Rheumatology Doctor in HITEC City, Hyderabad

Brief Profile

Dr. Sripurna Deepti Challa is a highly qualified Consultant Rheumatologist practicing at CARE Hospitals in HITEC City, Hyderabad. She holds an MBBS and MD, along with advanced specialization through a Fellowship in Rheumatology and a Master of Medicine (MMed) in Rheumatology. With extensive training and experience, Dr. Challa is dedicated to diagnosing and managing a wide range of rheumatic and autoimmune disorders, offering patient-centered care with a strong foundation in evidence-based medicine. Her clinical expertise and compassionate approach make her a trusted name in rheumatology.

Research and Presentations

• Study of Measurement of Knee Crepitations and their Analysis in Osteoarthritis (June- December 2006) (Studentship under Indian Council of Medical Research)
• Research Observer, Dept. Clinical Pharmacology & Therapeutics, Nizam’s Institute of Medical Sciences, Hyderabad (June- October 2010) - To study the Impact of aberrations in one-carbon metabolism on the breast cancer Phenotype and to investigate the role of plasma folate and polymorphisms in one-carbon metabolism on Catecholamine methyltransferase (COMT) H108L associated oxidative DNA damage and breast cancer risk
• Cardiovascular risk assessment in patients with Rheumatoid arthritis in a rural setup (2014-15)
• Assessment of Chronic Widespread Pain Program at Wrightinton Wigan and Leigh NHS Hospital Trust – A Clinical Service Evaluation, 2021
• Patient care management during COVID pandemic in patients with Rheumatological illness 

Publications

• Naushad SM, Pavani, Rupasree Y, Sripurna Deepti, Raju SGN, Raghunadha Rao, D, Vijay K. Kutala. Modulatory effect of plasma effect and polymorphisms in one-carbon metabolism on catecholamine methyltransferase (COMT) H108L associated oxidative DNA damage and breast cancer risk. Indian J Biochem Biophys: 2011; 43: 283-289.
• Naushad SM, Pavani A,  Roopa Y, Raju, Shree Divyya, Sripurna Deepti, GSN, Raghunadha Rao, D, Vijay K. Kutala. Aberrations in one-carbon metabolism influence molecular phenotype and grade of breast cancer. Molecular Carcinogenesis, DOI 10.1002/mc.21830 2011, 1-10.
• U R K Rao, Maryam Younis, Sripurna Deepti.   Rheumatoid Arthritis: Principles of Management.  In the Monograph Rheumatoid Arthritis 2012.
• S. Arava, R. R. Uppuluri, F. Fatima, M. Y. Mohiuddin, A. Rani, D.Kumar, S. Challa, S. Jonnada , D. Sripurna Deepti. Side Effect Profile in Patients with Rheumatoid Arthritis on Leflunomide with and without loading dose. Annals of Rheumatic Diseases 2013; 72 (S3); 1099.
• V Krishnamurthy, Sripurna Deepti; Psoriatic Arthritis - Clinical Features and Management: Manual of Rheumatology, 4th Ed: Editor in Chief; U R K Rao 2014; 214-220.
•  U R K Rao, Sripurna Deepti. Gout and other Crystal Arthritides. API Textbook of Medicine, 10th  Ed: Editor in Chief  Y P Munjal, Jaypee Brothers, New Delhi  2015: 2483-91.
• U Ramakrishna Rao, A Shashikala, B Naina, Y Maryam, F Firdaus, R Archana, K Datta, J Shivanand, D Sripurna, C Shivashankar, C Satyavati. Impact of latent tuberculosis in the recruitment of subjects for clinical drug trials in rheumatoid arthritis. IJR 2015; 18 (Suppl. 1): 22.
• B Naina, A Shashikala, Y Maryam, F Firdaus, R Archana, K Datta, J Shivanand, D Sripurna, C Shivashankar, C Satyavati, U Ramakrishna Rao. Commonly encountered reasons for screen failure in clinical drug trials. IJR 2015; 18 (Sup1): 67.
• U Ramakrishna Rao, D Sripurna, A Shashikala, B Naina, Y Maryam, F Firdaus, R Archana, J Shivanand, K Datta, C Shivashankar, C Satyavati. Causes of discontinuation of subjects during clinical drug trials. IJR 2015; 18 (Suppl. 1): 67.
• K Madasu, VMK Raja, K Datta, R Archana, A Shashikala, F Firdaus, J Shivanand, D Sripurna, RR Uppuluri. Association of periodontitis with rheumatoid arthritis. IJR 2015; 18 (Suppl. 1): 97.
• N. Bhanushali, R.R. Uppuluri, S. Arava, M. Younis, F. Fatima, A. Rani,     D. Kumar, S. Jonnada, S. Deepti, S. Challa, S. Challa. Challenges in recruitment and retention of subjects in conducting clinical drug trials in a developing country. Annals of Rheumatic Diseases 2016; 75(S2): 1255.
•  Ramakrishna Rao Uppuluri, Sripurna Deepti Challa. Oral Targeted Treatments in RA –Update 2021. In Medicine Update Vol 31, Editor-in-Chief Kamlesh Tewary,  Evangel New Delhi  2021: 1338-46.
• Ramakrishna Rao Uppuluri, Sripurna Deepti Challa. Septic Arthritis. In Urgencies and Emergencies in Rheumatology 2nd Ed, Eds Aman Sharma, Rohini Handa, Evangel New Delhi 2021: 187-97.
• Ramakrishna Rao Uppuluri, Sripurna Deepti Challa. Sjogren’s Syndrome. In Postgraduate Text Book of Medicine Vol 3, Editor-in-Chief Gurpreet Wander, Jaypee Brothers New Delhi 2022: 1887-94.
• Ramakrishna Rao Uppuluri, Sripurna Deepti Challa. Classification Criteria. In Rheumatology Clinics Rheumatoid Arthritis Eds. Aman Sharma, Rohini Handa, Evangel New Delhi 2022: 37-41.
• Cross -sectional study of a cohort of rheumatoid arthritis patients from a tertiary rheumatology centre in Hyderabad, G L Lavanya, U R K Rao, Md Ishaq, C Satyavati, Sripurna Deepti, S Archana, Y Maryam, A Shashikala presented at IRACON 2012, Ahmedabad.
• Cytokines in rheumatoid arthritis. Surekha Rani H, Rajesh Kumar G, Firdaus Fatima, Shivanand J, Datta Kumar, U R K Rao, Sripurna Deepti.  Presented at IRACON-2013, Kolkata.
• An examination of Interleukin-1RN VNTR Polymorphisms in Indian Rheumatoid Arthritis patients.  G Lavanya, U R K Rao, Datta Kumar, Firdaus Fatima, Sripurna Deepti, M Ishaq.  Presented at IRACON-2013,  Kolkata.
• Impact of latent tuberculosis in the recruitment of subjects for clinical drug trials in Rheumatoid arthritis. Shashikala Arava, Naina Bhanushali, Maryam Younis, Firdaus Fatima, Archana Rani, Datta Kumar, Shivanand Jonnada, Sripurna Deepti, Shivashankar Challa, Satyavati Challa, Ramakrishna Rao Uppuluri. Presented at APLAR 2015, Chennai.
• Causes of subject discontinuation during clinical drug trials. Shashikala Arava, Naina Bhanushali, Maryam Younis, Firdaus Fatima, Archana Rani, Datta Kumar, Shivanand Jonnada, Sripurna Deepti, Shivashankar Challa, Satyavati Challa, Ramakrishna Rao Uppuluri. Presented at APLAR 2015, Chennai.
• Commonly encountered reasons for screen failure in clinical drug trials. Naina Bhanushali, Shashikala Arava, Maryam Younis, Firdaus Fatima, Archana Rani, Datta Kumar, Shivanand Jonnada, Sripurna Deepti, Shivashankar Challa, Satyavati Challa, Ramakrishna Rao Uppuluri. Presented at APLAR 2015, Chennai.
• TOXIC EPIDERMO NECROLYSIS. Deepti Sripurna, Prasanna PV, Datta AS, Veravalli Sarath Chandra Mouli. Presented at SZIRACON 2017, Hyderabad.
• A Short experience of Tofacitinib in Rheumatoid Arthritis from a single centre. U R K Rao, C Satyavati, Sripurna Deepti, J Shivanand, Datta Kumar, S Archana Rani, Maryam Younis, A Shashikala. Presented at SZIRACON 2017, Hyderabad.
• Assessment of DEXA scanning in patients under 40 years of age. Deepti Challa, Laura Chadwick, Kiran Putchakayala. Presented at EULAR 2019, Madrid.
• Extra-articular manifestations of Rheumatoid arthritis – a comprehensive outlook in a single patient. Presented at MRA Feb 2021, Manchester.
• Polymimicks – an unusual presentation of progressive muscle weakness. Presented at a virtual Indo-UK conference in May 2021.
• Management of Ankylosing Spondylitis in a patient with a history of malignancy and a background failure of IL-17 inhibitors – A clinical challenge MRA Nov 2021, Manchester.
• A case series of progressive muscle weakness – A clinical conundrum in diagnosing Inflammatory muscle disorder. Presented May 2022. CRC KIMS Hyderabad.
• Myths and Facts in Rheumatology – Faculty member talk at Rheumatology workshop, KIMS Hyderabad. Presented July 2022.
• Ocular Manifestations of Bechet’s Syndrome – Speaker in SZIRACON, September 2022 Visakhapatnam.

Education

• MBBS - Deccan College of Medical Sciences, Hyderabad, (2010) (Affiliated with N.T.R. University of Health Sciences)
• MD (Medicine):  Meenakshi Institute of Medical Sciences Kanchipuram (2012-2015)
• Fellowship in Rheumatology – Krishna Institute of Medical Sciences, Hyderabad (2018)
• MMed Rheumatology – Edge Hill University and Wrightington Hospital, (2022)

Past Positions

• Junior Consultant Rheumatologist at Sri Deepti Rheumatology Centre, Hyderabad (April 2022 to Date)
• Clinical and Research Assistant at Sri Deepti Rheumatology Centre, Hyderabad (Apr 2010 - Dec 2011, and May-Sept 2018) 
• Senior Residency at Sir Ronald Institute of Tropical Medicine (Fever Hospital), Hyderabad (Aug 2015 – Aug 2016)
• Clinical Fellow at Krishna Institute of Medical Sciences, (Oct 2016 – Apr 2018)
• International training fellow at Leighton Hospital, Crewe, (Nov 2018 – Aug 2019)
• Clinical fellow at Wrightington Wigan and Leigh NHS Hospital Trust, (Aug 2019 – Aug 2021)
• Specialist Registrar – Rheumatology at Wrightington Wigan and Leigh NHS Hospital Trust, (Aug 2021- Feb 2022)