Serrapeptase  

Serrapeptase, or Serratiopeptidase, is an enzyme isolated from bacteria found in the digestive tract of silkworms. It has been traditionally used in Japan and

Europe to reduce inflammation and pain due to trauma, surgery, or other inflammatory conditions. However, Serrapeptase is widely used as a supplement for several health conditions. 

Serrapeptase is a proteolytic enzyme that breaks down proteins into smaller components called amino acids. According to research, Serrapeptase is more effective at improving lockjaw than corticosteroids and ibuprofen to treat inflammation.

How Does Serrapeptase Work?

Serrapeptase is known for its ability to break down and digest protein molecules. This enzymatic action allows it to support various physiological processes within the body. Here's how it works:

• Anti-Inflammatory: Serrapeptase is a powerful anti-inflammatory agent. It can help reduce inflammation by breaking down inflammatory proteins, which may alleviate symptoms associated with conditions like arthritis, sinusitis, and swelling.
• Mucus Thinning: This enzyme can also help thin mucus, making it easier for individuals with respiratory issues to breathe more comfortably. It's often used as a natural remedy for conditions like chronic obstructive pulmonary disease (COPD) and bronchitis.
• Pain Management: Serrapeptase may help reduce pain by decreasing inflammation and promoting tissue repair. This has led to its use in managing pain associated with conditions like fibromyalgia and sports injuries.

What are the uses of Serrapeptase? 

Serrapeptase treats conditions such as osteoarthritis, rheumatoid arthritis, back pain, and any condition causing pain. It also treats inflammation and mucus. It is prescribed only by healthcare professionals such as dieticians or pharmacists. 

Some doctors prescribe Serrapeptase to minimize pain and swelling post-oral surgery. It also alleviates common upper respiratory tract symptoms such as pain and inflammation. Apart from these, it also treats the following -   

• Arthritis
• Fibrocystic breast disease
• Oedema
• Ulcerative colitis.

How and when to use Serrapeptase?

When taken orally, it is easily dissolved and destroyed by your stomach acid before it reaches the intestine to be absorbed. For this reason, the dietary supplements of Serrapeptase are enteric-coated. This prevents the tablets or capsules from dissolving completely before reaching the intestines. The typical dosage of Serrapeptase is around 10 mg.

Also, you must take it on an empty stomach or 30 minutes before eating. You can also take it 2 hours after having your meal. The recommended dose for adults is 5-10 mg 3 times a day. Do not give the medicine to children, as there is no scientific evidence for usage by children. 

What are the side effects of Serrapeptase?

There are several side effects of taking Serrapeptase, such as -

• Skin irritation or dermatitis
• Erythema or rashes
• Joint pain
• Nausea
• Cough
• Blood clotting disturbance
• Poor appetite
• Muscle pain

If you experience any conditions after using Serrapeptase, stop using it instantly. Also, let your doctor know about the side effects. They might alter the dosage for you. Sometimes, it can also cause Stevens-Johnson Syndrome. It is characterized by large blisters and shedding of skin. In addition, there have been reports of lung inflammation (pneumonitis) and blood-clotting abnormalities.

What precautions should be taken?

Serrapeptase is usually considered safe. However, some people must avoid taking it -     

• It is not safe for children or people who are pregnant or breastfeeding. As little information is available, informing the doctor about your pregnancy is better. 
• People with blood clotting disorder should avoid Serrapeptase, as it can potentially disrupt normal blood clotting. Also, at times, Serrapeptase can make bleeding worse. 
• Do not take Serrapeptase before or after surgery, as it might increase bleeding. It is advisable to stop using the medicine 2 weeks before the surgery.

Do not take or stop taking medicine without consulting your doctor to avoid side effects. 

What if I missed the dose of Serrapeptase?

If you miss the dose of Serrapeptase, take it as soon as you remember. However, do not take it if your next dose is after 2-3 hours. Also, avoid doubling the dose to make up for the missed one.

What if there is an overdose of Serrapeptase?

Serrapeptase is considered safe for many people. Thus, there are fewer chances of an overdose. However, it is important to follow the doctor's advice on dosage. In case of an overdose, seek medical help immediately.

What is the storage condition for Serrapeptase? 

It is best to store Serrapeptase at room temperature. Keep the medicine away from direct sunlight, heat, and moisture. Do not store the drug in the bathroom or deep freeze it, as it might damage the effectiveness of the drug. It is always beneficial to check the packaging to get a clear idea of how to store Serrapeptase at home. 

Also, do not flush down your medicine or pour them into the drain. Instead, discard these medicines properly when they expire or are no longer used. 

Caution with medicines

If used with other drugs, Serrapeptase might change how your drug works or increase the chance of side effects. At the time of the doctor's consultation, tell them about all the medicines you are currently taking. 

Avoid taking Serrapeptase with blood thinners such as Warfarin and Aspirin. Also, avoid taking it with other dietary supplements such as fish oil, garlic, and turmeric. This might increase the risk of bleeding or bruising. Some of the other products that might interact with Serrapeptase are- 

• Fibrinolytic
• Antiplatelets or thrombolytics
• Anticoagulants 
• NSAIDs
• Other blood thinners.

How quickly does Serrapeptase show results?

Serrapeptase usually shows results in 4 weeks. 

Comparison of a Serrapeptase combination with a Serratiopeptidase

Serrapeptase is used to alleviate pain and swelling during oral surgeries. Apart from this, it can also eliminate common upper respiratory tract symptoms such as inflammation and pain. However, like any other drugs, Serrapeptase also has some side effects. Thus, it is important to take the medicine as and when prescribed by your healthcare provider. 

FAQs

1. What are the potential benefits of Serrapeptase?

Some potential benefits of Serrapeptase include reducing inflammation, relieving pain, supporting the respiratory system, and promoting wound healing.

2. Is Serrapeptase safe to use?

Serrapeptase is generally considered safe when used as directed. However, it may interact with certain medications, so it's important to consult with a healthcare professional before using it.

3. Can Serrapeptase be used for pain relief?

Serrapeptase is sometimes used as a natural pain reliever, particularly for conditions involving inflammation and tissue damage.

4. What conditions can Serrapeptase potentially help with?

Serrapeptase is often used to support conditions like arthritis, sinusitis, bronchitis, and postoperative recovery.

5. Are there any side effects associated with Serrapeptase?

Serrapeptase is generally well-tolerated, but some people may experience mild side effects like digestive issues or allergic reactions. Discontinue use if you experience adverse effects.

References

​https://www.yashodahospitals.com/medicine-faqs/Serrapeptase  /#:~:text=When%20taken%20as%20a%20supplement,see%20results%20in%204%2Dweeks. https://www.verywellhealth.com/Serrapeptase  -89513#toc-uses-of-Serrapeptase   https://www.webmd.com/vitamins/ai/ingredientmono-1115/Serrapeptase  #:~:text=Serrapeptase  %20is%20a%20chemical%20taken,classified%20as%20a%20dietary%20supplement.

Disclaimer: The information provided here is not meant to substitute an advice from a healthcare professional. The information is not intended to cover all the possible uses, side-effects, precautions, and drug interactions. This information is not intended to suggest that using a specific drug is suitable, safe, or efficient for you or anyone else. The absence of any information or warning regarding the drug should not be interpreted as an implicit guarantee from the organisation. We strongly advise you to consult a doctor if you have any concerns about the drug and never use the medication without a doctor’s prescription.