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Diclofenac+Paracetamol+Serratiopeptidase

Diclofenac+Paracetamol+Serratiopeptidase is a pharmaceutical combination used to treat pain and inflammation in illnesses such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, and post-operative pain. The medication contains Diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, Paracetamol, which is an analgesic that relieves pain and fever, and Serratiopeptidase, which is an enzyme that reduces swelling and improves tissue healing.

What are the uses of Diclofenac+Paracetamol+Serratiopeptidase?

Diclofenac+Paracetamol+Serratiopeptidase is a combination of three regularly used pain and inflammatory drugs. Below are a few of the applications for this drug pointwise:

  • Pain relief
  • Inflammation
  • Swelling
  • Fever
  • Respiratory infections
  • Sinusitis
  • Dental pain

It should be noted that this drug must be used as suggested by a medical professional and not as a form of self-medication.

Benefits of using Diclofenac+ Paracetamol+ Serratiopeptidase tablets

The combination of Diclofenac, Paracetamol, and Serratiopeptidase in tablets offers several benefits:

  • Pain Relief: Diclofenac and Paracetamol are effective in relieving various types of pain, including joint pain, muscle pain, back pain, dental pain, and pain associated with inflammation.
  • Anti-inflammatory Action: Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce inflammation, swelling, and stiffness in joints and muscles. This can be particularly beneficial for conditions like arthritis.
  • Fever Reduction: Paracetamol (also known as acetaminophen) helps in reducing fever associated with infections or inflammatory conditions.
  • Enzymatic Action: Serratiopeptidase, a proteolytic enzyme, is believed to have anti-inflammatory properties and may help in reducing swelling and promoting tissue healing. It can aid in improving symptoms related to inflammation and injuries.
  • Comprehensive Relief: The combination of these three components in a single tablet provides comprehensive relief by targeting different pathways involved in pain and inflammation. This can result in quicker and more effective relief compared to using each medication alone.
  • Convenience: Using a combination tablet simplifies medication regimen, reducing the number of pills to be taken and potentially improving compliance with treatment. 

How and when to take Diclofenac+Paracetamol+Serratiopeptidase?

Diclofenac+Paracetamol+Serratiopeptidase is a medication that relieves pain, reduces inflammation, and treats respiratory infections and sinusitis. It is typically used either with or without meals, and the amount and duration of medication may vary based on the ailment being treated. It should not be mashed, chewed, or broken and should be consumed entirely with water. It is critical to follow your healthcare professional's directions or medication label. Inform them about any other medications or medical conditions, and do not exceed the recommended dosage or duration of treatment.

What are the side effects of Diclofenac+Paracetamol+Serratiopeptidase?

There could be some common side effects of Diclofenac+Paracetamol+Serratiopeptidase, such as

  • Nausea and vomiting
  • Diarrhoea or constipation
  • Stomach pain or discomfort
  • Headache
  • Dizziness or lightheadedness
  • Skin rash or itching
  • Increased risk of bleeding
  • Allergic reactions such as swelling, difficulty breathing, and hives
  • Liver damage in rare cases

Usually, the side effects go away after some time. But if the symptoms are worsening, you should see your doctor.

What precautions should be taken?

Notify your physician if you are allergic to the medicine. Even if you are allergic to other medicines, you should discuss them with your doctor.

  • If you are pregnant or nursing, tell your doctor since the adverse effects of this medicine while pregnant and nursing have not been proven.
  • Inform your healthcare professional if you have a history of stomach ulcers, bleeding disorders, liver or kidney disease, asthma, or other medical conditions.
  • Do not take this medication with alcohol because it raises the likelihood of liver failure.
  • Do not exceed the duration of treatment or the recommended dosage, as it can lead to side effects.
  • If you are intolerant to this drug, do not take it.
  • If you have any unexpected symptoms, such as stomach pain, nausea, vomiting, skin rash, or difficulty breathing, seek medical attention immediately.

What if I missed the dose of Diclofenac+Paracetamol+Serratiopeptidase?

If you miss a dose of Diclofenac+Paracetamol+Serratiopeptidase, you can take it when you remember. If the next dose is due sometime soon, then you should skip the missed dose. Taking a double dose to make up for the missed dose is not recommended.

What if there is an overdose of Diclofenac+Paracetamol+Serratiopeptidase?

An overdose of Diclofenac+Paracetamol+Serratiopeptidase can be harmful and may cause serious side effects. Symptoms may include nausea, vomiting, stomach pain, diarrhoea, dizziness, drowsiness, confusion, difficulty breathing, and seizures. Seek medical attention immediately and do not exceed the recommended dosage.

What are the storage conditions for Diclofenac+Paracetamol+Serratiopeptidase?

  • Diclofenac+Paracetamol+Serratiopeptidase should be stored at room temperature (below 30C) and away from direct sunlight and moisture.
  • Keep it away from children and pets.
  • Do not consume after the expiration date.

Caution with other medicine

Diclofenac+Paracetamol+Serratiopeptidase may interact with other medications, affecting how they work and increasing the risk of side effects. Inform your doctor if you have ongoing prescriptions, including over-the-counter medications, vitamins, or herbal supplements. In addition, avoid taking this medication with other nonsteroidal anti-inflammatory drugs (NSAIDs) or blood thinners, as it can increase the risk of bleeding.

Who should not take Diclofenac+ Paracetamol+ Serratiopeptidase tablets? 

Diclofenac, paracetamol, and serratiopeptidase tablets may not be suitable for certain individuals due to various reasons. Here are some considerations on who should not take these tablets:

  • Allergy or Hypersensitivity: Individuals with a known allergy or hypersensitivity to diclofenac, paracetamol, serratiopeptidase, or any other ingredients in the tablets should avoid taking them.
  • History of Gastric Ulcers or Bleeding Disorders: Diclofenac, as an NSAID, can increase the risk of gastric ulcers and gastrointestinal bleeding. Individuals with a history of stomach ulcers, bleeding disorders, or gastrointestinal bleeding should avoid diclofenac-containing medications.
  • Severe Kidney or Liver Disease: Diclofenac and paracetamol are metabolized in the liver and excreted by the kidneys. Individuals with severe kidney disease or liver disease may require dose adjustments or avoidance of these medications due to potential adverse effects on these organs.
  • Pregnancy and Breastfeeding: Pregnant or breastfeeding women should use these medications with caution and under medical supervision, as some components may pose risks to the developing fetus or nursing infant.
  • Children: The safety and efficacy of diclofenac, paracetamol, and serratiopeptidase tablets in children below a certain age (typically under 18 years) may not be established. Pediatric dosing should be carefully monitored and prescribed by a healthcare professional.
  • History of Cardiovascular Disease: NSAIDs like diclofenac may increase the risk of cardiovascular events such as heart attack or stroke, particularly in individuals with pre-existing cardiovascular disease or risk factors.
  • Asthma: Some individuals with asthma may be sensitive to NSAIDs and could experience exacerbation of asthma symptoms upon taking diclofenac-containing medications.

How quickly does Diclofenac+Paracetamol+Serratiopeptidase show results?

Diclofenac+Paracetamol+Serratiopeptidase is a fast-acting medication, and some people may notice a reduction in their symptoms within a few hours after taking the medication.

Dosage for Diclofenac+ Paracetamol+ Serratiopeptidase Tablets

The dosage for Diclofenac + Paracetamol + Serratiopeptidase tablets can vary depending on factors such as the specific formulation, the severity of the condition being treated, and the individual patient's medical history. 

Age Group

Drug

Dosage

Adults

Diclofenac

50 mg

Elderly

Paracetamol

325 mg

Pediatric

Serratiopeptidase

10 mg

Comparison of a Diclofenac+Paracetamol+Serratiopeptidase combination medicine with an Esgipyrin SP

 

Diclofenac+Paracetamol+Serratiopeptidase

Esgipyrin SP

Composition

Diclofenac+Paracetamol+Serratiopeptidase contains:

  • Diclofenac sodium (a nonsteroidal anti-inflammatory drug).
  • Paracetamol (an analgesic and antipyretic).
  • Serratiopeptidase (an enzyme that breaks down proteins).

Esgipyrin SP contains aspirin (a nonsteroidal anti-inflammatory drug), Paracetamol, and caffeine.

Uses

Diclofenac+Paracetamol+Serratiopeptidase is primarily used to manage pain and inflammation in conditions like arthritis, postoperative pain, and dental pain.

Esgipyrin SP relieves pain associated with headaches, menstrual cramps, toothache, and fever.

Side Effects

Diclofenac+Paracetamol+Serratiopeptidase may cause side effects like nausea, vomiting, stomach pain, dizziness, and allergic reactions.

Esgipyrin SP may cause side effects like stomach pain, heartburn, nausea, dizziness, and allergic reactions.

FAQs

1. What is the combination of Diclofenac, Paracetamol, and Serratiopeptidase used for?

This combination is often prescribed for the relief of pain and inflammation. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID), Paracetamol provides analgesic (pain-relieving) effects, and Serratiopeptidase is an enzyme with anti-inflammatory properties.

2. How does the combination work?

Diclofenac reduces inflammation by inhibiting the production of prostaglandins, Paracetamol relieves pain and reduces fever, while Serratiopeptidase helps to break down and remove inflammatory byproducts.

3. What conditions is the combination used to treat?

This combination is commonly used to manage pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, dental pain, and postoperative pain.

4. Can I take Diclofenac, Paracetamol, and Serratiopeptidase together?

Yes, these medications are often prescribed together in a fixed-dose combination for enhanced pain relief. However, it's crucial to follow your healthcare provider's instructions and not self-prescribe.

5. What are the common side effects of the combination?

Common side effects may include gastrointestinal discomfort, nausea, and headache. If you experience severe or persistent side effects, contact your healthcare provider.

6. Is diclofenac sodium and paracetamol an antibiotic?

No, diclofenac sodium and paracetamol are not antibiotics. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation, while paracetamol (acetaminophen) is a pain reliever and fever reducer. They work differently from antibiotics, which are used to treat bacterial infections.

7. Does Diclofenac+Paracetamol+Serratiopeptidase cause kidney damage?

The combination of diclofenac, paracetamol, and serratiopeptidase can potentially cause kidney damage, especially in individuals with pre-existing kidney conditions or when used at high doses or for prolonged periods. It's important to use these medications under medical supervision and follow the prescribed dosage to minimize the risk of kidney-related side effects.

8. Can Diclofenac+Paracetamol+Serratiopeptidase be taken with Vitamin B-complex?

Generally, there are no known significant interactions between diclofenac, paracetamol, serratiopeptidase, and vitamin B-complex supplements. However, it's always advisable to consult a healthcare professional before combining medications or supplements to ensure safety and avoid potential interactions.

9. Can you take Diclofenac and Paracetamol together?

Diclofenac and paracetamol can be taken together, but it's important to follow medical advice regarding dosage and duration of use. These medications have different mechanisms of action and can complement each other in providing relief from pain and inflammation. However, combining them should be done under medical supervision to monitor for potential side effects, especially related to gastrointestinal or kidney health.

References:

https://www.medicines.org.uk/emc/product/5909/smpc. https://www.drugs.com/search.php?searchterm=Diclofenac%2C+Paracetamol+and+Serratiopeptidase

Disclaimer: The information provided here is not meant to substitute an advice from a healthcare professional. The information is not intended to cover all the possible uses, side-effects, precautions, and drug interactions. This information is not intended to suggest that using a specific drug is suitable, safe, or efficient for you or anyone else. The absence of any information or warning regarding the drug should not be interpreted as an implicit guarantee from the organisation. We strongly advise you to consult a doctor if you have any concerns about the drug and never use the medication without a doctor’s prescription.