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Oral Cancer: Importance of Early Diagnosis and Treatment


Oral Cancer: Importance of Early Diagnosis and Treatment

Oral cancer is a type of cancer which falls in the category of head and neck cancer (HNC). It comprises diverse tumor types arising from different anatomic structures such as oropharynx, oral cavity, hypopharynx, larynx, and nasopharynx.  Approximately 90% of all these tumors are represented by squamous cell carcinomas (SCC) with over 50% of them arising in the oral cavity. The most well-established risk factors associated with the same include excessive alcohol consumption, tobacco use, and human papillomavirus (HPV) infection. Oral and pharyngeal tumors account for the sixth most common types of cancers worldwide. Oral cancer is a lethal disease with a low survival rate as witnessed during the last few decades. This discrepancy can be explained by two reasons:

1)     Delay in the diagnosis

2)     High tumor recurrence rates

The risk of death increases when the patients aren’t diagnosed at an early stage.

Importance of Early Detection

Early detection increases the chances of successful treatment. The two major constituents of early detection involve – screening and education for promoting early diagnosis. Early diagnosis helps recognize possible warning signs and take prompt action. The disease can be effectively tackled when there is an increased awareness of the possible warning signs among nurses, physicians, and other health care providers.

Screening– Screening is a strategy developed to detect a disease in an individual without any visible symptoms. The purpose is the early identification of the disease. Conventional oral examination (COE) is the most common method of oral cancer screening. Although the method is quite useful to discover certain oral lesions, its ability to identify all oral premalignant lesions remains controversial. Being a subjective test, the accuracy also depends on the expertise of the doctor.

The current identification of oral cancers and potentially malignant disorders relies on biopsy of the target tissue and is followed by a histopathological assessment by a trained pathologist. Although the method is considered a gold standard for cancer identification, it has several limitations. Tissue biopsy is expensive, invasive and often time-consuming procedure. The diagnosis interpretation also suffers from both inter and intra-observer variability. Therefore, there has been greater emphasis on developing newer screening tools to accurately detect oral cancer in the early stages.  Oral cancer symptoms and treatment options must be carefully evaluated when a patient is doubtful.

Optical technologies have the ability to offer real-time assessment in a minimally invasive way while also eliminating longer waiting time and offering assistance in biopsy site selection. One optical technique that is exceedingly accurate in oral lesion detection is autofluorescence. Many other early detection methods have also been developed such as Toluidine Blue (TBlue).

Since oral cancer is fatal when detected late, one must visit the best hospitals for cancer treatment for early and accurate detection.