I-Prochlorperazine

I-Prochlorperazine

I-nausea futhi isiyezi ingaba nomthelela omkhulu empilweni yansuku zonke, ikwenze kube lula ukwenza imisebenzi eyinselele. I-Prochlorperazine ime njengomunye wemithi evame ukunikezwa ukusiza abantu ukuphatha lezi zimpawu ezingakhululekile ngempumelelo. Lo mhlahlandlela obanzi uchaza yonke into iziguli okudingeka ziyazi ngomuthi we-prochlorperazine - kusukela ekusetshenzisweni kwawo nasekuphathweni ngendlela efanele kuya emiphumeleni engemihle engaba khona kanye nezinyathelo zokuphepha ezifanele. 

Iyini iProchlorperazine?

I-Prochlorperazine imithi enamandla eyingxenye yezidakamizwa ezibizwa ngokuthi i-conventional antipsychotics. 

Lo muthi oguquguqukayo unciphisa injabulo engavamile ebuchosheni futhi uvimbele okuqondile i-dopamine ama-receptors. Umsebenzi wawo oyinhloko uhilela ukulawula indawo yokuqalisa i-chemoreceptor yomzimba, edlala indima ebalulekile ekulawuleni isicanucanu nezinye izimpawu.

Ukusetshenziswa kwethebulethi yeProchlorperazine

Ukusetshenziswa okuyinhloko kwethebhulethi ye-prochlorperazine kuhlanganisa:

• Ukwelashwa kwesicanucanu nokuhlanza
• Ukulawulwa kwezimpawu ze-schizophrenia
• Ukulawula ukukhathazeka okungezona ezengqondo
• Ukwelashwa okuphuthumayo kwe-migraines kokubili abadala kanye nezingane

Isetshenziswa kanjani i-Prochlorperazine Tablet

• Ukuthatha amaphilisi e-prochlorperazine ngendlela efanele kuqinisekisa imiphumela engcono kakhulu etholakala emuthini. Amaphilisi eza ngezinhlobo ezimbili: amaphilisi ajwayelekile iziguli eziwagwinya egcwele amanzi kanye namaphilisi e-buccal ancibilika phakathi kodebe olungaphezulu noshingamu.
• Ukuze kusebenze kahle kakhulu, iziguli kufanele zithathe imithamo yazo ngesikhathi esifanayo usuku ngalunye. Uhlelo lwemithi ngokuvamile lubandakanya ukuphuza amaphilisi izikhathi ezintathu kuya kwezine ngosuku kubantu abadala, kuyilapho izingane ngokuvamile zithola umthamo owodwa kuya kwemithathu ngosuku.
• Gcina amaphilisi ekamelweni lokushisa {68°F kuya ku-77°F (20°C kuya ku-25°C)}
• Gcina endaweni epholile, eyomile esitsheni esikwazi ukumelana nokukhanya
• Iziguli akufanele neze ziyeke ukuthatha i-prochlorperazine kungazelelwe ngaphandle kokubonana nodokotela wazo, njengoba lokhu kungase kubangele izimpawu zokuhoxa njengesicanucanu, isiyezi, noma ukuqhaqhazela. 
• Uma umthamo weqiwe, wuthathe ngokushesha njengoba ukhunjulwa ngaphandle kwalapho sekusondele isikhathi somthamo olandelayo ohleliwe.

Imiphumela Emibi Yethebhulethi ye-Prochlorperazine

Amaphilisi e-Prochlorperazine angabangela imiphumela engemihle, nakuba kungebona bonke abahlangabezana nayo. 

Imiphumela Emibi Evamile:

• Ukuzizwa ukozela noma ukozela
• Umlomo omile
• Umbono ophundlekile
• Ukusabela kwesikhumba okuthambile
• ukuqunjelwa
• Kunzima ukulala
• Ukuphumula

Iziguli kufanele zifune usizo kodokotela bazo ngokushesha uma zibona:

• Umkhuhlane ophezulu nge ukuqina kwemisipha
• Ukusuka okungavamile noma ukulimaza
• Ukuphuzi kwesikhumba noma amehlo
• ezinzima ubuhlungu besisu
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Ukuphefumula kanzima

Ukuqapha

Ngaphambi kokuqala ukwelashwa kwe-prochlorperazine, iziguli kufanele ziqonde izinto ezimbalwa ezibalulekile zokuphepha. 

• Izimo Zezokwelapha Ezibalulekile Okufanele Zicatshangelwe:
  • I-glaucoma noma izinkinga zokubona
  • Isifo senhliziyo noma ukushaya kwenhliziyo okungajwayelekile
  • Isifo sesibindi
  • Seizure ukuphazamiseka
  • I-Prostate izinkinga
  • Umlando wokuphazamiseka kwegazi
  • Ukulimala kwengqondo noma ukulimala ekhanda
• Izingane: Izingane ezingaphansi kweminyaka engu-2 ubudala noma ezinesisindo esingaphansi kuka-9 kg akufanele ziphuze lo muthi
• Ukuqwashisa Okuncishisiwe: Gwema ukushayela uze wazi ukuthi umuthi ukuthinta kanjani ukuqapha
• Gwema Ukuchayeka Elangeni: Sebenzisa isivikelo elangeni njengoba umuthi ungandisa ukuzwela kwesikhumba.

Isebenza kanjani ithebhulethi yeProchlorperazine

Isayensi esebenza ngempumelelo ye-prochlorperazine ilele ekusebenzelaneni kwayo okuyingqayizivele nezithunywa zamakhemikhali zobuchopho. Le mithi ingeyeqembu elibizwa ngokuthi i-conventional antipsychotics futhi isebenza ngokunciphisa ukujabula okungavamile ebuchosheni.

Izenzo ezibalulekile emzimbeni:

• Ivimbela ama-dopamine receptors ukulawula isicanucanu
• Yehlisa ukujabula kobuchopho okungavamile
• Ithinta izinhlobo eziningi zama-receptor, okuhlanganisa i-histamine ne-acetylcholine
• Ilawula ukunyakaza kwe-calcium ion kumaseli

Ngingathatha I-Prochlorperazine Neminye Imithi?

Ukusebenzisana kwemithi kudinga ukunakwa ngokucophelela lapho uthatha i-prochlorperazine.  

Izinhlobo zemithi ebalulekile okufanele zibukwe:

• Umuthi we-Anticholinergic
• Umuthi we-antiseizure
• Izidakamizwa ezibangela umlomo owomile
• Imithi yenhliziyo
• Lithium
• Imithi ebangela ukozela (imithi yezinhlungu, imithi yokulala, nemithi yokukhathazeka)
• Eminye imithi yokulwa nokugula

Ulwazi Lomthamo

Kubantu abadala ababhekene nokucanuzela kwenhliziyo okukhulu nokuhlanza, uhlelo olujwayelekile lokudosa luhlanganisa:

• I-5 noma i-10 mg ithathwa izikhathi ezi-3 kuya kwezi-4 ngosuku
• Umthamo omkhulu wansuku zonke akufanele ube ngaphezu kwama-40 mg
• Ukwelashwa kokukhathazeka, imithamo ikhawulelwe ku-20 mg ngosuku kuze kube amasonto ayi-12

Ukucatshangelwa Okukhethekile Kwabantu: Umuthi udinga ukulungiswa ngokucophelela kwemithamo emaqenjini athile. Imithamo yezingane ibalwa ngokuya ngesisindo sazo:

• 9-13 kg: 2.5 mg kanye noma kabili ngosuku (esiphezulu 7.5 mg / ngosuku)
• 13-18 kg: 2.5 mg izikhathi ezimbili noma ezintathu ngosuku (esiphezulu 10 mg / ngosuku)
• 18-39 kg: Kuphakathi kokuthi 2.5 mg kathathu ngosuku noma i-prochlorperazine 5mg kabili ngosuku

Isiphetho

I-Prochlorperazine imele njengomuthi othembekile wokwelapha izimo ezihlukahlukene, kusukela ekucanuzeleni kwenhliziyo kuye kokukhathazeka kanye ne-schizophrenia. Odokotela bathembele kulo muthi oguquguqukayo amashumi eminyaka ngenxa yokusebenza kwawo okuqinisekisiwe nezindlela eziqondwa kahle.

Iziguli ezithatha i-prochlorperazine zidinga ukunakwa ngokucophelela kumashejuli womthamo, imiphumela emibi engaba khona, nokusebenzisana kwezidakamizwa. Ukuphumelela ngalo muthi kuncike ekulandeleni imiyalelo kadokotela eduze, ukugcina ukuhlolwa okuvamile, nokubika noma yiziphi izimpawu ezingavamile ngokushesha.

Ukusetshenziswa okuphephile kwe-prochlorperazine kudinga ukuqonda kokubili izinzuzo zayo kanye nemikhawulo. Nakuba imiphumela engemihle ingenzeka, ukugadwa okufanele kwezokwelapha kanye nokuhambisana neziqondiso ezinqunyiwe kusiza ukuqinisekisa imiphumela engcono kakhulu engenzeka. Iziguli kufanele zikhumbule ukuthi ukuxhumana okuvulekile nodokotela wazo kuhlala kubalulekile kukho konke ukwelashwa kwazo.

Imibuzo Evame Ukubuzwa

1. Ingabe i-Metoclopramide iwumuthi onobungozi obukhulu?

I-Metoclopramide iphethe izingozi ezithile ezibalulekile, ikakhulukazi mayelana nokuphazamiseka kokuhamba. I-FDA ixwayise nge-tardive dyskinesia, engaba unomphela. Ubungozi buyanda ngobude besikhathi sokwelashwa kanye nemithamo eqoqwayo ephezulu.

2. I-Metoclopramide ithatha isikhathi esingakanani ukusebenza?

I-Metoclopramide iqala ukusebenza ngokushesha emzimbeni. Ngemuva kokuphathwa ngomlomo, kuthatha imizuzu engama-30 kuye kwengama-60 ukukhombisa imiphumela. Ngemithamo ye-intravenous, imiphumela ingabonakala phakathi kwemizuzu engu-1 kuya kwemi-3.

3. Kwenzekani uma ngiphuthelwa umthamo?

Iziguli kufanele zithathe umthamo ngokushesha nje lapho zikhumbula uma umthamo weqiwe. Kodwa-ke, uma cishe kuyisikhathi sedosi eshejuli elandelayo, yeqa ogejiwe. Ungalokothi uthathe umthamo ophindwe kabili ukuze ubuyisele ogejiwe.

4. Kwenzekani uma ngiphuza ngokweqile?

Izimpawu ze-overdose zidinga ukunakwa ngokushesha. Izimpawu ezijwayelekile ze-overdose zihlanganisa:

• Ukozela nokudideka
• Ukuyaluza nokungahlaliseki
• Ukuqina kwemisipha nokundindizela
• Ukushaya kwenhliziyo okungavamile
• Umkhuhlane kanye nomlomo owomile

5. Ubani ongakwazi ukuthatha i-prochlorperazine?

I-Prochlorperazine ayibafanele abantu abanezimo ezithile, kuhlanganise nalabo abane-glaucoma, amahlule egazi, izinkinga zesibindi, noma isithuthwane. Izingane ezingaphansi kweminyaka engu-2 ubudala noma ezinesisindo esingaphansi kuka-9 kg akufanele ziphuze lo muthi.

6. Zingaki izinsuku okufanele ngiphuze ngazo i-prochlorperazine?

Iziguli ngokuvamile zingathatha i-prochlorperazine kuze kube kathathu ngosuku lapho kudingeka. Kodwa-ke, ukusetshenziswa isikhathi eside kufanele kwenzeke kuphela ngaphansi kokuqondisa kwezokwelapha okuqondile.

7. Ungamisa nini i-prochlorperazine

Iziguli akufanele ziyeke ukuthatha i-prochlorperazine kungazelelwe ngaphandle kokubonisana nodokotela wazo, njengoba lokhu kungabangela izimpawu zokuhoxa. Isinqumo sokuyeka kufanele ngaso sonke isikhathi senziwe ngaphansi kokuqondisa kwezokwelapha.

8. Ingabe i-prochlorperazine iyizinso?

I-Prochlorperazine ngokuvamile iphephile ezinso, njengoba isibindi ngokuvamile sigaya lo muthi. Ezigulini ezinezinkinga zezinso, kuqashelwe ukuthi imiphumela emibi efana nokugcinwa koketshezi nokungalingani kwe-electrolyte ingase ibe nomthelela ongaqondile ekusebenzeni kwezinso.

9. Ngingakwazi yini ukuthatha i-prochlorperazine nsuku zonke?

Ukusetshenziswa kwansuku zonke kwe-prochlorperazine kungenzeka uma kunqunyiwe, kodwa ukusetshenziswa kwesikhathi eside kufanele kwenzeke kuphela ngaphansi kokuqondisa kodokotela. Ukuqapha njalo kusiza ukuqinisekisa ukuphepha nokusebenza ngempumelelo.