Inani eliphakeme kakhulu lama-TSH

Amazinga e-TSH akhuphuka ngaphezu kobubanzi obujwayelekile ngokuvamile abonisa ukuthi indlala yegilo ayikhiqizi amahomoni anele. Odokotela basibiza lesi simo i-hypothyroidism.

Ibanga elijwayelekile le-TSH liwela phakathi kwamamilimitha angu-0.4 no-4.0 ilitha ngalinye (mU/L). Ukufundwa ngaphezu kwalolu hlu kukhomba ku-hypothyroidism emnene, kuyilapho amazinga angaphezu kuka-10 mU/L ephakamisa isimo esibi kakhulu. Imizimba yabantu isabela ekukhuphukeni kwe-TSH ngezindlela ezihlukahlukene. Izimpawu ezijwayelekile zihlanganisa ukukhathala njalo, ukukhuluphala okungalindelekile, ukuzwela emakhazeni, isikhumba esomile, Futhi ukucindezeleka. Ngaphezu kwalokho, lezi zimpawu zivame ukuba zimbi ngaphandle kokwelashwa futhi zingase ziholele ezinkingeni zempilo ezingathi sína ezithinta inhliziyo nokuzala.

Odokotela basebenzisa ukuhlolwa kwe-TSH njengethuluzi labo eliyinhloko lokuhlola izinkinga ze-thyroid. Iminyaka yobudala, imithi, nokukhulelwa konke kungathinta imiphumela yokuhlolwa. Izinga le-TSH elivamile lowesifazane okhulelwe liyashintsha phakathi nokukhulelwa kwakhe. Ibanga le-trimester yokuqala liqala ku-0.1-2.5 mU/L futhi liyenyuka ngezigaba zakamuva. Ukufunda ngezimbangela ze-TSH ephezulu kwabesifazane nabesilisa kanye nokubona izimpawu eziyisixwayiso kusenesikhathi kusiza abantu bathole ukwelashwa ngaphambi kokuba kuvele izinkinga.

Iyini i-TSH ephezulu?

Odokotela bayibiza ngokuthi i-TSH ephakeme ngesikhathi ukufundwa kudlula amamilimitha angu-4.0-4.5 ilitha ngalinye (mU/L). I-thyroid yakho ayenzi amahomoni anele, okwenza i-pituitary yakho ikhulule i-TSH eyengeziwe ukuze inxephezele. Lesi simo sithinta izigidi emhlabeni jikelele, futhi siyazi njenge-hypothyroidism. Ochwepheshe bezokwelapha baphakamisa ukuthi ububanzi obujwayelekile kufanele bube buncane—phakathi kuka-0.4-2.5 mU/L. Amazinga angaphezu kuka-2.5 mU/L angase abonise izinguquko zangaphambi kwesikhathi ze-metabolic.

Izimpawu ze-TSH ephezulu

Umzimba wakho wehla kakhulu njengoba amazinga e-TSH ekhuphuka. Qaphela lezi zimpawu zamazinga aphezulu e-TSH:

• Ukukhathala njalo nokuntuleka kwamandla
• Ukuzwela amakhaza okungajwayelekile
• Ukushintsha kwemizwa, ikakhulukazi ukucindezeleka
• Inkungu yengqondo
• Ukukhuluphala ngaphandle kokushintsha imikhuba yokudla

Abantu bavame ukuba nesikhumba esomile, ukuncipha kwezinwele, izwi elihoshayo, ubuhlungu bemisipha, izinhlungu zamalunga, ukuqunjelwa, nezikhathi ezinzima njengoba isikhathi siqhubeka. Lezi zimpawu zikhuphuka kancane, zenze kube lula ukuzisusa njengokuguga okuvamile noma ukucindezeleka.

Izingozi

I-TSH ephezulu ibeka impilo yakho engcupheni, ikakhulukazi impilo yenhliziyo yakho. Umfutho wegazi ukhuphuka kaningi ezinganeni ezikhuluphele ezine-TSH ephezulu. Ucwaningo luqhubeka luthola ukuxhumana phakathi kwe-TSH ephezulu nezinombolo ze-cholesterol ephansi-i-cholesterol ephezulu "embi" ye-LDL, ama-triglycerides amaningi, kanye ne-cholesterol "enhle" ye-HDL ephansi.

Izinkinga ze-TSH ephezulu

I-TSH ephezulu idala izinkinga ezinkulu uma ingelashwa. Indlala yegilo yakho iba nkulu (i-goiter) njengoba izama ukumunca i-iodine eningi futhi yenze amahomoni. 

Izinkinga zenhliziyo ziba ezikhathazayo ikakhulukazi, namathuba aphezulu okushaya kwenhliziyo okungajwayelekile, ukuhluleka kwenhliziyo, kanye unhlangothi. 

Ezinye izindaba ezibucayi zihlanganisa: 

• Umonakalo wezinzwa
• Izinkinga zokuzala
• Izinkinga zokukhulelwa
• Izinkinga zentuthuko ezinganeni
• I-Myxoedema coma—isimo esiphuthumayo esisongela ukuphila

Sifo

Ukuhlolwa kwegazi kusebenza njengethuluzi eliyinhloko lokuxilonga i-TSH ephezulu njengoba izimpawu zizodwa azikwazi ukunikeza impendulo eqondile. Odokotela bakala amazinga e-thyroid-stimulating hormone (TSH) njengesinyathelo sokuqala. Ukufundwa okuphezulu kuholela ekuhlolweni okuphindaphindiwe, kanye nezilinganiso zamahomoni egilo i-T4 futhi, ngezinye izikhathi, i-T3. I-TSH ephezulu ehlanganiswe ne-T4 ephansi iqinisekisa i-hypothyroidism. Isimo sakho singase sibe i-subclinical hypothyroidism uma i-TSH yakho iphezulu, kodwa i-T4 ne-T3 zihlala zijwayelekile - ifomu elithambile elingavamile ukukhombisa izimpawu eziphawulekayo.

Ukwelashwa kwe-TSH ephezulu

Levothyroxine (Synthroid, Levo-T) isebenza njengesisekelo sokwelashwa kwe-hypothyroidism. Le mithi yomlomo yansuku zonke ibuyisela amazinga e-hormone futhi idambise izimpawu. Iningi leziguli lizizwa lingcono emasontweni angu-1-2 ngemva kokuqala ukwelashwa. Odokotela bavamise ukuqala iziguli esezikhulile noma labo abanezimo zenhliziyo ngemithamo ephansi. Ukuhlolwa kwe-TSH njalo emavikini angu-6-8 kusiza ukuthola umthamo ofanele. Ukuhlola konyaka kwanele uma amazinga ezinzile.

Uzoyibona Nini Udokotela

Udokotela wakho udinga ukwazi uma uhlangabezana nokukhathala okungachazwanga, izinguquko zesisindo, ukucindezeleka, ukuzwela amakhaza, noma ukungahambi kahle kokuya esikhathini. Ukuhlola okuvamile kuzuzisa abantu abanezigaxa zegilo, umlando womndeni wezifo zegilo, noma izimo ze-autoimmune. Indlala yegilo yabesifazane abakhulelwe idinga ukuqashwa ngokucophelela njengoba izidingo zishintsha phakathi nokukhulelwa. I-hypothyroidism engelashiwe ingaba yingozi futhi isongela ukuphila.

Ukuvimbela High TSH

Izifo eziningi zegilo zibangelwa izakhi zofuzo noma izimbangela ze-autoimmune futhi azikwazi ukuvinjelwa. Ukutholwa kusenesikhathi kuvela ekuhlolweni okuvamile. Abantu abasengozini kufanele bathole ukuhlolwa kwe-thyroid njalo ezinyangeni ezingu-6-12. Ukudla okunamazinga e-iodine enempilo kusekela ukusebenza kwe-thyroid, nakuba okuningi kungalimaza izimo ezithile. Ukuhlolwa kubaluleke kakhulu uma ungaphezu kweminyaka engama-60, ukhulelwe, noma unezifo ezizimele zokuzivikela komzimba thayipha 1 sikashukela.

Isiphetho

Amazinga aphezulu e-TSH adlala indima ebalulekile empilweni yakho yonke. Le hormone encane isebenza njengesithunywa phakathi kobuchopho bakho kanye nendlala yegilo. Umzimba wakho uthumela amasignali acacile adinga ukunakwa uma amazinga eba ngaphezu kobubanzi obujwayelekile.

Ungase ubone izimpawu eziyisixwayiso kusenesikhathi njengokukhathala okungajwayelekile, ukuzwela emakhazeni, noma ukuzuza kwesisindo okungalindelekile. Lezi zimpawu zingasiza ekubambeni izinkinga ze-thyroid kusenesikhathi. Ungalahli lezi zimpawu njengokuthi "ukuguga" noma "ukuzizwa ucindezelekile."

Abantu abaningi bathola ukwelashwa kulula. I-Levothyroxine isebenza ngokushintsha amahomoni egilo angekho, futhi iziguli ngokuvamile zizizwa zingcono phakathi namasonto. Umthamo ofanele uthatha isikhathi kanye nokuhlolwa okuvamile ukuze kunqunywe.

Ukushiya i-TSH ephezulu ingelashwa kungaholela ezinkingeni ezinkulu zempilo. Abantu abangazinaki izinkinga ze-thyroid ngokuvamile baba nezinkinga zenhliziyo nezinselele zokuzala. Noma ubani onezimpawu ezisolisayo kufanele abonane nodokotela wakhe ngokushesha.

Qaphela ukuthi i-thyroid yakho ithinta cishe zonke izinhlelo zomzimba wakho. Le ndlala encane emise okwemvemvane idinga ukunakekelwa okufanele ukuze ikhulise amandla akho, isimo sengqondo, nempilo yesikhathi eside. Naka izimpawu zomzimba wakho, thola ukuhlolwa okufanele, futhi unamathele ekwelashweni okunconyiwe. Le ndlela izonikeza i-metabolism yakho ukwesekwa okudingayo iminyaka ezayo.

Imibuzo Evame Ukubuzwa

1. Liyini izinga eliphezulu le-TSH eliyingozi?

Odokotela bacabanga ukuthi i-TSH engaphezu kuka-4.2 mU/L iphezulu futhi idinga ukwelashwa. Noma kunjalo, ukufundwa okuphakathi kuka-5.5-10 mU/L namazinga e-T4 avamile kungase kudingeke kuphela ukuqapha noma ukungenelela okuncane. I-TSH engaphezulu kuka-10 mU/L idinga nje ukwelashwa ngokushesha, ngisho nangaphandle kwezimpawu, njengoba leli zinga liphakamisa ubungozi bakho bokuthuthukisa i-hypothyroidism egcwele ngobuningi. Inhliziyo yakho, ukujikeleza, kanye cholesterol amazinga angahlupheka uma i-TSH ephezulu ingalashwa.

2. Yini okufanele udle futhi ungadli ku-hypothyroidism?

Ukudla kwakho kuyingxenye ebalulekile yokulawula ukusebenza kwegilo. Lokhu kudla okucebile nge-selenium kusekela umsebenzi we-thyroid onempilo:

• Ukukhetha okuhle - amantongomane aseBrazil, tuna, amaqanda, i-turkey, inkukhu, i-cottage shizi
• Qaphela - Imikhiqizo yesoya (ikakhulukazi eduze nesikhathi somuthi), imifino eluhlaza ye-cruciferous, gluten (uma izwela)
• Gwema - Umdumbula, izithako ze-iodine, ukudla okunamafutha, izinto ezigayiwe ezinesodium ephezulu, ushukela oweqile.

Thatha imithi yegilo imizuzu engu-30-60 ngaphambi kokudla kwasekuseni noma amahora angu-3-4 ngemva kwesidlo sakusihlwa ukuze umunce kahle kakhulu.

3. Ingabe i-TSH ephezulu iyelapheka?

Odokotela abaningi bathi i-hypothyroidism ingashintshwa ezimweni eziningi. Ngenkathi umuthi ojwayelekile uvame ukugxila emithini yempilo yonke, izindlela zokwelashwa ezisebenzayo zingasixazulula ngokuphelele lesi simo. Ukuthola kwakho kuncike ekukhulumeni ukuthi kungani kwenzeka. Uhlelo lomuntu siqu oluhlanganisa izinguquko zokudla, izithasiselo, ukulawula ingcindezi, nemithi efanele ikunikeza ithuba elingcono kakhulu lokululama.

4. Ingabe i-TSH ephezulu ingadala isifo sohlangothi?

Eqinisweni, izixhumanisi zocwaningo ziphakamise i-TSH engozini yokushaywa unhlangothi. Izinkinga ze-thyroid ezingalashwa zingakhuphula i-cerebrovascular atherosclerosis futhi ziholele ekushayweni kwe-ischemic. Iziguli ezisencane zibhekana nezingozi eziphezulu kunalezo ezineminyaka engaphezu kwengama-65 ubudala.

UDkt. Rahul Chirag

I-MBBS, MD (Imithi Yangaphakathi)
CARE Hospitals, HITEC City, Hyderabad

Ukuze Ubhukhe Isikhathi, shayela:

+ 91 40-68106529

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