Nimesulide

Nimesulide

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) having analgesic and antipyretic effects that are primarily COX-2 selective. This medication is used to relieve pain. It relieves mild to moderate pain caused by menstrual cramps and osteoarthritis in adults and teenagers over the age of 12. Nimesulide reduces the intensity of pain signals transmitted to the brain and also prevents the synthesis of prostaglandins (substances that relay pain and heat signals to the brain).

What are the uses of Nimesulide?

When there are joint problems, such as arthritis, Nimesulide is used to reduce pain, swelling, and inflammation. Moreover, it eases pain from surgery, dental pain, mild sprains and strains, and ear, nose, and throat pain. In addition, it is used to treat osteoarthritis and menstrual cramps that are extremely painful. Moreover, it alleviates mild to severe pain brought on by muscle and joint sprains and strains. But children under 12 shouldn't use Nimesulide, as it carries a serious risk of liver damage.

How and when to take Nimesulide?

Nimesulide is available in various forms, including tablets, syrup, capsules, tablet DT, tablet MD, injectables, oral drops, solutions, and gel. After examining your medical condition, your doctor will choose the best dosage form and amount for the medication. At the hospital, your doctor can provide Nimesulide injectables.

Take your tablet or capsule with water and take it whole. Never eat, break, or crush it. If the tablet is mouth-dissolving, place it on your tongue. Allow it to dissolve or fall apart. Before swallowing, the tablet should thoroughly dissolve in your mouth. Before using a dispersible pill, read the label. Dissolve the pill in the required amount of water and drink the contents. Shake the suspension bottle carefully before using it. Take the specified amount by mouth using the measuring cup/dropper included in the package.

What are the side effects of Nimesulide?

Nimesulide should be taken only under the supervision of a qualified medical professional. Long-term usage may harm the liver or result in significant side effects, including gastrointestinal bleeding or renal issues. Some significant adverse effects of Nimesulide are:

• Acid or sour stomach
• Dizziness
• Stomach pain and cramps
• Skin infection
• Increased liver enzymes
• Nausea and vomiting
• Diarrhoea
• Blood clotting problems

If you have any noticeable symptoms, speak with your doctor immediately for guidance. Nonetheless, if you have any side effects from Nimesulide, stop taking it. The positives of this medication outweigh the adverse effects. Thus a doctor may suggest you use it after assessing your condition. Many of those who use this medication don't experience any negative effects. However, get quick medical attention if you experience any severe Nimesulide side effects.

What precautions should be taken?

• Ask your doctor before using Nimesulide if you have any drug allergies or are allergic to any other substances. The product can have inactive substances that cause allergic reactions or other severe issues.
• Nimesulide is not advised for alcoholism, drug addiction, or coagulation issues, in children, during pregnancy, or in nursing mothers.
• If you have asthma, a recent heart bypass surgery, heart disease, an active stomach ulcer, recent gastrointestinal bleeding, a history of an allergy to any medications, or any of these conditions, please let your doctor know before taking Nimesulide.
• Nimesulide tablets may result in lightheadedness or eyesight problems. After taking this medication, avoid engaging in activities like operating a machine or driving a car.
• Stop using this medication only after talking to your doctor. Any adverse effects after taking it should be reported to your doctor.

What if I miss the dose or overdose on Nimesulide?

Your body won't be affected if you miss one or two doses of Nimesulide. The missed dosage has no adverse effects. In some circumstances, if you miss a dosage, your doctor may encourage you to take the recommended medication as soon as possible unless it is already time for the next dose.

Accidental drug overdoses are possible. There is a possibility that taking more Nimesulide pills than recommended will harm your body. A medication overdose may result in a medical emergency. Contact your doctor or nearest hospital in such a situation.

What are the storage conditions for Nimesulide?

• The medication should be stored at room temperature, between 20 and 25C (68 and 77F).
• Keep this medication in a cool, dry environment and the original box or container until it is time to take it.
• Keep this medicine out of kids' reach and sight.

Caution with other medicine 

Nimesulide may interact with medications for the respiratory system, blood thinners, antidiabetics (insulin), anti-epileptics, anti-cancer agents, drugs that influence the immune system, antacids, and anti-HIV medications (didanosine). Avoid consuming dairy products like milk, yoghurt, or drinks with added calcium.

How quickly does Nimesulide show results?

Within 15 minutes of taking the medication, Nimesulide significantly relieves pain and inflammation.

Comparison of a Nimesulide medicine with an Aceclofenac

FAQs

1. What is Nimesulide used for?

Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and acute pain.

2. How does Nimesulide work?

Nimesulide works by inhibiting the production of certain substances (prostaglandins) that contribute to pain and inflammation in the body.

3. Can I take Nimesulide with food?

Nimesulide can be taken with or without food. However, taking it with food may help reduce the risk of stomach upset.

4. What are the common side effects of Nimesulide?

Common side effects may include stomach pain, nausea, indigestion, and dizziness. Serious side effects can occur, so it's important to report any unusual symptoms to your healthcare provider.

5. Can Nimesulide be used for fever?

Nimesulide has anti-inflammatory properties and can be used to reduce fever along with treating pain and inflammation. However, it's essential to follow the recommended dosage and consult with a healthcare professional.

References:

https://www.ncbi.nlm.nih.gov/books/NBK547948/#:~:text=Nimesulide%20is%20generally%20well%20tolerated,peripheral%20edema%20and%20hypersensitivity%20reactions. https://www.ncbi.nlm.nih.gov/books/NBK547948/

Disclaimer: The information provided here is not meant to substitute an advice from a healthcare professional. The information is not intended to cover all the possible uses, side-effects, precautions, and drug interactions. This information is not intended to suggest that using a specific drug is suitable, safe, or efficient for you or anyone else. The absence of any information or warning regarding the drug should not be interpreted as an implicit guarantee from the organisation. We strongly advise you to consult a doctor if you have any concerns about the drug and never use the medication without a doctor’s prescription.