I-Omeprazole

I-Omeprazole

I-Omeprazole ingeyesigaba semithi ebizwa ngokuthi i-proton pump inhibitors kanye kunciphisa ukukhiqizwa kwe-asidi esiswini. Lo muthi ngezikhathi ezithile usetshenziswa kanye nemithi yokwelapha izilonda ezixhumene nesifo esilethwa i-H. pylori bacterium.

Yiziphi izinzuzo ze-Omeprazole?

I-Omeprazole yehlisa ukukhishwa kwe-asidi esiswini, okuyenza iphumelele ekwelapheni izinkinga ezimbalwa zesisu kanye ne-esophageal. Isilungulela, izinkinga zokugwinya, kanye ukukhwehlela bonke bayasuswa ngakho. Lo muthi ungasiza ekuvimbeleni umdlavuza womphimbo futhi usize ekwelapheni ukulimala kwe-asidi esiswini kanye nomminzo. Kuyasiza nokugwema izilonda. Sekukonke, i-Omeprazole isetshenziselwa ukwelapha i-asidi yesisu eyeqile ezinkingeni ezifana nezilonda zesisu ezingenawo umdlavuza, izilonda ezisebenzayo ze-duodenal, i-Gastroesophageal Reflux Disease (GERD), i-Zollinger-Ellison syndrome, i-Erosive esophagitis. 

Umuthi

I-Omeprazole inqunyelwe izimo ezilandelayo zabantu abadala:

• Izilonda zesisu

• Izilonda ze-Duodenal

• Ukutheleleka kwe-Helicobacter pylori (H. pylori) ngaphakathi kwesistimu yokugaya ukudla

• Isifo se-Gastro-esophageal Reflux (GERD)

• I-Esophagitis ebangelwa i-GERD

• I-Zollinger-Ellison syndrome.

Ngiyithatha kanjani futhi nini i-Omeprazole?  

• I-Omeprazole kufanele ithathwe ngendlela enconywe ngayo kulebula noma udokotela wakho. Funda noma yimiphi imiyalelo yomuthi noma amaphepha eziqondiso futhi ubambelele kuzo zonke iziqondiso ezikulebula yakho kadokotela.
• Sebenzisa izandla ezomile ukuze uthinte amaphilisi ancibilikayo ukuze ubambezele ukukhishwa uma uwasebenzisa. Faka ithebhulethi olimini lwakho, bese ulinda ukuthi incibilike. Kuyenzeka ukugwinye iphilisi ngamanzi noma ngaphandle kwawo uma selibhodlokile. 
• Umthamo kufanele ulinganiswe ngemuva kokunyakazisa isisombululo somlomo (uketshezi). Sebenzisa ithuluzi lokulinganisa umthamo noma isirinji yomthamo enikezwe nomuthi.
• Kuyadingeka ukuxuba amanzi kancane ne-Omeprazole powder ngaphambi kokusetshenziswa. Ngokusebenzisa isirinji enesihloko se-catheter, le nhlanganisela ingangenwa noma iphathwe ngeshubhu yokudla ye-Nasogastric (NG).
• I-Omeprazole OTC kufanele isetshenziswe kuphela izinsuku eziyi-14 zilandelana. Ngaphambi kokuqala uhlelo olusha lwezinsuku eziyi-14, linda okungenani izinyanga ezi-4.
• Umthamo wezingane nawo unqunywa isisindo. Ungalokothi usebenzise lo muthi ngamanani amakhulu noma kaningi kunalokho okunconyiwe.
• Ama-antacid anganikezwa ngaphezu kwalo muthi uma kunesidingo. I-Omeprazole kufanele iphuzwe okungenani imizuzu engama-30 ngaphambi kwe-sucralfate uma uyithatha.

Iyini imiphumela emibi ye-Omeprazole?

Uma unanoma yiziphi izimpawu ezishiwo zokungezwani komzimba ne-Omeprazole, okuhlanganisa ukuphefumula kanzima noma ukuvuvukala kobuso bakho, ulimi, izindebe, noma umphimbo, thola usizo lwezempilo oluphuthumayo. Uma uhlangabezana nanoma iyiphi yalezi zinkinga ezilandelayo, yeka ukusebenzisa lo muthi futhi ubone udokotela wakho:  

• Ubuhlungu obusha noma obungajwayelekile esihlakaleni sakho, ethangeni, okhalweni, noma emhlane
• Izimpawu ezibandayo zihlanganisa ikhala eligelezayo, ukuthimula, kanye a umphimbo obuhlungu
• Igazi emchameni, ukuchama okuvamile noma okungajwayelekile, ubuhlungu bamalunga, isicanucanu, noma ukuphelelwa ukudla
• Ubuhlungu besisu obukhulu, imfiva engapheli, indle enamanzi, nesifo sohudo
• Isikhumba esinamabhamuza, ama-flakes, noma ukopha; izilonda zesitho sangasese sowesifazane, udebe, ikhala, umlomo, noma umphimbo; izindlala ezikhulisiwe; ubunzima bokuphefumula; imfiva; noma izimpawu ezinjengomkhuhlane.
• Ukukhathala okukhulu, ukugijima noma ukushaya kwenhliziyo, ukuqhaqhazela okuzenzakalelayo kwelungu lomzimba, imisipha, ukudideka, noma ukudlikizeka
• Ama-polyps e-Fundic gland, okuwukukhula kwesisu, angakheka uma uthatha i-Omeprazole isikhathi eside. 

Xhumana nodokotela wakho mayelana nalezi zingozi. Ungase ube ne-vitamin B-12 entula uma usebenzisa le mithi iminyaka engaphezu kwemithathu.

Yini okufanele ngiyenze uma ngiphuthelwa umthamo we-Omeprazole?

Thatha umthamo ogejiwe ngokushesha nje lapho usuwukhumbula. Uma isikhathi somthamo olandelayo sisondela, gwema umthamo ogejiwe. Thatha umthamo wakho olandelayo ngesikhathi esijwayelekile.

Yini okufanele ngiyenze uma ngidlula i-Omeprazole?

Kunoma ikuphi, uma uphuze umthamo owengeziwe we-Omeprazole, thintana nodokotela wakho ngokushesha noma uvakashele isibhedlela esiseduze. Kunconywa ngokuqinile ukuthi ungathathi i-overdose, futhi ugcine kuphela imithamo yakho emikhawulweni njengoba kunqunywe udokotela.

Yimiphi imithi i-Omeprazole engase ihlangane nayo?

Ukusebenzisa imithi embalwa ngesikhathi esisodwa akwelulekwa. Eminye imithi oyiphuzayo ingase ibe nemiphumela emibi eyengeziwe noma ilahlekelwe ukusebenza kwayo uma imithi ethile inomthelela emazingeni egazi aleyo mithi.    

• Digoxin
• I-Methotrexate
• I-Clopidogrel
• I-diuretic noma "iphilisi lamanzi"
• I-antibiotic - i-amoxicillin, i-clarithromycin

Yonke imithi yakho ekhona kufanele kushiwo kudokotela wakho ukuze uthole enye incwadi ephephile.

Yiziphi izinyathelo zokuqapha lapho uthatha i-Omeprazole?    

• Uma usebenzisa i-Omeprazole, yazisa udokotela wakho noma usokhemisi nganoma yikuphi okunye ukungezwani komzimba okungenzeka ube nakho, kanye nanoma yikuphi ukungezwani nakho kuyo noma eminye imithi ehlobene nayo. Lo mkhiqizo ungase uhlanganise amakhemikhali angasebenzi angase aholele ekungezwani komzimba noma ezinye izinkinga.
• Ngaphambi kokusebenzisa le mithi, thintana nodokotela wakho noma usokhemisi mayelana nomlando wakho wezokwelapha, ikakhulukazi noma yikuphi ukugula kwesibindi noma i-lupus.
• Sebenzisa lo muthi kuphela uma unqunywe udokotela ngenkathi ukhulelwe. Izinzuzo nezingozi kufanele kuxoxwe ngazo nodokotela wakho.
• I-Proton pump inhibitors ingaphakamisa ingozi yakho yokuphuka kwamathambo, ikakhulukazi uma uwasebenzisa isikhathi eside, uthatha imithamo emikhulu, noma usukhulile. Khuluma nodokotela wakho mayelana nokuthatha izithako ze-calcium ne-vitamin D ukuvimbela ukulahlekelwa kwamathambo nokuphuka.

Ungagcina futhi ulahle kanjani i-Omeprazole? 

• Gcina lo muthi ungekude nezingane zakho futhi uvalwe ngokuqinile esitsheni. Kude nokukhanya, ukushisa okukhulu, kanye nomswakama, kugcine endaweni yokugcina izinga lokushisa.
• Umuthi ongasadingeki noma ophelelwe yisikhathi akufanele ugcinwe.
• Ukuze ulahle noma yimuphi umuthi ongawusebenzisi, bheka ilebula noma ubuze uchwepheshe wezokwelapha ngawo.

I-Omeprazole isebenza isikhathi esingakanani?

Umphumela ogcwele we-Omeprazole uzwakala cishe amahora amabili ngemva kokuphuza umuthi, futhi kuthatha cishe ihora ukumisa ukukhiqizwa kwe-asidi esiswini.

I-Omeprazole vs Pantoprazole

Imibuzo Evame Ukubuzwa

1. Ingabe i-omeprazole idala ukushoda kwamavithamini?

Ukusetshenziswa isikhathi eside kwe-omeprazole kunganciphisa ukumuncwa kwamavithamini athile afana ne-B12 ne-magnesium. Kutuswa ukuthi abasebenzisi besikhathi eside baqaphe amazinga abo kavithamini futhi bacabangele ukwengezelelwa uma kunesidingo.

2. Ingabe iziguli zenhliziyo zingayithatha i-omeprazole?

I-Omeprazole ngokuvamile iphephile ezigulini eziningi zenhliziyo. Kodwa-ke, kubalulekile ukuthi iziguli ezinezimo zenhliziyo zixoxe ngokusetshenziswa kwayo nomhlinzeki wezempilo, njengoba ingasebenzisana nemithi ethile yenhliziyo.

3. Iyini imiphumela emibi ye-Omeprazole yesikhathi eside?

Ukusetshenziswa isikhathi eside kwe-omeprazole kuye kwahlotshaniswa nemiphumela engemihle engaba khona, okuhlanganisa ingozi eyengeziwe yokuphuka kwamathambo, izinkinga zezinso, kanye nokutheleleka kweClostridium difficile. Ukuqapha njalo nezingxoxo nomhlinzeki wezokunakekelwa kwempilo kuhle kulabo abathola ukwelashwa kwesikhathi eside.

4. Yini okufanele ngiyiqaphele ngaphambi kokusebenzisa i-Omeprazole?

Ngaphambi kokusebenzisa i-omeprazole, yazisa umhlinzeki wakho wokunakekelwa kwezempilo nganoma ikuphi ukungezwani komzimba, izimo zezokwelapha ezikhona, kanye nemithi oyiphuzayo. Qaphela ukusebenzisana kwezidakamizwa okungenzeka futhi ulandele umthamo onqunyiwe kanye nobude besikhathi. Izinguquko zendlela yokuphila, njengokushintsha ukudla, nazo zinganconywa.

5. Ingabe kuphephile ukuhlanganisa i-omeprazole ne-domperidone?

I-Omeprazole ne-domperidone zinganqunywa ndawonye kwezinye izimo. I-Omeprazole yehlisa ukukhiqizwa kwe-asidi esiswini, kuyilapho i-domperidone isiza nge-gastric motility. Nokho, ukusetshenziswa kwabo okuhlangene kufanele kube ngaphansi kokuqondisa kwezokwelapha, futhi isinqumo sincike esimweni esithile sesiguli kanye nezidingo. Xoxa ngalokhu nomhlinzeki wakho wokunakekelwa kwezempilo.

References:

https://www.webmd.com/drugs/2/drug-3766-2250/Omeprazole-oral/Omeprazole-delayed-release-tablet-oral/details https://medlineplus.gov/druginfo/meds/a693050.html#:~:text=Nonprescription%20(over%2Dthe%2Dcounter,acid%20made%20in%20the%20stomach.

Umshwana wokuzihlangula: Ulwazi olunikezwe lapha alwenzelwe ukufaka iseluleko esivela kuchwepheshe wezokunakekelwa kwempilo. Ulwazi aluhloselwe ukumboza konke ukusetshenziswa okungenzeka, imiphumela engemihle, izinyathelo zokuphepha, nokusebenzisana kwezidakamizwa. Lolu lwazi aluhloselwe ukuphakamisa ukuthi ukusebenzisa umuthi othile kufanelekile, kuphephile, noma kuyasebenza wena noma omunye umuntu. Ukungabi bikho kwanoma yiluphi ulwazi noma isexwayiso mayelana nomuthi akufanele kuhunyushwe njengesiqinisekiso esicacile esivela enhlanganweni. Sikweluleka ngokuqinile ukuthi uthintane nodokotela uma kukhona okukukhathazayo ngomuthi futhi ungalokothi usebenzise umuthi ngaphandle kwencwadi kadokotela.