I-Quetiapine

I-Quetiapine

I-Quetiapine umuthi onamandla onomphumela omkhulu ezimpilweni zeziguli ezishikashikana nezimo zempilo yengqondo. Sivamise ukuhlangana nalesi sidakamizwa ngezindlela ezehlukene, okuhlanganisa amaphilisi e-quetiapine 25mg, ajwayele ukunikezwa ukusetshenziswa okuhlukahlukene. Ukusuka ekulawuleni izimpawu ze-schizophrenia kuya ekusizeni ukuphazamiseka kokulala, i-quetiapine isiphenduke ithuluzi elibalulekile enqolobaneni yokwelashwa kwezempilo yengqondo.

Kulesi sihloko, sizohlola ukungena nokuphuma kwe-quetiapine, ukusetshenziswa kwayo, ukuthi iyithatha kanjani, nokuthi yini okufanele uyiqaphele. Sizobheka imithamo ehlukene ye-quetiapine, okuhlanganisa ukusetshenziswa kwayo ukulala, izinkomba, imiphumela engemihle engaba khona, kanye nezinyathelo zokuphepha ezidingekayo okufanele uzikhumbule. 

Iyini i-Quetiapine?

I-Quetiapine umuthi onamandla we-antipsychotic esiwusebenzisela ukwelapha izimo ezahlukahlukene zempilo yengqondo. Iyingxenye yekilasi lemithi ebizwa ngokuthi i-atypical antipsychotics. Odokotela bavame ukunikeza amaphilisi e-quetiapine, okuhlanganisa i-quetiapine 25mg, yokulawula izimpawu ze-schizophrenia kubantu abadala kanye nezingane ezingaphezu kweminyaka engu-13 ubudala, i-bipolar disorder, nokushintshashintsha kwemizwelo ezigulini eziguquguqukayo. Ukusetshenziswa kwe-Quetiapine kudlulela ekwelapheni ukuphazamiseka okukhulu kokucindezeleka kubantu abadala uma kuhlanganiswe nama-antidepressants. I-Quetiapine isebenza ngokushintsha umsebenzi wezinto ezithile zemvelo ezisebuchosheni bethu, ikakhulukazi ezithintayo i-dopamine kanye namazinga e-serotonin. Lawa mahomoni alawula imizwa yethu, ukuziphatha, nemicabango.

Ukusetshenziswa kwe-Quetiapine

Odokotela basebenzisa isidakamizwa i-quetiapine ukwelapha izimo ezihlukahlukene zempilo yengqondo. Okulandelayo ezinye izinkomba ezijwayelekile ze-quetiapine: 

• Umuthi unomthelela ku-schizophrenia, usiza ukuphatha izimpawu kubantu abadala kanye nentsha engaphezu kweminyaka engu-13 ubudala. 
• Nge-bipolar I disorder, odokotela banquma i-quetiapine ukuze yelaphe kokubili iziqephu zokuhlanya nezokucindezeleka. Ingasetshenziswa yodwa noma ihlanganiswe ne-lithium noma i-valproate yokwelashwa kwesikhathi eside. 
• Ezinganeni ezineminyaka engu-10-17, odokotela basebenzisa i-quetiapine ukuze belaphe iziqephu ze-manic ezibangelwa ukuphazamiseka kwe-bipolar I. 
• Umuthi nawo uneqhaza ekwelapheni ukudangala okukhulu. 
• Odokotela bavame ukuyengeza ekwelashweni okukhona kwe-antidepressant lapho i-antidepressant eyodwa inganele ukuphatha izimpawu zokucindezeleka. 
• Ukuguquguquka kwe-Quetiapine kudlulela ekusetshenzisweni ngaphandle kwelebula, okuhlanganisa ukuphazamiseka kwengcindezi yangemva kwenhlekelele, ukuphazamiseka kokukhathazeka okujwayelekile, kanye nesifo sengqondo esihlobene Isifo sikaParkinson.

Ungayisebenzisa kanjani i-Quetiapine Tablet

• Abantu kufanele baphuze amaphilisi e-quetiapine njengoba nje udokotela wabo ebayalile ukuze bathole inzuzo enkulu. Kubalulekile ukuthi ungathathi okuningi, ukuthathe kaningi, noma ukusebenzise isikhathi eside kunesinqunyiwe. 
• Ungathatha amaphilisi e-quetiapine akhishwa ngokushesha ngokudla noma ngaphandle kokudla. 
• Kumaphilisi akhishwa isikhathi eside, wagwinye ephelele ngaphandle kokuwahlukanisa, ukuwahlafuna, noma ukuwachoboza. 
• Kubalulekile ukufunda umhlahlandlela wemithi ngokucophelela. Uma uphuthelwa umthamo, thatha ngokushesha ngangokunokwenzeka. Kodwa-ke, uma sekusondele isikhathi sethamo lakho elilandelayo, yeqa ogejiwe bese ubuyela esimisweni sakho esijwayelekile. 
• Gcina i-quetiapine esitsheni esivaliwe ekamelweni lokushisa, kude nokushisa, umswakama nokukhanya okuqondile.

Imiphumela emibi ye-Quetiapine Tablet

Imiphumela emibi evamile ihlanganisa: 

• Ukuzizwa ubuthongo emini 
• Izinkinga ngokunyakaza
• isiyezi
• Ukuphathwa yikhanda 
• Izinguquko ekudleni 
• Inzuzo yesisindo 
• ukuqunjelwa 
• Amabele avuvukele
• Izikhathi ezingajwayelekile
• Ukushaya kwenhliziyo okusheshayo
• Umbono ogqamile

Akuvamile, imiphumela emibi kakhulu ingase ivele, njenge:

• ukuquleka
• Ukuphelelwa amandla
• Ukushintsha kwengqondo/kwemizwa, njengokwanda kokukhathazeka, imicabango yokuzibulala
• Ukunyakaza okungalawuleki
• Uphawu lwezifo
• Izimpawu zamahlule egazi
• I-Neuroleptic malignant syndrome (engavamile)

Ukuqapha

• Ukuqapha Kwezokwelapha: Yazisa udokotela wakho mayelana nokungezwani komzimba wakho nomlando wemithi eqhubekayo, amavithamini, noma izithasiselo zemithi. 
• Izimo Zesistimu: Kufanele wazise odokotela ngezimo zakho zezokwelapha, ikakhulukazi izinkinga zesibindi, ukuquleka, noma izinkinga zenhliziyo. Kufanele futhi usho uma unesifo sikashukela noma umlando womndeni waso, njengoba i-quetiapine ingathinta amazinga kashukela egazini. 
• Utshwala: Kubalulekile ukugwema utshwala futhi uqaphe lapho ushayela noma usebenzisa imishini. 
• Ukukhulelwa Nokuncelisa: Uma ukhulelwe, uzama ukukhulelwa, noma ukuncelisa, xoxa ngezingozi nezinzuzo nodokotela wakho. 
• Abadala: Abantu abadala asebekhulile bathambekele kakhulu emiphumeleni emibi yalo muthi.

Ukuhlolwa njalo kanye nophenyo lwegazi kubalulekile ukuze kuqashwe noma yimiphi imiphumela emibi.

Isebenza kanjani i-Quetiapine Tablet

I-Quetiapine umuthi osiza ukulinganisa amakhemikhali athile ebuchosheni, angathuthukisa imizwa, ukucabanga, nokuziphatha. Ngokuvamile isetshenziselwa ukwelapha izimo ezinjenge-schizophrenia, i-bipolar disorder, futhi ngezinye izikhathi ukucindezeleka.

I-Quetiapine isebenza ngokuthinta ama-neurotransmitters (amakhemikhali emvelo ebuchosheni) abizwa ngokuthi i-dopamine ne-serotonin. Ngokulinganisa lezi, kungasiza ukunciphisa izimpawu ezifana nokubona izinto ezingekho, ukushintshashintsha kwemizwelo, nemicabango eyeqisayo.

Kucabange "njengesinzisi" sobuchopho bakho, busize ukuthi buhlale bulinganisele futhi buzolile, okungenza kube lula ukulawula imizwa futhi uzizwe ulawula kakhulu.

Ngingakwazi Ukuthatha I-Quetiapine Neminye Imithi?

I-Quetiapine ingasebenzisana nezidakamizwa eziningi, njenge:

• Utshwala
• Ama-antibiotic afana ne-moxifloxacin
• antidepressant
• Imithi ye-antifungal efana ne-itraconazole, ketoconazole
• Ama-Antihistamine afanayo cetirizine or i-diphenhydramine
• Amiodarone
• I-Carbamazepine
• Ijusi lamagilebhisi
• Ukudambisa izinhlungu ze-opioid njenge-codeine, i-hydrocodone
• Phenytoin 
• I-Sotalol
• Thioridazine

Ulwazi Lomthamo

Odokotela basebenzisa imithamo eyahlukene ye-quetiapine kuye ngesimo eselashwayo. 

Ku-schizophrenia kubantu abadala, odokotela bavame ukuqala ngo-25mg kabili ngosuku, kancane kancane bakhuphuke baye ku-300-400 mg nsuku zonke ngemithamo ehlukanisiwe. Umthamo wesondlo usukela ku-150 kuye ku-750mg ngosuku.

Lapho ukwelapha i-bipolar mania, odokotela baqala ngo-50mg kabili ngosuku, bakhuphuke baye ku-400-800 mg nsuku zonke. 

Ngokucindezeleka okuguquguqukayo, odokotela baqala ngo-50mg kanye ngosuku ngesikhathi sokulala, bakhuphuke baye ku-300 mg nsuku zonke. 

Ezinganeni ezineminyaka engu-10-17 ezine-bipolar mania, odokotela basebenzisa imithamo ephansi, eqala ku-25mg kabili ngosuku futhi ingeqi ku-600 mg ngosuku. 

Kubalulekile ukulandela imiyalelo kadokotela wakho ngokucophelela futhi ungashintshi umthamo ngaphandle kokubonisana nabo. 

Isiphetho

Umuthi we-Quetiapine unomthelela omkhulu ekwelapheni izimo ezihlukahlukene zempilo yengqondo, unikeza isixazululo esiguquguqukayo sokulawula izimpawu ze-schizophrenia, i-bipolar disorder, nokucindezeleka okukhulu. Indlela yayo yokusebenza eyingqayizivele, ethinta amasistimu we-neurotransmitter amaningi ebuchosheni, iyenza ibe yimpahla ebalulekile endaweni yokwelapha yezempilo yengqondo. Kodwa-ke, kuyadingeka ukukhumbula ukuthi i-quetiapine, njenganoma yimuphi umuthi onamandla, iza nemiphumela engemihle engaba khona futhi idinga ukucatshangelwa ngokucophelela lapho isetshenziswa kanye neminye imithi.

Imibuzo Evame Ukubuzwa

1. I-quetiapine isetshenziselwa ini ngokuyinhloko?

Odokotela basebenzisa i-quetiapine ukwelapha izimo ezihlukahlukene zempilo yengqondo. Inomthelela ku-schizophrenia, i-bipolar disorder, nokucindezeleka okukhulu. Ibuye isetshenziswe njengokwelashwa okungeziwe kubantu asebevele bethatha ama-antidepressant lapho i-antidepressant eyodwa inganele ukuphatha izimpawu zokucindezeleka.

2. Kungani i-quetiapine isengozini enkulu?

I-Quetiapine ibhekwa njengengcuphe ephezulu ngenxa yemiphumela emibi engaba khona kanye nokusebenzisana. Kungabangela ukuhlukahluka kwamazinga kashukela egazini, okwandisa ingozi yesifo sikashukela. Umuthi ungase futhi uholele ekuzuzeni isisindo kanye nezinguquko kumazinga e-cholesterol, okuyizici eziyingozi zesifo senhliziyo nemithambo yegazi. I-Quetiapine ingabangela ukozela nesiyezi, okwandisa ingozi yokuwa, ikakhulukazi kubantu abadala. Kukhona futhi ingozi ye-neuroleptic malignant syndrome, isimo esingavamile kodwa esinzima. Kwezinye izimo, i-quetiapine ingabangela imicabango yokuzibulala, ikakhulukazi kubantu abadala nasezinganeni.

3. Ubani okungafanele asebenzise i-quetiapine?

Odokotela bayeluleka ngokumelene nokusebenzisa i-quetiapine ezimeni ezithile. Akuvunyelwe ukwelapha izinkinga zokuziphatha ezihambisana nokuwohloka komqondo kubantu abadala asebekhulile ngenxa yengozi enkulu yokufa. Izingane ezingaphansi kweminyaka eyishumi akufanele zisebenzise i-quetiapine. Abantu abanomlando wezinkinga zenhliziyo, isifo sesibindi, noma isifo sikashukela kufanele bayisebenzise ngokuqapha. Abesifazane abakhulelwe nomama abancelisa ibele kufanele baxoxe ngezingozi nezinzuzo nodokotela wabo ngaphambi kokusebenzisa i-quetiapine. 

4. Ingabe i-quetiapine iphephile enhliziyweni?

Umthelela we-Quetiapine empilweni yenhliziyo uyakhathaza. Kungabangela izinguquko kusigqi senhliziyo, kuhlanganise nokwelulwa kwe-QT, okungase kuholele ku-arrhythmias enzima. Ukusetshenziswa kwe-Quetiapine kuhlotshaniswa nengozi eyengeziwe yokushaywa unhlangothi, isifo senhliziyo esishubile, kanye isifo se-artery coronary. 

5. Ingabe KULUNGILE ukuphuza i-quetiapine nsuku zonke?

Sivame ukunikeza i-quetiapine ukuze isetshenziswe nsuku zonke ekwelapheni izimo ezihlukahlukene zempilo yengqondo. Ngokuvamile kuphephile ukuphuza i-quetiapine nsuku zonke njengoba uqondiswa udokotela wakho.