela ngaphansi kokuqondiswa kochwepheshe bezokwelapha abaqeqeshiwe. Ukusetshenziswa isikhathi eside kungase kulimaze isibindi noma kubangele imiphumela engemihle ebalulekile, okuhlanganisa ukopha emathunjini noma izinkinga zezinso. Eminye imiphumela emibi kakhulu ye-Nimesulide yilezi:

• I-Acid noma isisu esimuncu
• isiyezi
• Ubuhlungu besisu namajaqamba
• Ukutheleleka kwesikhumba
• Ukwandisa ama-enzyme wesibindi
• I-nausea nokuhlanza
• Uhudo
• Izinkinga zokujiya kwegazi

Uma unezimpawu eziphawulekayo, khuluma nodokotela wakho ngokushesha ukuze uthole isiqondiso. Noma kunjalo, uma unemiphumela emibi evela ku-Nimesulide, yeka ukuyiphuza. Izinzuzo zalo muthi zidlula imiphumela emibi. Ngakho udokotela angase asikisele ukuthi uyisebenzise ngemva kokuhlola isimo sakho. Abaningi balabo abasebenzisa lo muthi abatholi imiphumela engemihle. Kodwa-ke, thola usizo lwezokwelapha ngokushesha uma uhlangabezana nemiphumela emibi kakhulu ye-Nimesulide.

Yiziphi izinyathelo zokuphepha okufanele zithathwe?

• Buza udokotela wakho ngaphambi kokusebenzisa i-Nimesulide uma unokungezwani nezidakamizwa noma uguliswa yinoma yiziphi ezinye izinto. Umkhiqizo ungaba nezinto ezingasebenzi ezibangela ukungezwani komzimba noma ezinye izinkinga ezinzima.
• I-Nimesulide ayelulekisiwe ekudakweni kotshwala, ukuluthwa izidakamizwa, noma izinkinga zokuqunjelwa, ezinganeni, ngesikhathi sokukhulelwa, noma komama abancelisayo.
• Uma unesifuba somoya, ukuhlinzwa kwenhliziyo kwakamuva, isifo senhliziyo, isilonda esiswini, ukopha kwakamuva emathunjini, umlando wokungezwani komzimba nanoma yimiphi imithi, noma enye yalezi zimo, sicela wazise udokotela wakho ngaphambi kokuthatha i-Nimesulide.
• Amaphilisi e-Nimesulide angase abangele ukuba nekhanda elikhanyayo noma izinkinga zamehlo. Ngemva kokuthatha lo muthi, gwema ukuzibandakanya emisebenzini efana nokusebenzisa umshini noma ukushayela imoto.
• Yeka ukusebenzisa lo muthi kuphela ngemva kokukhuluma nodokotela wakho. Noma yimiphi imiphumela emibi ngemva kokuyithatha kufanele ibikwe kudokotela wakho.

Kuthiwani uma ngiphuthelwa umthamo noma ngidlula umthamo ku-Nimesulide?

Umzimba wakho ngeke uthinteke uma weqa umthamo owodwa noma emibili ye-Nimesulide. Umthamo oweqiwe awunayo imiphumela emibi. Kwezinye izimo, uma uphuthelwa umthamo, udokotela wakho angase akukhuthaze ukuthi uphuze imithi enconyiwe ngokushesha ngangokunokwenzeka ngaphandle uma sekuyisikhathi somthamo olandelayo.

Ukweqisa izidakamizwa ngengozi kungenzeka. Kungenzeka ukuthi ukuphuza amaphilisi amaningi e-Nimesulide kunalawo anconyiwe kuzolimaza umzimba wakho. Ukweqisa izidakamizwa kungase kubangele isimo esiphuthumayo sezokwelapha. Xhumana nodokotela wakho noma isibhedlela esiseduze esimeni esinjalo.

Yiziphi izimo zokugcina i-Nimesulide?

• Umuthi kufanele ugcinwe ekamelweni lokushisa, phakathi kuka-20 no-25C (68 no-77F).
• Gcina le mithi endaweni epholile, eyomile kanye nebhokisi lokuqala noma isitsha kuze kufike isikhathi sokuyithatha.
• Gcina lo muthi ukude nalapho izingane zingakwazi ukufinyelela kuzo futhi zingabonakali.

Ukuqapha neminye imithi 

I-Nimesulide ingase ihlanganyele nemithi yesimiso sokuphefumula, i-blood thinners, i-antidiabetics (i-insulin), i-anti-epileptics, ama-anti-cancer agents, izidakamizwa ezithonya isimiso somzimba sokuzivikela, ama-antacids, nemithi elwa ne-HIV (didanosine). Gwema ukudla imikhiqizo yobisi njengobisi, iyogathi, noma iziphuzo ezine-calcium eyengeziwe.

I-Nimesulide ibonisa ngokushesha kangakanani imiphumela?

Phakathi nemizuzu engu-15 yokuphuza umuthi, i-Nimesulide ikhulula kakhulu ubuhlungu nokuvuvukala.

Ukuqhathaniswa komuthi weNimesulide ne-Aceclofenac

Imibuzo Evame Ukubuzwa

1. Isetshenziselwa ini i-Nimesulide?

I-Nimesulide iyisidakamizwa esilwa nokuvuvukala (i-NSAID) esisetshenziselwa ukudambisa izinhlungu nokuvuvukala ezimeni ezifana ne-osteoarthritis, i-rheumatoid arthritis, nobuhlungu obukhulu.

2. Isebenza kanjani i-Nimesulide?

I-Nimesulide isebenza ngokuvimbela ukukhiqizwa kwezinto ezithile (i-prostaglandins) ezibangela ubuhlungu nokuvuvukala emzimbeni.

3. Ngingakwazi yini ukuthatha i-Nimesulide kanye nokudla?

I-Nimesulide ingathathwa ngokudla noma ngaphandle kokudla. Nokho, ukuyithatha nokudla kungase kusize ukunciphisa ingozi yokucasuka kwesisu.

4. Yimiphi imiphumela emibi evamile ye-Nimesulide?

Imiphumela engemihle evamile ingase ihlanganise ubuhlungu besisu, isicanucanu, ukungagayeki kahle kokudla, nesiyezi. Imiphumela emibi kakhulu ingase ibe khona, ngakho-ke kubalulekile ukubika noma yiziphi izimpawu ezingavamile kumhlinzeki wakho wokunakekelwa kwezempilo.

5. Ingabe i-Nimesulide ingasetshenziselwa umkhuhlane?

I-Nimesulide inezici zokuqeda ukuvuvukala futhi ingasetshenziswa ukunciphisa ukushisa kanye nokwelapha ubuhlungu nokuvuvukala. Kodwa-ke, kubalulekile ukulandela umthamo onconywayo futhi uxhumane nochwepheshe bezempilo.

References:

https://www.ncbi.nlm.nih.gov/books/NBK547948/#:~:text=Nimesulide%20is%20generally%20well%20tolerated,peripheral%20edema%20and%20hypersensitivity%20reactions. https://www.ncbi.nlm.nih.gov/books/NBK547948/

Umshwana wokuzihlangula: Ulwazi olunikezwe lapha alwenzelwe ukufaka iseluleko esivela kuchwepheshe wezokunakekelwa kwempilo. Ulwazi aluhloselwe ukumboza konke ukusetshenziswa okungenzeka, imiphumela engemihle, izinyathelo zokuphepha, nokusebenzisana kwezidakamizwa. Lolu lwazi aluhloselwe ukuphakamisa ukuthi ukusebenzisa umuthi othile kufanelekile, kuphephile, noma kuyasebenza wena noma omunye umuntu. Ukungabi bikho kwanoma yiluphi ulwazi noma isexwayiso mayelana nomuthi akufanele kuhunyushwe njengesiqinisekiso esicacile esivela enhlanganweni. Sikweluleka ngokuqinile ukuthi uthintane nodokotela uma kukhona okukukhathazayo ngomuthi futhi ungalokothi usebenzise umuthi ngaphandle kwencwadi kadokotela.