Prednisone

Prednisone

If your immune system is hyperactive, Prednisone, a corticosteroid medication, can help reduce inflammation and calm it down. Prednisone treats various illnesses, including asthma, arthritis, ulcerative colitis, chronic obstructive pulmonary disease, lupus, psoriasis, allergic diseases, skin issues, and Crohn's disease. Three different forms of Prednisone are available: tablets with an immediate release, delayed release, and liquid. Each of these dosages is consumed orally.

Prednisone works by reducing inflammation, calming a hyperactive immune system, or replacing cortisol that the body normally produces. The hormone cortisol is crucial to how the body reacts to stress, disease, and damage.

Prednisone is classified within the category of medications known as corticosteroids, frequently referred to as steroids. It is available in the form of immediate-release oral tablets that are ingested, which means the drug is rapidly released and absorbed by the body upon ingestion.

Prednisone brand-name versions

The immediate-release tablet form of prednisone is exclusively accessible in its generic version; no brand-name version is available.

What are the uses of Prednisone?

Prednisone often treats several illnesses, including rheumatoid arthritis, blood disorders, eye problems, severe allergies, breathing issues, skin diseases, cancer, and immune system abnormalities. Prednisone is a member of the corticosteroid medication class. It lessens the immune system's responsiveness to certain illnesses to lessen symptoms, including swelling and allergic-like responses.

How and when should I take Prednisone?

This medicine should be taken orally with a glass of water or milk. You can take this with meals. The prescription label's instructions should be followed. If you take the medication in liquid form, use a proper measuring device or spoon to accurately measure the dosage. Take this medication in the morning if you only take it once daily.

Your doctor will determine the amount and duration of your treatment based on your medical condition and how you respond to treatment. Avoid stopping this medication without first talking to your doctor. When this medication is abruptly discontinued, some problems may get worse. Symptoms including fatigue, weakness, weight loss, nausea, headaches, muscular pain, and dizziness may also appear.

What are the side effects of Prednisone?

Prednisone often has moderate side effects, especially when used in smaller doses and for a brief period. They could persist for a few days to a few weeks. Speak with your doctor if adverse symptoms intensify or persist.

Common side effects may include:

• Acne
• Changes in behaviour or mood
• Dizziness
• Vomiting
• Blurred vision
• Increased blood pressure 
• Increased blood sugar
• Increased appetite
• Trouble sleeping
• Fluid retention
• Restlessness and inability to stay still
• Thinning skin
• Weight gain

Prednisone's most severe side effects typically include allergic reactions, infections, digestive problems, and high blood sugar. This might happen if patients use the drug longer or in higher doses. Prednisone side effects can range in intensity and kind based on a person's overall health, age, and other medications they take. Women are more prone to encounter these adverse effects than males.

What precautions should be taken?

• If you have an allergy to Prednisone, any other drugs, or any inactive components in Prednisone tablets or solutions, let your doctor and chemist know immediately.
• Prednisone can keep you from experiencing symptoms if you have an infection while also decreasing your body's capacity to fight it. Avoid contact with sick people when taking this medicine, and do your best to keep your hands clean.
• If used longer, this medicine can retard a child's growth. To learn more, speak with your physician. Regular medical visits will allow the growth and height of your child to be monitored.
• This medicine may result in gastrointestinal bleeding. Alcohol use on a regular basis while taking this medication may raise your risk of stomach bleeding.
• During pregnancy, this drug should be taken only when necessary. It is quite unlikely to damage an unborn baby.
• Elderly people may be more vulnerable to this medication's adverse effects, including bone loss/pain, stomach/intestinal bleeding, and mental/emotional problems.

What happens If I miss a dose or take an overdose of Prednisone?

The missing dosage should be taken as soon as you recall. If the next dose is due, skip the missed dose. Do not double the dosage to make up for a missing one.

It is unlikely that a Prednisone overdose may result in fatal symptoms. However, long-term use of high steroid doses can result in side effects like menstrual concerns, impotence, or loss of interest in sex. Other symptoms include thinning skin, changes in the shape or location of body fat, easy bruising, increased acne or facial hair, and changes in the shape or location of your body hair. Seek medical help immediately.

What are the storage conditions for Prednisone?

• The drug needs to be stored in a secure container at room temperature, away from heat, moisture, and strong light.
• Prednisone solution should be discarded 90 days after the bottle is first opened.
• Keep out of children's reach.

What are the disposal methods for Prednisone?

Unused medications need to be disposed of safely to prevent pets, children, and others from accidentally taking them. It’s important not to flush these medications down the toilet, as this can harm the environment. The best way to get rid of your medication is to use a medicine take-back program, where you can return the drugs to a safe location for proper disposal. This helps ensure they won't pose a risk to anyone.

What special precautions should I follow?

Your doctor may advise you to follow a low-salt, high-potassium, or high-calcium diet. They might also prescribe or suggest a calcium or potassium supplement, so be sure to follow these instructions closely.

Discuss with your doctor whether you can eat grapefruit or drink grapefruit juice while taking this medication.

Who should not take Prednisone?

• People with Certain Infections: If you have systemic fungal infections or some viral infections, you should avoid prednisone.
• Those with Allergies: If you're allergic to prednisone or other similar medications, don't take it.
• Patients with Specific Health Issues:
  • Uncontrolled diabetes, as it can raise blood sugar levels.
  • High blood pressure, because it may worsen it.
  • Osteoporosis or weak bones, since it can decrease bone strength.
  • Active stomach ulcers, as it can increase the risk of ulcers.
• Pregnant or Breastfeeding Women: Use with caution; consult a doctor first.
• Individuals with Severe Mental Health Issues: Those with a history of mental health problems may experience worsened symptoms.

What can I do to stay healthy while taking Prednisone?

Your healthcare provider will consider the potential benefits and side effects when prescribing prednisone and other medications. Many people have successfully used prednisone without experiencing serious side effects. By following the prescribed instructions, and taking necessary precautions, you can gain the benefits of prednisone while managing any side effects. Here are some tips to help you stay healthy:

• Take your medication exactly as prescribed.
• Avoid taking double doses. Check with your healthcare provider on what to do if you miss a dose.
• Do not stop taking the medication without your healthcare provider's approval. Typically, the dose of prednisone is gradually reduced to prevent withdrawal symptoms, as stopping suddenly can lead to:
  • Fatigue
  • Significant mood changes
• Limit your intake of salt and sugar in your diet.
• Keep track of your weight.
• Contact your healthcare provider if you notice any sudden or unusual symptoms, such as dizziness, vision issues, shortness of breath, or an irregular heartbeat.

Caution with other medicine

Prednisone interacts with many medications and substances since it is a steroid. As a result, anyone on Prednisone must inform their doctors about all the medications they are currently taking. Prednisone has the following drug interactions:

• Oral Birth Control pill
• Antibiotic called fluoroquinolones
• Blood thinners
• Diabetes medicine
• Heart medications
• Antidepressants
• Ibuprofen and salicylates
• Corticosteroids
• Diuretics

Mild Interaction

• Antacids: These may reduce the effectiveness of prednisone if taken simultaneously. It's best to space them apart.
• Certain Antibiotics: Some antibiotics can interact with prednisone, potentially affecting its effectiveness.
• Blood Sugar Medications: Prednisone can increase blood sugar levels, so adjustments may be needed for diabetes medications.
• Vaccines: Live vaccines may be less effective when taking prednisone, and you may be at increased risk for infections.
• Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Using NSAIDs with prednisone can increase the risk of gastrointestinal issues.

How quickly does Prednisone show results?

It may take a few days to fully experience the effects of Prednisone. However, it should begin to act within a few hours.

When should I contact the doctor for side effects?

You should contact your doctor for side effects of prednisone if you experience:

• Severe Mood Changes: Such as extreme anxiety, depression, or mood swings.
• Signs of Infection: Fever, chills, or persistent sore throat.
• Unusual Weight Gain: Rapid weight gain or swelling in the face, hands, or feet.
• Gastrointestinal Issues: Severe stomach pain, nausea, or vomiting.
• Changes in Vision: Blurred vision or other visual disturbances.
• Skin Reactions: Rash, itching, or unusual bruising.
• Difficulty Breathing: Shortness of breath or chest pain.
• Severe Fatigue: Extreme tiredness or weakness that doesn’t go away.

Prednisone vs Celebrex

FAQs

1. What is the difference between Prednisone and COX-2?

Prednisone is a corticosteroid used to suppress the immune system and reduce inflammation. CCOX-2 is a nonsteroidal anti-inflammatory drug (NSAID) primarily used to relieve pain and inflammation.

2. How long do you use prednisone?

The duration of prednisone use varies depending on the medical condition being treated. It can be short-term for acute issues or longer-term for chronic conditions, under a doctor's supervision.

3. Is prednisone safe for kidneys?

Prolonged use of prednisone can have adverse effects on the kidneys. It's crucial to use it as prescribed and monitor kidney function with a healthcare provider.

4. When should I take prednisone?

Prednisone dosing instructions, including timing, depend on the condition being treated. Follow your healthcare provider's guidance for the most appropriate timing.

5. Is prednisone a painkiller?

Prednisone is not a painkiller but a corticosteroid that reduces inflammation. It may indirectly alleviate pain caused by inflammation but does not primarily target pain relief.

6. Can prednisone cause shortness of breath?

Shortness of breath is a potential side effect of prednisone, particularly when used in higher doses or for extended periods. If you experience this, consult your doctor promptly to adjust the treatment plan.

7. What is the biggest side effect of prednisone?

The most significant side effects of prednisone can include weight gain, high blood pressure, osteoporosis, and an increased risk of infections. Long-term use may also lead to diabetes, mood swings, and gastric ulcers.

8. Is prednisone a powerful steroid?

Yes, prednisone is a potent corticosteroid used to reduce inflammation and suppress the immune system. It is often used to treat various conditions like autoimmune diseases, allergies, and inflammatory conditions.

9. Who cannot take prednisone?

Prednisone should be avoided by individuals with certain conditions such as active infections, untreated fungal infections, peptic ulcer disease, or certain types of liver diseases. It's also used cautiously in people with diabetes, high blood pressure, and osteoporosis.

10. What to avoid while taking prednisone?

While on prednisone, it is advised to avoid alcohol, as it can increase the risk of gastrointestinal bleeding. Additionally, you should avoid live vaccines, as prednisone can weaken your immune response. It's also important to limit sodium intake to prevent fluid retention and high blood pressure.

11. Is prednisone used for sinus infection or cough?

Prednisone may be used for severe sinus infections or persistent coughs, particularly when inflammation is a significant component of the condition. However, it is not typically the first-line treatment and should be used under the guidance of a healthcare provider.

12. When should prednisone be used?

Prednisone should be used when prescribed by a healthcare provider for specific conditions where its anti-inflammatory and immunosuppressive effects are needed. It is commonly used for conditions like arthritis, lupus, asthma, and certain allergies.

13. Is prednisone a painkiller?

Prednisone is not a painkiller in the traditional sense. It reduces inflammation, which can help relieve pain indirectly, but it is not specifically designed to manage pain like analgesics or opioids.

14. Is prednisone safe for kidneys?

Prednisone can have an impact on kidney function, especially with long-term use or in high doses. It can lead to fluid retention and high blood pressure, which can affect the kidneys. Regular monitoring of kidney function is advisable while on prednisone.

References:

https://www.webmd.com/drugs/2/drug-6007-9383/Prednisone-oral/Prednisone-oral/details https://www.drugwatch.com/Prednisone/
https://www.drugs.com/Prednisone.html#dosage
https://medlineplus.gov/druginfo/meds/a699022.html

Disclaimer: The information provided here is not meant to substitute an advice from a healthcare professional. The information is not intended to cover all the possible uses, side-effects, precautions, and drug interactions. This information is not intended to suggest that using a specific drug is suitable, safe, or efficient for you or anyone else. The absence of any information or warning regarding the drug should not be interpreted as an implicit guarantee from the organisation. We strongly advise you to consult a doctor if you have any concerns about the drug and never use the medication without a doctor’s prescription.