Dr. Nikhilesh Jain

Director-Intensive Care Unit, Physician-Intensivist


Department of Internal Medicine




20 Years


CARE CHL Hospitals, Indore

Internal Medicine Doctor In Indore


After graduating from Gandhi Medical College, Bhopal, Dr. Nikhilesh Jain did his DNB (Medicine) from Apollo Hospitals, Chennai and went on to finish his MRCP (Ireland). He developed an interest in Critical Care and continued his work with Critical Care Services Apollo Hospitals Chennai where he worked in different capacities in the Department of Intensive Care including junior consultant and did his IDCCM training there. He joined Choithram Hospital as Chief intensivist and after a brief stint of about 3 years went on to join Bombay Hospital Indore as a consultant in Intensive Care.

In 2012, he went on to Join CHL Hospitals, Indore (Now CARE CHL Hospitals) as Director and Operational Head Dept of Critical Care Services and has been spearheading the 35 bedded unit since that point in time. He has more than 65 papers and several book chapters along with lectures at different forums to his credit and is also the scientific Co-Chair for Criticare 2023 (The annual meeting of the Indian Society of Critical Care Medicine). He has been awarded Dr. JC Patel and Dr. BC Mehta awards and the best poster award by the Indian Society of Critical Care Medicine. He has done his fellowship in ECMO and is an advanced WINFOCUS provider.

His areas of expertise include Neuro Critical Care, Sepsis, Acute care nephrology and CRRT/ECMO. He has been an abstract reviewer for Neurocritical care society on multiple occasions and has been a journal reviewer for many national and international journals.

Fields of Experience

  • Intensive Care
  • Internal Medicine
  • Haemodynamic Monitoring
  • Neuro Critical Care
  • Infectious Disease
  • Critical Care Sonography
  • ECMO and CRRT

Research Presentations

  • Phase IV trial in the efficacy of cefaclor in Upper respiratory tract infections
  • Phase III trial for the efficacy of Tigecycline in Pneumonias
  • Phase III trial for the efficacy of Conivaptan in Hyponatremia
  • Phase IV efficacy trial for insulin aspart in critically ill patients
  • Phase IV trial for the efficacy of Meropenem in serious infections
  • Phase IV trial for enoxaparin in DVT prophylaxis (LIFENOX)
  • Eurotherm trial (ESICM)
  • ELAXIM Indian registry for use of tenecteplase in ACS
  • PEACE Trial (ESICM)
  • INTUBE Trial (ESICM)
  • IO SWEANS Weaning Trial (CCTG)
  • SIPS


  • Angiographic correlates of Quantitative troponin-t in Unstable Angina-Ind Heart J 2000; 52:763; Stiff Person Syndrome. J Assoc Phys Ind Vol. 49, 568 - 570 May 2001
  • Lofgrens Syndrome - Our experience. J Assoc Phys Ind January 2002; 50:135; Is Thymectomy Redundant in Myasthenia Gravis? Annals of Indian Academy of Neurology, 2003 Vol.6, 63
  • Thymectomy in non - thymomatous Myasthenia Gravis - Can it be done away with? J Assoc Phys Ind Dec 2003; 51:2180
  • An unusual case of pulmonary edema - probably an index case. Apollo Hospital Proceedings, January 2004; Intra-aortic balloon counterpulsation
  • A bridge to recovery or a path downhill? Ind J Crit Care Med September 2003; 7:3:175
  • Myocarditis in an adolescent - A rare presentation of Kawasaki Disease. Ind J Crit Care Med September 2003; 7: 3: 205
  • Methemoglobinemia - An unusual presentation. Ind J Crit Care Med September 2003; 7: 3: 204
  • Prognostic factors in patients with acute pancreatitis admitted to the ICU. Ind J Crit Care Med September 2003; 7: 3: 205
  • Troponin - T: A noninvasive marker of multivessel involvement and complex lesion morphology in unstable angina. Ind J Crit Care Med September 2003; 7: 3: 204
  • Quality of Care for Patients undergoing bedside open Tracheostomy in Intensive Care Setting. Proceedings of ISACON December 2004, Abstract pg: 131
  • Thrombocytopenia as a marker of prognosis in critically ill. Ind J Crit Care Med Dec. 2004; 8: 4: 217
  • Pulmonary thromboembolism in a case of dysfibrinogenemia - A rare presentation of a rare problem. Ind J Crit Care Med Dec 2004; 8: 4: 233
  • Psychological disturbances in a coronary care unit. Ind J Crit Care Med Dec 2004; 8: 4: 235
  • Bedside open tracheostomy in the Intensive Care Setting - A Quality Initiative. Ind J Crit Care Med Dec 2004; 8: 4: 231
  • Troponins - Current status in coronary artery disease. J Assoc Phys IndFeb 2005; 53: 116-118
  • Bedside open tracheostomy in the Intensive Care Setting - A Quality Initiative. Proceedings of American Thoracic Society, Vol 2; 428: 2005
  • Self-extubation in critical care unit-A Quality Care Initiative. July 2005, 195. Scientific proceedings of Tamilnadu state Conference of Indian society of anaesthesiologists
  • Recombinant factor VIIa in nontraumatic haemorrhage. 77, Toronto Critical Care Medicine Symposium Oct 2005
  • Intramuscular administration of an OPC compound: A rare route for a common poison. Abstract 23 Criticare Jan. 2006. (ISCCM)
  • From penicillin resistance to meropenem resistance: Where are we heading? Abstract 24 Criticare, Jan.2006. (ISCCM)
  • Recombinant factor VIIa (rfVIIa) in non-trauma settings: Holy Grail for bleeding in critical care unit. Abstract 25 Criticare Jan.2006. (ISCCM)
  • OPC poisoning: an unusual cause of pulmonary edema. Abstract 1122 International conference of emergency medicine. June 2006; Intra-aortic balloon counterpulsation in cardiogenic shock: An intensivists perspective (Ind Heart J 2006; 58:494); Critical care in India. ICU management 2006/07; 6(4): 38
  • Outcomes in Sepsis: Does age really matter? Abstract 250, Conference proceedings Criticare Jan 2007(ISCCM); Outcome predictors in Acute renal failure cohorts on renal replacement therapy Abstract 238, Conference proceedings Criticare Jan 2007 (ISCCM)
  • Severity of illness scoring systems in obstetrics. Do the numbers match? 262, Conference proceedings Criticare 2008 (ISCCM)
  • Predicting outcomes in Traumatic brain injury (TBI). 250, Conference proceedings Criticare 2008 (ISCCM); Thrombocytopenia in sepsis: Outcome predictors. 240, Conference proceedings Criticare 2008 (ISCCM)
  • Does age have a role in the outcomes of sepsis? 290, Conference proceedings Criticare 2008 (ISCCM); Outcomes in hepatic failure. 243, Conference proceedings Criticare 2008 (ISCCM)
  • Tissue markers of perfusion: Search for the Holy Grail? Abstract, Conference proceedings Criticare 2009 (ISCCM)
  • Elevated HbA1C levels in sepsis: Do they affect prognosis? Abstract, Conference proceedings Criticare 2009 (ISCCM)
  • Abdominal compartment syndrome revisited Feb 2009; 10:1:38-40 Anesthesia newsletter Indian society of anesthesia Indore Chapter
  • Sepsis in elderly: Different? Proceedings of European Congress of Clinical Microbiology and Infectious Diseases 2009.Clinical Microbiology and Infection Volume 15, Suppl 4
  • Recruitment manoeuvres in ARDS Jun 2009; 10: 2: 26-28 Anesthesia newsletter Indian society of anaesthesia Indore Chapter;
  • Search for a better tissue perfusion marker. Abstract, Conference proceedings Criticare 2010 (ISCCM); Monograph on Colistin for MDR Organisms for Glenmark pharmaceuticals for Superbugsdotcom
  • Effectiveness of planned teaching program regarding peripheral intravenous infusion among staff nurses. Indian Journal of Nursing Studies Vol 2, No 1, 41-45, Jan-Jun 2011
  • Fat embolism: an overview. Anesthesia Newsletter [Indore Chapter ISA] Nov 2011; 12: 3: 40-41
  • Search for Holy grail: Tissue markers of sepsis (Intensive Care Medicine Supplement 1, Vol 38 S189 Annual Congress European Society of Intensive care Medicine October 2012)
  • ET tube in Emergency: Does size matter? (Intensive Care Medicine Supplement 2, Vol 39 S254 Annual Congress European Society of Intensive care Medicine October 2013)
  • Eye care in ICU: More than what meets the eye (Intensive Care Medicine Supplement 2, Vol 39 S454 Annual Congress European Society of Intensive care Medicine October 2013)
  • Sepsis in Diabetes: Are RBS and Hba1c similar (Intensive Care Medicine Supplement 2, Vol 39 S241 Annual Congress European Society of Intensive care Medicine October 2013)
  • Nosocomial meningitis: Does CSF lactate really help (Intensive Care Medicine Supplement 2, Vol 39 S231 Annual Congress European Society of Intensive care Medicine October 2013)
  • How to approach the unconscious patient in an emergency? An algorithmic approach to patients with stroke and haemorrhage (Souvenir article for first Zonal meet of Critical Care Bhopal 2013)
  • Subconjunctival edema in a case of ecclampsia: Probably an index case (Under Consideration)
  • Imidacloprid poisoning with methhemoglobinemia. (American Journal of Respiratory and Critical Care Medicine 2016;193:A1942)
  • Anesthesia and Intensive care considerations for HIPEC surgery. Indian Journal of Surgical Oncology 2016 (7); 208-14
  • Correlates of perfusion markers with baseline mortality prediction in ICU? An elusive search for the best performer Intensive care Medicine Experimental 2016,4(Suppl 1): A857
  • Tissue perfusion marker responses to fluid resuscitation? Search for an ideal marker Critical Care 2017,21 (Suppl 1): P120; Minocycline for ESBL Klebsiella Pneumoniae in an Infant: Ethical Dilemmas (American Journal of Respiratory and Critical Care Medicine 2017;195: A6104)
  • Imidacloprid Poisoning: An Indian experience Intensive care Medicine Experimental 2018 6 (Suppl 2):0802; Real-time assessment of tissue perfusion markers with fluid bolus in sepsis: time to change our targets?? Intensive care Medicine Experimental 2018 6 (Suppl 2):1218
  • Myroides UTI: An Indian Perspective (American Journal of Respiratory and Critical Care Medicine 2019;199: A6613)
  • Is high sugar really bad for septic patients?? A reality check. Intensive care Medicine Experimental 2019 7 (Suppl 3):1247
  • An interesting case summary of Tubercular pneumonia masquerading as viral pneumonia kept on extracorporeal membrane oxygenation. (Indian Journal of Tuberculosis Vol 67 Issue 2 Apr 2020; 268-73)
  • Metoclopramide induced Methemoglobinemia: Uncommon complication of a common drug (American Journal of Respiratory and Critical Care Medicine 2020; 201: A1705)
  • Thyroid Levels in ICU. More than sick euthyroid?? (Intensive Care Medicine Experimental 2020 8(2):000467); A case series on macrophage activation syndrome with infections. More common than we think?? (Intensive Care Medicine Experimental 2020 8(2):000560
  • Sphingomonas Paucimibilis infections: An Indian case series. Intensive care Medicine Experimental 2021, 9(1):000683; Pearl points in Meningitis. Critical Care Communications 37 Vol 16.5, Nov-Dec 2021
  • Telmisartan Amlodipine combination antihypertensive overdose. A first of its kind??Abstract 893 Jan 2022, Vol 50, No 1 (supplement) Crit Care Med
  • Cytomegalovirus (CMV) Reactivation in COVID-19: A Case Series American Journal of Respiratory and Critical care Medicine (AJRCCM) 2022;205:A1678
  • Cytomegalovirus Reactivation in COVID patients Chapter 149 Critical Care Update 2022. Continuous Renal Replacement Therapy: Dose and Prescription Chapter 51 Critical Care Medicine Bench to Bedside 1/edition
  • Estimates of Sepsis Prevalence and Outcomes in Adult Patients in the ICU in India: A Cross-sectional Study for SIPS (Sepsis in India prevalence study) Chest 2022 Jun; 161(6):1543-54


  • Postgraduate Program in Healthcare Management (Loyola Institute of Business Administration Chennai)
  • Adult International healthcare provider for ECMO certification
  • Fellow of College of Critical Care Medicine (Critical Care Education Foundation); Advanced level 1 provider certification for ultrasound in critical care by WINFOCUS
  • IDCCM (Critical Care) Apollo Hospitals, Chennai
  • MRCP (Ireland) RCPI
  • Postgraduate Diploma in Geriatric Care
  • Postgraduate Diploma in Diabetology (Annamalai University)
  • DNB (Medicine) - Apollo Hospitals, Chennai

Awards and Recognitions

  • BA in Classical Music (Prayag University)- Violin
  • Over 65 National and International Papers
  • Over 60 lectures as Faculty \ Chairperson \ Speaker on various National and International Forums
  • Scientific Co-chair for Criticare 2023 (National congress of ISCCM)
  • ACLS Instructor and advanced trainee for Winfocus
  • CCEF teacher and examiner for fellowship exam
  • Chairman and Secretary for ISCCM (Indore Branch) and Governor for M.P. chapter of CCEF
  • Abstract Reviewer for Neurocritical Care Society Meeting on three occasions

Languages Known

Hindi & English

Fellow Membership

  • Indian Diploma in Critical Care Medicine (ISCCM)
  • Fellowship in Critical Care Medicine (IBMS)
  • SCCM
  • ATS
  • ACCP
  • API
  • IMA
  • Neurocritical Care Society

Past Positions

  • 2012-till date: Chief Intensivist and Director Department of Critical Care Services, CARE CHL Hospitals, Indore
  • 2009-2012: Consultant Intensivist, Department of Critical Care Services. Bombay Hospitals, Indore
  • 2007-2009: Chief Intensivist. Department of Critical Care Services, Choithram Hospital, Indore
  • 2007: Junior Consultant Apollo Hospitals, Chennai
  • 2006: IDCCM Trainee Apollo Hospitals, Chennai
  • 2002-2005: Registrar Department of Critical Care, Apollo Hospitals, Chennai

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