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Bromhexine Hydrochloride

Bromhexine is widely recognized as an active medication that can relieve respiratory discomfort. This article will discuss everything you need to know about it.

What is Bromhexine?

Bromhexine is a medicine used to thin out and break down excessive or thick mucus that gets clogged in the respiratory system. This process makes breathing easier for the patient. Mucus is a thin, clear liquid containing water, salts, and protective immune cells. When it becomes thick or excessive, it causes breathing difficulties, coughing, and congestion.

This medicine is usually available in dosage forms, tablet and oral suspension (syrup). 

Bromhexine Uses

Assisting the removal of excess mucus from airways. Doctors prescribe it for the following conditions:

  • Common cold - Bromhexine thins mucus, easing chest congestion, so coughing clears airways.
  • Respiratory infections like bronchitis and pneumonia - Bromhexine aids mucus expulsion, improving breathing and recovery.
  • Flu - Bromhexine is often combined with other medicines to manage chest congestion and cough.

Bromhexine also benefits chronic respiratory conditions, including COPD, emphysema, and asthma. It helps manage excessive mucus buildup.

Bromhexine Side Effects

Bromhexine treatment may cause unwanted effects. Though not everyone experiences them, some common bromhexine side effects that may occur include:

  • Feeling sick to the stomach
  • Throwing up
  • Loose, watery bowel movements
  • Sensations of spinning or whirling
  • Pain in the head region
  • Red, irritated skin rashes
  • Trouble inhaling and exhaling normally

Taking bromhexine requires extra caution for individuals with a history of stomach ulcers or digestive system issues. It could raise the likelihood of severe, unintended reactions occurring.

Precautions

Although bromhexine is typically safe, there are certain scenarios where caution must be taken:

  • If you're expecting or nursing, consult a doctor before using this medication. The benefits should outweigh the potential risks.
  • For those with liver or kidney issues, dosage adjustments may be required. Close monitoring is recommended, as bromhexine could worsen these conditions.
  • Dizziness is a possible side effect, so avoid operating vehicles or machinery while taking bromhexine.
  • This medicine isn't meant for long-term use beyond two weeks without medical supervision.

How to Use Bromhexine?

Bromhexine comes as tablets or oral liquid (syrup). The amount and way to take it could be different based on the form and your age or health issue. You must follow directions from your doctor or on the label very carefully.

  • For Bromhexine tablets, adults usually take one tablet three times each day.
  • For bromhexine oral liquid, the typical dose is 8-16 mg (2-4 teaspoonfuls), taken three to four times daily if you're an adult.

It's crucial to take Bromhexine exactly as instructed and never take more than the recommended amount unless your healthcare provider says it's okay.

How Does Bromhexine Work?

Bromhexine stimulates increased production of water secretions within our respiratory passages. This helps to break up and thin out stubborn, sticky mucus, making it easier to expel. Additionally, Bromhexine enhances the movement of tiny hair-like structures called cilia that line our airways. These actively whip and propel the thinned mucus outwards, promoting clear breathing.

  • Firstly, Bromhexine directly triggers the increased release of serous (watery) secretions. These aqueous fluids dilute the thick, viscous mucus, changing its consistency.
  • Simultaneously, it boosts ciliary activity - the rhythmic beating of thousands of microscopic cilia that coat the respiratory tract. This accelerated movement pushes the now-thinned mucus upwards, ready for effective coughing and clearance.
  • Furthermore, Bromhexine disrupts the intricate chemical bonds forming the mucus itself. By altering its molecular structure, the previously dense, sticky secretions become more easily dislodged and expellable.

Missed Dose

Quickly take it when you recall. But if it's nearly time for the next scheduled amount, don't take the missed dose. Just proceed with your regular dosing routine. Avoid doubling up doses to make up for a skipped one.

Overdose

If you accidentally take too much Bromhexine, immediately seek medical help. Call the poison control centre. Overdose symptoms can include vomiting, nausea, stomach pains, and trouble breathing.

Storage

Keep bromhexine at room temperature, shielded from excessive warmth, dampness, and direct sunshine. Store the medicine safely away from children and pets.

Bromhexine vs. Benadryl

Bromhexine and Benadryl (diphenhydramine) are two different medications used for different purposes:

Point

Bromhexine

Benadryl (Diphenhydramine)

Class of Drug

Mucolytic agent

Antihistamine

Primary Use

Thins and loosens mucus in the respiratory tract to aid in coughing and clearing airways

Treats symptoms of allergies such as sneezing, itching, and runny nose. Could even be used for a sedative.

Mechanism of Action

Increases production of serous (watery) secretions, enhances ciliary activity, and breaks down mucus structure

Blocks effects of histamine - substance that is produced by the body when an allergic reaction occurs.

Respiratory Use

Used in respiratory conditions involving excessive mucus production, such as colds, bronchitis, and COPD

Can provide relief from respiratory symptoms associated with allergies, such as nasal congestion and cough

Other Uses

Primarily used for respiratory conditions

Also used for insomnia, motion sickness, and as a mild sedative

Conclusion

Bromhexine helps people with lung issues involving too much mucus by thinning the mucus. This can ease chest stuffiness, coughing, and breathing troubles. But it's crucial to take bromhexine as directed by your doctor. Follow all safety guidance and dosing instructions carefully for best results.

FAQs

1. Can Bromhexine be used for dry cough? 

Bromhexine isn't suggested for dry coughs. Bromhexine's role involves thinning mucus and easing mucus clearance. Dry coughs may require different remedies or medicines.

2. Are Bromhexine and Ambroxol the same? 

Bromhexine and ambroxol aren't the same, yet they belong to mucolytic agents. Ambroxol is a metabolite of Bromhexine. Both help mucus thinning but are distinct compounds.

3. How do you take Bromhexine? 

Bromhexine comes as pills or liquid. To take pills, swallow one Bromhexine tablet three times daily. For liquid form, take two to four teaspoons of Bromhexine suspension three to four times per day. The dosage may vary, so carefully follow your doctor's advice or instructions on the medicine label.

4. When should Bromhexine not be used? 

People allergic to bromhexine or its inactive ingredients must avoid this drug. Use caution with ulcers, liver, or kidney diseases. Bromhexine— could worsen these conditions. Don't take Bromhexine for more than 14 days without a doctor's approval. Prolonged use may increase risks.