I-Prednisolone

I-Prednisolone

I-Prednisolone, i-corticosteroid enamandla, idlala indima ebalulekile ekwelapheni izindaba ezihlukene zezempilo, kusukela kokungaphatheki kahle komzimba nezinto ezithile kuya ezifweni ze-autoimmune. Lo muthi oguquguqukayo unciphisa ukuvuvukala futhi ucindezele amasosha omzimba, ukhulula iziguli eziningi ezibhekene nezifo ezingamahlalakhona.
Kulesi sihloko, sizohlola ukungena nokuphuma kwe-prednisolone, okuhlanganisa ukusetshenziswa kwayo, umthamo, kanye nemiphumela engemihle engaba khona.

Iyini i-Prednisolone?

I-Prednisolone umuthi onamandla we-corticosteroid odokotela abawunikeza ukwelapha izinkinga eziningi zempilo. Lesi sidakamizwa esikhiqizwayo silingisa ihomoni yemvelo ye-corticosteroid ekhiqizwa indlala ye-adrenal. Odokotela basebenzisa i-prednisolone ukuphatha izimo ezifana nokungezwani komzimba nezinto ezithile, ukuphazamiseka kwegazi, izifo zesikhumba, ukuvuvukala, izifo kanye nomdlavuza othile. Kuyasiza futhi ukuvimbela ukwenqatshwa kwesitho ngemva kokufakelwa.

Ukusetshenziswa kwe-Prednisolone

I-Prednisolone, umuthi onamandla we-corticosteroid, welapha izifo eziningi, njenge: 

• Asthma
• Ukuphendula kwe-allergen
• Isifo Sokuqaqamba Kwamalunga 
• Izifo zamathumbu ezivuthayo
• Ukuphazamiseka kwe-adrenal
• Igazi noma umkantsha izinkinga 
• Ukuphazamiseka kwesistimu yomzimba
• Izimo zesikhumba nezamehlo
• Umdlavuza othile
• I-allergies enzima
• Vimbela ukwenqatshwa kwesitho ngemuva kokufakelwa, njengoba i-prednisolone icindezela amasosha omzimba. 

Odokotela bangase banikeze i-prednisolone ngezinye izinjongo ezingashiwongo lapha. Iziguli kufanele zihlale zithintana nodokotela wazo uma zinemibuzo mayelana nokusetshenziswa kwayo.

Ungayisebenzisa kanjani i-Prednisolone Tablet

Odokotela banquma i-prednisolone ngeziqondiso ezithile. 

• Ukuze ugweme ukucasuka kwesisu, iziguli kufanele ziwuthathe ngokudla noma ubisi.  
• Ngokuvamile, odokotela bayeluleka ukuthatha i-prednisolone njengomthamo owodwa ekuseni kanye nesidlo sasekuseni. Lesi sikhathi sisiza ukuvimbela ukuphazamiseka kwesisu nokuphazamiseka kokulala.
• Kumaphilisi ane-enteric-coated noma amelana ne-gastro, iziguli kufanele ziwagwinye ewonke, kugwenywe imishanguzo yokugaya ukudla amahora amabili ngaphambi noma ngemva kwalokho. Abanye odokotela bangase batusa ukuthatha i-prednisolone ngezinye izinsuku.
• Uma weqiwe umthamo, yithathe ngokushesha nje lapho ukhumbula khona ngaphandle uma sekusondele isikhathi somthamo olandelayo. Uma kunjalo, kufanele weqe umthamo ogejiwe futhi uqhubeke neshejuli evamile.

Imiphumela Emibi Yethebhulethi ye-Prednisolone

I-Prednisolone ingabangela imiphumela engemihle ehlukahlukene, kusukela komnene kuye konzima. Imiphumela emibi evamile ye-prednisolone ihlanganisa: 

• Ukwandisa ukudla 
• Inzuzo yesisindo 
• Inkinga yokulala 
• induna
• Ukuphathwa yikhanda 
• Ukungakhululeki okuvamile

Le miphumela ngokuvamile ayidingi ukunakwa ngokushesha, kodwa kufanele uyibike uma iphikelela noma ihlupha.
Okuningi mayelana nemiphumela emibi ye-prednisolone ihlanganisa: 

• Ukuphendula kwe-allergen
• Izimpawu ze-Cushing's syndrome
• Ushukela ophakeme wegazi
• Ukwanda kwengcindezi yegazi 
• Imodi iyashintsha
• Ukwanda kokungenwa yizifo
• Iziguli kufanele zibheke izimpawu ezinjengokuqubuka kwesikhumba, ukukhuluphala okungajwayelekile, ukoma okwandayo, noma imizwa yokukhathazeka noma ukucindezeleka.
• Ukusetshenziswa isikhathi eside kwamaphilisi e-prednisolone kungaholela ekukhathazekeni okwengeziwe okufana namathambo amancane, angalawulwa kahle. sikashukela, nezinkinga zamehlo. 
• Izingane ezithatha i-prednisolone zingase zithole ukukhula kancane, okudinga ukuqashwa ngokucophelela ngudokotela wazo.

Ukuqapha

Iziguli ezithatha i-prednisolone zidinga ukuqapha, okuhlanganisa: 

• Ukuqapha: Ukuqokwa njalo nokuhlolwa nodokotela kubalulekile ukuze kuqashwe ukusebenza komuthi nokunquma ukuthi kuyadingeka yini ukuqhubeka nokusetshenziswa. Ukuhlolwa kwegazi noma umchamo kungase kudingeke ukuze kuhlolwe imiphumela engadingeki. 
• Izimo Zezokwelapha: Abantu abanezinkinga ezithile zesistimu, njengezifo zenhliziyo, i-glaucoma, ulwelwesi lwamehlo, umfutho wegazi ophakeme, izinkinga zesibindi, ukwehluleka kwezinso, izilonda zesisu, ukuphazamiseka kwegilo, amathambo aphukayo, isifo sofuba, ukuphazamiseka kwegazi, ukuhlukunyezwa, kanye nezimila ezithile ze-adrenal gland, thintana nomlando wabo wezokwelapha ngaphambi kokuqala lo muthi.
• Qaphela Izimpawu Eziwohlozayo: Ukusetshenziswa isikhathi eside noma imithamo eyeqile kungandisa ingozi yezinkinga ze-adrenal gland. Iziguli kufanele zibike izimpawu ezifana nokuba mnyama kwesikhumba, isiyezi, noma ukukhathala okungajwayelekile kudokotela wazo ngokushesha.
• Izinguquko Zengqondo/Zemizwelo: Iziguli kufanele zazise udokotela wazo uma zithola ukucindezeleka, ukushintsha kwemizwa, noma ukuphazamiseka kokulala.
• Ukuqapha Utshwala: Gwema utshwala ngenkathi uthatha i-prednisolone, njengoba zombili zingacindezela amasosha omzimba, okwandisa ingozi yokutheleleka.

Isebenza kanjani ithebhulethi ye-Prednisolone

I-Prednisolone iyi-corticosteroid engena kumaseli futhi ibophezele kuma-receptors e-glucocorticoid. Le nkimbinkimbi ithuthela ku-nucleus yeseli, ithonya ukwakheka kofuzo. I-Prednisolone inciphisa ukukhiqizwa kwamakhemikhali avuthayo futhi icindezela umsebenzi wamasosha omzimba. Kuthinta izinqubo ezihlukahlukene zomzimba, ukusiza izimo ezifana nesifuba somoya, ukuvuvukala kwesikhumba, kanye nezifo ezizimele. Umuthi unomthelela kumetabolism, okungenzeka ukuthi uthinte amazinga kashukela egazini. I-prednisolone yomlomo ngokuvamile iqala ukusebenza phakathi namahora, ibe nemiphumela ehlala usuku.

Ngingathatha I-Prednisolone Neminye Imithi?

Ithebhulethi ye-Prednisolone dispersible isebenzisana nemithi eminingi, okwenza kube semqoka ukubonana nodokotela ngaphambi kokuyihlanganisa nezinye izidakamizwa. Imithi evamile engase ihlanganyele ne-prednisolone ihlanganisa: 

• aspirin
• I-Azathioprine
• Izidakamizwa ze-Azole
• I-Celecoxib
• Clarithromycin
• I-Clopidogrel
• Desmopressin
• Ibuprofen
• I-Mifepristone
• Phenytoin
• Rifampin 
• Warfarin
• Kubalulekile futhi ukugwema ukuhlanganisa i-prednisolone nemigomo ephilayo, njengoba lokhu kungase kuphazamise ukusebenza kwayo kahle. 

Ulwazi Lomthamo

Odokotela bathungela umthamo we-prednisolone ngokwezidingo zesiguli ngasinye. 
Kubantu abadala, umthamo wokuqala usukela ku-5 kuye ku-60 mg nsuku zonke. 
Imithamo yezingane incike esisindweni somzimba, ngokuvamile i-0.14 kuya ku-2 mg ngekhilogremu ngayinye nsuku zonke, ihlukaniswe ngemithamo emi-3 noma emi-4.

Isiphetho

I-Prednisolone inethonya elikhulu ekulawuleni izimo zezempilo eziningi. Amandla ayo okunciphisa ukuvuvukala futhi acindezele amasosha omzimba ayenza ibe ithuluzi elibalulekile lokwelapha i-allergies, ukuphazamiseka kwe-autoimmune, nezinye izifo. Lo muthi oguquguqukayo unikeza impumuzo ezigulini eziningi ezibhekene nezinkinga zempilo ezingamahlalakhona, zithuthukisa izinga lempilo yazo.

Ama-FAQ:

1. I-prednisolone isetshenziselwa ini ngokuyinhloko?

Odokotela bayinikeza i-allergies, ukuphazamiseka kwegazi, izifo zesikhumba, ukuvuvukala, izifo kanye nomdlavuza othile. Iphinde ivimbele ukwenqatshwa kwesitho ngemuva kokufakelwa. Umuthi unciphisa ukuvuvukala futhi wehlise amasosha omzimba, usize ezimweni ezingamahlalakhona ezifana rheumatoid arthritis.

2. Ubani okufanele aphuze i-prednisolone?

Abantu abanezimo ze-autoimmune, njenge-rheumatoid arthritis, bavame ukudinga i-prednisolone. Iphinde isize labo abanesifo samathumbu avuvukalayo, isifuba somoya, kanye nokungezwani komzimba nomzimba kakhulu. Iziguli ezinezimo ezithile ze-endocrine, njenge-congenital adrenal hyperplasia, zingayidinga. Ezinye izimo zesikhumba, kufaka phakathi ezinzima psoriasis kanye nesifo sikaStevens-Johnson, nabo bayazuza ekwelashweni kwe-prednisolone.

3. Ingabe kubi ukusebenzisa i-prednisolone nsuku zonke?

Ukusetshenziswa kwansuku zonke kwe-prednisolone kungaholela emiphumeleni emibi, ikakhulukazi kumithamo ephezulu noma isikhathi eside. Iziguli kufanele zilandele imiyalelo kadokotela wazo ngokucophelela futhi zixoxe nganoma yikuphi ukukhathazeka mayelana nokusetshenziswa isikhathi eside.

4. Ingabe i-prednisolone iphephile?

I-Prednisolone ngokuvamile iphephile uma isetshenziswa njengoba kushiwo. Nokho, kungabangela imiphumela engemihle, ikakhulukazi ngokusetshenziswa isikhathi eside. Lokhu kungase kuhlanganise ukuncipha kwamathambo, isifo sikashukela esingalawuleki kahle, nezinkinga zamehlo. 

5. Ubani Ongakwazi ukusebenzisa i-prednisolone?

Abantu abanezimo ezithile kufanele bagweme i-prednisolone noma bayisebenzise ngokuqapha. Lezi zihlanganisa labo abanezinkinga zesibindi, ukuhluleka kwenhliziyo, umfutho wegazi ophakeme, isifo sikashukela, noma i-glaucoma. Abesifazane abakhulelwe noma abancelisayo kufanele babonane nodokotela wabo ngaphambi kokuthatha i-prednisolone. Labo abanezifo zamanje noma abanomlando wofuba kufanele bazise udokotela wabo.

6. Ngingakwazi ukuthatha i-prednisolone ebusuku?

Ukuthatha i-prednisolone ebusuku kungabangela ukuphazamiseka kokulala. Odokotela ngokuvamile batusa ukuthi uyiphuze ekuseni ngesidlo sasekuseni. 

7. Yisiphi isikhathi esingcono kakhulu sokuthatha i-prednisolone?

Isikhathi esingcono kakhulu sokuthatha i-prednisolone imvamisa ekuseni ngesidlo sasekuseni. Lesi sikhathi sihambisana nenani eliphakeme lokukhiqizwa kwe-cortisol yomzimba (2 kuya ku-8 AM). Ukuyithatha nokudla kusiza ekunciphiseni ukucasuka kwesisu. Kulabo abathola ukwelashwa kolunye usuku, landela uhlelo olunikezwe udokotela wakho.

8. Yini okufanele uyigweme lapho uthatha i-prednisolone?

Ngenkathi uthatha i-prednisolone, gwema ukuyeka umuthi kungazelelwe ngaphandle kweseluleko sezokwelapha. Nciphisa ukuphuza utshwala, njengoba kungase kwandise ingozi yokopha esiswini. Qaphela ngemithi yokugoma ephilayo futhi wazise udokotela wakho ngaphambi kokuthola noma yimiphi imigomo. Gwema ukudla okucebile noma okubabayo ukuze unciphise izinkinga zesisu. Okokugcina, khumbula ukudla kwakho kwe-sodium futhi ucabange ukwandisa ukudla kwakho kwe-calcium ne-vitamin D ukuze usekele impilo yamathambo.