I-Terbutaline

I-Terbutaline

Ubunzima bokuphefumula bungahlasela noma ubani noma nini, okwenza imisebenzi yansuku zonke elula izwakale njengezinselele ezinkulu. Ezigidini zabantu emhlabeni wonke, i-terbutaline iwumuthi obalulekile osiza ukuphatha lezi zinselele zokuphefumula ngempumelelo.

Lo mhlahlandlela obanzi uhlola konke iziguli okudingeka zazi mayelana nemithi ye-terbutaline, okuhlanganisa ukusetshenziswa kwayo, ukuphatha okufanele, imiphumela engemihle engase ibe khona, kanye nezinyathelo zokuphepha ezidingekayo okufanele zicatshangelwe ngesikhathi sokwelashwa.

Iyini i-Terbutaline?

I-Terbutaline umuthi onamandla okuyingxenye yezidakamizwa ezibizwa ngokuthi ama-beta-agonists. Ukusebenza kahle komuthi kuvela emandleni awo okusebenza ngqo emisipha ezungeze imigudu yomoya. Uma ilawulwa, i-terbutaline yenza kusebenze ama-receptors athile aqala ukukhululeka kwemisipha ebushelelezi kuma-bronchioles. Lesi senzo sisiza ukudala imigudu yomoya ebanzi, ukuthuthukisa ukugeleza komoya nokuphefumula kalula.

Ukusetshenziswa kwethebhulethi ye-Terbutaline

Ukusetshenziswa okuyinhloko kwe-terbutaline kufaka:

• Ukwelashwa isifuba kanye nokuphelelwa umoya ngenxa yezinkinga zamaphaphu
• Ukuphathwa kwezifo ezingapheli ze-pulmonary (COPD)
• Ukulawulwa kwe ufuba izimpawu ezigulini ezineminyaka eyishumi nambili nangaphezulu
• Ukukhululwa ebunzimeni bokuphefumula obubangelwa i-bronchitis kanye i-emphysema

Ungayisebenzisa kanjani i-Terbutaline Tablet

Umuthi udinga indlela ehlelekile yokwenza umthamo. Nazi iziqondiso ezibalulekile zokuthatha amaphilisi e-terbutaline:

• Thatha imithi ngezikhathi ezifanayo usuku ngalunye ukuze uthole imiphumela engcono kakhulu
• Landela ishejuli enqunyiwe kathathu ngosuku
• Imithamo yesikhala cishe ngamahora ayisithupha ngokwehlukana

Imiphumela Emibi Yethebhulethi ye-Terbutaline

Abantu abaningi bathola imiphumela engemihle lapho beqala ukwelashwa kwe-terbutaline. Imiphumela emibi evamile ihlanganisa:

• Ukuthuthumela noma ukuthuthumela, ikakhulukazi ezandleni
• Ikhanda elibuhlungu nesiyezi
• Ukuzwa uvalo noma ukukhathazeka
• Ama-cramp muscle
• Ukushaya kwenhliziyo okusheshayo kunokujwayelekile
• Ukuphazamiseka kokulala
• I-nausea noma ukuphatheka kabi kwesisu

Imiphumela emibi kakhulu ihlanganisa ubuhlungu besifuba, ukushaya kwenhliziyo okungajwayelekile, isiyezi esinzima, noma ukujuluka okungajwayelekile. Uma ukuphefumula kuba nzima kakhulu noma ukukhwehlela kukhuphuka ngemva kokuthatha i-terbutaline, iziguli kufanele zifune usizo lwezokwelapha oluphuthumayo.

Ukuqapha

Ukungezwani komzimba: Iziguli ezinomlando wokungezwani komzimba kuma-bronchodilator afanayo noma izidakamizwa ze-sympathomimetic kufanele zigweme ukuthatha i-terbutaline. 

Izimo Zezokwelapha: Iziguli kufanele zazise odokotela bazo uma zine:

• Isifo senhliziyo noma ukushaya kwenhliziyo okungajwayelekile
• Umfutho wegazi ophezulu
• Seizure ukuphazamiseka
• Diabetes
• I-thyroid engasebenzi ngokweqile
• Amazinga e-potassium aphansi

Ukukhulelwa: Uma ukhulelwe noma uzama ukukhulelwa, thintana nodokotela wakho uma lo muthi ufanelekile kuwe.

Isebenza kanjani i-Terbutaline Tablets

Lapho isiguli sithatha i-terbutaline, iqala ukusabela kweketanga kumaseli omzimba. Umuthi usebenza ngenqubo eyinkimbinkimbi:

• Yenza kusebenze ama-beta-2 ama-receptors athile kuma-bronchioles
• Icupha ukukhiqizwa kwento ebizwa ngokuthi i-adenylyl cyclase
• Yandisa amazinga e-cyclic adenosine monophosphate (cAMP)
• Yehlisa amazinga e-calcium ngaphakathi kwamaseli
• Yenza kusebenze amaprotheni athile asiza imisipha ukuba ikhululeke

Umphumela wokugcina wale nqubo ukuphumula kwemisipha ebushelelezi emigwaqweni yomoya. Lokhu kuphumula kubalulekile kuma-bronchioles - imigudu yokuphefumula emincane emaphashini. Lapho le misipha ikhululeka, imigudu yomoya iyavuleka, okwenza kube lula ukuthi umoya ugeleze.

Ngingathatha i-Terbutaline Neminye Imithi?

Izinhlobo eziningana zemithi zidinga ukunakwa okukhethekile lapho zithathwa nge-terbutaline. 

• Ama-antidepressants, ikakhulukazi ama-antidepressants ama-tricyclic afana i-amitriptyline kanye ne-doxepin, kungandisa ingozi yemiphumela emibi. 
• Ama-Beta-blockers angase anciphise ukusebenza kwe-terbutaline ekwelapheni izimpawu zesifuba somoya.
• Ama-MAOI, okuhlanganisa i-phenelzine ne-selegiline, adinga ukuqapha ngokucophelela lapho esetshenziswa eduze kwe-terbutaline.

 Ulwazi Lomthamo

Kubantu abadala kanye nentsha engaphezu kweminyaka eyi-15, ishejuli yomthamo enconyiwe ihlanganisa:

• Umthamo wokuqala - 5 mg izikhathi ezintathu ngosuku
• Umthamo wesondlo- 2.5 mg njalo emahoreni ayisithupha
• Umkhawulo omkhulu wansuku zonke ngu-15 mg

Entsha ephakathi kweminyaka engu-12 nengu-15 ubudala, odokotela banquma:

• 2.5 mg kathathu ngosuku
• Umthamo omkhulu wansuku zonke ongadluli ku-7.5 mg

Isiphetho

I-Terbutaline ime njengomuthi obalulekile kubantu abanenkinga yokuphefumula. Le bronchodilator enamandla isiza iziguli ukuthi zilawule ubunzima bazo bokuphefumula ngesenzo sayo esiqondiswe emisipha yomoya. Nakuba imithi idinga ukunakwa ngokucophelela kumashejuli omthamo kanye nokusebenzisana okungaba khona, izinzuzo zayo ziyenza ibe inketho yokwelapha ebalulekile ezigulini eziningi.

Iziguli ezilandela imihlahlandlela efanele yomthamo futhi zihlale ziqaphela imiphumela engemihle engase ibe khona ngokuvamile zibona ukuthuthuka okuphawulekayo ekuphefumuleni kwazo. Ikhono lomuthi lokusebenza kanye nezinye izindlela zokwelapha lengeza ekusebenzeni kwayo ekulawuleni izimo ezihlukahlukene zokuphefumula.

Impumelelo nge-terbutaline incike ekuxhumaneni okuvulekile nodokotela, amashejuli emithi angashintshi, kanye nokuqapha ngokucophelela noma yiziphi izinguquko zezimpawu. Iziguli kufanele zikhumbule ukuthi lo muthi usebenza njengengxenye yesu elibanzi lokwelapha, elisebenza kangcono kakhulu uma lihlanganiswa nokuhlolwa kwezokwelapha okuvamile kanye nezinqubo zokunakekelwa okufanele zokuphefumula.

Imibuzo Evame Ukubuzwa

1. Ingabe i-terbutaline iwumuthi onobungozi obukhulu?

I-Terbutaline ithwala ubungozi obukhulu uma isetshenziswa ngendlela engafanele. I-FDA yengeze isexwayiso sebhokisi elimnyama, ikakhulukazi mayelana nokusetshenziswa kwayo ngesikhathi sokukhulelwa. Iziguli ezinezimo zenhliziyo, isifo sikashukela, noma izinkinga zegilo zidinga ukuqapha ngokucophelela ngenkathi zithatha le mithi.

2. Ithatha isikhathi esingakanani i-terbutaline ukusebenza?

Umuthi ngokuvamile uqala ukusebenza emaminithini wokuphathwa. Ngemithamo yomlomo, i okwelaphayo umphumela ngokuvamile uhlala amahora ayisithupha.

3. Kwenzekani uma ngiphuthelwa umthamo?

Uma iziguli ziphuthelwa umthamo, kufanele ziwuthathe ngokushesha, njengoba zikhumbula. Kodwa-ke, uma kuseduze nethamo elihleliwe elilandelayo, kufanele beqe umthamo abagejiwe futhi baqhubeke neshejuli yabo evamile.

4. Kwenzekani uma ngiphuza ngokweqile?

Izimpawu ze-overdose zingabandakanya:

• Ubuhlungu besifuba obukhulu
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Isiyezi esidlulele
• ukuquleka
• Izinwele ezinzima

5. Ubani ongakwazi ukuthatha i-terbutaline?

Abantu abanezimo ezithile kufanele bagweme i-terbutaline:

• Labo abanokungezwani komzimba okwaziwayo emithini efanayo
• Iziguli ezinezimo zenhliziyo ezinzima
• Abantu abangalawulwa yegilo izinkinga

6. Ingabe i-terbutaline iyasikhulula isibeletho?

Yebo, i-terbutaline ingaphumuza imisipha yesibeletho. Kodwa-ke, ngenxa yezingozi ezingathi sína, i-FDA ixwayisa ngokusetshenziswa kwayo ukuvimbela umsebenzi ngaphambi kwesikhathi esingaphezu kwamahora angama-48-72.

7. Ingabe i-terbutaline iyakwandisa umfutho wegazi?

Umuthi ungathinta amazinga omfutho wegazi. Ezinye iziguli zingase zibe nezinguquko kumfutho wegazi, ikakhulukazi phakathi nokwelashwa kokuqala.

8. Ingabe i-terbutaline ne-salbutamol ziyefana?

Nakuba afana, awafani. U-Terbutaline wabelana ngephrofayela efanayo salbutamol, kanye namaphrofayili abo okusabela okungalungile ayaqhathaniswa ngemithamo elinganayo.