I-Estrogen

I-Estrogen

Ubuwazi ukuthi i-estrogen idlala indima ebalulekile emizimbeni yethu ngaphandle nje kwempilo yokuzala? Le hormone enamandla ithonya izici ezihlukahlukene zenhlalakahle yethu, kusukela ekuqineni kwamathambo kuya ekulawuleni imizwa. I-Oestrogen, evame ukubizwa ngokuthi i-hormone yocansi yabesifazane eyinhloko, inomthelela omkhulu kubo bobabili abesilisa nabesifazane, ibumba izici zomzimba kanye nokulawula imisebenzi ebalulekile yomzimba.

Kulesi sihloko, sizohlola umhlaba we-estrogen kanye nezinhlobo zayo eziningi, okuhlanganisa amaphilisi e-estrogen nezithasiselo. Sizoxoxa ngokusetshenziswa kwemithi ye-estrogen, ukuthi isebenza kanjani emzimbeni, kanye nezinzuzo zayo ezingaba khona empilweni yabesifazane. Ukwengeza, sizohlola ukubaluleka kokugcina amazinga e-estrogen afanele, imiphumela yokungalingani, nokuthi odokotela bawasebenzisa kanjani amaphilisi e-estrogen kwabesifazane ukuze babhekane nezimo ezihlukahlukene zezokwelapha. 

Iyini i-Oestrogen?

I-Estrogen iyi-hormone ye-steroid edlala indima ebalulekile ekulawuleni ukuzala kwezilwane ezincelisayo. Ngokuyinhloko yaziwa ngokuthi i-hormone yocansi yabesifazane kodwa ikhona kokubili kwabesilisa nabesifazane. Ama-ovari, izindlala ze-adrenal, nezicubu ze-adipose zikhiqiza i-estrogen. Kwabesifazane, i-estrogen ilungiselela ukukhulelwa kwesibeletho nezinye izitho zokuzala. Iphinde ilawule umjikelezo wokuya esikhathini, ikhuthaze ukukhula kwezinwele ze-pubic nezangaphansi kwekhwapha, futhi igcine amandla amathambo ngokusebenzisana calcium, i-vitamin D, nezinye izakhi ezibalulekile.

Kunezinhlobo ezintathu eziyinhloko ze-estrogen: i-estrone, i-estradiol, ne-estriol. I-Estradiol uhlobo oluvame kakhulu kwabesifazane phakathi neminyaka yabo yokuzala. Amazinga e-Estriol ayakhuphuka ngesikhathi sokukhulelwa ukusiza isibeletho sikhule futhi silungiselele umzimba ukubeletha. I-Estrogen ithonya izitho ezihlukahlukene, kuhlanganise namaqanda, isitho sangasese sowesifazane, isibeletho, namabele. Ivuselela ukukhula kwama-follicles amaqanda, ithuthukise ulwelwesi lwesibeletho, futhi ibambe iqhaza ekwakhekeni kwezicubu zebele.

Ukusetshenziswa kwethebhulethi ye-Estrogen

Amaphilisi e-Estrogen asebenza ngezinjongo ezihlukahlukene zezokwelapha. Odokotela bazinikeza ngokuyinhloko ukuze zilawule izimpawu zokunqamuka kokuya esikhathini njengengxenye yokwelapha okushintshwa kwamahomoni. Amaphilisi e-Estrogen asiza ekudambiseni ukushisa, ukumelela kwesisu, kanye nocansi olubuhlungu. Baphinde babhekane nokushintsha kwemizwa, ukuphazamiseka kokulala, ukukhathazeka, nokuncipha kwesifiso socansi esihambisana nokunqamuka kokuya esikhathini.

Ngaphandle kokunqamuka kokuya esikhathini, amaphilisi e-estrogen anezinye izinto ezibalulekile ezisetshenziswayo: 

• Baphatha ukungasebenzi kahle kwe-ovarian kanye nezinye izinkinga ze-ovarian. 
• Odokotela bangase bazinikeze izinhlobo ezithile zezinduna nezinye izimo zomdlavuza wendlala yesinye. 
• Amaphilisi e-Estrogen angasiza ekuthombeni okubambezelekile.
• Amaphilisi e-Estrogen supplement abuye abambe iqhaza ekuvimbeleni ukulahleka kwamathambo (i-osteoporosis) kwabesifazane abangemva kokuya esikhathini. 
• Kwezinye izimo, odokotela bawasebenzisela ukwelapha izinhlobo ezithile zomdlavuza webele osusabalele kwezinye izingxenye zomzimba. 
• Abesifazane abanezimo ezifana ne-hypogonadism noma ukwehluleka kwe-ovarian okuyinhloko bangase bazuze kumathebulethi e-estrogen ukuze bangezelele ekukhiqizeni ama-hormone emvelo emizimbeni yabo.

Indlela Yokusebenzisa I-Estrogen Tablets

• Odokotela banquma amaphilisi e-estrogen ukuthi aphuzwe ngomlomo kanye ngosuku, ngokuvamile ngesikhathi esifanayo. 
• Ukuthatha imithi njengoba nje udokotela wakho eyala kubalulekile, ngaphandle kokushintsha umthamo noma imvamisa.
• Iziguli kufanele ziphuze amaphilisi ngokudla noma ngaphandle kokudla. Labo abahlushwa isicanucanu bangathatha amaphilisi kanye nokudla ukuze banciphise ukungaphatheki kahle. 
• Ngama-transdermal patches, abasebenzisi kufanele bawagcobe esikhumbeni esihlanzekile, esomile esingaphansi kwesisu, ezinqulwini, noma ezinqeni, bagweme amabele nokhalo. 
• Kumaphilisi akhishwa isikhathi eside, ukuwagwinya ngaphandle kokuwachoboza, ukuwahlafuna, noma ukuncibilika kubalulekile. Lokhu kuqinisekisa ukumuncwa okufanele kanye nempumelelo yemithi.

Imiphumela Emibi Yezibhebhe Estrogen

Amaphilisi e-Estrogen supplement angabangela imiphumela emibi eminingana evamile, njenge: 

• Isisu sithukuthele
• I-nausea nokuhlanza
• Ukuvimbela
• Ububele besisu
• bekhanda
• Izinguquko zesisindo

Abanye abantu bangase babhekane nokusabela okubi kakhulu, okuhlanganisa: 

• Ukushintsha kwemizwa, ukucindezeleka, nezimpawu zengqondo, njengokulahlekelwa inkumbulo
• Izigaxa zamabele
• Ukopha okungavamile kwesitho sangasese sowesifazane
• Ukwanda kokucasuka kwesitho sangasese sowesifazane
• Ukwanda noma ukukhishwa okusha kwesitho sangasese sowesifazane
• Ubuhlungu obukhulu besisu
• Ukuvuvukala kwezandla, amaqakala, noma izinyawo 
• Ezimweni ezingavamile, amaphilisi e-estrogen angaholela ezinkingeni ezinkulu ezivela emahluleni egazi, njenge kokuhlaselwa yisifo senhliziyo noma imivimbo. Iziguli kufanele zifune isiqondiso sezokwelapha ngokushesha uma zizwa ubuhlungu besifuba, ikhanda elibuhlungu kungazelelwe, ubuthakathaka ohlangothini olulodwa lomzimba, noma inkinga yokukhuluma. 
• Nakuba kungavamile, ukungezwani okukhulu komzimba kungase kukhule, kubangele izimpawu ezifana nokuqubuka kwesikhumba, ukulunywa, ukuvuvukala, ukuqina okukhulu. isiyezi, noma ukuphefumula kanzima.

Ukuqapha

• Ukunamathela Esilinganisweni Esinqunyiwe: Iziguli kufanele ziphuze amaphilisi e-estrogen kuphela njengoba ziqondiswa udokotela wazo. Akufanele zeqe umthamo noma ubude besikhathi esinqunyiwe. Kubalulekile ukuphuza umuthi ngesikhathi esifanayo nsuku zonke ukuze unciphise imiphumela engemihle futhi uthuthukise ukusebenza kahle. 
• I-Allergies: Abantu kufanele bazise udokotela wabo nganoma yikuphi ukungezwani komzimba, izimo zezokwelapha, noma eminye imithi abayithathayo. 
• Ukubhema: Ukubhema ngenkathi usebenzisa amaphilisi e-estrogen kwandisa ingozi yemiphumela emibi kakhulu. Ngakho, kugweme.
• I-Gynecological Cancers: Abesifazane abopha ngendlela engavamile esithweni sangasese noma abanomlando womdlavuza othile, njengomdlavuza webele, wesibeletho, noma we-ovary, kufanele baqaphele.
• Izimo Zezokwelapha: Abantu abanezimo ezithile zezokwelapha kufanele futhi bazise udokotela wabo ngaphambi kokuthatha lo muthi. Lokhu kungase kuhlanganise:
  • Isifo sesibindi
  • Isifo sezinso
  • Umlando we-thromboembolism noma i-thrombophlebitis
  • Ukungahambisani kwesibeletho
  • Stroke
  • Ukuphazamiseka kokujiya kwegazi
  • Amazinga aphezulu e-cholesterol
  • Lupus
  • I-Hypothyroidism
  • ukuquleka
  • migraine
  • Izimo zesibeletho, njenge fibroids noma i-endometriosis

Indlela Ithebhulethi Ye-Estrogen Esebenza Ngayo

Amaphilisi e-Estrogen aqukethe amahomoni okwenziwa alingisa i-estrogen yemvelo yomzimba. Lawa maphilisi angena egazini futhi abophe ama-estrogen receptors kuwo wonke umzimba. Zithinta amasistimu wezitho ezahlukahlukene, kufaka phakathi umgudu wokuzala, amathambo, nobuchopho. Amaphilisi asebenza ngokwengeza noma ngokushintsha ukukhiqizwa kwe-estrogen yemvelo yomzimba, eyancipha ngesikhathi sokunqamuka kokuya esikhathini noma ezimweni ezithile zezokwelapha. Zisiza ukulawula umjikelezo wokuya esikhathini, ukugcina ukuminyana kwamathambo, nokunciphisa izimpawu ezinjengokushisa okushisayo nokoma kwesitho sangasese sowesifazane. Amaphilisi e-Estrogen nawo athinta i-lipid metabolism, akhuphule i-high-density lipoproteins (HDL) kanye nokuncipha kwe-low-density lipoproteins (LDL). Lesi senzo singanciphisa ingozi ye-coronary artery disease kwabesifazane abadlule kokuya esikhathini lapho sisetshenziswa kusenesikhathi. Ukusebenza kwamaphilisi kuncike emandleni awo okugcina amazinga ehomoni azinzile emzimbeni.

Ngingathatha I-Estrogen Ngeminye Imithi?

Amaphilisi e-Estrogen angasebenzisana nemithi eminingi, ngakho-ke kubalulekile ukubonana nodokotela ngaphambi kokuwahlanganisa. Eminye imikhiqizo engase ihlanganyele ne-estrogen ihlanganisa: 

• Abacavir
• Abemaciclib
• I-Aromatase inhibitors
• I-Fezolinetant
• Fulvestrant
• Levothyroxine
• I-Ospemifene
• I-Raloxifene
• Tamoxifen
• Toremifene
• I-Tranexamic acid

Ulwazi Lomthamo

Imithamo ye-Estrogen iyahlukahluka kuye ngesimo esithile kanye nezidingo zesiguli ngasinye. 

• Ngezimpawu Ze-Postmenopausal: Imithamo yomlomo ngokuvamile isukela ku-0.5 kuya ku-2 mg nsuku zonke, kuyilapho ama-transdermal patches eletha i-0.025 kuya ku-0.1 mg/amahora angu-24. 
• Nge-Atrophic Vaginitis: Okhilimu besitho sangasese sowesifazane, izinto ezifakwayo, nezindandatho zinikeza ukwelashwa kwendawo. 
• Nge-Hypoestrogenism: Imithamo yomlomo iqala ku-1 kuya ku-2 mg nsuku zonke, kunezinketho ze-transdermal ezitholakalayo. 
• Ukwelashwa Komdlavuza Webele Webele: Kubandakanya imithamo ephezulu ye-estrogen engu-10 mg ngomlomo kathathu ngosuku. 
• Ngokuvimbela I-Osteoporosis: Imithamo isukela ku-0.5 kuye ku-2 mg ngomlomo nsuku zonke. Nge-Prostate cancer palliation: Umthamo uvamise ukuba ngu-1 kuye ku-2 mg ngomlomo kathathu ngosuku noma ama-30 mg imijovo ye-intramuscular njalo emavikini angu-1-2. 

Isiphetho

Indima ye-Oestrogen emizimbeni yethu idlulela ngalé kwempilo yokuzala, ibe nomthelela omkhulu ezicini ezihlukahlukene zenhlalakahle yethu. Kusukela ekulawuleni ukuminyana kwamathambo kuya kusimo sengqondo esithonyayo, le hormone enamandla ibumba izici zomzimba kanye nemisebenzi ebalulekile yomzimba kubo bobabili abesilisa nabesifazane. Ukuqonda ukubaluleka kwe-estrogen kusisiza ukuba sazise imiphumela yayo empilweni yonke kanye nezinzuzo ezingaba khona zokwelashwa okusekelwe ku-estrogen ezimweni ezihlukahlukene zezokwelapha.

Kodwa-ke, kubalulekile ukukhumbula ukuthi lezi zindlela zokwelapha kufanele zisetshenziswe njalo ngaphansi kokuqondisa kukadokotela. Ngokugcina amazinga e-estrogen afanelekile futhi siqaphela ukungalingani okungenzeka, singathatha izinyathelo zokusekela impilo yethu nokuphila kahle ezigabeni ezihlukahlukene zokuphila.

FAQ sika

1. I-estrogen yenzani kowesifazane?

I-Estrogen idlala indima ebalulekile empilweni yokuzala yabesifazane kanye nenhlalakahle jikelele. Ilawula i- umjikelezo wokuya esikhathini, isekela ukukhula kwebele, futhi igcine impilo yesitho sangasese sowesifazane. Le hormone iphinde ithinte ukuminyana kwamathambo, impilo yenhliziyo, nokusebenza kobuchopho. I-Estrogen isiza ukuvikela ngokumelene ne-osteoporosis, ilawula amazinga e-cholesterol, futhi ithuthukise ukusimama kwemizwelo. Ngesikhathi sokunqamuka kokuya esikhathini, lapho amazinga e-estrogen ehla, abesifazane bangase babe nezimpawu ezinjengokoma kwesitho sangasese sowesifazane, ukushisa okushisayo, nokushintsha kwemizwa.

2. Enzani amaphilisi e-estrogen?

Amaphilisi e-Estrogen awuhlobo lwe-hormone replacement therapy (HRT) esetshenziselwa ukubhekana nezimpawu zokunqamuka kokuya esikhathini kanye nezinye izimo ezihlobene namazinga aphansi e-estrogen. Basiza ekwehliseni ukushisa, ukomisa kwesitho sangasese sowesifazane, kanye nokuya ocansini okubuhlungu. Amaphilisi e-Estrogen nawo angavimbela ukulahleka kwamathambo futhi anciphise ingozi ye-osteoporosis kwabesifazane abangemva kokuya esikhathini. Amanye amafomu ahlanganisa i-estrogen ne-progestin ukunciphisa ingozi umdlavuza wesibeletho kwabesifazane abasenezibeletho zabo.

3. Yiziphi izinzuzo zokuthatha amaphilisi e-estrogen?

Ukuphuza amaphilisi e-estrogen kunganikeza impumuzo ezimpawini zokunqamuka kokuya esikhathini njengokushisa okushisayo nokungakhululeki kwesitho sangasese sowesifazane. Basiza ukugcina ukuminyana kwamathambo, ukunciphisa ingozi ye-osteoporosis. Ukwelashwa nge-Estrogen kungase futhi kube nomthelela omuhle empilweni yenhliziyo ngokuthuthukisa amazinga e-cholesterol kanye nokuzinzisa umfutho wegazi. Abanye besifazane babika isimo esithuthukisiwe nokusebenza kwengqondo lapho bethatha amaphilisi e-estrogen. Ukwengeza, i-estrogen ingasiza ekulondolozeni ukunwebeka kwesikhumba futhi ikhuthaze ikhwalithi yokulala engcono.

4. Ingabe kuphephile ukuthi ngiphuze amaphilisi e-estrogen?

Ukuphepha kokuthatha amaphilisi e-estrogen kuncike ezicini zezempilo zomuntu ngamunye futhi kufanele kuxoxwe nodokotela. Nakuba ukwelashwa kwe-estrogen kunganikeza izinzuzo, kuphinde kube nezingozi ezingase zibe khona, kuhlanganise nethuba elikhulayo loku unhlangothi, ikhanda elibuhlungu, amahlule egazi, nezinhlobo ezithile zomdlavuza. Ubungozi bungase buhluke ngokusekelwe kumthamo nesikhathi sokusetshenziswa. Abesifazane abanomlando womdlavuza othile, isifo sesibindi, noma amahlule egazi kufanele bagweme ukwelashwa kwe-estrogen.