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Metoprolol

Metoprolol is a powerful medication prescribed to treat high blood pressure in patients. This drug is made up of two active components, Metoprolol Tartrate and Metoprolol Succinate, both known for their effectiveness in controlling blood pressure. By relaxing the blood vessels and slowing down the heart rate, Metoprolol improves blood circulation and decreases blood pressure levels. The use of Metoprolol can provide significant benefits for those with hypertension, making it an important medication for managing this condition.

How Does Metoprolol Work?

Metoprolol works by blocking the action of certain hormones, such as adrenaline, that affect the heart and blood vessels. By doing so, it reduces the heart rate and the force with which the heart pumps blood. This results in a decrease in blood pressure and less strain on the heart.

What are the uses of Metoprolol?

Metoprolol is a medication that is commonly used to treat heart-related pain, improve blood flow and pressure. It is also used to treat irregular heartbeat, prevent future heart attacks, heart diseases, or stroke, reduce symptoms of too much thyroxine accumulation, and slow down heart rate, which can help the heart pump blood efficiently. Additionally, Metoprolol is prescribed during migraine headaches.

How and when to take Metoprolol?

Metoprolol is available in two forms: normal tablet and extended-release tablet, which works for a longer time. The dosage of the tablet depends on the number of doses prescribed by the doctor. You can take it before or after each meal, but the extended tablet should only be taken once a day. As Metoprolol alters heart rates and blood vessels, it should not be taken in greater or lesser amounts than prescribed by the doctor. It is crucial not to change the dose of Metoprolol on your own, and always consult with your doctor if you need a change in the dose prescribed earlier.

What are the side effects of Metoprolol?

This drug may cause some metoprolol side effects, as listed below:

  • Dizziness
  • Stomach aches
  • Vomiting
  • Tiredness
  • Gas in stomach
  • Rash
  • Runny nose
  • Depression
  • Constipation
  • Fainting

Some of these side effects may be serious, and you should call your doctor if you feel any of them for a prolonged time or if they become too severe.

What precautions should be taken?

While taking the dose of this drug, take care of the following precautions:

  • While consulting your doctor, you should inform them if you are allergic to Metoprolol, acebutolol, atenolol, bisoprolol, timolol, betaxolol, esmolol, labetalol, sotalol, nadolol, carvedilol, pindolol, propranolol, or any other ingredients of Metoprolol tablets.
  • Tell your doctor and pharmacist what medicines (prescription and non-prescription) you have taken before. Be sure to mention if you take or plan to take the following: vitamins, nutritional supplements, herbal products, fluoxetine, paroxetine, etc.
  • Inform the doctor if you have had any lung diseases, asthma, heart or liver diseases, diabetes, overactive thyroid glands, or allergies. 
  • Inform your doctor if you suffer from slow heart rates or pheochromocytoma (a tumour of a gland near the kidney). Owing to these problems, the doctor may tell you whether or not to take Metoprolol.

What if you miss the dose of Metoprolol?

If you miss a dose of Metoprolol, you can take the missed dose as and when you remember it, but you can skip it if it is time for the next dose. It is advised to ask your doctor beforehand about such a situation. 

What if you take an overdose of Metoprolol?

Taking an overdose of Metoprolol can lead to difficulty breathing, slowing heartbeats, etc. In some cases, it may lead to Myocardial depression and Cardiovascular collapse. 

What are the storage conditions for Metoprolol?

  • This drug should be stored at room temperature. Keep it between 15 -30C (59 - 86F).

  • Store medication in original packaging, out of reach of children, and in a dry location.

Caution with other medicines

The following medicines may interfere with Metoprolol.

  • Monoamine Oxidase Inhibitors (MAOIs)
  • Antidepressants
  • Diphenhydramine
  • Digoxin
  • Clonidine

How quickly does Metoprolol show results?

Metoprolol typically begins working within two hours and reaches its full effect after about a week. It's normal to not feel any immediate changes in the body, but this doesn't indicate that the medication isn't effective.

Comparison of a Metoprolol medicine with a Carvedilol 

 

Metoprolol

Carvedilol

Composition

Metoprolol is made of Metoprolol tartrate and Metoprolol succinate.

Carvedilol is made up of Carvedilol phosphate. 

Uses

It mainly relieves a patient from angina pectoris (chest pain) and high blood pressure, manages heart attacks, prevents migraines, etc.

It also relieves a patient from angina pectoris and high blood pressure, manages heart attacks, prevents migraines, etc. However, since it is a more potent drug, it is advised to take it only when prescribed.

Side Effects

  • Fatigue
  • Dizziness
  • Shortness of breath
  • Insomnia
  • Headache
  • Irregular or slow heartbeats
     
  • Cold hands or feet
  • Dry mouth
  • Diarrhoea 
  • Constipation
  • Nausea 
  • Vomiting
     

Both Metoprolol and Carvedilol work almost similarly and against similar diseases. The only difference is that Metoprolol is often a better choice if you have an abnormal heart rhythm or asthma. Carvedilol makes a great choice if you have weakened heart muscles.

FAQs

1. What is Metoprolol, and what is its primary purpose?

Metoprolol is a medication classified as a beta-blocker. It is primarily prescribed to treat conditions related to the heart and blood vessels, including hypertension (high blood pressure), angina (chest pain), heart failure, and certain heart rhythm disorders.

2. Are there different formulations of Metoprolol available?

Yes, Metoprolol comes in various formulations, including immediate-release tablets and extended-release capsules. The choice of formulation depends on your condition and the desired duration of action.

3. Are there common side effects associated with Metoprolol?

Common side effects may include fatigue, dizziness, slow heart rate, and cold extremities. These side effects can vary in intensity and impact individuals differently.

4. Can Metoprolol interact with other medications or substances?

Yes, Metoprolol may interact with other medications, including other blood pressure-lowering drugs and certain antidepressants. It is important to inform your healthcare provider about all the medications, supplements, and substances you are taking to avoid potential interactions.

5. Can Metoprolol be used to treat conditions other than heart-related issues?

While Metoprolol is primarily prescribed for heart-related conditions, it may also be prescribed to manage other conditions, such as migraine prevention and anxiety.

References:

https://www.nhs.uk/medicines/Metoprolol/#:~:text=Metoprolol%3A%20medicine%20for%20high%20blood%20pressure%20(hypertension)%20%2D%20NHS https://pubmed.ncbi.nlm.nih.gov/25908023/#:~:text=Metoprolol%20is%20a%20moderately%20lipophilic,the%20potential%20for%20cardiovascular%20collapse
https://www.goodrx.com/Metoprolol/interactions

Disclaimer: The information provided here is not meant to substitute an advice from a healthcare professional. The information is not intended to cover all the possible uses, side-effects, precautions, and drug interactions. This information is not intended to suggest that using a specific drug is suitable, safe, or efficient for you or anyone else. The absence of any information or warning regarding the drug should not be interpreted as an implicit guarantee from the organisation. We strongly advise you to consult a doctor if you have any concerns about the drug and never use the medication without a doctor’s prescription.